The invention relates to a traditional Chinese medicine anti-wrinkle handmade soap, which can effectively solve the problems that industrially manufactured anti-wrinkle products not only can not effectively resist wrinkles, but also easily injure skin, and cause allergy. The adopted technical scheme includes that the anti-wrinkle handmade soap is made of raw materials by weight percent: 5-8% of rice bran oil, 10-15% of camellia oil, 10-15% of sweet almond oil, 5-8% of grape seed oil, 8-12% of coconut oil, 8-12% of palm oil, 8-12% of olive oil, 8-12% of sodium hydroxide, 15-20% of pure water, 1-3% of vitamin E, 0.5-1% of eucommia extract, 0.5-1% of extract of angelica sinensis, 0.5-1% of extract of herba leonuri, 0.5-1% of extract of papermulberry fruit, 0.5-1% of extract of rosa rugose and 0-3% of auxiliary material. The traditional Chinese medicine anti-wrinkle handmade soap is flexible in formula, can increase and decrease oil content according to skin types, and also can add the auxiliary material according to needs. The traditional Chinese medicine anti-wrinkle handmade soap is a pure natural product, can not injure the skin, is applicable to people of allergic constitution, and is an innovation of handmade soaps.