The invention discloses a synthetic high-temperature lubricating grease and a production method thereof. The synthetic high-temperature lubricating grease is produced by taking synthetic oil as base oil and mixing the base oil with thickening agents, an extreme-pressure additive, an antioxidant and an anticorrosive agent, wherein the weight ratios of all ingredients are as follows: 47-94% of base oil, 2-20% of polyurea thickening agent, 2-20% of acylamide thickening agent, 0.5-5.0% of antioxidant, 1.0-5.0% of extreme-pressure additive and 0.5-3.0% of anticorrosive agent. In the invention, the synthetic base oil, the polyurea thickening agent and the acylamide thickening agent all have excellent high-temperature performance, and the organic combination thereof leads the lubricating grease to obtain excellent high-temperature performance; the polyurea thickening agent endows the lubricating grease with good colloid stability, and the acylamide thickening agent endows the lubricating grease with excellent anti-shear stability, therefore, the organic combination of colloid stability and anti-shear stability leads the lubricating grease to have excellent high-temperature performance and good losing resistance, does not change to thin and avoids losing at high temperature. The extreme-pressure anti-wear additive endows the lubricating grease with excellent extreme-pressure anti-wear performance, and the bearing capacity is high.