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257 results about "Crosslinked chitosan" patented technology
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Biocidal compositions for treating water
InactiveUS6093422AEffective destructionEfficient Growth InhibitionOrganic active ingredientsBiocideCrosslinked chitosanSulfate zinc
The present invention is directed to a biocidal water treatment composition, water treatment apparatus, and method of treating water to reduce levels of pathogens. The composition contains sources of copper, zinc, and silver metal ions within a crosslinked polymer matrix. Examples of these ion sources include copper sulfate, zinc sulfate, and silver nitrate. An example of the crosslinked polymer matrix is crosslinked chitosan, which also serves to clarify the water and release the metal ions over time. The product is easy to manufacture, and allows the use of decreased halogen sanitizer, as well as decreased copper ion, thereby decreasing the likelihood of staining. The product simultaneously provides good bactericidal and algaecidal properties, despite low levels of copper ion and low chlorine levels.
Owner:ZODIAC POOL SYST
Biocidal compositions for treating water
InactiveUS6217780B1Effective destruction and growth inhibitionHigh degreeBiocideDead animal preservationCrosslinked chitosanStaining
Owner:ZODIAC POOL SYST
Biocompatible and bioabsorbable derivatized chitosan compositions
ActiveUS20140275291A1Reduces unnecessary riskQuick controlCompounds screening/testingBiocideCrosslinked chitosanChemical composition
The invention relates to biocompatible, bioabsorbable derivatized non-crosslinked chitosan compositions optionally crosslinked to gelatin / collagen by 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride (EDC) for biomedical use and methods of making and testing such compositions, including a modified acute systemic toxicity test. The compositions comprise derivatized chitosan reacetylated to a degree of N-deacetylation (DDA) of between about 15% and 40%. The compositions are typically bioabsorbed in about 90 days or less and can be made to bioabsorb at differing rates of speed. The compositions are initially soluble in aqueous solution below pH 6.5. The compositions have an acid content that can be adjusted between about 0% (w / w) and about 8% (w / w) to customize the composition for uses that require and / or tolerate differing levels of cytotoxicity, adhesion, composition cohesion, and cell infiltration into the composition.
Owner:TRICOL BIOMEDICAL INC
Multilayer films
InactiveUS20100062232A1Cosmetic preparationsMaterial analysis by observing effect on chemical indicatorCrosslinked chitosanMultilayer membrane
The present invention concerns multilayer films comprising a plurality of layers, at least some of the layers comprise (i) cross-linked chitosan, alginate, chondroitin sulfate, or hyaluronic acid and (ii) particles or void spaces; wherein the layers are 20-260 nm in thickness. Also disclosed are multilayer films comprising at least two of: a layer comprising a first polymer; a layer comprising a second polymer; a layer comprising particles, wherein said particles comprise ceramic material, metallic species, or both; and, a layer comprising a combination of said first polymer and said particles; wherein said multilayer film is capable of displaying structural color. Also provided are methods for making and using the inventive multilayer films and compositions comprising the multilayer films.
Owner:DREXEL UNIV
Citric acid-modified cyclodextrin crosslinking chitosan porous adsorption material, and preparation and application of same
InactiveCN107099049AImprove acid resistanceOvercome easily soluble in acidic solutionOther chemical processesWater contaminantsCrosslinked chitosanFreeze-drying
The invention relates to a citric acid-modified cyclodextrin crosslinking chitosan porous adsorption material, and preparation and an application of same. The preparation method includes the steps of: modifying beta-cyclodextrin with citric acid, performing amide crosslinking to a modified beta-cyclodextrin water solution with a chitosan solution under the effect of an EDC / NHS coupling agent, and freeze-drying the product to obtain the modified beta-cyclodextrin crosslinking chitosan porous adsorption material. In the invention, by means of the modified beta-cyclodextrin crosslinking chitosan, the acid resistance of chitosan is improved, and a defect that the chitosan material is liable to dissolve in an acidic solution and is difficult to recycle is overcome. In the invention, hydrogel is freeze-dried, so that chitosan-base porous materials in different shapes can be rapidly produced. The citric acid-modified cyclodextrin crosslinking chitosan porous adsorption material has excellent adsorption capability to anionic dyes; at room temperature, the material can reach 1060.41 mg / g in saturation adsorption quantity to reactive yellow BH-3RS.
Owner:DONGHUA UNIV
Method for preparing chitosan porous microsphere sorbent by metal ion imprinting and crosslinking methods as well as use
InactiveCN101347720AEfficient selection of separation functionsOther chemical processesWater/sewage treatment by sorptionHigh resistanceCrosslinked chitosan
The invention discloses a preparation method of a metallic ion blotting crosslinked chitosan porous spherical adsorbent and the application thereof; the method is as follows: the chitosan in solution state and metallic ions jointly form a composition which is prepared into microspheres with diameters from 1.0mm to 10.0mm, the prepared microspheres are treated with pre-crosslinking reaction and then crosslinking reaction in water solution, after crosslinking reaction, the metallic ions and pre-crosslinking agent used for blotting are removed and the metallic ion blotting crosslinked chitosan porous spherical adsorbent is obtained. The method of the invention jointly applies metallic ion blotting and the formaldehyde pre-crosslinking method and matches the technique of solidification and granulation in alkali solution to prepare the metallic ion blotting crosslinked chitosan porous spherical adsorbent with the diameter of 1.0-10.0mm. The spherical adsorbent has large size and high specific surface area, and can be applied to efficient selective separation of heavy metal ions; furthermore, the spherical adsorbent can solve the problems that the existing chitosan microsphere is mostly powder, and has small size and high resistance to water flows, and the speed of sewage treatment is affected, etc.
Owner:SOUTH CHINA NORMAL UNIVERSITY
Polyamido-amine dendrimers -modified macroporous crosslinked chitosan microsphere and preparation method thereof
InactiveCN101817932AImprove adsorption capacityHigh amino contentOrganic active ingredientsOther chemical processesDendrimerCrosslinked chitosan
The invention relates to a polyamido-amine dendrimers-modified macroporous crosslinked chitosan microsphere and a preparation method thereof, specifically a low-generation (Generation is not more than 3) polyamide-amine (Poluamidoamine, short for PAMAM) dendrimers (Dendrimers)-modified macroporous crosslinked chitosan microsphere and a preparation method thereof. The macroporous crosslinked chitosan microsphere is prepared by means of inverse suspension reaction by using chitosan as raw material, sucrose as pore forming agent, glutaric dialdehyde as crosslinking agent, and is then chemically modified by using low-generation (generation is not more than 3) polyamide-amine dendrimer as amination agent. The microsphere has the average particle diameter of 100 to 170 microns. The modified macroporous crosslinked chitosan microspheres CS-G0, CS-G1.0, CS-G2.0 and CS-G3.0 respectively have the content of amino: 4.63, 5.30, 5.41 and 4.84mmol / g. The microsphere has the advantages of: simple steps of the material preparation method thereof, increased amino content after the modification thereof, and higher adsorption performance than unmodified chitosan microspheres when being used for the adsorption of bilirubin in aqueous solution.
Owner:NANKAI UNIV +1
Method for preparing crosslinked-chitosan-system azo dye wastewater adsorbent
InactiveCN104741089ASimple structureHigh shapeOther chemical processesMicroballoon preparationCrosslinked chitosanMicron scale
The invention relates to a method for preparing a crosslinked-chitosan-system azo dye wastewater adsorbent. According to the method, the chitosan microsphere adsorbent aiming at azo dye wastewater treatment is prepared by carrying out reversed phase emulsification process and a cross-linking reaction on a microfluidic focusing type chip made from a laboratory-made polymethyl methacrylate (PMMA) material; the chitosan adsorbent prepared by virtue of the method belongs to a micron scale; compared with adsorbents at present, the chitosan adsorbent has the advantages that the specific surface area is larger, the degree of sphericity and the monodispersity are higher, the biocompatibility and the reproducibility of the chitosan adsorbent are guaranteed by virtue of a chitosan matrix, and the dissolving resistance and the swelling resistance of the chitosan adsorbent are improved under acid conditions when relatively high template dye adsorption capacity is guaranteed in a crosslinking process; by testing template dye wastewater methyl orange, the maximal adsorption capacity can reach 65.83mg / g.
Owner:EAST CHINA UNIV OF SCI & TECH
Polylactic acid-hydroxyacetic acid copolymer nano-drug carrier as well as preparation method and application thereof
ActiveCN104001178AImprove intake capacityEliminate side effectsNanomedicinePharmaceutical non-active ingredientsCrosslinked chitosanMicrosphere
The invention provides a PLGA (polylactic acid-hydroxyacetic acid) nano-drug carrier which is composed of PLGA nano microsphere kernel and an anillic aldehyde crosslinked chitosan housing. A preparation method of the polylactic acid-hydroxyacetic acid copolymer nano-drug carrier is as follows: dispersing a PLGA organic phase which takes dichloromethane and alcohol as a mixed solvent in a water phase to prepare PLGA microspheres by taking PVA (polyvinyl acetate) as an emulsifier by virtue of an one-off emulsion process; then, adding the PLGA microspheres into chitosan liquor, so that the chitosan is adsorbed on the surfaces of the PLGA microspheres, and then adding the chitosan on the surfaces of anillic aldehyde crosslinked PLGA microspheres. The product has a certain pH environmental responsiveness, can realize controlled release of the drug according to in-vivo pH environmental changes, is high in stability, strong in up-taking capacity for microsphere-coated medicaments by the cells, and has very good application prospect in the drug carrier for treating tumors.
Owner:SUN YAT SEN UNIV
Grafting method of ornamental elm
Owner:HENAN UNIV OF SCI & TECH
Preparation of chitosan-based microporous composite material and its applications
ActiveUS20130039822A1The material is lowCostTransuranic element compoundsRadium compoundsCrosslinked chitosanSorbent
Microporous glutaraldehyde-crosslinked chitosan sorbents, methods of making and using them, and a generator for the radioisotope 99Mo containing the sorbents.
Owner:PERMA FIX ENVIRONMENTAL SERVICES
Production method of crosslinked chitosan microsphere heavy metal ion adsorbent
InactiveCN102614838AWide variety of sourcesLow priceOther chemical processesCrosslinked chitosanEthylene diamine
The invention discloses a production method of a crosslinked chitosan microsphere heavy metal ion adsorbent. The method comprises the following steps of: (1) protecting amino on chitosan C2 with formaldehyde by taking chitosan as a material and taking liquid paraffin as an organic dispersion medium, and preparing a crosslinked chitosan microsphere with a reversed phase suspension crosslinking method; and (2) chemically grafting the crosslinked chitosan microspheres by taking the crosslinked chitosan microsphere as a parent body and taking ethylene diamine as a ligand to obtain the crosslinked chitosan microsphere heavy metal ion adsorbent. The crosslinked chitosan microsphere heavy metal ion adsorbent produced with the method has high selective adsorption on Cu<2+> ions.
Owner:ZHEJIANG GONGSHANG UNIVERSITY
Preparation method of cellulose acetate membrane surface crosslinked chitosan hydrophilic membrane
The invention provides a preparation method of a cellulose acetate membrane surface crosslinked chitosan hydrophilic membrane and belongs to the technical field of membrane surface modification. A cellulose acetate membrane is activated by an acid solution, and has coupling crosslinking with the acetic acid water solution of the chitosan, so that a hydrophilic membrane material of the cellulose acetate membrane surface crosslinked chitosan can be prepared. The preparation method of the invention is simple in technology, low in cost, natural, and environmentally-friendly. The cellulose acetate membrane modified by the method is good in hydrophillic nature and binding capability, is good in mechanical strength and mechanical toughness, can be widely applicable to the field of biochemistry, molecular biology and environment, such as the immunoassay, the protein and DNA (deoxyribonucleic acid) analysis, the colloidal gold detection card, the absorption and removal of the toxic and harmful substances in the environment such as the environmental hormone and the like, and can be taken as biomedical material due to the improvement of the mold resistance of a cellulose acetate membrane.
Owner:NANJING YITE BIOTECH
Irradiation crosslinked chitosan/gelatin/polyvinyl alcohol hydrogel dressing as well as preparation method and application thereof
ActiveCN103480034ARapid hemostasisLow toxicityAbsorbent padsBandagesCrosslinked chitosanBiocompatibility Testing
The invention discloses an irradiation crosslinking chitosan / gelatin / polyvinyl alcohol hydrogel dressing as well as a preparation method and an application thereof. The preparation method comprises the steps that a chitosan, gelatin and polyvinyl alcohol solution is prepared by using ultrapure water serving as a solvent; the solution is stirred and mixed uniformly and then irradiated, and original hydrogel is obtained; the original hydrogel is put into the ultrapure water to be soaked; and the chitosan / gelatin / polyvinyl alcohol hydrogel dressing is prepared. The hydrogel dressing is extensive in raw material source, simple in preparation technology and stable in performance, and has the advantages of inflammation diminishing, wound pain relieving, scar reduction, wound healing promotion, wound seepage absorption, and excellent biocompatibility. The hydrogel dressing is easy to degrade after abandoned, and has a smaller influence on an environment. The hydrogel dressing can be applied to the fields of trauma hemostasis, inflammation diminishing, scald, postoperative wound healing and the like.
Owner:江西金思康药业有限公司
Chitosan hemostatic material formed through covalent crosslinking and preparation method thereof
ActiveCN104474575ASimple manufacturing processReduce manufacturing costAbsorbent padsBandagesCrosslinked chitosanPolymer science
The invention discloses a chitosan hemostatic material formed through covalent crosslinking and a preparation method thereof. The chitosan hemostatic material formed through covalent crosslinking is obtained by chemically crosslinking chitosan by utilizing a crosslinking agent via covalent bonds, wherein the crosslinking agent is polyethylene glycol diglycidyl ether. The preparation method of the chitosan hemostatic material formed through covalent crosslinking comprises the following steps: 1) preparing chitosan into a water solution; 2) adding the crosslinking agent to the chitosan water solution, fully stirring and mixing the materials, then pouring the mixture into a mold, and freeze-drying the product, thus obtaining the chitosan hemostatic material, wherein the crosslinking agent is polyethylene glycol diglycidyl ether. The chitosan hemostatic material and the preparation method have the beneficial effects that chitosan is crosslinked by polyethylene glycol diglycidyl ether under acidic conditions; an ethylene oxide group in polyethylene glycol diglycidyl ether carries out ring-opening reaction with hydroxyl on chitosan under acidic conditions to form the crosslinked product by generating ether bonds; the crosslinking agent used in the method is relatively safe; the preparation process is simple and practicable and is lower in production cost.
Owner:LANZHOU KAIBO PHARMA
Dialdehyde starch crosslinked chitosan magnetic microsphere and preparation thereof
InactiveCN101343369ANo side effectsImprove bindingPharmaceutical non-active ingredientsAntineoplastic agentsCrosslinked chitosanCross-link
The invention relates to diadehyde starch cross-linking chitosan magnetic microsphere and the preparation method, and the diadehyde starch cross-linking chitosan magnetic microsphere belongs to the functional macromolecule material. The preparation method comprises the following steps: firstly, the diadehyde starch is prepared; secondly, the diadehyde starch cross-linking magnetic microsphere is prepared; and thirdly, the diadehyde starch cross-linking chitosan magnetic microsphere is prepared. The diadehyde starch cross-linking chitosan magnetic microsphere uses the magnetic microsphere prepared through the cross-linking reaction of the chitosan and the diadehyde starch, the magnetic microsphere has no toxic side effect to the human body. The diadehyde starch cross-linking chitosan magnetic microsphere prepared through the invention is used for the targeting drug carrier, and the diadehyde starch cross-linking chitosan magnetic microsphere contains a large quantity of aldehyde groups, which is convenient for the combination of the amino groups in the drug, thereby enhancing the drug carrying amount, and simultaneously after the drug arrives at the lesion location, which can be easily combined with the proteases in the human body, to fully exert the drug effect.. The diadehyde starch cross-linking chitosan magnetic microsphere and the preparation methodare particularly suitable for the treatment to the tumour.
Owner:HEZHOU UNIV
Preparation method of crosslinked chitosan/gelatin composite porous scaffold
InactiveCN103724657AGood mechanical propertiesHigh porosityProsthesisCrosslinked chitosanFreeze-drying
The invention belongs to the technical field of new materials, and particularly relates to a preparation method of a crosslinked chitosan / gelatin composite porous scaffold. According to the method, chitosan, gelatin and other natural biological materials are used as raw materials, an organosilane coupling agent is used as a crosslinking agent, and a freeze-drying process is utilized to prepare the excellent-mechanical-property crosslinked chitosan / gelatin composite porous scaffold composed of pure natural biological materials. The crosslinked chitosan / gelatin composite porous scaffold has the characteristics of high porosity, high pore strength, large pore diameter and the like; the pore size is 100-300 mu m, and the porosity is 90%; and the crosslinked chitosan / gelatin composite porous scaffold is in an open pore structure in which larger pores contains smaller pores, and thus, cells are suitable to be implanted on the scaffold surface. Compared with the chitosan scaffold, the crosslinked chitosan / gelatin composite porous scaffold has better mechanical properties; and the addition of the gelatin and organosilicon crosslinking agent is more beneficial to proliferation and differentiation of cells on the porous scaffold surface, and the crosslinked chitosan / gelatin composite porous scaffold has higher affinity for biological cells.
Owner:TONGJI UNIV
Polyethyleneimine modified chitosan microsphere medium as well as preparation and application methods thereof
ActiveCN104258830AHigh decolorization rateHigh ion exchange capacityOther chemical processesAlkali metal oxides/hydroxidesCrosslinked chitosanPolymer science
The invention relates to a polyethyleneimine modified chitosan microsphere medium. The medium adopts a crosslinked chitosan microsphere with aldehyde surface, wherein high molecular weight polyethyleneimine is modified on the surface; the weight of polyethyleneimine modified on the surface is 731 plus or minus 32 mu mol / g-1,275 plus or minus 37 mu mol / g according to the ion exchange capacity; the particle size of the polyethyleneimine modified chitosan microsphere medium ranges from 50 mu m to 200 mu m; and the molecular weight of polyethyleneimine molecules ranges from 1,200 to 60,000. According to the polyethyleneimine modified chitosan microsphere medium, the ion exchange capacity of the medium is improved, and accordingly, the decolorization ratio of the medium to dye wastewater is increased; the maximum ion exchange capacity of the polyethyleneimine modified chitosan microsphere medium can be 1,275 plus or minus 37 mu mol / g and is far higher than that of unmodified chitosan microsphere medium with the ion exchange capacity of 418 plus or minus 31 mu mol / g; and the modifying method is simple in process and low in cost.
Owner:HEBEI UNIV OF TECH
Crosslinked chitosan-biochar microsphere adsorbing material and preparation method thereof
PendingCN109364897AWell-developed pore structureAvoid secondary pollutionOther chemical processesWater contaminantsCrosslinked chitosanMicrosphere
The invention discloses a crosslinked chitosan-biochar microsphere adsorbing material. The material is prepared from chitosan, biochar powder and a crosslinking agent, and chitosan and the biochar powder are uniformly mixed. A preparation method of the material comprises the steps as follows: firstly, adding chitosan to a diluted acid solution and performing stirring to form sol; then, adding thebiochar powder to the sol and performing stirring to form mixed sol; next, dropping the mixed sol in an alkaline solution to form microspheres; after washing the microspheres to be neutral, soaking the microspheres in a crosslinking agent, and washing the microspheres with deionized water to be neutral after soaking. According to the crosslinked chitosan-biochar microsphere adsorbing material andthe preparation method thereof, the prepared crosslinked chitosan-biochar microspheres have the characteristics of advanced, rough and complex pore structures, have larger specific surface area, havegood adsorption capacity for heavy metal ions and organic dyes in water and can be completely recovered after use, and the secondary pollution problem due to the fact that chitosan and biochar are difficult to recover completely when adsorbed in the form of powder is solved.
Owner:SHANDONG ANALYSIS & TEST CENT
Method for preparing crosslinked chitosan microsphere heavy metal ion adsorbent
InactiveCN102614850AWide variety of sourcesLow priceOther chemical processesMicroballoon preparationCrosslinked chitosanDispersed media
The invention discloses a method for preparing a crosslinked chitosan microsphere heavy metal ion adsorbent. The method comprises the following steps of: 1) by taking chitosan as a material and liquid paraffin as an organic dispersing medium, protecting amino on chitosan C2 by using formaldehyde, and by taking epoxy chloropropane as a crosslinking agent, preparing a crosslinked chitosan microsphere by a reversed phase suspension crosslinking method; and 2) by taking the crosslinked chitosan microsphere as a matrix and 2-(chloromethyl)benzimidazole as a ligand, chemically grafting the crosslinked chitosan microsphere to obtain the crosslinked chitosan microsphere heavy metal ion adsorbent. The crosslinked chitosan microsphere heavy metal ion adsorbent prepared by the method has high adsorption speed, can selectively adsorb the Hg<2+> ion highly, can easily and completely desorb ions and can be repeatedly used.
Owner:ZHEJIANG GONGSHANG UNIVERSITY
Preparation method of compound emulsifier in-situ crosslinking chitosan quaternary ammonium salt essential oil microcapsule
ActiveCN105921085ASynchronizeSimple manufacturing processBiochemical fibre treatmentVegetal fibresCrosslinked chitosanCross-link
The invention discloses a preparation method of a compound emulsifier in-situ crosslinking chitosan quaternary ammonium salt essential oil microcapsule. A compound emulsifier which has the dual functions of an emulsifier and a cross-linking agent is prepared through double hydroformylation modification on polyethylene glycol; in the preparation process of the chitosan quaternary ammonium salt essential oil microcapsule, on one hand, essential oil is emulsified by a polyethylene glycol long carbon chain structure in the compound emulsifier, on the other hand, chitosan quaternary ammonium salt crosslinking is conducted through a condensation reaction between aldehyde groups at the two ends of the compound emulsifier and amino groups on the chitosan quaternary ammonium salt, and then synchronization of the essential oil emulsifying process and the chitosan quaternary ammonium salt crosslinking process is achieved. According to the preparation method, by grafting aldehyde molecules achieving the chitosan quaternary ammonium salt crosslinking function onto polyethylene glycol, freeing of micromolecular aldehyde in the essential oil microcapsule preparation process is avoided, therefore, the content of micromolecular aldehyde in the essential oil microcapsule product is decreased, and the toxicity of the product is lowered.
Owner:TIANJIN DOUBLE HORSE FLAVOR & FRAGRANCE NEW TECH
Method for preparing crosslinked chitin-glycan-quaterisation collagen hydrolysate
InactiveCN1640913AEasy and flexible productionStrong adhesionCrosslinked chitosanBiological dressing
The present invention is crosslinked chitosan-quaternized hydrolyzed collagen preparing process and relates to antibiotic biological material preparation. The crosslinked chitosan-quaternized hydrolyzed collagen is prepared with silkworm pupa chitin and hydrolyzed collagen as material. The preparation process includes mixing two kinds of solution, adding crosslinking agent to perform crosslinking reaction, membrane concentration, regulating pH value, and volumetric or spray drying to produce powder. The present invention can prepare solution or sol product and into the product, various water soluble functional factors, such as skin growth factor, moisture maintaining factor, vitamin, etc. may be added to form multifunctional biological dressing.
Owner:CHONGQING UNIV
Tannic acid cross-linked chitosan/gelatin liquid-absorbing hemostatic antibacterial sponge and preparation method thereof
ActiveCN112646228AImprove solubilityImprove mechanical propertiesSurgical adhesivesPharmaceutical delivery mechanismCrosslinked chitosanFreeze-drying
The invention belongs to the technical field of functional materials, and discloses tannic acid cross-linked chitosan gelatin liquid-absorbing hemostatic antibacterial sponge and a preparation method thereof. The preparation method comprises the steps: carrying out chemical cross-linking on chitosan and gelatin through an esterification reaction to form a primary cross-linking network, and thus obtaining modified super-hydrophilic gelatin; taking tannic acid as a cross-linking agent, and further cross-linking under the action of a strong oxidant to form a secondary cross-linked network; and then adding medical auxiliary materials, hydroxyapatite and sodium alginate to carry out physical mechanical foaming, and carrying out freeze drying to obtain the porous spongy chitosan / gelatin liquid-absorbing hemostatic antibacterial sponge. The spongy porous material obtained by crosslinking tannic acid with chitosan / gelatin is good in mechanical property, porous and fine in structure, soft in surface, wide in raw material source, low in market price, good in biocompatibility, non-toxic and biodegradable, and does not need to be infiltrated in advance when being in contact with a human body; and the preparation method is simple and efficient, is beneficial to large-scale production and has a good market application prospect.
Owner:JIAXING UNIV
High-strength antimicrobial dialdehyde starch crosslinked chitosan membane and preparation method and use thereof
InactiveCN1434072AGood mechanical strengthGood flexibilityPharmaceutical containersMedical packagingPliabilityChemistry
The present invention relates to a high-strength antimirobial dialdehyde starch cross-linked chitosan film, its production method and application. It is made up by using 1-3 wt% of chitosan acetic acid aqueos solution and 2-7 wt% of dialdehyde starch and adopting the processes of fully stirring, mixing, centrifugal defoaming, film-making, washing with acid, washing with water, drying by airing toobtain the invented product dried film. Said chitosan cross-linked film has excellent mechanical strength, flexibility and good antibacterial function, and has no toxic side effect for human body. Said chitosan cross-linked film has good bacteria-inhibiting action, can be used as clinical medical material for reducing infection of wound.
Owner:WUHAN UNIV
Method for preparing magnetic carbon nanotube/crosslinked chitosan composite nanomaterial adsorbent
InactiveCN102527346AImprove adsorption capacityImprove hydrophobicityOther chemical processesWaste water treatment from textile industryCrosslinked chitosanPtru catalyst
The invention relates to a method for preparing magnetic carbon nanotube / crosslinked chitosan composite nanomaterial adsorbent. According to the invention, a carbon nanotube original sample is adopted as a raw material; the magnetic performance of metal catalyst particles residual in the carbon nanotube original sample and the high-efficiency selective adsorption performance of the carbon nanotube are fully utilized; the adsorption performance of the material is significantly improved through compositing with biological material chitosan; therefore, the magnetic composite nanomaterial adsorbent with high efficiency in adsorbing dye in water phase is obtained. The magnetic composite nanomaterial adsorbent obtained in the invention has the advantages that: the carbon nanotube has no need to adopt strong acid treatment so that the structural integrity of the carbon nanotube is protected; the magnetic performance of the metal catalyst particles residual in the original sample is utilized so that additional process is not needed for composition of magnetic particles; moreover, the crosslinked chitosan has good biocompatibility to benefit the toxicity reduction of nanomaterial and potential biological application; and the obtained nano composite adsorbent can be conveniently and rapidly separated and recycled by adopting magnetic separation technology, so that secondary environmental pollution is avoided.
Owner:TONGJI UNIV
Porous magnetic chitosan gel microsphere with controllable particle size and preparation method thereof
PendingCN107282013AEasy to prepareReduce manufacturing costOther chemical processesWater contaminantsPeristaltic pumpStrong acids
The invention provides a porous magnetic chitosan gel microsphere with controllable particle size based on an in-situ co-precipitation principle and a preparation method thereof. The preparation method comprises the following main steps: firstly, carrying out a complexation reaction on a mixed solution of Fe<2+>, Fe<3+> and chitosan to prepare precursor-induced pre-sol; secondly, dropwise dripping the pre-sol into an alkaline soaking solution containing NaOH, sodium citrate and the like for coprecipitating to generate nano-Fe3O4; thirdly, carrying out a crosslinking reaction on the pre-sol and then curing, wherein the crosslinked chitosan gel microsphere is of a porous reticular structure and the Fe3O4 is uniformly distributed in the chitosan gel microsphere. The particle size of the chitosan gel microsphere is controlled by adjusting the rotating speed of a peristaltic pump and the concentration of the solution. The chitosan gel microsphere prepared by the method has the advantages of abundant pores, large specific surface area, and high adsorption and acid resistance; in addition, the preparation method has the characteristics of simplicity, wide source in raw materials, low cost, easiness in separation and recovery, no secondary pollution and the like. The porous magnetic chitosan gel microsphere disclosed by the invention can be used for enrichment, recovery and contamination remediation of metals in mines, smelting plants, electronic factories, electroplating plants and radioactive wastewater.
Owner:CHENGDU UNIVERSITY OF TECHNOLOGY +1
Preparation of water-soluble crosslinked chitosan and application thereof
The invention relates to preparation of water-soluble crosslinked chitosan and application thereof. The preparation comprises the following steps of: with different metal ions as templates, obtaining crosslinked chitosan through dialdehyde molecules by adopting a molecular imprinting technology; and hydriding Schiff base through sodium borohydride, and oxidizing and hydrolyzing by utilizing hydrogen peroxide to obtain the water-soluble crosslinked chitosan. The water-soluble crosslinked chitosan can be used for specifically adsorbing metal ions and applied to enrichment of metals, purification of metals bringing pollution to environment, emission acceleration of metals harmful to the human body as well as the injury treatment and emission acceleration of radionuclide.
Owner:GENERAL HOSPITAL OF THE SECOND ARTILLERY OF CHINESE PLA
Method of using dopamine for rapidly crosslinking chitosan to prepare hemostatic sponge
ActiveCN105343924AHigh mechanical strengthShorten the timeAbsorbent padsBandagesCrosslinked chitosanCross-link
Owner:深圳市和福汇生物科技有限公司
Method for preparing ultra-low pressure contamination-resistance composite reverse osmosis membrane using chitosan
InactiveCN101450289AImprove hydrophilicityImproves stain resistanceSemi-permeable membranesWater/sewage treatment bu osmosis/dialysisCrosslinked chitosanAcetic acid
The invention discloses a method for preparing an ultralow pressure fouling resistant composite reverse osmosis membrane through chitosan. The method comprises the following steps: dissolving chitosan with the deacetylation degree above 90 percent in acetic acid, and preparing solution A with the mass concentration of 1 to 10 percent after removing solid impurities in the solution; mixing crosslinking agent solution and hydrochloric acid through stirring to form solution B; and finally mixing solution A and solution B, spreading a mixed solution onto a polyamide carrier membrane, and preparing the ultralow pressure fouling resistant composite reverse osmosis membrane after drying. The obtained ultralow pressure fouling resistant composite reverse osmosis membrane has a crosslinked chitosan layer formed on a polyamide layer, thereby improving the hydrophilicity of the reverse osmosis membrane and the fouling resistance of the reverse osmosis membrane, and saving a great amount of power consumption during the operation with ultralow pressure.
Owner:TORAY FIBER RES INST(CHINA) CO LTD
Method for preparing epichlorohydrin crosslinked chitosan/aminated carbon nanotube composite aerogel
ActiveCN108745306AEvenly dispersedAvoid reunionOther chemical processesRadioactive contaminantsCrosslinked chitosanFreeze-drying
The invention relates to a method for preparing epichlorohydrin crosslinked chitosan / aminated carbon nanotube composite aerogel and specifically relates to a method for preparing composite aerogel bya freeze-drying method using chitosan and aminated carbon nanotubes as substrates and epichlorohydrin cross-linking and belongs to the field of functional materials. The aminated carbon nanotube can be used as a skeleton supporting material of the chitosan-based aerogel, effectively improves the mechanical strength of the chitosan-based composite aerogel and is easy to mold. The epichlorohydrin crosslinked chitosan / aminated carbon nanotube composite aerogel is lump and is easy to use and separate from water. The composite aerogel has a highly developed three-dimensional porous structure, goodmechanical strength and chemical stability, a U(VI) adsorption rate and adsorption capacity higher than those of the common resin and the highest adsorption capacity of 310 mg / g, realizes adsorption balance in 10min and is used for rapid and efficient separation and enrichment of uranium in uranium-containing wastewater.
Owner:EAST CHINA UNIV OF TECH
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