622 results about "Gonad" patented technology

A method for protecting at least one gonad from a blood borne cytotoxic drug, the method comprising reducing blood flow to at least one gonad of a patient undergoing cytotoxic treatment for an occlusion time interval, and allowing blood flow to the at least one gonad to resume after the occlusion time interval. Optionally the method is performed to protect an ovary during chemotherapy treatment.

A pharmaceutical composition comprising: (A) an androgen; (B) a cyclic enhancer of the type used in the compositions and methods claimed by U.S. Pat. No. 5,023,252 to Hsieh; and (C) a thickening agent; including, for example, a composition in which the cyclic enhancer is a macrocyclic ester or a macrocyclic ketone; the use of the composition to treat a condition, for example, male hypogonadism, in a patient by applying the composition to the membrane of the patient; and a method for making the composition.

The invention relates to a totally artificial breeding method for Coilia ectenes, belonging to the technical field of fish culture. The method is characterized by comprising the following process steps of parent fish source; parent fish select breeding comprising standing / flowing water combined reinforced breeding; artificial induced spawning measure comprising parent fish selection, semen collection, dug roe inspection, induced spawning water temperature confirmation, parent fish matching, hormone injection, artificial insemination and the like; microflow water incubating; and summer flower and fish fry breeding. The invention promotes the parent fish sex gland to grow to maturity and ovulate by measures of reinforcing parent fish nutrition reinforced breeding, feeding hormone, flowing water stimulating and regulating and the like and normalizes the artificial induced spawning and insemination process, originally creates a simple flowing water incubating device of a pelagic egg and reinforces the management and ecological regulation of incubation period, thereby effectively solving the technical problems of artificially breeding Coilia ectenes. The induced spawning rate of artificial breeding is 33 percent, the fertilization rate is 48 percent and the hatching rate is 44 percent.

The present invention relates to a synthetic process for the preparation of a novel class of androgen receptor targeting agents (ARTA) which demonstrate androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. The agents define a new subclass of compounds which are selective androgen receptor modulators (SARM) which are useful for a) male contraception; b) treatment of a variety of hormone-related conditions, for example conditions associated with Androgen Decline in Aging Male (ADAM), such as fatigue, depression, decreased libido, sexual dysfunction, erectile dysfunction, hypogonadism, osteoporosis, hair loss, anemia, obesity, sarcopenia, osteopenia, osteoporosis, benign prostate hyperplasia, alterations in mood and cognition and prostate cancer; c) treatment of conditions associated with Androgen Decline in Female (ADIF), such as sexual dysfunction, decreased sexual libido, hypogonadism, sarcopenia, osteopenia, osteoporosis, alterations in cognition and mood, depression, anemia, hair loss, obesity, endometriosis, breast cancer, uterine cancer and ovarian cancer; d) treatment and / or prevention of chronic muscular wasting; e) decreasing the incidence of, halting or causing a regression of prostate cancer; f) oral androgen relacement and / or other clinical therpauetic and / or diagnostic areas. The process of the present invention is suitable for large-scale preparation, since all of the steps give rise to highly pure compounds, thus avoiding complicated purification procedures which ultimately lower the yield. Thus the present invention provides methods for the synthesis of non-steroidal agonist compounds, that can be used for industrial large-scale synthesis, and that provide highly pure products in high yield.

This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. Other SARM compounds have been found to have an unexpected antiandrogenic activity of a nonsteroidal ligand for the androgen receptor. The SARM compounds, either alone or as a composition, are useful for a) male contraception; b) treatment of a variety of hormone-related conditions, for example conditions associated with Androgen Decline in Aging Male (ADAM), such as fatigue, depression, decreased libido, sexual dysfunction, erectile dysfunction, hypogonadism, osteoporosis, hair loss, anemia, obesity, sarcopenia, osteopenia, osteoporosis, benign prostate hyperplasia, alterations in mood and cognition and prostate cancer; c) treatment of conditions associated with Androgen Decline in Female (ADIF), such as sexual dysfunction, decreased sexual libido, hypogonadism, sarcopenia, osteopenia, osteoporosis, alterations in cognition and mood, depression, anemia, hair loss, obesity, endometriosis, breast cancer, uterine cancer and ovarian cancer; d) treatment and / or prevention of acute and / or chronic muscular wasting conditions; e) preventing and / or treating dry eye conditions; f) oral androgen replacement therapy; and / or g) decreasing the incidence of, halting or causing a regression of prostate cancer.

I disclose a method of treating a reproductive endocrine disorder in a patient, including coupling at least one electrode to at least one portion of a cranial nerve of the patient; and applying an electrical signal to said cranial nerve using said electrode to treat said reproductive endocrine disorder. Among the reproductive endocrine disorders which may be treated by the method are gonadal dysgenesis, hypogonadism, hypergonadism, delayed puberty, amenorrhea, infertility, premature menopause, and polycystic ovarian disease.

The invention discloses a giant salamander imitative-ecological taming and breeding method which is characterized in that an imitative-ecological taming and breeding technology is used, an environment suitable for giant salamander survival and growing is established, damage on giant salamanders from natural enemies and various natural disasters is avoided, taming and breeding pools suitable for giant salamanders in different ages are established, a staging taming and breeding technology is used, damage between giant salamander individuals is lowered to the maximum degree, meanwhile, the technology of natural egg laying, natural fertilization and artificial incubation is used, and the breeding emergence rate of the giant salamanders is improved. In a giant salamander parent cultivating stage, optimized fodder with added Chinese herbal medicine which can promote gonad maturing is fed, breeding speed is accelerated, and economic benefit is improved.

The invention provides an artificial Siberian sturgeon propagating method and a hatch device. The artificial propagating method includes six steps of selecting parent sturgeon, parent sturgeon breeding, artificial parturition facilitating, artificial fertilization, hatch and fry breeding. Lowering the water temperature artificially when breeding the parent sturgeon and injecting sturgeon pituitary can stimulate the gonad of the parent sturgeon to grow mature in advance. Artificial fertilization, hatch and fry breeding can solve the influence of limitation of the season and region on the Siberian sturgeon, and then the fine fry of the Siberian sturgeon can be provided stably and continuously to meet the available requirement for the fine sturgeon fry from the culturist all through the year. The hatch device includes a water providing pipe, a water inlet pipe and a water distributing pipe. An overflow opening is also arranged on the upside of the fry collecting pipe hatch bottle parallel arranged on the edge of the hatch bottle, a temporary feeding pond is arranged on the bottom of the lower end of the fry collecting pipe. The hatched fry can enter into the fry collecting pipe through the overflow opening, and then enter into the temporary feeding pond, and then the automatic fry collecting effect is realized, the invention dispenses with manual collecting as well as lowers the labor intensity greatly.

The invention discloses a hippocampus kelloggi artificial breeding method. According to the method, male and female hippocampuses, which are aged 1-2 and are healthy, intact, large and fat, are selected to be parent hippocampuses and then separately raised inside nursery ponds; after a period of intensive breeding, the gonad of the parent hippocampuses are nearly mature, during the breeding process, artificial heating is necessary, then the parent hippocampuses are polycultured and then spawn at a individual ratio of 1:1; female hippocampuses in the parenting period are intensively bred and protected, the operation is required to be soft and rapid, the out-water duration cannot be too long and the temperature difference should be less than 2-3 DEG C for avoiding abortion of the male hippocampuses; after giving birth, the male hippocampuses need to be removed out immediately for being bred away from hippocampus fry and accordingly are prevented from devouring or harming the hippocampus fry. The hippocampus kelloggi artificial breeding method provides technical support and theoretical foundation for large-scale commercialized hippocampus culture. According to the hippocampus kelloggi artificial breeding method, the breeding cost is reduced by 50-60%, breeding water quality can be easily controlled through the detection of various water quality indicators before hippocampus stocking, further high survival rate and high growth rate of the hippocampuses can be guaranteed.

The present invention relates to the protection of medical patients and personnel from harmful radiation. More specifically, this invention provides a compact, light-weight article to be worn in areas of the body most sensitive to radiation. These include, for example, the pelvic area, the genital and gonad areas, the breast area to guard against radiation to the mammary gland, the neck and throat to protect the thyroid gland, the eye area to protect the crystalline lens.