The invention relates to a branching polyamino
chitosan derivative and a preparation method thereof.
Hydrogen bond action of amino and hydroxy in
chitosan molecules causes poor swelling resistance property and poor dissolubility of the
chitosan, and the chitosan is only dissolved in a special
organic solvent, thus the application of the chitosan is limited. The preparation method comprises the steps of: dissolving chitosan in an
organic acid solution, dissolving
acrylate in lower
alcohol, mixing the
acrylate and the lower
alcohol and adding a proper of
tertiary amine, stirring for reacting for a certain time, regulating the pH, evaporating for removing water, separating out solids with
alcohol or
acetone, leaching, washing for several times, and
drying in vacuum to obtain N-carboxyethyl chitosan ester; adding the N-carboxyethyl chitosan ester and
polyamine in a flask, adding the alcohol and stirring for reacting, leaching, and washing for several times to obtain first-generation branching polyamino chitosan; and repeating the reaction to generate over
two generation super-branching chitosan. According to the invention, acetyl and the
polyamine are introduced in the chitosan amino, the
hydrogen bond of the chitosan is broken so that the derivative has water-
solubility, the amino content on the chitosan is effectively increased, and the application range of the chitosan is widened.