74results about How to "Promote growth and differentiation" patented technology

The invention relates to a preparation method of an oral biofilm. The preparation method comprises the following steps: adding type I collagen protein into an acetic acid solution to prepare a collagen-acetic acid swelling solution; adding chondroitin sulfate and stirring to prepare a collagen-chondroitin sulfate serous fluid; carrying out vacuum freeze-drying; pressing to prepare a collagen composite film; spraying the collagen-chondroitin sulfate serous fluid between two layers of the collagen composite film, and carrying out vacuum freeze-drying; carrying out high temperature vacuum crosslinking; and sterilizing after crosslinking to obtain a collagen-chondroitin sulfate composite oral biofilm. The invention has the following beneficial effects: the oral biofilm prepared by the above method has good histocompatibility, suitable controllable degradability and absorbability, low antigenicity and good plasticity and mechanical property; the oral biofilm is used in oral operation; and the three-dimensional porous structure of the oral film provides a tissue engineering scaffold for repairing of wounded tissues, is beneficial to invasion of cells and differential growth and can induce reparative regeneration of defective tissues, and specific thickness of the biofilm can effectively prevent ingrowth of soft tissue.

Disclosed herein are compositions of CPG 15-2 and methods for treating conditions of excessive cell death, such as neurological conditions, using such compositions. Compounds that inhibit the activity of CPG 15-2 are also disclosed herein for the treatment of conditions of undesirable cell survival, such as cancer.

The invention relates to a double-layer structure periosteum for diabetic bone repair and a preparation method thereof, belonging to the field of biomedical materials. Double-layer periosteum, the inner layer is chitosan / polyvinyl alcohol / calycosin blended in a certain proportion of porous structure sponge-like nanofiber layer, the outer layer is polydioxanone nanofiber layer, electrospun Composite preparation of silk technology. In the double-layer structure periosteum of the present invention, the outer layer has suitable mechanical properties, can effectively support the bone defect site, and prevent other soft tissues from growing in; the inner layer is loose and porous, suitable for the growth, attachment and reproduction of osteoblasts, And can play antibacterial antibacterial, hypoglycemic and other functions. The composite function of the inner and outer layers of the periosteum of the double-layer structure makes it beneficial to the growth of bone cells and the repair of bone tissue, and has the characteristics of simple preparation process and convenient operation.