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315results about How to "Small individual differences" patented technology

Method of manufacturing micro electro mechanical systems device

Provided is a MEMS device which is robust to the misalignment and does not require the double-side wafer processing in the manufacture of a MEMS device such as an angular velocity sensor, an acceleration sensor, a combined sensor or a micromirror. After preparing a substrate having a space therein, holes are formed in a device layer at positions where fixed components such as a fixing portion, a terminal portion and a base that are fixed to a supporting substrate are to be formed, and the holes are filled with a fixing material so that the fixing material reaches the supporting substrate, thereby fixing the device layer around the holes to the supporting substrate.
Owner:HITACHI LTD

Sparingly soluble active component particle, particle preparation and preparation method thereof

The invention discloses a sparingly soluble active component particle, a particle preparation and a preparation method thereof. The preparation method of the sparingly soluble active component particle comprises the following steps: dissolving sparingly soluble active component and ionic polymer into an alkaline solution or an acidic solution, and then mixing the alkaline solution and acidic solution to change the pH value of solutions so as to precipitate the sparingly soluble active component and ionic polymer from the mixed solution to form particles; and the performance of the sparingly soluble active component particle is improved. According to the preparation method, sparingly soluble active component and ionic polymer are co-precipitated, at the same time, a preparation technology is adopted, and two technologies are tightly combined to prepare the sparingly soluble active component particle preparation. The prepared preparation has the advantages of excellent dissolving-out characteristic, high bioavailability, small individual difference, good stability, and good content uniformity.
Owner:SINOTHERAPEUTICS

Electroencephalogram signal classifying and recognizing method based on regularized CSP and regularized SRC and electroencephalogram signal remote control system

The invention discloses an electroencephalogram signal classifying and recognizing method based on a regularized CSP and a regularized SRC and an electroencephalogram signal remote control system. The method includes the steps of collecting EEG signals produced when n experimenters imagine two different types of movement, and obtaining the covariance of training data of each experimenter, introducing a regularized parameter alpha and a regularized parameter beta (alpha is larger than or equal to zero and beta is smaller than or equal to one), constructing imagine space filters of two different types of movement, reserving the training data after filtering is conducted, extracting maximum vectors of two types of characteristics, constructing a learning dictionary, inputting test movement imagine data, conducting space filtering, and reserving test data after filtering is conducted, recognizing the test movement imagine data through a signal sparse representation method, and determining categories of test samples. The electroencephalogram signal remote control system comprises a signal collecting module, a signal analyzing module and a controller module. According to the electroencephalogram signal classifying and recognizing method based on the regularized CSP and the regularized SRC and the electroencephalogram signal remote control system, the electroencephalogram signals are classified and recognized through the regularized CSP and the regularized SRC, the problem of unstable characteristic extraction is effectively solved, and an electroencephalogram signal classifier has stronger robustness compared with an existing classifier.
Owner:XIDIAN UNIV

Foot-and-mouth disease genetic engineering mixed epitope vaccine and preparation method thereof

The invention discloses a foot-and-mouth disease genetic engineering mixed epitope vaccine and a preparation method thereof. The vaccine consists of the following four parts: a serial B cell epitope recombinant protein BI consisting of main neutralizing epitops of O-type foot-and-mouth disease viruses in Cathay, Transasia and Mya 98 pedigrees with a gene sequence of SEQ ID NO:1 and an amino acid sequence of SEQ ID NO:2, a T-cell epitope recombinant protein TI consisting of serial connection of universal T-cell epitope and a plurality of foot-and-mouth disease virus specific T-cell epitopes with a gene sequence of SEQ ID NO:3 and an amino acid sequence of SEQ ID NO:4, Toll-like receptor 3 agonist-polyinosinic acid-polycytidysic acid and/or Toll-like receptor7/8 agonist-R848 serving as immunopotentiator, and 201 oil adjuvant. When being used for immunizing a pig, the BI and TI mixed epitope vaccine prepared by utilizing the method can produce a protective immunization effect the same as or better than that of an inactivated influenza virus Vaccines, and has a cross protection effect to viruses of the three pedigrees, so that the vaccine is a novel immune-enhanced O-type foot-and-mouth genetic engineering mixed epitope vaccine.
Owner:LANZHOU INST OF VETERINARY SCI CHINESE ACAD OF AGRI SCI

Levetiracetam slow release pellet capsule preparation and preparation method thereof

The invention relates to a levetiracetam slow release pellet capsule preparation and a preparation method thereof. The levetiracetam slow release pellet capsule preparation comprises the following components in percentage by mass: 50-70 percent of levetiracetam, 15-30 percent of blank pellet, 5-10 percent of hydroxypropylmethyl cellulose or polyvidone, 7-15 percent of ethylcellulose or acrylic resin, 1-8 percent of talc powder and 0.5-2 percent of cataloid. The preparation method comprises the following steps: coating levetiracetam fine powder on the blank pellet by a binding agent to be madeinto a medicine-contained pellet; coating an isolating layer on the medicine-contained pellet; coating a slow release coating film on the medicine-contained pellet coated with the isolating layer to prepare a slow release pellet; and mixing the slow release pellet, the talc powder and the cataloid and filling the mixture into a capsule. The levetiracetam is made into the slow release capsule preparation by a pellet and slow release technology, and the slow release preparation can stabilize blood medicine concentration, reduce the generating frequency and degree of the side effect and fundamentally solve the problems of great influence on a tablet by gastric pyloric sphincter and big differences of gastric emptying individuals.
Owner:天津药物研究院药业有限责任公司

Aripiprazole solid preparation and preparation method thereof

The invention discloses the preparation method of aripiprazole solid preparation. The method comprises the following steps of dissolving aripiprazole into acidic solution containing an acidifying agent to obtain medicine-containing acidic solution; and then uniformly mixing accessory with the medicine-containing acidic solution to granulate by a wet method. The invention also discloses aripiprazole solid preparation prepared by the method. According to the method disclosed by the invention, the defects of the serious pollution, high loss and serous potential safety hazards brought by mechanical crushing treatment are avoided; and the method is simple, convenient and feasible for operation and easy for industrial production and has high safety coefficient. The aripiprazole solid preparation prepared by the method has the advantages of excellent dissolution property, stability, and content uniformity.
Owner:SHANGHAI ZHONGXI PHARMA +1

Intelligent sensing blanket

InactiveCN105832348AComfortable flight experienceLow eigenvalue stabilityEvaluation of blood vesselsSensorsEngineeringHigh body temperature
The invention discloses an intelligent sensing blanket, which comprises a central processing unit as well as an emotion sensing module, a brain wave sensing module, a body temperature sensing module and a sitting posture sensing module which are in wireless connection to the central processing unit, wherein the emotion sensing module is used for determining the variety of sensed emotion in accordance with analyzed target emotion physiological response characteristics and combinations thereof; the brain wave sensing module comprises a plurality of brain wave sensors, a brain wave processing unit, a power management module and a brain wave sleep promoting unit; a non-contact infrared temperature sensor is arranged in the body temperature sensing module; and an acceleration meter and a tension sensor are arranged in the sitting posture sensing module. The intelligent sensing blanket disclosed by the invention, by virtue of the emotion sensing module, the brain wave sensing module and the body temperature sensing module, can sense emotion, brain wave signal and body temperature of passengers so as to regulate environment in a cabin; and by virtue of the sitting posture sensing module, the sitting posture of the passengers can be sensed and the posture of seats can be automatically regulated, so as to offer a more comfortable flying experience to the passengers in a long airline journey.
Owner:NINGBO YUAN DING ELECTRONICS TECH CO LTD

Tamsulosin hydrochloride double-layer osmotic pump controlled-releasing tablet and preparation method thereof

The invention provides double-layer osmotic pump tablets of tamsulosin ehydrochloride and a process for preparation. The medicament contains tamsulosin ehydrochloride and acceptable medical polymeric excipient, and is characterized in that the invention has excellent zero-level controlled releasing, pH level of environment, movements of the stomach and intestine, and food, has little effect on releasing action and food, and has no effect on the internal pharmacokinetics parameter. According to the percentage by weight, the preparation contains tamsulosin ehydrochloride 0-2%, excipient in pastille layer with the function of controlled-releasing 30-70% excipient in boosting layer with the function of controlled releasing 30-70%, and the rest percentage of other excipient. The of process for preparation the double layer permeable pump controlled-release tablets of tamsulosin ehydrochloride comprises (1) the preparation of pastille layer, (2) the preparation of boosting layer, (3) the compressing of the two layers, (4) the coating of the double layer tablets, (5) the perforating of the coated tablets, (6) the packing of moisture proof cost. The invention is clinically used for the treatment of paruria symptom like frequent micturition, diuresis at night, dysuria caused by prostatic hyperplasia.
Owner:SHANGHAI INST OF MATERIA MEDICA CHINESE ACAD OF SCI +1
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