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60results about How to "Dose controllable" patented technology

Voriconazole injection and its preparing method

The present invention relates to a fuliconazole injection. Said injection includes the following components; (by wt%) fuliconazole 0.01-20%, cyclodextrin or cyclodextrin derivative 0%-60%, water-soluble excipient 0-75%, solubilizer 0%-20% and the rest is injection water. Its preparation method includes the following steps: mixing the above-mentioned raw materials, using active carbon to remove impurity and heat source, filtering, fine filtering, filling, sterilizing, checking and putting in storage.
Owner:南京都药医药科技有限公司

Cleaning cocoon cooking method

InactiveCN103225112ANo emissionsThe total amount is controllableSilk filament obtainingChemical preparationDissolution
The invention discloses a cleaning cocoon cooking method. The method comprises the processes of: external vacuum infiltration, cooking by an automatic cooker, cocoon steaming, and adjustment, wherein a reelability agent originally used for cocoon cooking replaces a penetrating agent for penetrating to be used in the external vacuum infiltration cocoon cooking process; in the condition with 30-50 DEG C water temperature, the reelability agent can only have infiltration function with water to be adsorbed between cocoon layers and on the surface of a cocoon filament; and in the cocoon cooking process and in the condition with 60-80 DEG C water temperature, the reelability agent can promote the cocoon filament sericin dissolution to reduce adhesion between cocoon filaments for the smooth dissociation of the cocoon filaments, so that the reelability agent has the reelability function in the cocoon cooking process. One chemical preparation achieves two functions, the chemical preparation is less and easily controlled in dose, process is simple, operation is convenient, and production cost is low.
Owner:安徽绩溪县花神丝绸有限公司

Water treatment agent prepared by blast furnace slag and preparation method thereof

The invention relates to a water treatment agent prepared by utilizing blast furnace slag, and the agent is obtained by treating blast furnace slag by alkaline solution. The blast furnace slag comprises: 25-30% of SiO2, 40-45% of CaO, 15-20% of Al2O3, 10-20% of MgO, 1.08-1.5 of (CaO+MgO) / (Al2O3+SiO2). The alkaline solution with pH of more than 11 are mixed with the blast furnace slag as per 1 : 1-5 of the solid-to-liquid ratio, dried for 24-48h at 50-120 DEG C after filtration, and the outcome is taken out, smashed and passes through a standard filter of 6-80 m. The improved blast furnace slag is used as the water treatment agent and can treat the sewage with high efficiency and large amount, especially for the sewage containing the ions such as Ni(II), Pb (II), Cu(II), Zn(II), Mn(II), Fe(III), Al(III), Cr(III), etc.
Owner:INST OF PROCESS ENG CHINESE ACAD OF SCI

Halloysite nanotube drug sustained-release material and preparation method thereof

The invention relates to a halloysite nanotube drug sustained-release material and a preparation method thereof. The drug sustained-release material is prepared by the following steps: performing acid corrosion to a halloysite nanotube to obtain a dilated nanotube, loading the drug into an inner cavity of the halloysite nanotube, and coating an organosilane polymerized hydrophobic layer onto the surface of the drug-carried halloysite nanotube, wherein the during the coating of the organosilane polymerized hydrophobic layer, organosilane I is firstly used for modifying the outer surface of the halloysite nanotube, and then organosilane II is added to form the organosilane polymerized hydrophobic layer on the surface of the nanotube. Compared with the prior art, the sustained release material has universality on a hydrophobic drug and a hydrophile drug, the drug release time can be effectively prolonged, the encapsulation efficiency is high, and the administration safety of the drug can be improved.
Owner:CENT SOUTH UNIV

Automatic Chinese medicine acquisition device

The invention discloses an automatic Chinese medicine acquisition device. The automatic Chinese medicine acquisition device comprises a mounting support, a Chinese medicine storage case fixed on the support, a Chinese medicine outlet mechanism which is mounted on the support and is arranged below the Chinese medicine storage case to receive Chinese medicine falling from a Chinese medicine outlet, a Chinese medicine feeding mechanism which is mounted on the support, is used for receiving the Chinese medicine from the Chinese medicine outlet mechanism and outputting the received Chinese medicine and comprises a weighing unit used for weighing the received Chinese medicine, and a control system used for controlling Chinese medicine amount of the Chinese medicine outlet mechanism according to the weighing result of the weighing unit to acquire Chinese medicine at predetermined amount, wherein a bottom portion of the Chinese medicine storage case is provided with the Chinese medicine outlet. The automatic Chinese medicine acquisition device is advantaged in that automatic efficient Chinese medicine quantification is realized, processing efficiency of Chinese medicine prescriptions and Chinese medicine material acquisition precision are improved, and thereby artificial labor intensity is reduced.
Owner:杭州东程科技有限公司

Flourishing controlling and production increasing medicament composition and application thereof

The invention belongs to the technical field of plant growth regulators, and relates to a medicament composition being capable of controlling flourishing of plants and having a production increasing effect and application of the medicament composition. A plant growth regulator composition provided by the invention comprises the active ingredients of prohexadione calcium, paclobutrazol and a plant growth promoter, wherein the plant growth promoter is compound sodium nitrophenolate, diethyl aminoethyl hexanoate or gibberellin. 25% prohexadione calcium and paclobutrazol composite medicament wettable powder is used for controlling the flourishing of crops, and has the best effect when the dosage is 20g / acreage when being particularly used for controlling the flourishing of peanuts, soybeans or rapes. The plant growth regulator composition disclosed by the invention belongs to a ternary complex product, and compared with singly using prohexadione calcium to adjust the growth of the crops, the cost is greatly reduced, the dosage is easy to control, and the production increase of the crops is obvious; the safety is much higher than that of singly using paclobutrazol; compared with other triazole plant growth regulators for retarding plant growth, the plant growth regulator composition has the advantages of low residual toxicity, less dosage and environmental friendliness.
Owner:郑州郑氏化工产品有限公司

Ibuprofen injection and preparation method thereof

The invention relates to ibuprofen injection and a preparation method thereof. The ibuprofen injection comprises 0.5 to 20 weight percent of ibuprofen, 10 to 60 weight percent of cyclodextrin or cyclodextrin derivatives, 1 to 40 weight percent of water soluble excipient and the balance of water, wherein ibuprofen serves as a main medicament; and the cyclodextrin or cyclodextrin derivatives and the water soluble excipient serve as medicinal auxiliary materials. In the invention, the cyclodextrin or cyclodextrin derivatives represented by hydroxypropyl-beta-cyclodextrin is used to make the ibuprofen, which used to be water insoluble, very water soluble. The stability of the medicament is improved. The clathrate compounds can be made into injection using water as a solvent or power for injection. Thus, it is very convenient to administrate the medicament in clinic and it is easy to control injection volume. Meanwhile, the drawback of the universal adoption of auxiliary materials and solvents for injection, which are very dangerous, such as organic solvents and cosolvents, of the conventional insoluble and soluble medicinal injection is overcome.
Owner:HANGZHOU SHARPLY PHARM R&D INSTIT +2

Means for taking-care of anus and intestine

An anorectal canal nursing device is composed of connecting tube, the air bag unit consisting of upper and lower air bags, air tube, air valve connected via air tube with said air bag unit, delivering tube, and dirt storage bag.
Owner:高静静

Green (no pollution) instant, concentrated tremella powder, prepn. method and application thereof

An instant powder of concentrated tremella is prepared from tremella through dewatering by heating at 40-50 deg.C for 2-3 hr, at 50-60 deg.C for 2-3 hr, and at 80-90 deg.C for 4-6 hr, microwave sterilizing at 120-150 deg.C for 50-60 min and grinding by 150-350 meshes. Its application is also disclosed.
Owner:余新邦

Diacerein injection type thermo-sensitive gel and method for preparing same

The invention provides diacerein injection type thermo-sensitive gel. The diacerein injection type thermo-sensitive gel comprises diacerein, poloxamer 407, poloxamer 188 and HPMC (hydroxypropyl methylcelluloses). A concentration ratio (w / v) of the diacerein to the P-407 to the P-188 to the HPMC is 0.5%:17-22%:1-5%:0.3-1.0%. A method for preparing the diacerein injection type thermo-sensitive gelincludes preparation steps of swelling the HPMC by the aid of water at the room temperature to obtain HPMC solution; uniformly scattering the poloxamer P-407 and the poloxamer P-188 on the surface ofthe HPMC solution and carrying out overnight swelling and dissolving to obtain blank thermo-sensitive gel solution; sufficiently dissolving the diacerein by the aid of DMSO (dimethyl sulfoxide) to obtain diacerein solution and then adding the diacerein solution into the blank thermo-sensitive gel solution to obtain diacerein thermo-sensitive gel solution. The diacerein injection type thermo-sensitive gel and the method have the advantages that the diacerein injection type thermo-sensitive gel prepared by the aid of the method is prepared from water-soluble high-polymer materials, is excellentin histocompatibility and bio-adhesion, is long in detention time at medication positions, can be slowly released and is long-acting, and the purpose of reducing side effects on gastrointestinal tracts can be achieved.
Owner:GUANGDONG PHARMA UNIV

Salvia miltiorrhiza and red flower dropping pill and preparation method thereof

The invention belongs to the technical field of health care food and discloses a salvia miltiorrhiza and red flower dropping pill and a preparation method thereof. The salvia miltiorrhiza and red flower dropping pill is characterized in that the dropping pill consists of active ingredients of extracts obtained through extracting salvia miltiorrhiza and red flower according to a weight part ratio being 3:(1-1.5), and the weight part ratio of dripping pill active ingredients to substrates is 1:(3-5). Tests prove that the dropping pill provided by the invention has a good health care effect and is superior to the similar products.
Owner:张睿

Sang-Fu-Teh acupoint pasting film

The invention relates to a traditional Chinese medical instrumentation, in particular to a Sang-Fu-Teh acupoint pasting film which is simply and conveniently used. In the invention, different traditional Chinese medical ointment can be selected according to diseases to be treated and then applied to a drug storage tank of the pasting film so as to facilitate medical personnel to carry out acupoint application for treating the diseases. The Sang-Fu-Teh acupoint pasting film can facilitate drug replacement in acupoint application, improve working efficiency of Sang-Fu-Teh plaster, reduce working strength and working load of the medical personnel and shorten waiting time of a patient. The Sang-Fu-Teh acupoint pasting film is composed of medical rubber adhesive plaster, the drug storage tank and a covering film; and only the traditional Chinese medical ointment is added to the drug storage tank when in use and then applied to a corresponding acupoint. The Sang-Fu-The acupoint pasting film is used in a Sang-Fu-Teh therapy of the traditional Chinese medical characteristic therapy 'winter disease being cured in summer' and the traditional Chinese medical external therapy such as the Sang-Fu-Teh therapy, common acupoint application and the like. The Sang-Giu-Teh acupoint pasting film has the advantages of convenient use, being safe and reliable, saved time of an operator, low manufacturing cost and easy popularization and application.
Owner:张华

Soybean whey protein composite powder and preparation method thereof

The invention relates to soybean whey protein composite powder and a preparation method thereof. The soybean whey protein composite powder comprises, by weight, 5-10 parts of soy isolate protein powder, 12-20 parts of whey protein concentrate powder, 3-10 parts of fish collagen protein powder and 0.5-2 parts of taurine. In preparation, the soy isolate protein powder, whey protein concentrate powder and fish collagen protein powder are mixed according to the weight part ratio, other components are added into the mixture through a fluidized bed, the mixture is subjected to granulation, and the product is collected and is sterilized so that a finished product is obtained. Compared with the prior art, the preparation method utilizes soy isolate protein powder, whey protein concentrate powder and fish collagen protein powder as main raw material and uses taurine, coix seed powder, poria cocos powder, soya bean lecithin and soybean oligosaccharides so that the soybean whey protein composite powder is rich in comprehensive and balanced nutrients, has high protein content, is pure natural, does not produce pollution, does not contain a preservative, contains multiple natural active components, has low cholesterol content, low fat content and low heat and fast supplies comprehensive nutrients.
Owner:SHANGHAI SPRING TANG BIO PROD

Method for constructing pepper mutant library from ethylmethane sulfonate

PendingCN108617502AImprove anti-aphid performanceHigh yieldPlant genotype modificationGenomicsEthylmethane Sulfonate
The invention discloses a method for constructing a pepper mutant library from ethylmethane sulfonate. The method is characterized in that a Zunla 1 is used as a mutagenesis object; on the premise ofpointing out the influence of treating fluid dose and excluding space of each seed on germination percentage, semi-lethal dose is determined by comparing the germination percentage of pepper seeds with EMS treating fluid with different concentrations at different mutagenesis time; the pepper seeds are treated by mutagenesis of the semi-lethal dose; mutation frequency and mutation types of M2 generation are investigated, a mutant capable of stably inheriting of M4 generation is identified and a mutant library is constructed; the mutation types of leaves, stems, fruits, growth period, flower organs, fertility and the like are obtained and create abundant materials for functional genomics reach of pepper; and meanwhile, partial beneficial mutation can be directly applied to breeding practice.
Owner:GUIZHOU SERICULTURE RES INST GUIZHOU PEPPER RES INST

Potato seed coating agent

The invention discloses a potato seed coating agent, which mainly comprises the following active ingredients in percentage by weight: 0.8 to 2.2 percent of compound sodium nitrophenolate serving as a plant growth regulator, 0.2 to 1.6 percent of raw alpha-sodium acetate serving as another plant growth regulator, and the balance of synergic aid and solvent which are allowed to be used in pesticideand can be accepted. Seeds are soaked and dressed, and a protective agent membrane is formed around the tomatoes so that the potato seed coating agent can prevent insects and diseases in the whole growth process of the potatoes, improve soil, fulfill the purposes of increasing the yield and improving the quality, and effectively relieve several contradictions that the plant diseases and insect pests have medicinal resistance on insecticide and germicide and the potatoes are not suitable for long-term storage after the fertilizer is applied and the yield is increased.
Owner:常华

Oral cavity external preparation and preparation method thereof

The invention discloses an oral cavity external preparation. The preparation is a composite film composed of a back bottom layer, a slow-release layer and a quick-release layer. The back bottom layer is a film prepared from ethyl cellulose. The slow-release layer is a film prepared from mixed glue formed by mixing traditional Chinese medicine extracts, porous starch, chitosan, sodium alginate, polyving acohol, borneol, honey and purified water according to a certain mass ratio. The quick-release layer is a film prepared from mixed glue formed by mixing traditional Chinese medicine extracts, porous starch, borax, carbomer, peppermint oil and purified water according to a mass ratio. Meanwhile, the invention further discloses a preparation method of the preparation. By means of the unique formula of the traditional Chinese medicine extracts and scientific design of the dosage form film layers, troubles of existing oral cavity preparations are effectively solved, and the oral cavity external preparation takes effect quickly, is good in slow-release performance, has the effects of relieving swelling and pain and dispersing blood stasis and dredging collaterals and has the unique treatment effect of treating both symptoms and causes of periodontal diseases.
Owner:中国人民解放军白求恩医务士官学校

Method for production of granular calcium dihydrogen phosphate by one-time granulation of concentrated phosphoric acid

Relating to the technical field of production of feed grade calcium dihydrogen phosphate, the invention discloses a method for production of feed grade granular calcium dihydrogen phosphate from wet-process defluorinated concentrated phosphoric acid. The method includes the steps of: S1: subjecting concentrated phosphoric acid with a phosphorus pentoxide content of 45-55wt% and a calcium carbonateemulsion to mixed reaction in a reactor to produce a mixed slurry containing calcium dihydrogen phosphate, wherein the calcium carbonate emulsion and concentrated phosphoric acid are proportioned according to a Ca / P ratio of 0.58-0.68, the reaction temperature is 60-80DEG C, the stirring speed of the reactor is 80-120 rpm, and the reaction time is 3-5min; S2: feeding the mixture slurry produced in S1 and the returned material together into a mixing granulator continuously for granulation so as to produce feed grade granular calcium dihydrogen phosphate wet semi-finished product; S3: sending the feed grade granular calcium dihydrogen phosphate wet semi-finished product in S2 into a drying machine for drying; and S4: screening the dried finished product output from the drying machine in S3to obtain a calcium dihydrogen phosphate finished product, crushing the tailing left by screening and then retuning the crushed tailing as the returned material to S2 for mixing granulation.
Owner:YUNNAN PHOSPHATE CHEM GROUP CORP

Khosam oil suppository

The invention discloses a khosam oil suppository. An active component of khosam oil of the khosam oil suppository of the invention is loaded in a matrix in a form of particles. The khosam oil suppository of the invention has the advantages of both suppositories and particles, not only is suitable for rectal administration or vaginal administration to generate local and systemic effect, can effectively prevent adverse reactions of khosam oil, but also can control the drug release speed, give full play to the drug curative effect, and significantly improve patient compliance, and has significant treatment superiority when compared with commercially available khosam oil products and traditional common khosam oil suppositories.
Owner:上海庸善健康科技发展有限公司

Nano-emulsion in-situ gel for treating haemorrhoids

The invention relates to nano-emulsion in-situ gel for treating haemorrhoids. The gel comprises the following components by weight: 30-100g of sophora flavescens, 30-120g of salviae miltiorrhizae, 30-100g of wild chrysanthemum, 1-8g of borneol, 1-8g of menthol, 30-160g of polyoxyethylated castor oil, 10-80g of absolute ethyl alcohol, 5-60g of isopropyl myristate, 60-160g of poloxamer 407, and 5-80g of poloxamer 188. The nano-emulsion in-situ gel can infiltrate into a mucous membrane to play the effects of clearing heat, removing toxicity, drying dampness, relieving itching, activating blood circulation to remove stasis, diminishing edema and relieving pain, and can be used for promoting local blood circulation, and improving nutrition of peripheral tissues to achieve the aims of diminishing edema and inflammation, and relieving pain.
Owner:HENAN UNIV OF CHINESE MEDICINE

Method used for inactivating virus based on atmospheric pressure low temperature plasma activated solution

The invention discloses a method used for inactivating virus based on an atmospheric pressure low temperature plasma activated solution. The method comprises following steps: 1, gas is introduced intoan atmospheric pressure low temperature plasma generator so as to realize generation of an atmospheric pressure low temperature plasma through excitation; 2, an atmospheric pressure low temperature plasma activated solution is subjected to activation so as to obtain a plasma activated solution; 3, and the plasma activated solution is used for treating a solution containing virus. The method is capable of killing virus effectively; no toxicity, no irritation, and no peculiar smell is caused; environment pollution caused by activation of virus with chemical reagents such as formaldehyde is avoided; and in preparation process of the atmospheric pressure low temperature plasma activated solution, energy consumption is low, operation is convenient, and production cost is reduced effectively.
Owner:BEIJING ACADEMY OF AGRICULTURE & FORESTRY SCIENCES +1

Disbudding agent for bananas and application method of disbudding agent

InactiveCN105638735AHigh efficiency of sucking and killing rateQuick resultsPlant growth regulatorsBiocideFruit treeDisease
The invention belongs to the technical field of fruit tree cultivation and particularly relates to a disbudding agent for bananas and an application method of the disbudding agent. The disbudding agent for the bananas is prepared from the following components in parts by weight: 80 to 100 parts of biodiesel, 1 to 5 parts of methyl oleate and 3 to 15 parts of 2,4-d butylate. According to the disbudding agent for the bananas, disclosed by the invention, the damage to banana mother plants can be remarkably reduced and soil does not needed to be broken in the disbudding process, absorptive buds can be removed, the control over soil-borne diseases is facilitated, and the growth of mother plants can be promoted; the disbudding agent is high in killing efficiency of the absorptive buds, quick in result and free of relapse.
Owner:广西壮族自治区农业科学院生物技术研究所 +1

Ointment for clearing heat, cooling blood, stopping bleeding, diminishing swelling and promoting wound healing and preparation method thereof

The invention discloses ointment for clearing heat, cooling blood, stopping bleeding, diminishing swelling and promoting wound healing and a preparation method thereof. The ointment is prepared from the following raw materials: rheum officinale, rhizoma coptidis, radix notoginseng, radix angelicae dahuricae, colla corii asini, calcined dragon bones, rhizoma bletillae, myrrh, cuttlebone, radix rubiae, dragon's blood, pearl, borneol and liquorice roots. The ointment has very good curative effects on various skin trauma bleeding, ulcer, ulceration and the like, the treatment period is short, andthe pain and economic burden of a patient are greatly reduced. The ointment directly acts on an affected part, improves the absorption efficiency of medicines, promotes rapid healing of bleeding points and ulcer surfaces, has the advantages of rapid curative effect, short course of treatment, pure traditional Chinese medicine preparation, no toxic or side effect, wide and easily available medicinesource, convenient application, external application to the affected part, small dosage, no pain and no recurrence after healing.
Owner:XIAN CHIHO PHARMA

A kind of pharmaceutical composition for controlling prosperity and increasing production and application thereof

The invention belongs to the technical field of plant growth regulators, and relates to a pharmaceutical composition capable of controlling vigorous plant growth and increasing production and its application. The plant growth regulator pharmaceutical composition provided by the present invention, the active ingredients include: prohexadione calcium, paclobutrazol and a plant growth promoter; the plant growth promoter is sodium nitrophenolate, diethyl hexanoate or gibberellin. 25% prohexadione-calcium-paclobutrazol composite agent wettable powder is used to control the vigorous growth of crops, especially when used to control the vigorous growth of peanuts, soybeans or rapeseed, and the dosage of 20g / mu has the best effect. The plant growth regulator medicament composition provided by the invention belongs to a ternary compound product. Compared with the single use of prohexadione calcium to regulate the growth of crops, the cost is greatly reduced and the dosage is easy to control, and the crop yield is significantly increased; Paclobutrazol is much safer; compared with other triazole plant growth regulators that delay plant growth, it has the advantages of low residual toxicity, less dosage, and environmental friendliness.
Owner:郑州郑氏化工产品有限公司

Doxycycline hyclate injection and preparation process thereof

The invention belongs to the technical field of veterinary medicine and discloses doxycycline hyclate injection and a preparation process thereof.Every 100ml of the doxycycline hyclate injection comprises 4.2-12.4g of magnesium chloride complexing agent, 5-15g of doxycycline hyclate, 20-30ml of alpha-pyrrolidone, 10-20ml of dimethyl formamide, 10-20ml of glycerin methylal, 0.1-0.2g of antioxidant, 5-10g of cosolvent and the balance of injection water.The prepared doxycycline hyclate injection has the advantages that the doxycycline hyclate injection is light in color, good in stability, quick in action, definite in curative effect, convenient in veterinary clinical application and easy in dose control, the doxycycline hyclate injection has a certain long-acting effect and cannot be easily affected by other medicine, and the treatment effect and efficiency are increased.
Owner:安徽省兽药研发中心

Traditional Chinese medicine gel agent for treating cutaneous pruritus

The present invention discloses a traditional Chinese medicine gel agent for treating cutaneous pruritus. The traditional Chinese medicine gel agent consists of a traditional Chinese medicine active ingredient, an antibacterial active ingredient and a gel matrix, wherein the traditional Chinese medicine active ingredient is prepared by extraction and purification of 13 Chinese herbal medicines intotal which include fructus cnidii, radix sophorae flavescentis, cortex phellodendri, radix saposhnikoviae, cortex lycii radicis, fructus kochiae, radix clematidis, cortex dictamni, radix stemonae, rhizoma atractylodis, herba portulacae, folium artemisiae argyi and mint. By improving an existing traditional Chinese medicine extraction method, the active ingredient content and the curative effect of the medicines are improved, the prepared gel agent has the relatively high transdermal absorption performance, and compared with an existing dosage form, the traditional Chinese medicine gel agent has the advantages of convenient use, no residue, longer quality guarantee period and the like.
Owner:MAYINGLONG PHARMA GROUP

A clean cocoon cooking method

InactiveCN103225112BReduce adhesive forceDissociate smoothlySilk filament obtainingEngineeringChemical preparation
The invention discloses a cleaning cocoon cooking method. The method comprises the processes of: external vacuum infiltration, cooking by an automatic cooker, cocoon steaming, and adjustment, wherein a reelability agent originally used for cocoon cooking replaces a penetrating agent for penetrating to be used in the external vacuum infiltration cocoon cooking process; in the condition with 30-50 DEG C water temperature, the reelability agent can only have infiltration function with water to be adsorbed between cocoon layers and on the surface of a cocoon filament; and in the cocoon cooking process and in the condition with 60-80 DEG C water temperature, the reelability agent can promote the cocoon filament sericin dissolution to reduce adhesion between cocoon filaments for the smooth dissociation of the cocoon filaments, so that the reelability agent has the reelability function in the cocoon cooking process. One chemical preparation achieves two functions, the chemical preparation is less and easily controlled in dose, process is simple, operation is convenient, and production cost is low.
Owner:安徽绩溪县花神丝绸有限公司
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