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Application of sunflower disc hydrolysis compound powder in preparing of medicine for curing or relieving high uric acid gout

A composite powder and sunflower disk technology, applied in the field of biomedicine, can solve the problems of non-absorption absorption efficiency, large molecular weight of plant protein, etc.

Active Publication Date: 2015-12-09
JILIN PROVINCE TEYIFOOD BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the sunflower dish contains a large amount of plant protein that is beneficial to human health. However, due to the large molecular weight of plant protein, most of the plant protein is not absorbed or the absorption efficiency is extremely low after entering the human body.

Method used

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  • Application of sunflower disc hydrolysis compound powder in preparing of medicine for curing or relieving high uric acid gout
  • Application of sunflower disc hydrolysis compound powder in preparing of medicine for curing or relieving high uric acid gout
  • Application of sunflower disc hydrolysis compound powder in preparing of medicine for curing or relieving high uric acid gout

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1: Establishment of a model of hyperuricemia in rats.

[0035] 【experiment procedure】:

[0036] (1) Order rats: Wistar male rats were ordered from Y-S Experimental Animal Company in Changchun City, Jilin Province and raised in a laboratory environment for one week to adapt to the experimental environment.

[0037] (2) Preparation before modeling: After adapting to the experimental environment for one week, the rats were weighed and randomly divided into a control group (10 rats), a modeling group I (15 rats) and a modeling II group (15 rats).

[0038] (3) About 300 μL of blood was taken from the orbit of each rat with a capillary glass tube. The blood sample was placed at 30°C for 30 minutes and then centrifuged at 10,000 g for 30 minutes. .

[0039] (4) Establish hyperuricemia model: intragastric administration once a day according to rat body weight, (control group: intragastric administration of drinking water; modeling group I and II intragastric administr...

Embodiment 2

[0042] Example 2: Detection of the preventive effect of sunflower disc hydrolyzed composite powder (SfPP) on hyperuricemia in rats.

[0043] 【experiment procedure】:

[0044] (1) Order rats: Wistar male rats were ordered from Y-S Experimental Animal Company in Changchun City, Jilin Province and raised in a laboratory environment for one week to adapt to the experimental environment.

[0045] (2) Preparation before modeling: After adapting to the experimental environment for 1 week, the rats were weighed and randomly divided into blank control group (10 rats), modeling group (15 rats) and modeling agent + SfPP group (15 rats).

[0046] (3) About 300 μL of blood was taken from the orbit of each rat with a capillary glass tube. The blood sample was placed at 30°C for 30 minutes and then centrifuged at 10,000 g for 30 minutes. .

[0047] (4) Preventive treatment detection of SfPP: gavage once a day according to rat body weight, (control group: gavage drinking water; modeling grou...

Embodiment 3

[0050] Example 3: Detection of the therapeutic effect of sunflower disc hydrolyzed composite powder (SfPP) on hyperuricemia in rats.

[0051] 【experiment procedure】:

[0052] (1) Order rats: Wistar male rats were ordered from Y-S Experimental Animal Company in Changchun City, Jilin Province and raised in a laboratory environment for one week to adapt to the experimental environment.

[0053] (2) Preparation before modeling: After adapting to the experimental environment for 1 week, the rats were weighed and randomly divided into blank control group (10 rats), modeling group (15 rats) and modeling agent + SfPP group (15 rats).

[0054] (3) About 300 μL of blood was taken from the orbit of each rat with a capillary glass tube. The blood sample was placed at 30°C for 30 minutes and then centrifuged at 10,000 g for 30 minutes. .

[0055] (4) Detection of the therapeutic effect of SfPP on hyperuricemia in rats: intragastric administration once a day according to rat body weight, ...

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Abstract

Application of sunflower disc hydrolysis compound powder in preparing of food, medicine or food and medicine composition for preventing, curing or relieving blood uric acid rising-related diseases belongs to the technical field of biological medicine. According to the sunflower disc hydrolysis compound powder, by a method of hydrolyzing a soak solution of a sunflower disc with enzyme, on the basis of not damaging original components of the sunflower disc as much as possible, plant large molecules in the sunflower disc are hydrolyzed into micro-molecule polypeptide. It is found for the first time in research that the sunflower disc hydrolysis compound powder has an action of preventing rising of blood uric acid in animals, and also has a potential action of reducing high uric acid formed in blood. Therefore, the sunflower disc hydrolysis compound powder should be applied in preparing of food, medicine or food and medicine composition for relieving or curing gout.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and specifically relates to the application of sunflower dish hydrolyzed composite powder in the preparation of food, medicine or food and pharmaceutical composition for preventing, alleviating or treating diseases related to elevated blood uric acid levels. Background technique [0002] Gout is a chronic metabolic disorder. Its main feature is excessive production of uric acid in the body or decreased excretion of uric acid by the kidneys, which causes the concentration of urate in the blood to increase, so it is also called hyperuricemia. At present, it is believed that the cause of hyperuricemia is mainly due to eating too much high-purine food (such as animal offal, seafood, chicken, duck, goose, quail, pigeon, etc.). Uric acid is a metabolite of purine. Therefore, long-term excessive intake of high-purine food, once the excretion capacity of the body is exceeded, will gradually accumulat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61K38/00A61P19/06A23L1/29A23L33/00
Inventor 蔡勇金景姬赵佳瑶沈双王飞刘达赵林红赵桐
Owner JILIN PROVINCE TEYIFOOD BIOTECH CO LTD
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