The invention provides a tamsulosin sustained release pellet. The tamsulosin sustained release pellet comprises a medicine-containing pellet core and a sustained release coating layer, wherein the sustained release coating layer comprises a hydrophobic matrix and a hydrophilic polymer which is sensitive to pH values. The pH values of a high molecular polymer in the dissolving process are 1 to 14, so that medicines are released at different pH values; and simultaneously, the high molecular polymer can be used as a carrier for controlling tamsulosin to be released, so that a prescription is simplified, preparation difficulties are reduced, and the tamsulosin sustained release pellet is easy to industrially produce in batches. Surprisingly, the preparation can be used for preparing various tamsulosin sustained release formulations without dependence on the physicochemical property of the tamsulosin.