The invention relates to a manufacturing process of an inner liner with an oval seal head, which comprises the following steps: S1, manufacturing an inner liner cover, which includes S11, marking theinner surface of the seal head into N equal parts, S12, drawing an outer edge trace line of the inner liner cover on the inner surface of the seal head, S13, measuring the arc size and the width sideL of the marked dividing area, S14, making one piece of watermelon petal inner liner cover sample, S15, making the remaining N-1 piece of watermelon petals inner liner cover samples, and S16, assemblywelding N pieces equal divided watermelon petal inner liner cover samples; S2, manufacturing an inner liner cone; S3, manufacturing an inner liner cylinder body and S4, assembling an oval seal head inner liner. The manufacturing process of the inner liner with an oval seal head adopts the rolling and forming of the plate bending machine, is not limited by the size of the diameter of the seal head, is convenient to manufacture, accelerates the construction period, saves the cost and has high assembly precision; the inner liner of the oval seal head has an anti-wear effect on a pressure container, and effectively prolongs the service life of the pressure container.