The invention relates to a formula of drink capable of moderating liquor and neutralizing the liquor and a production process thereof. The drink formula comprises the following components: 10 parts of Radix Puerariae, 3 parts of honey raisin tree, 2 parts of pericarpium citri reticulatae, 1 part of chrysanthemum, 0.6 part of liquorice, 10 parts of lemon juice or other fruits used as fruit raw materials, 3 parts of honey, defined amount of corresponding fruit juice food flavor and defined amount of white granulated sugar. The preparation procedure comprises the following steps of: raw material selecting, crushing and evenly stirring, ethanol extraction, filtering, concentration, alcohol precipitation, filtering and spraying and drying to obtain water-soluble dry powder; heating purified water to 40-50 DEG C, adding the water-soluble dry powder, adding the honey and the white granulated sugar, adding the fruit juice, adding the corresponding fruit juice food flavor, canning, capping, sterilizing (sterilizing for 30 min at 100 DEG C), cooling, verifying, labeling and casing and warehousing finished products. The drink can accelerate the human body to decompose acetaldehyde to rapidly discharge the acetaldehyde out of the body, thereby preventing people from generating drunk symptoms, such as headache, giddiness, local skin allergy, gastroenteritis and the like and achieving the goals of moderating and neutralizing the liquor.