61 results about "Glycine Hydrochloride" patented technology

It is provided a pharmaceutical composition stably containing ghrelin or its derivative, which is an endogenous growth hormone secretagogue (GHS) to a growth hormone secretagogue-receptor (GHS-R), comprising a aqueous solution containing the ghrelins having pH range of 2 to 7, wherein the aqueous solution having pH range of 2 to 7 is a buffer solution, especially, glycine hydrochloride buffer, acetate buffer, citrate buffer, lactate buffer, phosphate buffer, citric acid-phosphate buffer, phosphate-acetate-borate buffer or phthalate buffer, and the concentration of the ghrelins in the solution is from 0.03 nmol/mL to 61 μmol/mL.

The invention discloses a bio-based hemodialysis membrane and a preparation method thereof. The hemodialysis membrane is prepared from polylactic acid, laminarin, thiolated chitosan, silk fibroin, sodium ascorbyl phosphate, cellulose acetate, dithiothreitol, stachyose, betulin caffeate, ammonium persulfate, ferulic acid, hydroxyethyl starch, N-benzyl glycine hydrochloride, deoxycholic acid, polyhydroxyalkanoate, hexamethylenediamine, hyaluronic acid, benzoperoxide and dimethyl sulfoxide. According to the prepared hemodialysis membrane, the tensile strength is not lower than 7.0 MPa, the transmittance of urea is higher than 86%, the transmittance of beta2 microglobulin is higher than 66%, the rejection rate of macromolecular protein is higher than 95%, the biocompatibility is good, coagulation, thrombus, inflammation, poisoning and other adverse reactions do not exist, and an application prospect is wide.

The invention relates to an acetate acid free hemodialysis agent of bicarbonate. The hemodialysis agent is composed of constituent A and constituent B, constituent A: sodium chloride 77%-94%, potassium chloride 0%-4%, calcium chloride 2%-6%, magnesium chloride 1%-3%, glycine hydrochloride 3%-10%. constituent B: sodium bicarbonate 65%-100%, sodium chloride 0%-35%.

The invention relates to a glycine and an application of an acid salt thereof in preparation of herbicide-glyphosate, and in particular relates to an application of glycine hydrochloride and glycine methyl ester hydrochloride in preparation of the herbicide-glyphosate.

The invention discloses a method for detecting N-tertbutyl glycyl acyl hydrochloride in tigecycline. The invention further discloses a method for detecting N-tertbutyl glycine hydrochloride in tigecycline. The methods are used for detecting the N-tertbutyl glycyl acyl hydrochloride and the N-tertbutyl glycine hydrochloride in tigecycline, are accurate and reliable in detection result, strong in specificity and short in detection time; and moreover a good separation degree of the N-tertbutyl glycyl acyl hydrochloride and the N-tertbutyl glycine hydrochloride is achieved, so that the possibility in comprehensively detecting the impurities in a tigecycline product, controlling the product quality and ensuring the medicine security is provided.

The invention belongs to the field of medicine and chemical industry, and discloses a preparation method of glucosamine sulfate potassium salt. The preparation method comprises the following steps: adding lactic acid glycine hydrochloride and hydrochloric acid into chitin powder, stirring and mixing, and filtering to obtain a filtrate; heating, preserving heat, dropwise adding hydrochloric acid, stirring, cooling, decoloring the solution, concentrating, washing and drying to obtain glucosamine hydrochloride; adding a potassium sulfate aqueous solution, heating, adding an organic solvent, cooling to 25 DEG C to 35 DEG C, fully reacting, cooling, crystallizing, centrifuging to obtain a white crystal, and drying to obtain the glucosamine sulfate potassium salt. According to the preparation method, the high-purity glucosamine hydrochloride is obtained firstly, then the potassium sulfate aqueous solution is added to prepare the glucosamine sulfate potassium salt, and the glucosamine sulfatepotassium salt of which the purity reaches up to 99.95% or more is obtained through crystallization purification and separation, so that the whole technical process is simple, low in cost, environmentally-friendly and economical, and the preparation method is suitable for large-scale popularization and application.

The invention belongs to the field of pharmaceutical chemicals and discloses a method for preparing glucosamine sulfate and sodium chloride double salt. The preparation method comprises the followingsteps: adding lactic acid glycine hydrochloride and hydrochloric acid into chitin powder, performing stirring and mixing, and performing filtering to obtain filtrate; heating the filtrate, performinginsulation, dropwise adding hydrochloric acid into the solution, stirring the mixture, cooling the mixture, and performing decoloring, concentrating, washing and drying to obtain glucosamine hydrochloride; adding a sodium carbonate aqueous solution into the glucosamine hydrochloride, performing heating, adding acetone into the mixture, performing cooling and stirring, adding sulfuric acid into themixture, performing stirring, cooling completely reacted materials to 5-15 DEG C, performing crystallization, drying centrifuged crystals to obtain the glucosamine sulfate and sodium chloride doublesalt. The method has a safe and controllable production flow, the glucosamine sulfate and sodium chloride double salt has high purity and high stability, the finished product has high quality, and thedefects that pure glucosamine sulfate has high moisture absorption, is not stable and is not suitable for medicinal application can be overcome.

The invention provides juice jelly with effects of beautifying and losing weight. The juice jelly is prepared from the following raw materials in parts by weight: 16 to 22 parts of mixed fruit juice, 1 to 5 parts of gelatin, 1 to 5 parts of carrageenan, 0.5 to 4 parts of L-methionylglycine hydrochloride, 0.5 to 2 parts of calcium lactate, 5 to 12 parts of sugar and 60 to 75 parts of water. The invention belongs to the technical field of food processing; the juice jelly does not contain a preservative and is high in content of fruit juice; the prepared juice jelly has the advantages of strong greengage flavor, good shape stability, good mouthfeel, easiness in digestion and absorption, long shelf life and the like; the juice jelly has the effects of beautifying and losing weight, and is good in safety.

The invention discloses a preparation method for a low temperature resistant geogrid. The preparation method comprises the following operating steps: (1) preparing a low temperature resistant additive, namely, placing aluminium oxide, 3-hydroxyl-1-adamantaneacetic acid, N,N-di(octyl aminoethyl) glycine hydrochloride, titanium dioxide and tungsten disulphide into a ball grinding mill, mixing at a high speed to prepare the low temperature resistant additive; (2) mixing HDPE (High-Density Polyethylene), an antioxidant DLTP (Dilauryl Thiodipropionate), tetrabromo bisphenol S, heptamethylnonane and dinonyl phthalate, placing the mixture in a high-speed mixing machine, mixing at a high speed, adding the low temperature resistant additive into the high-speed mixing machine, and continuing mixing; (3) placing the mixture which is obtained in the step (2) into an extruding machine for melting and extruding to prepare a plate; (4) punching the plate to obtain mesh holes through a punching machine; (5) performing unidirectional stretching and subsequent further horizontal stretching on a porous plate after the porous plate is heated through a preheating device so as to form a unidirectional or bidirectional stretched grid. The geogrid prepared by the preparation has good low temperature resistance, and can work normally in a low temperature environment and ensure the quality of a product.

The invention belongs to the field of pharmaceutical chemicals, and discloses a purification and separation method of N-acetyl-D-glucosamine. The purification and separation method of the N-acetyl-D-glucosamine comprises the following steps: adding lactic acid glycine hydrochloride and hydrochloric acid into chitin powder, performing mixing, and performing filtering to obtain a filtrate; performing heating, adding hydrochloric acid dropwise, performing stirring, performing cooling, and performing decoloring to obtain D-glucosamine hydrochloride; adding an ethanol solution of sodium ethoxide, and performing filtering to obtain a free D-glucosamine solution; adding acetic anhydride to obtain a solution containing the N-acetyl-D-glucosamine; and performing concentration, performing cooling, performing crystallizing, performing filtration to obtain an N-acetyl-D-glucosamine crude product, performing soaking by using absolute ethyl alcohol, performing stirring, performing filtration, and performing drying to obtain the high-purity N-acetyl-D-glucosamine. According to the method, the N-acetyl-D-glucosamine with the purity of 99.95% or above can be obtained, the technological process is simple, the post-treatment is easy to realize, the cost is low, the used alcohol solvent can be recycled, and the method is environmentally friendly, economical and suitable for large-scale promotion and application.

The invention discloses a method for preparing a flame-retardant flexible freight bag. The method comprises the following operating steps: (1) uniformly mixing melamine cyanurate, sodium molybdate dihydrate, glycine N-bis(octylaminoethyl)hydrochloride and polyvinyl imidazol, adding the mixture into a ball mill, performing ball milling for 2-3 hours, and drying to obtain a flame retardant; and (2)uniformly mixing polypropylene resin, the flame retardant, N-acetylthiourea and mixed additives, adding the mixture into an extruder, performing melt spinning, braiding into a suspender and base clothby a weaving machine, cutting, and sewing, thereby obtaining the flame-retardant flexible freight bag. The preparation method of the flame-retardant flexible freight bag provided by the invention issimple to operate and low in cost, and the prepared flame-retardant flexible freight bag has excellent mechanical property and high filament strength, does not cause a breakage phenomenon after braided molding, particularly has excellent flame-retardant property, and can prevent fostering of the fire when the fire happens.

The invention provides a preparation method of 2-n-butyl-4-chloro-5-formylimidazole. The preparation method comprises the following steps of using pentanimidamide hydrochloride and tert-butyl glycine hydrochloride as initial raw materials to react, so as to obtain (1-imido amyl)tert-butyl glycinate; performing deprotection, ring closing, chlorinating and vilsemier reaction, and recrystallizing, so as to obtain the 2-n-butyl-4-chloro-5-formylimidazole. The preparation method has the advantages that the price of raw materials is low, the obtaining is easy, the cost is low, the content of impurities is low, and the purity is high; the organic solvent used in the preparation process can be recycled, the pollution is little, the environment-friendly effect is realized, and the preparation method is suitable for industrialized large-scale production.

The invention discloses a treatment process for leftover materials generated in a glycine ethyl ester hydrochloride preparation process. The process comprises the steps of reacting glycine with absolute ethyl alcohol in the presence of hydrogen chloride, crystallizing and separating a reaction product to obtain mother liquor, and adding alkali to hydrolyze the mother liquor. The treatment method provided by the scheme for the leftover materials generated in the glycine ethyl ester hydrochloride preparation process is particularly suitable for treating the leftover materials after repeated treatment and recovery. Through the treatment, residual glycine ethyl ester hydrochloride, glycine hydrochloride and other hydrolyzable byproducts are hydrolyzed into glycine and the like by adding alkali, then the pH value is adjusted to be close to an isoelectric point of glycine, glycine is separated out, glycine is obtained through separation, and ethanol generated through hydrolysis is recycled through distillation. By means of the scheme, the generation amount of leftover solid waste can be greatly reduced.