35 results about "Before Bedtime" patented technology

A novel sleep regulating pharmaceutical formulation is introduced, typically implementing two principal drugs having actions which are reversive to one another, yet incorporated into a unitary solid dosage, and prepared for oral administration before bedtime. Usually, structure is configured to initially release a calmative or other sleep-compatible substance by prompt dissolution. The initial release is followed by a specific period of delay, which in basic formulations entails no release of any drug, and which allows a nominal interval of sleep. At the terminus of the delay, a final agent is released to induce wakeup. Incorporation of agents of opposite action within a unitary dosage form renders utility which is uniquely appropriate to the invention. In a preferred embodiment, delay of release and final delivery of wakeup agent are arranged by a dialysis membrane which eventually bursts as a result of osmotic pressure generated by a hydrophilic core.

A novel sleep regulating pharmaceutical formulation is introduced, typically implementing two principal drugs having actions which are reversive to one another, yet incorporated into a unitary solid dosage, and prepared for oral administration before bedtime. Usually, structure is configured to initially release a calmative or other sleep-compatible substance by prompt dissolution. The initial release is followed by a specific period of delay, which in basic formulations entails no release of any drug, and which allows a nominal interval of sleep. At the terminus of the delay, a final agent is released to induce wakeup. Incorporation of agents of opposite action within a unitary dosage form renders utility which is uniquely appropriate to the invention. In a preferred embodiment, delay of release and final delivery of wakeup agent are arranged by a dialysis membrane which eventually bursts as a result of osmotic pressure generated by a hydrophilic core.

A daily urinary excretion measurement apparatus and a method thereof, for measuring daily excretion of a urine component highly accurately and easily, are provided. A daily urinary excretion measurement apparatus (100) includes: a urine component calculation unit (411) which measures the amount of the urine component included in before-bedtime urine that is excreted for the last time before bedtime in the day and the amount (salt) of the urine component (salt) included in overnight urine that is excreted for the first time after wake-up on the next day following a sleep; a regression equation storage unit (416) which stores a correlation (a regression equation) between the amount of the before-bedtime urine component and the amount of the overnight urine component and a total amount of the urine component included in daily urine; a daily urinary excretion calculation unit (413) which calculates the total amount of the urine component excreted in the daily urine according to the regression equation stored in the regression equation storage unit (416), using the amount of the before-bedtime urine component (salt) and the amount of the overnight urine component (salt) calculated by the urine component calculation unit (411).

A method of promoting sleep in a patient with overactive bladder, comprising: administering trospium chloride at or shortly before bedtime, to a patient with overactive bladder disease, in an amount sufficient to reduce wakefulness throughout the patient's normal sleep period.

The invention discloses a zolpidem tartrate oral spraying agent and a preparation method thereof. The oral spraying agent uses water as a solvent and 100ml of oral spraying agent comprises 1 to 10g of zolpidem tartrate, 0.1 to 50g of solubilizer, 0.1 to 5g of sorbefacient, 0.01 to 5g of flavoring agent and 0.1 to 3g of antioxidant. After the zolpidem tartrate oral spraying agent is sprayed and taken by oral cavity or hypoglottis, the medicament is mainly absorbed through the oral cavity or sublingual mucosa to avoid first pass effect of liver and food influence; therefore, the medicament is absorbed more rapidly, takes effect more quickly, and has smaller individual difference; and the medicament has convenient use, is taken without water before bedtime, and is particularly suitable for patients who are incompliant to oral administration and injection. Due to wide distribution range of the medicament in oral mucosa after spraying and administration and the effect of the sorbefacient, the medicament is rapidly absorbed from the oral mucosa and has quick-acting effect.

A daily urinary excretion measurement apparatus and a method thereof, for measuring daily excretion of a urine component highly accurately and easily, are provided.A daily urinary excretion measurement apparatus (100) includes: a urine component calculation unit (411) which measures the amount of the urine component included in before-bedtime urine that is excreted for the last time before bedtime in the day and the amount (salt) of the urine component (salt) included in overnight urine that is excreted for the first time after wake-up on the next day following a sleep; a regression equation storage unit (416) which stores a correlation (a regression equation) between the amount of the before-bedtime urine component and the amount of the overnight urine component and a total amount of the urine component included in daily urine; a daily urinary excretion calculation unit (413) which calculates the total amount of the urine component excreted in the daily urine according to the regression equation stored in the regression equation storage unit (416), using the amount of the before-bedtime urine component (salt) and the amount of the overnight urine component (salt) calculated by the urine component calculation unit (411).

The invention aims to provide a preparation for treating panasthenia, which comprises the following components by weight: 15 grams of root of red-rooted salvia, 15 grams of tuber fleeceflower stem, 12 grams of thinleaf milkwort root-bark, 12 grams of date seed, 12 grams of silktree albizzia bark, 15 grams of blighted wheat, 6 grams of honey-fried liquoric root and 10 grams of red date. The components are used to make one dose and are decocted in water twice to prepare the preparation. The first-time liquid medicine is administrated before bedtime, and the second-time liquid medicine is administrated in the morning.

A method for protection of a mammal that has impaired glucose tolerance or early stage diabetes mellitus from developing overt or insulin dependent diabetes comprises administering an orally effective dose of a pharmaceutical formulation comprising insulin at nighttime, e.g., at or shortly before bedtime.

A method for protection of a mammal that has impaired glucose tolerance or early stage diabetes mellitus from developing overt or insulin dependent diabetes comprises administering an orally effective dose of a pharmaceutical formulation comprising insulin at nighttime, e.g., at or shortly before bedtime.

The invention relates to production and use methods of a traditional Chinese medicine composition for treating ulcerative colitis. The production and use methods comprise the following steps: adding water to decoct the raw material medicines of astragalus membranaceus, codonopsis pilosula, angelica sinensis, carbonized sanguisorba root, coptis chinensis, scutellaria baicalensis, golden cypress, fructus aurantii, elecampane and the like with a slow fire, sterilizing under a high pressure, and carrying out coloclyster before bedtime every night.

The invention discloses a medicine for treating gastritis. The medicine is prepared by adding 500g of water to decoct 10g of yerbadetajo herb, 10g of ovateleaf holly bark, 10g of giant knotweed rhizome, 10g of seed of masaikai caper, 6g of Mongolian dandelion herb, 6g of cassia twig, 6g of herb of hard bluegrass and 3g of cuttlebone for 30 minutes. When the medicine is used, patients take the prepared liquor in twice, once after getting up in the morning and once before bedtime in the evening and recover 10 days later. More than 200 patients are cured through clinical practical application of the medicine.

The invention provides a method for treating hormone dependence dermatitis. The method comprises the following steps of: externally applying Daibo plaster before bedtime, and performing moxa-wool moxibustion by using a moxa stick at the same time, wherein the moxa-wool moxibustion is performed for 10 to 20min each time, and the moxa stick is at the distance of 4 to 6mm away from facial skin; and washing the Daibo plaster the next morning, and then coating vitamin E ointment at afflicted parts. The method has the advantages that: the effects of heat clearing, dampness drying, moisturizing and itching relieving can be achieved by the Daibo plaster; the effects of warming channels, freeing network vessels, circulating local qi and blood, opening up sweat pores and removing toxin along with sweat can be achieved by the moxa-wool moxibustion; the two therapeutic methods are combined, namely cooling and heating are combined, and opening and closing are combined, so that the symptoms of the hormone dependence dermatitis can be effectively improved, remarkable curative effects are achieved, primary and secondary aspects are treated at the same time, and the recurrence rate is low; and the method is a Chinese medicinal treatment method, and compared with methods adopting chemical synthetic medicaments such as tacrolimus ointment, is high in safety and free of toxic and side effects.

The invention relates to production and use methods of a traditional Chinese medicine composition for treating chronic pelvic inflammation. The production and use methods comprise the following steps: adding water to decoct the raw material medicines of sophora flavescens, dandelion, ixeris sonchifolia, eucommia ulmoides, salvia miltiorrhiza, rheum officinale, safflower carthamus and the like with a slow fire, sterilizing under a high pressure, and carrying out coloclyster by 200ml before bedtime.

The invention discloses a preparation method of a stomach-invigorating wine. The preparation method is characterized by comprising the following steps: (1) selecting materials including yellow wine, goat milk, malt, endothelium corneum gigeriae galli, glycyrrhiza, radix pseudostellariae and hawthorn; (2) blending the materials in the step (1) according to a weight ratio of 5:2:1:1:1:2:1; (3) stirring uniformly, sealing and storing for 8 to 10 days, and inversing twice per day during storage. The preparation method provided by the invention is easy to operate, and is suitable for common familise. The prepared cocktail is healthy and nutritious, and can improve sleep quality if drinking before bedtime.

The invention discloses a medicine for treating acute enteritis. The medicine is prepared by adding 500g of water to decoct 2g of parslane herb, 2g of raphanus raphanistrum, 20g of dried white turnip and 10g of fresh ginger for 30 minutes. When the medicine is used, patients take the prepared liquor once after getting up in the morning and once before bedtime in the evening and recover three days later. More than 200 patients are cured through clinical practical application of the medicine.

The invention discloses a preparation method of a spleen-tonifying wine. The preparation method is characterized by comprising the following steps: (1) selecting materials including a glutinous rice wine, milk, millet, wheat, gaze and Chinese yam; (2) blending the materials of the first step according to a weight ratio of 5:2:1:1:1:2; (3) stirring uniformly, sealing and storing for 6 to 8 days, and inversing the wine twice per during storage. The preparation method provided by the invention is easy to operate, and is suitable for common families. The prepared cocktail is healthy and nutritious, and can improve sleep quality if drinking before bedtime.

The invention discloses a sleep-inducing nutrient powder and a processing method thereof. The nutrient powder comprises the following raw materials in parts by weight: 30-35 parts of oat, 3-5 parts of fleeceflower roots, 10-15 parts of lotus seeds, 5-8 parts of bananas, 5-8 parts of Chinese dates, 10-15 parts of asparagus lettuce, and 3-5 parts of cane sugar. The invention also discloses a processing method of the sleep-inducing nutrient powder. The method comprises the following eight processes: oat pulverizing, fleeceflower root pulverizing, lotus seed pulverizing, banana spraying pulverizing, Chinese date pulverizing, asparagus lettuce pulping pulverizing, mixing and sieving, and sterilization and packaging so as to obtain the green and healthy nutrient powder which can effectively aid sleep. The sleep-inducing nutrient powder provided by the invention needs to be taken after mixing with 10-20g of boiled water before bedtime, so that water drinking before bedtime is guaranteed and effective sleep-inducing components are ingested so as to help nourish blood, quiet spirit, lift sleepiness, and realize a sleep-inducing effect. The sleep-inducing nutrient powder provided by the invention contains no additive, has no side effect, and is green, healthy, and worth popularization.

The invention relates to a fast dissolving granulate obtainable by spray-dying of a composition comprising a dry methanolic or ethanolic extract of valerian root, a dry methanolic extract of hop strobiles, optionally a carrier, one or more artificial sweeteners, one or more flavoring agents, optionally an acidifier and water for the treatment of sleep disorders, wherein the said granulate is to be administered upon dissolution in water or an aqueous beverage shortly before bedtime.

An embodiment of the invention provides black tea and a preparation method thereof. The preparation method comprises steps as follows: edible cactuses are picked, subjected to thorn removal, washed and then cut; the cut edible cactuses are placed in a cool and dark place for withering, and the moisture mass percent of the withered edible cactuses is 60%-70%; the withered edible cactuses are rolled and then air-dried, and rolling and air-drying operation steps are repeated until the moisture mass percent of the edible cactuses is 10%-12%; the edible cactuses processed in the above steps are fermented at the temperature of 26-28 DEG C for 8-10 h and then dried until the moisture mass percent is 5%-8%; the edible cactuses are packaged and then placed in a dry and dark environment for storage. The prepared black tea has effects of clearing lung heat, relieving coughs, cooling blood, eliminating toxins, nourishing the stomach, relieving alcoholism, calming nerves, helping sleeping and relieving constipation conditions, so that the black tea can be drunk without time limit and cannot affect the sleep quality even if the black tea is drunk before bedtime.

The invention relates to a prostate health-care wine and a preparation method thereof. The prostate health-care wine is prepared from corn wine and contains the effective components of antler, eucommia, wolfberry fruit, Chinese angelica, polygonatum canaliculatum, corydalis tuber, mint, honeysuckle, prepared fleece flower root, emblic leafflower fruit and stevia. The preparation method comprises the following steps of: heating each medicine with 60 degree corn wine at a ratio of 1:20 to 50-70 DEG C, maintaining the temperature for 3-5 hours, sealing and soaking at normal temperature for 10-15days, and filtering the soaked liquid to separately obtain antler wine, eucommia wine, wolfberry fruit wine, Chinese angelica wine, polygonatum canaliculatum wine, corydalis tuber wine, mint wine, honeysuckle wine, prepared fleece flower root wine, emblic leafflower fruit wine and stevia wine; mixing to obtain a prostate health-care raw wine; and blending the prostate health-care raw wine with distilled water to obtain a prostate health-care wine finished product with alcohol content of 35-45 degree. The common drinking amount of the prostate health-care wine is 20-50 mL every day before bedtime; and the prostate health-care wine can adjust integral function, improve nutrient absorption of a human body, resist and control the generation and development of various prostate diseases and hasthe action of promoting sleeping.

The invention discloses a Chinese medicinal composition for overcoming drug addiction. The Chinese medicinal composition consists of the following medicines in percentage by mass: 30 percent of scorpion, 30 percent of centipede, and 40 percent of stiff silkworm, and the sum of the content of the three medicines is 100 percent; the three medicines are decocted in water; a decoction which is obtained for the first time is taken after dinner or before bedtime, and a decoction which is obtained for the second time is taken by a patient with an empty stomach in the morning next day; and the Chinese medicinal composition has the characteristics of quick response and good curative effect when used for overcoming drug addiction.

An inventive composition for the treatment of hyperhidrosis comprises an active ingredient, namely aluminum chloride in the range of 14.25% to 15.75% by weight and water in the range of about 75% to 80% by weight. The solution of the inventive composition is applied to a body via a pre-soaked towelette by dabbing the towelette over the parts of the body susceptible to excessive sweating. The composition includes a skin protein that binds with the active ingredient to effectively block the pores and sweat glands to control excessive perspiration. The solution of the composition is applied in the evening before bedtime, and immediately after showering in hot water, so that the pores are most receptive to the solution and the composition effectively blocks the pores.

A kit for promoting oral hygiene, and a method for using such a kit are disclosed. The kit may comprise several compositions or a single composition, each of which comprises an effective amount of xylitol. For example, the kit may comprise a chewing gum composition, a morsel composition, a paste-like composition, and an oral rinse composition; or any one of the above compositions; or any combination thereof. It will be appreciated that a novel method for using such a kit for promoting oral hygiene may include: brushing a user's teeth with the paste-like composition comprising at least about 0.05 g to about 0.75 g of xylitol at least in the morning and in the evening, administering at least about 0.75 g of xylitol after consumption of nutrition by chewing a gum composition or by partaking of a morsel composition, and rinsing the user's oral cavity with an oral rinse composition comprising at least about 0.75 g of xylitol at least before bedtime.

Use of a compound having the formula (I) in the preparation of a medicament composition comprising from about 1.0% to about 25% of said compound and a pharmaceutically acceptable vehicle, for topicaladministration to skin of an area of a mammalian subject suffering from hyperhidrosis, before bedtime, such that compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours.

The invention relates to a fast dissolving granulate obtainable by spray-dying of a composition comprising a dry methanolic or ethanolic extract of valerian root, a dry methanolic extract of hop strobiles, optionally a carrier, one or more artificial sweeteners, one or more flavoring agents, optionally an acidifier and water for the treatment of sleep disorders, wherein the said granulate is to be administered upon dissolution in water or an aqueous beverage shortly before bedtime.

The invention discloses a preparation method of a stomach-invigorating cocktail. The preparation method is characterized by comprising the following steps: (1) selecting materials including 38-degree white spirit, milk, codonopsis pilosula, astragalus membranaceus, poria cocos and hawthorn; (2) blending the materials in the step (1) according to a weight ratio of 3:3:1:1:1:2; (3) stirring uniformly, sealing and storing for 10 to 12 days, and inversing three times per day during storage. The preparation method provided by the invention is easy to operate, and is suitable for common families. The prepared cocktail is healthy and nutritious, and can improve sleep quality if drinking before bedtime.

The invention relates to a traditional Chinese medicine pediluvium formula for treating a cough. The traditional Chinese medicine pediluvium formula is characterized by consisting of the following components in weight ratio: 150g of heartleaf houttuynia herbs, 100g of herba asari, and 50g of herba ephedrae. A making and taking method comprises the steps of preparing the medicament in weight ratio, decocting 150g of the heartleaf houttuynia herbs, 100g of the herba asari and 50g of the herba ephedrae with water to obtain a decoction, and using the decoction for pediluvium, so as to achieve the effects of clearing heat, eliminating phlegm, promoting the dispersing function of the lung, and regulating vital energy. The traditional Chinese medicine pediluvium formula is suitable for a cough caused by phlegm heat. The pediluvium is made 30 minutes before bedtime every day, wherein the water temperature is about 40 DEG C, and the pediluvium is used for half an hour. The traditional Chinese medicine pediluvium formula is used for 7 days to form one treatment course. The traditional Chinese medicine pediluvium formula solves the problem that a conventional medicine has great side effects after being used for treatment, and is suitable for treatment of coughs.