315results about How to "Small individual differences" patented technology

Provided is a MEMS device which is robust to the misalignment and does not require the double-side wafer processing in the manufacture of a MEMS device such as an angular velocity sensor, an acceleration sensor, a combined sensor or a micromirror. After preparing a substrate having a space therein, holes are formed in a device layer at positions where fixed components such as a fixing portion, a terminal portion and a base that are fixed to a supporting substrate are to be formed, and the holes are filled with a fixing material so that the fixing material reaches the supporting substrate, thereby fixing the device layer around the holes to the supporting substrate.

The invention discloses a sparingly soluble active component particle, a particle preparation and a preparation method thereof. The preparation method of the sparingly soluble active component particle comprises the following steps: dissolving sparingly soluble active component and ionic polymer into an alkaline solution or an acidic solution, and then mixing the alkaline solution and acidic solution to change the pH value of solutions so as to precipitate the sparingly soluble active component and ionic polymer from the mixed solution to form particles; and the performance of the sparingly soluble active component particle is improved. According to the preparation method, sparingly soluble active component and ionic polymer are co-precipitated, at the same time, a preparation technology is adopted, and two technologies are tightly combined to prepare the sparingly soluble active component particle preparation. The prepared preparation has the advantages of excellent dissolving-out characteristic, high bioavailability, small individual difference, good stability, and good content uniformity.

The invention relates to a method for realizing vector electrocardiograph, which projects the solid heart vectors on the front, horizontal, and side three planes, to form a plane electrocardiograph vector diagram, and sets the projections of several virtual lines on different angles and three plant rings, to form the liner expressed vector electrocardiograph. The virtual lines have 0-18 axles in 0-360 degrees of each plane to generate total 54 vector electrocardiographs. The invention can generate 1-78 coupled synchronous and / or selective twelve electrocardiographs, vector electrocardiograph, time electrocardiograph, steering time electrocardiograph, continuous electrocardiograph, or the like, while it can synchronously switch between one-dimension, two-dimension and three-dimension electrocardiographs.

The invention provides a film forming compound with modified starch as the main component, a film forming material containing the compound, and more particularly a hard-shell natural capsule made from the compound. The compound contains no or very little animal protein such as gelatin, etc. The compound can partially or completely replace the gelatin from animals for producing natural hard-shell capsules. The prepared natural capsule shell product has the advantages of excellent film forming property, high strength, good flexibility, high transparency, decomposability and microbial pollution resistance. The main component of the compound, modified starch, has stable quality and highly controllable performance.

The invention discloses an electroencephalogram signal classifying and recognizing method based on a regularized CSP and a regularized SRC and an electroencephalogram signal remote control system. The method includes the steps of collecting EEG signals produced when n experimenters imagine two different types of movement, and obtaining the covariance of training data of each experimenter, introducing a regularized parameter alpha and a regularized parameter beta (alpha is larger than or equal to zero and beta is smaller than or equal to one), constructing imagine space filters of two different types of movement, reserving the training data after filtering is conducted, extracting maximum vectors of two types of characteristics, constructing a learning dictionary, inputting test movement imagine data, conducting space filtering, and reserving test data after filtering is conducted, recognizing the test movement imagine data through a signal sparse representation method, and determining categories of test samples. The electroencephalogram signal remote control system comprises a signal collecting module, a signal analyzing module and a controller module. According to the electroencephalogram signal classifying and recognizing method based on the regularized CSP and the regularized SRC and the electroencephalogram signal remote control system, the electroencephalogram signals are classified and recognized through the regularized CSP and the regularized SRC, the problem of unstable characteristic extraction is effectively solved, and an electroencephalogram signal classifier has stronger robustness compared with an existing classifier.

The invention discloses a global positioning system (GPS) / global navigation satellite system (GLONASS) dual-system combination simulator and a GPS / GLONASS dual-system combination simulation method. Based on a hardware platform consisting of a digital signal processor (DSP) information processing module, a field programmable gate array (FPGA) signal processing module, two D / A conversion modules, an up-conversion module and a transmission antenna or output cable, a GPS satellite channel and a GLONASS satellite channel which are independent of each other are separated to realize GPS / GLONASS dual-system combination simulation. In the simulator and the simulation method, not only an independent GPS satellite signal and an independent GLONASS satellite signal can be simulated in an independent processing way, but also the coordinate system uniformization and time system synchronization of two systems can be realized, thereby effectively shortening a research and development cycle, reducing the receiver research and development cost and bringing convenience to the construction of a testing environment.

The invention discloses a method for preparing a solid preparation, which comprises the following steps of: dissolving active ingredients of water-insoluble and / or lowly water-soluble alkaline medicaments in acidulant-containing acid solution to prepare medicament-containing acid solution; and mixing the medicament-containing acid solution and auxiliary materials uniformly to perform wet-method pelletizing. The invention also discloses the solid preparation prepared by the method. By the method, the defects of serious pollution, large loss and serious potential safety hazard which are caused by mechanical pulverization are overcome, and the method is easy and convenient to operate, has high safety factors and is applied to industrial production easily. The solid preparation prepared by the method has the excellent dissolution characteristic, stability and content uniformity.

The invention provides a 3D scanning and model measurement integrated internet clothing customization system, and relates to a visual and human body data acquisition and size extraction integrated solution based on the 3D technology for especially aiming at e-commerce clothing customization. A 3D scanning system is connected with a portable 3D scanner to scan a user body through a 3D scanning port so as to establish a 3D model and transmit the 3D model to a data analysis terminal; the data analysis terminal performs interactive semi-automatic measurement on the human body 3D model to extract the size of the body and transmit the data to a visual e-commerce operating platform system; the visual e-commerce operating platform system comprises a clothing style customization visual design module, an order management module and a body measurement management module; the body measurement management module receives the body measurement requirement of the user and transmits the body measurement size to the user for his own use; and the visual e-commerce operating platform system matches the human body size and the style so as to be transmitted to an intelligent processing factory to perform clothing production.

The invention discloses a foot-and-mouth disease genetic engineering mixed epitope vaccine and a preparation method thereof. The vaccine consists of the following four parts: a serial B cell epitope recombinant protein BI consisting of main neutralizing epitops of O-type foot-and-mouth disease viruses in Cathay, Transasia and Mya 98 pedigrees with a gene sequence of SEQ ID NO:1 and an amino acid sequence of SEQ ID NO:2, a T-cell epitope recombinant protein TI consisting of serial connection of universal T-cell epitope and a plurality of foot-and-mouth disease virus specific T-cell epitopes with a gene sequence of SEQ ID NO:3 and an amino acid sequence of SEQ ID NO:4, Toll-like receptor 3 agonist-polyinosinic acid-polycytidysic acid and / or Toll-like receptor7 / 8 agonist-R848 serving as immunopotentiator, and 201 oil adjuvant. When being used for immunizing a pig, the BI and TI mixed epitope vaccine prepared by utilizing the method can produce a protective immunization effect the same as or better than that of an inactivated influenza virus Vaccines, and has a cross protection effect to viruses of the three pedigrees, so that the vaccine is a novel immune-enhanced O-type foot-and-mouth genetic engineering mixed epitope vaccine.

The invention relates to a method for preparing kabalatin adhere agent for treating senile dementia, wherein said adhere agent can stably hold blood drug density and reduce feeding time, with high safety.

A liquid preparation of meloxican is prepared from the meloxicam or its medical salt and water-soluble cyclodextrin derivative HP-beta-CD used as solubilizer and stabilizer, proportionally mixing, adding cosolvent, pH regulator and water for injection, heating and membrane filtering. It has long storage time at low temp.

The invention discloses nifedipine controlled release medicament, which contains a pastille layer and a boosting layer with the proportion of 1: 0.5-3 by weight, wherein the pastille layer contains nifedipine and carrying agent which is the homopolymer of vinylpyrrohdone and / or copolymer of vinylpyrrohdone and is 40-99% of the pastille layer, the boosting layer includes infiltration promoting polymer which is 10-80% of the boosting layer by weight, insoluble polymer which is 10-80% of the boosting layer by weight, and the other component is osmotic pressure accelerant The rate of medicament releasing controlled by nifedipine can make the medicament release the nifedipine in 24 hours by administering drug once a day.

The invention discloses a biguanide anti-diabetes medicine, in particular to a metformin hydrochloride enteric-coated medicine compound. The medicine compound is provided with a. a hollow pill core; b. a biguanide anti-diabetes medicine active component layer which is covered outside the hollow pill core; c. an enteric-coated layer which is covered outside the biguanide anti-diabetes medicine active component layer. The invention also discloses a method of preparing the medicine compound.

The invention relates to a levetiracetam slow release pellet capsule preparation and a preparation method thereof. The levetiracetam slow release pellet capsule preparation comprises the following components in percentage by mass: 50-70 percent of levetiracetam, 15-30 percent of blank pellet, 5-10 percent of hydroxypropylmethyl cellulose or polyvidone, 7-15 percent of ethylcellulose or acrylic resin, 1-8 percent of talc powder and 0.5-2 percent of cataloid. The preparation method comprises the following steps: coating levetiracetam fine powder on the blank pellet by a binding agent to be madeinto a medicine-contained pellet; coating an isolating layer on the medicine-contained pellet; coating a slow release coating film on the medicine-contained pellet coated with the isolating layer to prepare a slow release pellet; and mixing the slow release pellet, the talc powder and the cataloid and filling the mixture into a capsule. The levetiracetam is made into the slow release capsule preparation by a pellet and slow release technology, and the slow release preparation can stabilize blood medicine concentration, reduce the generating frequency and degree of the side effect and fundamentally solve the problems of great influence on a tablet by gastric pyloric sphincter and big differences of gastric emptying individuals.

The invention discloses the preparation method of aripiprazole solid preparation. The method comprises the following steps of dissolving aripiprazole into acidic solution containing an acidifying agent to obtain medicine-containing acidic solution; and then uniformly mixing accessory with the medicine-containing acidic solution to granulate by a wet method. The invention also discloses aripiprazole solid preparation prepared by the method. According to the method disclosed by the invention, the defects of the serious pollution, high loss and serous potential safety hazards brought by mechanical crushing treatment are avoided; and the method is simple, convenient and feasible for operation and easy for industrial production and has high safety coefficient. The aripiprazole solid preparation prepared by the method has the advantages of excellent dissolution property, stability, and content uniformity.

The invention provides a compound preparation of pioglitazone hydrochloride and metformin hydrochloride bilayer osmotic pump controlled release tablets. The compound preparation structurally comprises the following parts from inside to outside in sequence: a tablet core comprising a drug layer and a digestive layer, an insulation coating layer, a controlled release coating film with drug release holes, a rapid pioglitazone hydrochloride release layer and an unnecessary attractive coating. The invention also provides a preparation method of the compound preparation of pioglitazone hydrochloride and metformin hydrochloride bilayer osmotic pump controlled release tablets. The preparation method comprises the following steps of: (1) preparing the drug layer; (2) preparing the digestive layer; (3) tabletting the tablet core; (4) coating insulation coating layer; (5) coating the controlled release coating; (6) punching the coated tablet: (7) coating the rapid pioglitazone hydrochloride release layer; and (8) coating the attractive coating.

[Problem] To provide an electric power steering device capable of reducing a sense of discomfort due to noise when steering or when executing low-speed steering, and capable of achieving smooth steering without phase delay during high-speed steering. [Solution] An electric power steering device includes a torque control unit that computes a current command value on the basis of at least a steering torque, and assist-controls a steering system by driving a motor using a current control system based on the current command value. The electric power steering device is provided with: a motor angular velocity computing unit that computes a motor angular velocity from a motor rotation angle; a motor angular acceleration computing unit that computes a motor angular acceleration from the motor angular velocity; and a stability compensation unit that computes a compensation steering torque and a compensation current command value on the basis of the motor angular velocity and the motor angular acceleration (and additionally the vehicle speed as necessary), wherein the steering torque is compensated using the compensation steering torque and the current command value is compensated using the compensation current command value.

The invention discloses an intelligent sensing blanket, which comprises a central processing unit as well as an emotion sensing module, a brain wave sensing module, a body temperature sensing module and a sitting posture sensing module which are in wireless connection to the central processing unit, wherein the emotion sensing module is used for determining the variety of sensed emotion in accordance with analyzed target emotion physiological response characteristics and combinations thereof; the brain wave sensing module comprises a plurality of brain wave sensors, a brain wave processing unit, a power management module and a brain wave sleep promoting unit; a non-contact infrared temperature sensor is arranged in the body temperature sensing module; and an acceleration meter and a tension sensor are arranged in the sitting posture sensing module. The intelligent sensing blanket disclosed by the invention, by virtue of the emotion sensing module, the brain wave sensing module and the body temperature sensing module, can sense emotion, brain wave signal and body temperature of passengers so as to regulate environment in a cabin; and by virtue of the sitting posture sensing module, the sitting posture of the passengers can be sensed and the posture of seats can be automatically regulated, so as to offer a more comfortable flying experience to the passengers in a long airline journey.

The invention relates to a poisonous and harmful gas detection chip and a preparation method thereof. For a chip detection system, a reaction microchannel, a fluid microchannel, an electrode microchannel and a microfluid driving region are processed on a microfluidic chip, so that the integration of a plurality of functional units is realized. An electrochemical oxidation / reduction reaction of poisonous and harmful gas is performed on the surface of an electrode slice embedded in the reaction microchannel; electrolysis is carried out to generate the change of an electrochemical signal; and an electrochemical detector obtains the type and concentration information of the analysed gas by analysing the change of the electrochemical signal.

The present invention discloses the tissue cultivation process for quickly breeding Dysosma versipellis. The process includes selection and processing of explant, inducing culture, proliferating culture, rooting culture, transplanting and other steps. The present invention uses MS culture medium with added auxiliary agents including active carbon, 6-benzyl adenine, gibberellin and corn extract for two key stages including the inducing growth of fascicular seedling and rooting of robust seedling. The present invention solves the technological problems in fast breeding and stable rooting of Dysosma versipellis, and has the advantages of high breeding coefficient, stable technology, short seedling growth period and low cost.

The invention discloses a zolpidem tartrate oral spraying agent and a preparation method thereof. The oral spraying agent uses water as a solvent and 100ml of oral spraying agent comprises 1 to 10g of zolpidem tartrate, 0.1 to 50g of solubilizer, 0.1 to 5g of sorbefacient, 0.01 to 5g of flavoring agent and 0.1 to 3g of antioxidant. After the zolpidem tartrate oral spraying agent is sprayed and taken by oral cavity or hypoglottis, the medicament is mainly absorbed through the oral cavity or sublingual mucosa to avoid first pass effect of liver and food influence; therefore, the medicament is absorbed more rapidly, takes effect more quickly, and has smaller individual difference; and the medicament has convenient use, is taken without water before bedtime, and is particularly suitable for patients who are incompliant to oral administration and injection. Due to wide distribution range of the medicament in oral mucosa after spraying and administration and the effect of the sorbefacient, the medicament is rapidly absorbed from the oral mucosa and has quick-acting effect.

The invention provides a film forming compound with modified starch as the main component, a film forming material containing the compound, and more particularly a hard-shell natural capsule made from the compound. The compound contains no or very little animal protein such as gelatin, etc. The compound can partially or completely replace the gelatin from animals for producing natural hard-shell capsules. The prepared natural capsule shell product has the advantages of excellent film forming property, high strength, good flexibility, high transparency, decomposability and microbial pollution resistance. The main component of the compound, modified starch, has stable quality and highly controllable performance.

The invention provides double-layer osmotic pump tablets of tamsulosin ehydrochloride and a process for preparation. The medicament contains tamsulosin ehydrochloride and acceptable medical polymeric excipient, and is characterized in that the invention has excellent zero-level controlled releasing, pH level of environment, movements of the stomach and intestine, and food, has little effect on releasing action and food, and has no effect on the internal pharmacokinetics parameter. According to the percentage by weight, the preparation contains tamsulosin ehydrochloride 0-2%, excipient in pastille layer with the function of controlled-releasing 30-70% excipient in boosting layer with the function of controlled releasing 30-70%, and the rest percentage of other excipient. The of process for preparation the double layer permeable pump controlled-release tablets of tamsulosin ehydrochloride comprises (1) the preparation of pastille layer, (2) the preparation of boosting layer, (3) the compressing of the two layers, (4) the coating of the double layer tablets, (5) the perforating of the coated tablets, (6) the packing of moisture proof cost. The invention is clinically used for the treatment of paruria symptom like frequent micturition, diuresis at night, dysuria caused by prostatic hyperplasia.

The invention provides a ginkgolide osmotic pump tablet and a preparation method thereof. The ginkgolide osmotic pump tablet provided by the invention is a double-layer tablet composed of a drug-containing layer and a push layer, and is coated, wherein the drug-containing layer comprises drug release holes. The ginkgolide osmotic pump tablet uses ginkgolide at effective positions of the ginkgo biloba extract as an active component, and a total amount of ginkgolide A, ginkgolide B, ginkgolide Cand bilobalide is not less than 70 %. According to the invention, by combining a solid dispersion solubilising technique and an osmotic pump tablets control-release technology, the ginkgolide is firstly prepared into the solid dispersion, and then further prepared into the ginkgolide osmotic pump tablet on a basis of improving solubility of poorly soluble components, thereby realizing synchronous slow release of complex components in the ginkgolide, reducing drug administration times and improving patient compliance.

A Chinese medicine in the form of suppository for treating lumbar vertebra disease, lumbar intervertebral disc protrusion, tonic rachitis and hyperosteogeny is prepared from 9 Chinese-medicinal materials including astragalus root, capejasmine fruit, musk, cinnamon twig, etc through pulverizing, extracting in alcohol, filtering, concentrating by distilling, to obtain concentrated liquid, immersing catgut suture in physiologic saline, baking, shearing short, putting them in bottle, filling said concentrated liquid, sealing and magnetizing.

The invention provides an atomizing inhalation system. The system comprises an integrated distribution box, a distribution box shell, an atomizing box, an oxygen box, supporting pillars, a first oxygen tube, a second oxygen tube, an oxygen supply source distribution chamber, a valve, a ventilating device, a ventilating device shell, an electric telescopic rod, a ventilating baffle, a limiting plate, an air screen, a treatment device, an adjustor, an allowance displayer and an oxygen supply source. An electronic medical treatment information end, an emotion sensing module, a brain wave sensing module, a body temperature sensing module, a remote diagnosis unit and a monitoring system are arranged inside the integrated distribution box. Through the integrated distribution box, oxygen is directly atomized through the atomizing box, atomizing time is shortened, and operation is convenient for medical workers; through the emotion sensing module and the brain wave sensing module, the mental condition of a patient is monitored in real time; treatment conditions are monitored in real time through the body temperature sensing module, electronic medical treatment information end, a remote diagnosis unit and the monitoring system, and the accuracy and safety of treatment are guaranteed.

A Chinese medicine in the form of suppository for treating lumbar vertebra disease, lumbar intervertebral disc protrusion, tonic rachitis and hyperosteogeny is prepared from 10 Chinese-medicinal materials including astragalus root, capejasmine fruit, musk, cinnamon twig, etc through pulverizing, extracting in alcohol, filtering, concentrating by distilling, to obtain concentrated liquid, immersing catgut suture in physiologic saline, baking, shearing short, putting them in bottle, filling said concentrated liquid, sealing and magnetizing.

The invention provides a glipizide loaded controlled release preparation, which comprises a pastille layer and a boosting layer with the weight ratio of 1:0.5 to 3, the pastille layer comprises glipizide and carrier, the carrier is ethane ketopyrrolidine homopolymer and / or ethane ketopyrrolidine copolymer occupying 40 to 99 percent of the weight of the pastille layer; the boosting layer at least comprises infiltration promoting polymer occupying 10 to 80 percent of the weight of the boosting layer, 10 to 80 percent of insoluble polymer and residual osmotic pressure accelerant; the glipizide of the invention can be controlled to release a drug so as to lead the preparation to attain the purpose that the drug is administrated one time a day, and the glipizide can be released in 24 hours.