The invention discloses giant salamander compound bait and a production method thereof. The giant salamander compound bait includes bait for young salamanders and adult salamanders and bait for parent salamanders. The salamander compound bait takes fresh crucian carps, carps, grass carps, loaches and bull frogs as main materials and takes aggregates, mineral powder, micro amino acid and the like as auxiliary materials. After the main materials are mixed and minced, the auxiliary materials are added, and starch is then mixed. After being stirred and rubbed, the materials are filled by plastic casings in a sausage stuffer and dotted. Finally, sausages are sterilized at a temperature of 95-100 DEG C. The giant salamander compound bait can replace fresh fish and shrimp bait to feed giant salamanders. When the giant salamander compound bait is used for feeding, the plastic casings are stripped off, and the giant salamander compound bait is cut into strip materials suitable for the giant salamanders to swallow and thrown into a salamander pond. The giant salamander compound bait has good palatability. Practices prove that when the bait is used for feeding the giant salamanders, the breeding cost of the giant salamanders can be reduced by 30-50%, the growth rate of commercial salamanders can be increased by 10-30%, the salamander reproduction rate can be increased by 50-100%, and thedisease incidence rate of the giant salamanders is obviously reduced.