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196 results about "Aleuritic acid" patented technology

Aleuritic acid, or α-aleuritic acid, is a major ingredient in shellac, constituting about 35% of it. It is used as a starting material in the perfume industry for the preparation of musk aroma.

PEG-urate oxidase conjugates and use thereof

A naturally occurring or recombinant urate oxidase (uricase) covalently coupled to poly(ethylene glycol) or poly(ethylene oxide) (both referred to as PEG), wherein an average of 2 to 10 strands of PEG are conjugated to each uricase subunit and the PEG has an average molecular weight between about 5 kDa and 100 kDa. The resulting PEG-uricase conjugates are substantially non-immunogenic and retain at least 75% of the uricolytic activity of the unmodified enzyme.
Owner:HORIZON THERAPEUTICS USA INC +1

Lactic acid bacteria with effect of uric acid level reducing in blood

The present invention relates to lactic acid bacteria with an effect of uric acid level reducing in blood. According to the present invention, various lactic acid bacteria are cultured in the presence of a purine; a consumption amount of the purine and a production amount of purine decomposition products are determined; multiple lactic acid bacteria with significant purine decomposing abilities are selected; the selected lactic acid bacteria are adopted to orally feed rats, general statuses and serum uric acid levels of the rats are determined, and influence on the serum uric acid level due to the lactic acid bacteria feeding is researched, wherein the selected lactic acid bacteria are judged as the lactic acid bacteria having high purine decomposing abilities, and the rats are fed with a purine-containing feed; and two lactic acid bacteria capable of significantly inhibiting serum uric acid level increasing are found, wherein the two lactic acid bacteria are Lactobacillus gasseri OLL2959 and Lactobacillus oris OLL2779.
Owner:MEIJI CO LTD

Substitutional tea composition with uric acid reducing effect and preparation method thereof

The invention discloses substitutional tea with the uric acid reducing effect and a preparation method thereof. The substitutional tea is prepared from the following raw materials in parts by weight:10-60 parts of chicory, 40-110 parts of corn stigma, 20-100 parts of radix puerariae, 1-12 parts of rhizoma polygonati, 1-15 parts of poria cocos, 0.1-2 parts of celery seeds, 1-10 parts of emblic leafflower fruits, 300-500 parts of semen coicis, 0.5-3 parts of marine fish oligopeptide, 0.5-3 parts of seaweed extract, 0.5-3 parts of cherry powder, 30-80 parts of fructus momordicae grosvenori, 20-70 parts of fructus crataegi, 10-35 parts of horseradish tree leaves, 20-60 parts of cranberries and 20-80 parts of honeysuckle flower, wherein part of the raw materials are extracted and then granulated and are mixed and packaged with other raw materials so as to form the substitutional tea. The substitute tea with the uric acid reducing effect has the advantages that the raw materials such as leaves, rhizomes, flowers, fruits, seeds and functional factors of a food source are scientifically proportioned, aiming at different forming reasons of uric acid, adjuvant materials are not added, in addition, the use is convenient, the taste is good, the substitutional tea has no toxic and side effects after being drunk for a long time, is suitable for being drunk by people suffering from hyperuricemia for a long time and has very good uric acid reducing effect.
Owner:广州宏韵医药科技股份有限公司

Preparation method of ferrocenyl carbon nanotube composite material and application thereof

The invention discloses a preparation method of a ferrocenyl carbon nanotube composite material and application thereof and belongs to the technical field of synthesis of inorganic materials. The preparation method of the composite material comprises the following steps: firstly carrying out oxidization and amination on carbon nanotubes and carrying out acylation on ferrocenecarboxylic acid, then taking triethylamine as an acid-binding agent in a dichloromethane solvent, and enabling the carbon nanotubes subjected to amination to react with activated ferrocenylformyl chloride to prepare the composite material. The preparation method of the composit material is simple and is mild in reaction condition; the product is convenient to separate and purify and stable in structure. The composite material takes the carbon nanotubes with large specific surface area and high conductivity as support materials; ferrocenyl derivatives which can be used as electron media and provided with excellent electrochemical reversibility are covalently coupled on the surfaces of the carbon nanotubes, so that the composite material is excellent in effect of redox reaction for electrochemically catalyzing dopamine; the common interference matters including ascorbic acid and uric acid have no interference on detection of dopamine; the composite material is wide in linear response range and high in sensitivity and repeatability for detection of dopamine.
Owner:ANHUI UNIVERSITY OF TECHNOLOGY

Palladium nanoparticle/carbon nanofiber compound, preparation method and application thereof in electrocatalysis

The invention relates to a palladium nanoparticle/carbon nanofiber compound, a preparation method and an application thereof in electrocatalysis. The compound is directly prepared by a one-step electrospinning method. An electrode modified by the compound is used for direct eectrochemical detection on hydrogen peroxide, beta-nicotinamide adenine dinucleotide, dopamine, ascorbic acid and lithic acid. The electrode modified by the compound has the linear range from 0.2 micrometer to 20 millimetres and the detection limit of 0.2 micrometer when being used for the detection on the hydrogen peroxide and has the linear range of 0.2-716.6 micrometers and the detection limit of 0.2 micrometer when being used for the detection on the beta- nicotinamide adenine dinucleotide; and the peak-peak potential differences between the ascorbic acid and the dopamine, the dopamine and the lithic acid as well as the ascorbic acid and the lithic acid are respectively 244mV, 148 mV and 392 mV, thereby showingthat the modified electrode can be used for simultaneous eectrochemical detection of three substances. The compound can be used in the fields of catalysis, fuel cells and sensing.
Owner:CHANGZHOU INST OF ENERGY STORAGE MATERIALS &DEVICES

Konjac-flour-containing mixture and preparation method thereof

The invention discloses a konjac flour-containing mixture and a preparation method thereof. The konjac flour-containing mixture is prepared from the following components in percentage by weight: 20-40% of konjac flour, 10-20% of celery powder, 2-8% of hawthorn fruit powder and 40-60% of giant salamander powder. The preparation method comprises the following steps: sequentially carrying out quick-freezing, drying and crushing on celeries, and grinding into ultra micro fine powder with a size of more than 200 meshes; processing and crushing hawthorn fruits by using the conventional drug preparation method, and grinding into ultra micro fine powder with a size of more than 200 meshes; defatting living giant salamanders, removing the lungs and intestinal canals of the living giant salamanders, carrying out vacuum freeze-drying, and crushing and grinding into nano fine powder; and finally, mixing the three kinds of powder with konjac fine flour sold in the market according to the ratio above so as to obtain the konjac flour-containing mixture which is a nutrient health-care product. The konjac flour-containing mixture disclosed by the invention has the effects of tonifying the spleen, promoting appetite, relaxing the bowels, losing weight, reducing blood fat and blood sugar, neutralizing uric acid and the like. The preparation method preserves various nutrient components. The commodity type mixture is convenient to eat, and easy to enable people to eat frequently and continuously.
Owner:汉中天成生物工程有限公司

Saury Maillard peptide with uric acid reducing activity as well as preparation method and application thereof

The invention discloses a saury Maillard peptide with uric acid reducing activity as well as a preparation method and an application thereof. The preparation method comprises steps as follows: mincing saury, adding water, heating and stirring the mixture, adjusting the pH value to 4.2, performing centrifugal separation, and taking a precipitate; adding water, protease and monomer amino acid to the precipitate, adjusting the pH value to 7.0, adding reducing sugar after hydrolysis for a reaction, performing centrifugation, and taking a supernatant, that is, a saury Maillard peptide liquid; performing spray drying on the peptide liquid to obtain dried saury Maillard peptide powder. With the adoption of the method, the Maillard peptide is prepared under the continuous action of enzymolysis and a Maillard reaction, the production technology process is simplified, the production cycle is shortened, the production cost is reduced, the uric acid reducing effect of the prepared target Maillard peptide is significant, and rat animal experiments indicate that the uric-acid-reducing Maillard peptide prepared with the method can significantly reduce the blood uric acid level of rats and has a certain protection effect on kidney functions of the rats.
Owner:GUANGDONG SINOPEPTIDE BIOTECHNOLOGY CO LTD

Composition containing dipeptide of histidine and alanine for reducing uric acid and method for reducing uric acid using the dipeptide

InactiveUS20070099846A1Useful in treatmentReducing uric acidNervous disorderDipeptide ingredientsUA - Uric acidDipeptide
The present invention relates to a composition comprising an effective amount or an effective amount of one or more dipeptides consisting of histidine or the functional equivalent thereof and alanine or the functional equivalent thereof for reducing uric acid in a subject. The invention also provides a method for the treatment of gout or the amelioration of symptoms related to a high level of uric acid comprising the step of administering or applying the above-mentioned dipeptides to a subject.
Owner:LYTONE ENTERPRISE INC

Preparation method and application of nano-porous gold/carbon fiber paper composite sensing electrode allowing uric acid and dopamine to be detected simultaneously

The invention provides a preparation method of a nano-porous gold / carbon fiber paper composite sensing electrode (NPG / Ni / CFP) and application of the electrode to electrochemical detection of uric acidand dopamine under the condition that ascorbic acid exits. The preparation method comprises the steps that thin-layer metallic nickel is pre-deposited on carbon fiber paper (CFP) to obtain an Ni / CFPcomposite electrode, then a gold-tin alloy thin film is electro-deposited to obtain an AuSn / Ni / CFP composite electrode, then the AuSn / Ni / CFP composite electrode is placed in an alkaline corrosive liquid to be subjected to dealloying completely, and the composite electrode NPG / Ni / CFP is obtained. The preparation method has the advantages of being simple in preparation technology, low in cost, easyand convenient to use, good in stability and the like; and the composite electrode has high selectivity, high stability and anti-interference capability, can be used for determining the uric acid andthe dopamine separately or simultaneously and has a low detection limit and high sensitivity.
Owner:广州钰芯传感科技有限公司

Adhesive for cigarettes

The invention discloses an adhesive for cigarettes. The adhesive is prepared from the following components in parts by weight: 30-40 parts of cassava starch, 30-40 parts of carboxymethyl starch, 5-10 parts of isocyanate, 2-5 parts of sodium trimetaphosphate, 0.1-0.5 part of uric acid, 10-30 parts of polyvinyl alcohol, 10-15 parts of bentonite, 0.1-0.5 part of sodium dodecyl sulfate and 150-200 parts of water. The invention also provides a preparation method for the adhesive for the cigarettes. The adhesive for the cigarettes is a cigarette adhesive prepared by oxidation, cross linking and polyvinyl alcohol modification of the starch, each performance of the adhesive accords with the index of the cigarette adhesive, and the adhesive has good performance and has the characteristics of corrosion resistance, low cost, no harm to a human body, simple process and the like.
Owner:陆青

Celery seed extract, preparation and preparation method thereof

The present invention relates to a celery seed extract, a preparation and a preparation method thereof. The preparation method comprises: taking dried celery seeds, and carrying out reflux extraction 1-2 times with 2-4 times the volume of an ethanol aqueous solution with a volume fraction of 95%; collecting the extraction liquids, and carrying out pressure reducing concentration to obtain a thick extract; suspending the thick extract in water having the volume 0.5-1 time the volume of the raw material, extracting 2-4 times with an extraction reagent, and combining the organic phases after completing the extracting to obtain a crude extract; weighing silica gel having the mass of 35-55 times the mass of the crude extract, activating for 1 h at a temperature of 130 DEG C, and loading into a chromatography column; taking the crude extract, and injecting in a concentration of 0.2-0.5 g / ml; and carrying out gradient elution with petroleum ether-dichloromethane-ethyl acetate, collecting the flow, and carrying out pressure reducing concentration to obtain the celery seed extract. According to the present invention, the preparation method has characteristics of simple preparation process, less extraction number, and high yield; and the obtained celery seed extract has the good serum uric acid lowering effect.
Owner:赛隆药业集团股份有限公司

Uric acid reducing composition and preparation thereof

The invention relates to the technical field of health products, and especially relates to a uric acid reducing composition and a preparation thereof. The uric acid reducing composition comprises skipjack tuna extract and dietary fibers. The skipjack tuna extract and the dietary fibers are combined and then used, so the dosage is reduced, and the uric acid reducing effect is good.
Owner:BY HEALTH CO LTD

Uric acid electrochemical sensor based on active copper carbon point and application thereof

The invention discloses a uric acid electrochemical sensor based on an active copper carbon point and an application thereof. The application comprises the following steps: adding a high molecular polymer rich in carboxyl and cupric salt into a reaction container, putting the reaction container in a hydrothermal reaction kettle, performing a reaction for 2-18h at 200-240 DEG C, performing centrifugalization and dialysis and purification to obtain an active copper carbon dot-containing solution; by adopting a three-electrode system, taking a glass carbon electrode as a working electrode, a platinum wire electrode as a counter electrode and a saturated mercurous chloride electrode as a reference electrode, putting the pre-treated glass carbon electrode in the active copper carbon dot-containing solution, and performing scan round at the scanning speed of 50-500mV/s in a potential range of 0-2V by means of an electrodeposition method. Compared with the prior art, the nanomaterial containing the active copper carbon dots not only has a large specific surface area of the carbon dots and a high electron transmission rate, but also a promoting action on the electron transfer rate on a matrix on an electrode interface by active copper and very strong selectivity on uric acid.
Owner:艾科思电子科技(常州)有限公司

Preparation method of meteng fruit meal bioactive peptide with uric acid reducing effect

The invention discloses a preparation method of a meteng fruit meal bioactivity peptide with a uric acid reducing effect, which comprises the following steps:(1) pretreatment of meteng seed meal: crushing, degreasing, removing an organic reagent, and soaking in water to obtain a meteng seed meal solution;(2) protease enzymolysis: heating to 40-60 DEG C, adjusting pH to 2-11, adding protease for hydrolysis, then inactivating enzyme at high temperature, centrifuging, and taking supernatant to obtain crude enzymolysis solution;(3) fermentation of bacillus lactis DU-106: inoculating the fermentation seed solution to the crude enzymolysis solution of maitenu protein, stirring and mixing uniformly, and fermenting at 25-35 DEG C for 2-7 days;(4) neutralization and filteration: adjusting the pH value of the cooled hydrolysate to be neutral, and filtering to obtain enzymolysis solution; (5) membrane separation: carrying out ultrafiltration membrane filtration, evaporation concentration and freeze drying. According to the invention, protease enzymolysis, lactic acid bacillus DU-106 fermentation and ultrafiltration separation technologies are utilized to prepare the meteng fruit meal bioactive peptide, so that the meteng fruit meal bioactive peptide has an obvious uric acid reducing effect; and the meteng fruit meal is leftovers generated after the meteng fruit is pressed into oil, so that the method has the advantages of simple process, low production cost and no pollution.
Owner:SOUTH CHINA AGRI UNIV
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