324 results about "Cyclodextrin Derivatives" patented technology

A barrier film composition can comprise a thermoplastic web comprising a thermoplastic polymer and a dispersed cyclodextrin composition having substituents that compatibilize the cyclodextrin in the film. The thermoplastic / cyclodextrin film obtains substantial barrier properties from the interaction between the substituted cyclodextrin in the film material with a permeant. The substituents on the cyclodextrin molecule causes the cyclodextrin to be dispersible and stable in the film material resulting in an extrudable thermoplastic. Such materials can be used as a single layer film material, a multilayer film material which can be coated or uncoated and can be used in structural materials wherein the thermoplastic is of substantial thickness resulting in structural stiffness. The cooperation between the cyclodextrin and the thermoplastic polymer provides barrier properties to a web wherein a permeant can be complexed or entrapped by the cyclodextrin compound and held within the film preventing the permeant from passing through the film into the interior of a film, an enclosure or container. The permeant can comprise a variety of well known materials such as moisture, aliphatic or aromatic hydrocarbons, monomer materials, off flavors, toxic compounds etc.

The invention relates to a hydroxypropyl -sulfo butyl -ª‰-cyclodextrin and its preparing method, analysis method and the applying in medicine, wherein the hydroxypropyl -sulfo butyl -ª‰-cyclodextrin is the cyclodextrin derivation displaced by hydroxypropyl and sulfo butyl. The n-(2, 3, 6-O-2-hydroxypropyl )-m-(2, 3, 6-O-sulfo butyl)-ª‰-cyclodextrin, each mole cyclodextrin displaced group number is n hydroxypropyl and m sulfo butyl, wherein n is the average displaced degree of the hydroxypropyl displaced group; m is the average displaced degree of the sulfo butyl displaced group; n+mú¢Z is the total average displaced degree; nú¢any of the 1,2,3,4,5,6, 7,8,9; m=any of the 1,2,3,4,5,6, 7,8,9; z=any of the 1,2,3,4,5,6, 7,8,9,10.

The present invention is directed to pharmaceutical compositions comprising prasugrel and a cyclodextrin derivative, and methods of making and using the same.

An amorphous solid dispersion of tacrolimus comprising tacrolimus, a substituted cyclodextrin derivative and an organic acid, the solid dispersion having high thermodynamic stability and solubility, providing enhanced release rate and bioavailability.