The invention discloses a manufacturing method of a mullite-boron nitride composite ceramic side sealing plate for thin-strip continuous casting. The manufacturing method comprises the following steps: (1) preparing precursor slurry, namely mixing hexagonal boron nitride powder, silicon dioxide powder and aluminum nitrate powder, then adding a slurry preparing solvent to prepare slurry, fully mixing the slurry uniformly, standing for a certain period of time, and finally washing and filtering the slurry by using distilled water of 100-130 DEG C to obtain a filter residue namely the precursor slurry; (2) preparing a mixed batch, namely mixing the precursor slurry, silicon nitride powder, aluminum nitride powder, titanium boride powder and diboron trioxide to prepare the mixed batch; (3) pretreating the mixed batch; and (4) performing hot pressed sintering. The side sealing plate prepared by the method disclosed by the invention is very high in strength, compactness and breaking strength, low in thermal conductivity and good in thermal shock resistance, so that the service life of the side sealing plate is prolonged, and the problem of continuous casting interruption is avoided; and moreover, the use stability of the ceramic side sealing plate is improved, the production cost of thin-strip continuous casting is reduced, and considerable economic benefits are achieved.