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1237 results about "Skin damage" patented technology

Skin diagnostic imaging method and apparatus

A method and apparatus is provided for identifying imperfections in a person's facial, forearm or hand skin and for recommending an appropriate remedial cosmetic. The method includes providing an apparatus having a programmable computer, a camera connected to the computer, at least one visible wavelength light source for separately generating at least two different color images and at least one ultraviolet wavelength light source for an ultraviolet light image. Further, the method includes placing the ultraviolet and color images into a program of the computer and processing the images for pinpointing areas of skin requiring preventative treatment including those with skin damage. A remedial set of cosmetic products can thereby be recommended.
Owner:UNILEVER HOME & PERSONAL CARE USA DIV OF CONOPCO IN C

Skin resurfacing and treatment using biocompatible materials

Biocompatible materials are propelled at the skin with sufficient velocity to cause desired resurfacing of skin layers to the desired penetration depth. The materials, such as dry ice or water ice, are harmonious with the human body and thus eliminate foreign body reactions. Various materials may be used in combination, including local anesthetics and vasoconstrictors in solid or liquid form. The biocompatible solid or liquid particles are suspended in a cold carrier fluid and propelled through an insulated delivery system to the surface of the skin. The treatment of diseased skin lesions may be accomplished using the present invention as a drug delivery system.
Owner:PEARL TECHNOLOGY HOLDINGS LLC

Topical compositions comprising benfotiamine and pyridoxamine

InactiveUS20060045896A1Inhibition formationPrevention and treatment of damageBiocideOrganic active ingredientsHypopigmentationWrinkle skin
The present invention provides a composition comprising an effective amount of benfotiamine and an effective amount of pyridoxamine in a suitable vehicle for topical application. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles, loss of elasticity, and hyperpigmentation caused by chronoaging and / or photoaging of skin, by inhibiting particularly skin damage resulting from reactive carbonyl species (RCS), glycation of skin proteins, formation of advanced glycation endproducts (AGEs) and formation of advanced lipoxidation endproducts (ALEs).
Owner:TRACIE MARTYN INT

Transdermal and topical administration of drugs using basic permeation enhancers

Methods are provided for enhancing the permeability of skin or mucosal tissue to topical or transdermal application of pharmacologically or cosmeceutically active agents. The methods entail the use of a base in order to increase the flux of the active agent through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. The permeation enhancer can be an inorganic or organic base. Compositions and transdermal systems are also described.
Owner:DERMATRENDS INC

Amide substituted indazoles as poly(ADP-ribose)polymerase(PARP) inhibitors

The present invention relates to compounds of formula I:and pharmaceutically acceptable salts, stereoisomers or tautomers thereof which are inhibitors of poly (ADP-ribose) polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes, neurodegenerative diseases, retroviral infection, retinal damage or skin senescence and UV-induced skin damage, and as chemo- and / or radiosensitizers for cancer treatment.
Owner:MERCK SHARP & DOHME LLC

Digital skin lesion imaging system and method

InactiveUS7162063B1Easy to useReadily accurately identifyImage enhancementImage analysisDisplay deviceImage scale
New or significantly changed skin lesions are detected by providing digital baseline image data of an area of a subject's skin by placing a calibration piece on the area and then positioning a digital camera to frame the area within a field of view of the camera and digitally photographing the area to produce a digital baseline image of the area. The digital baseline image is downloaded from the camera to a computer, which digitally filters the baseline image to produce a partially transparent baseline image scaled to fit over a viewfinder display of the camera. The filtered baseline image is printed on a transparent sheet to produce template. Substantially later, a calibration piece is placed on the area, and the template is placed over the viewfinder display of the camera. The camera is positioned to frame that area within the field of view so as to align a live image of the area with the baseline image on the template. The area is photographed to produce a digital current image thereof. The current image is downloaded to the computer, which is operated to alternately display the aligned current image data and the baseline image data to allow visual identification of lesions which changed enough in the “alternating image comparison display” to identify a new or significantly growing lesion.
Owner:WESTERN RES

Delivery System And Method To Deliver Homeopathic Complexes Comprising Homeopathic Colored Pigment Products For Cosmetic Use

The present invention provides a delivery system and method to deliver topically homeopathic amounts of at least one Homeopathic Complex. It further provides a Homeopathic Colored Pigment Product containing a coloring agent having a plurality of particles having at least one surface and a homeopathically effective amount of at least one Homeopathic Complex, wherein the at least one surface of particles in the plurality of particles of the coloring agent contains the at least one Homeopathic Complex. It also provides cosmetic formulations containing the Homeopathic Colored Pigment Product for normal skin, problem skin, aged skin, and skin damaged by the harmful rays of the sun.
Owner:LURIA HENRY STEVEN +1

Treatment and prevention of abnormal scar formation in keloids and other cutaneous or internal wounds or lesions

The present invention relates to findings that reducing the activity of Plasminogen Activator Inhibitor-1 (PAI-1) suppresses an excessive deposition of collagen which is known as a cause for the formation of abnormal scars. These abnormal scars include but are not limited to keloids, adhesions, hypertrophic scars, skin disfiguring conditions, fibrosis, fibrocystic conditions, contractures, and scleroderma, all of which are associated with or caused by an excessive deposit of collagen in a wound healing process. Accordingly, aspects of the present invention are directed to the reduction of PAI-1 activity to decrease an excessive accumulation of collagen, prevent the formation of an abnormal scar, and / or treat abnormal scars that result from an excessive accumulation of collagen. The PAI-1 activity can be reduced by PAI-1 inhibitors which include but are not limited to PAI-1 neutralizing antibodies, diketopiperazine based compounds, tetramic acid based compounds, hydroxyquinolinone based compounds, Enalapril, Eprosartan, Troglitazone, Vitamin C, Vitamin E, Mifepristone (RU486), and Spironolactone to name a few. Another aspect of the present invention is directed to methods of measuring PAI-1 activity in a wound healing process and determining the propensity of the formation of an abnormal scar.
Owner:CHILDRENS HOSPITAL OF LOS ANGELES +1

Apparatus and method for penetrating oilbearing sandy formations, reducing skin damage and reducing hydrocarbon viscosity

A shaped charge and a method of using such to provide for large and effective perforations in oil bearing sandy formations while causing minimal disturbance to the formation porosity is described. This shaped charge uses a low-density liner having a filler material that is enclosed by outer walls made, preferably, of plastic or polyester. The filler material is preferably a powdered metal or a granulated substance, which is left largely unconsolidated. The preferred filler material is aluminum powder, or aluminum particles, that are coated with an oxidizing substance, such as TEFLON®, permitting a secondary detonation reaction inside the formation following jet penetration. The filled liner is also provided with a metal cap to aid penetration of the gun scallops, the surrounding borehole casing and the cement sheath. The metal cap forms the leading portion of the jet, during detonation. The remaining portion of the jet is formed from the low-density filler material, thereby resulting in a more particulated jet. The jet results in less compression around the perforation tunnel and less skin damage to the proximal end of the perforation tunnel.
Owner:OWEN OIL TOOLS

Microemulsions to convert OBM filter cakes to WBM filter cakes having filtration control

Single phase microemulsions improve the removal of filter cakes formed during drilling with oil-based muds (OBMs). The single phase microemulsion removes oil and solids from the deposited filter cake. Optionally, an acid capable of solubilizing the filter cake bridging particles may also be used with the microemulsion. In one non-limiting embodiment the acid may be a polyamino carboxylic acid. Skin damage removal from internal and external filter cake deposition can be reduced. In another optional embodiment, the single phase microemulsion may contain a filtration control additive for delaying the filter cake removal, destruction or conversion.
Owner:BAKER HUGHES INC

Antioxidant Compositions and Methods of Using the Same

The invention provides non-irritating, stable topical compositions including at least Vitamin C, Vitamin E and a polyphenol antioxidant. Such compositions can be used to facilitate the prevention or treatment of free oxygen, nitrogen, and / or other free radical related skin damage. Also provided are methods for modifying free radical damage to skin by administering such compositions in an amount sufficient to treat and / or prevent free radical damage to the skin.
Owner:ANTEIS SA

Skin resurfacing device

A skin resurfacing device for peeling the outermost layer of the skin for renewing the skin surface and repairing skin damage including a housing, a skin sensor, and a skin treater. The skin treater consists of an abrasive tip, a first end, a transparent portion, a first filter, and a second end, all of which are detachable and replaceable. The skin treater is connected to a vacuum source by a tubular hose. The vacuum provides both closeness of contact between the abrasive tip and the user's skin and the suctioning of skin debris peeled off. The skin treater, especially the abrasive tip are made with common material and mass production process so that they are disposable and economic.
Owner:CHUNG TAE JUN

Preparation method and application of sericin hydrogel

ActiveCN103951831AGood natural propertiesOvercoming the challenge of high biological properties of sericinNervous disorderPeptide/protein ingredientsCross-linkDisease
The invention discloses a preparation method of sericin hydrogel, the method is as follows: first, weighting domestic silkworm fibroin deletion form mutation variety silkworm cocoon for LiBr or LiCl extraction and dialysis and purification to obtain a non-degradable sericin water solution with a mass percentage concentration of 0.1-4%; concentrating the sericin water solution to 1.5-10%, adding a cross-linking agent to the concentrated sericin water solution (wherein 2-500muL of the cross-linking agent is added into each L of the sericin water solution), fully mixing, and placing at 4-45 DEG C for 5 seconds to 36 hours to obtain the sericin hydrogel. The sericin hydrogel has biological activity and multiple functions, can be used as carrying growth factors, drugs and cell carriers treatment, and can be applied in repair of a variety of soft tissue injuries, including but not limited to skin damages, muscle damages, injuries of blood vessel, nerve injuries, myocardial damages, and the like, and treatment of diseases.
Owner:XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV

Methods for treating skin lesions

Methods for diagnosing skin lesions are disclosed. Generally, the method include topically administering an IRM compound to a treatment area for a period of time and in an amount effective to cause a visible change in the appearance of a skin lesion including, in some cases, causing subclinical lesions to become visible. Suitable IRM compounds include agonists of one or more TLRs.
Owner:3M INNOVATIVE PROPERTIES CO

Moisture wicking adhesives for skin-mounted devices

The present invention describes breathable multilayered adhesive structures that can be used as adhesives to mount devices onto the skin. The breathable multilayered adhesive structures can comprise moisture-wicking layers adhered to the skin by a porous adhesion layer. The pores allow moisture released from the skin to be transferred away through the moisture-wicking layer. The adhesive structures permit the devices to be skin-mounted for an extended period of time (e.g., a few hours or days) without causing moisture-associated skin injuries such as erythema, maceration, and irritation or inflammation.
Owner:MC 10 INC

Portable laser and process for pain research

A process and laser system for in vitro and in vivo pain research, pain clinical testing and pain management. In preferred embodiments of the present invention a diode laser operating at a 980 nm wavelength is used to produce warmth, tickling, itching, touch, burning, hot pain or pin-prick pain. The device and methods can be used for stimulation of a single nerve fiber, groups of nerve fibers, nerve fibers of single type only as well as more the one type of nerve fibers simultaneously. The present invention is especially useful for research of human / animal sensitivity, pain management, drug investigation and testing, and psychophysiology / electrophysiology studies. The device and methods permit non-contact, reproducible and controlled tests that avoid risk of skin damage. Applicant an his fellow workers have shown that tests with human subjects with the process and laser of the present invention correlate perfectly with laboratory tests with nerve fibers of rats. The device and the methods can be applied in a wide variety of situations involving the study and treatment of pain. Preferred embodiments of the present invention provide laser systems and techniques that permit mapping and single mode activation of C fibers and A-delta fibers.
Owner:NEMENOV MIKHALL

Methods and devices for the treatment of skin lesions

Methods and devices for the treatment of skin lesions resulting from bacterial, fungal or viral infections or from exposure to irritants are disclosed. The invention relates methods and devices for delivering a controlled dose of thermal energy to the infected or irritated tissue and thereby speed the recovery process.
Owner:LUMATHERM INC

Non-invasive screening of skin diseases by visible/near-infrared spectroscopy

A non-invasive tool for skin disease diagnosis would be a useful clinical adjunct. The purpose of this study was to determine whether visible / near-infrared spectroscopy can be used to non-invasively characterize skin diseases. In-vivo visible- and near-infrared spectra (400-2500 nm) of skin neoplasms (actinic keratoses, basal cell carcinomata, banal common acquired melanocytic nevi, dysplastic melanocytic nevi, actinic lentigines and seborrheic keratoses) were collected by placing a fiber optic probe on the skin. Paired t-tests, repeated measures analysis of variance and linear discriminant analysis were used to determine whether significant spectral differences existed and whether spectra could be classified according to lesion type. Paired t-tests showed significant differences (p<0.05) between normal skin and skin lesions in several areas of the visible / near-infrared spectrum. In addition, significant differences were found between the lesion groups by analysis of variance. Linear discriminant analysis classified spectra from benign lesions compared to pre-malignant or malignant lesions with high accuracy. Visible / near-infrared spectroscopy is a promising non-invasive technique for the screening of skin diseases.
Owner:NAT RES COUNCIL OF CANADA

Use of polyphenols to treat skin conditions

InactiveUS20030175234A1Reduce skin of skin of skinReduce surfaceBiocideCosmetic preparationsWrinkle skinHypopigmentation
A composition is provided to treat and / or prevent for treating skin conditions including fine lines and wrinkles, acne rosacea, surface irregularities of the skin and hyper-pigmentation melasma of the skin, which includes use of a topically applied composition such as an ointment, lotion, cream, serum, gel or pad applied formulation, containing an effective amount of polyphenols, such as green tea based polyphenols, including but not limited to catechins, such as epigallocatechin gallate (EGCG), epigallocatechin (EGC), epicathechin 3-gallate (ECG) and epicatechin (EC). The formulation is preferably composed of 90 percent polyphenol isolates, derived from green tea with potent antioxidant properties, to assist in minimizing free-radical induced skin damage.
Owner:TOPIX PHARMA INC

Hand health and hygiene system for hand health and infection control

ActiveUS20090191248A1Prevent and overcome skin damageGood for healthCosmetic preparationsBiocideIrritationHand sanitizer
The present disclosure is directed to a system and methods for maintaining or improving hand health and hygiene. More particularly, the system and methods prevent or overcome skin damage caused by frequent hand washing and use of hand sanitizers and / or cleansers. The hand care system comprises an article, such as an elastomeric glove, that has a moisturizing liquid liner composition on the skin-contacting surface of the article that delivers a skin health benefit to the skin, a non-irritating hand cleanser capable of moisturizing the skin, and a moisturizing hand sanitizer.
Owner:KIMBERLY-CLARK WORLDWIDE INC

Alginate-based hydrogel dressing and preparation method thereof

The invention relates to an alginate-based hydrogel dressing and a preparation method thereof, and belongs to the technical field of medical supplies. Raw materials of the invention are a compound of sodium alginate or other alginates and a thickener, a moisturizer and other functional matters, are subjected to swelling dosing, pre-crosslinking, film coating, spray crosslinking, constant-temperature crosslinking plasticizing and film-covering shear forming, and are then prepared into a three-dimensional water-containing grid structure through covalent cross-linking and ion cross-linking. The medical hydrogel dressing is a topical gel dressing, has good moisturizing performance, toughness and adhesion, is mainly suitable for superficial skin damage, such as cut wound, lacerated wound, scratch, burns, suture wounds and the like, protects skin wound healing of a patient, has effects of easing pain, inhibiting bacteria, resisting inflammation, keeping the wound moist, promoting wound healing, and improving the wound repairing quality, is more suitable for treating bedsore wounds, ulcer wounds and other sites hard to be bound after a surgery, can also be used for non-wound sites, and plays a role of moisturizing.
Owner:QINGDAO CHENLAND MARINE BIOTECH CO LTD

Anti-skin damage compositions with complimentary dual mode of action

Disclosed are skin care compositions exerting a novel complementary dual mode of action in protecting the skin from day-to-day insults. The skin care compositions of the present invention comprise the extract from the liquid endosperm of Cocos nucifera as the principle ingredient along with one or more actives including the fruit rind extracts of Garcinia cambogia, Garcinia indica and Garcinia mangostana, seed coat extract of Tamarindus indicus, Chlorogenic acid extract from the beans of Coffea arabica, seed extracts of Nelumbo species, the leaf extracts of Murraya koenigii and the triterpene pentapeptides of oleanolic acid and ursolic acid. While the extract of Cocos nucifera has been included as a nutritional supplement (a natural cell culture medium) to ensure the maintenance of the viability and constant renewal of the cells of the skin, the other actives have been carefully chosen based on one or more of their effective skin care properties. The compositions of the present invention offer a safe prophylactic / therapeutic management solution to the wide range of pathological states associated with skin insults and the associated psycho-social issues.
Owner:SAMI LABS LTD

Methods, devices and systems for hair removal

Methods, Devices and systems for hair removal combine the application of RF electromagnetic energy to the skin with application of heat from heating element(s) to hair(s) of the skin. The devices or systems may include RF electrodes and one or more heating elements. RF energy from an RF generating unit is applied to the RF electrodes. Heat is applied to hair shafts by the heating element(s). The devices and systems may be hand held or may include a hand held part connected to a base unit. In operation, the hand held device or part is moved along the treated skin region. The combined effect of RF energy application to the skin and heating of the hair shaft results in improved hair removal and may reduce hair re-growth. The devices and systems may also include safety improving features preventing skin damage by reducing sparking or excessive skin heating by the heating element(s).
Owner:LECTYS

Near-infrared super-continuum lasers for early detection of breast and other cancers

A system and method for using near-infrared or short-wave infrared (SWIR) light sources for early detection and monitoring of breast cancer, as well as other kinds of cancers may detect decreases in lipid content and increases in collagen content, possibly with a shift in the collagen peak wavelengths and changes in spectral features associated with hemoglobin and water content as well. Wavelength ranges between 1000-1400 nm and 1600-1800 nm may permit relatively high penetration depths because they fall within local minima of water absorption, scattering loss decreases with increasing wavelength, and they have characteristic signatures corresponding to overtone and combination bands from chemical bonds of interest, such as hydrocarbons. Broadband light sources and detectors permit spectroscopy in transmission, reflection, and / or diffuse optical tomography. High signal-to-noise ratio may be achieved using a fiber-based super-continuum light source. Risk of pain or skin damage may be mitigated using surface cooling and focused infrared light.
Owner:OMNI MEDSCI INC

A dermatoscope image segmentation method based on a multi-branch convolutional neural network

The invention discloses a dermatoscope image segmentation method based on a multi-branch convolutional neural network. The method comprises the following steps of 1, collecting training samples; 2, expanding the image; 3, designing a multi-branch convolutional neural network model; 4, training the multi-branch convolutional network; 5, generating a skin damage distribution probability graph; 6, obtaining a segmentation result. The method has the advantages that the training data set is effectively expanded by using the corresponding image transformation according to the data characteristics ofthe dermatoscope image, so that the network training is effective, and the generalization performance is high; the convolutional neural network comprises a plurality of branches, rich semantic information and detail information are fused, compared with a common network, the skin lesion edge can be better recovered, and a more accurate skin lesion segmentation result is obtained; the method is a full-automatic segmentation scheme, only the dermatoscope image to be segmented needs to be input, the segmentation result of the image can be automatically given through the scheme, the additional processing is not needed, and the method is efficient, simple and convenient.
Owner:BEIHANG UNIV
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