Preparation method of ethyl chitosan film

A technology of ethyl chitosan film and ethyl chitosan, applied in the field of preparation of ethyl chitosan film, can solve the problem of low mechanical strength of ethyl chitosan film

Inactive Publication Date: 2017-02-08
QINGDAO UNIV OF SCI & TECH
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the preparation process of ethyl chitosan film mostly follows the technology of chitosan film, based on the existing patents (such as CN03118535.5, CN201410025894.X, CN201310492147.2) about the preparation of chitosan film. The mechanical strength of ethyl chitosan membranes is very low, therefore, how to improve the membrane technology is the key issue to prepare high performance ethyl chitosan membranes

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Prepare 50g of 1.5% glycine hydrochloride aqueous solution, completely dissolve 0.75g of ethyl chitosan (with a degree of substitution of 8%) in the above solvent to prepare a 1.5% concentration of ethyl chitosan film-making stock solution. Press filtration, static defoaming, rotating coating on glass plate, constant temperature 40℃ and constant humidity 50% drying, soaking in absolute ethanol solution for 2.5h to remove the film, distilled water washing until neutral, and constant temperature 40℃ constant humidity 50% drying, etc. By operation, a transparent ethyl chitosan film was obtained with a thickness of 1.52 μm, a breaking strength of 181 MPa, a breaking elongation of 3.97%, and an initial modulus of 4.52 GPa.

Embodiment 2

[0016] Prepare 50 g of a 2.0% glycine hydrochloride aqueous solution, completely dissolve 1.25 g of ethyl chitosan (degree of substitution 12%) in the above solvent to prepare a 2.5% concentration of ethyl chitosan film stock solution, and then extrude Press filtration, stand for defoaming, spin coating on glass plate, constant temperature 40℃ and constant humidity 50% drying, soaking in absolute ethanol solution for 3.5h to remove the film, distilled water washing until neutral, and constant temperature 40℃ constant humidity 50% drying, etc. Through operation, a transparent ethyl chitosan film with a thickness of 1.82 μm, a breaking strength of 187 MPa, a breaking elongation of 4.21%, and an initial modulus of 4.77 GPa was obtained.

Embodiment 3

[0018] Prepare 50 g of a 3.0% glycine hydrochloride aqueous solution, and completely dissolve 1.0 g of ethyl chitosan (with a degree of substitution of 16%) in the above solvent to prepare a 2.0% ethyl chitosan film-making stock solution. Press filtration, stand deaeration, spin coating on glass plate, constant temperature 40℃ and constant humidity 50% drying, immersion in absolute ethanol solution for 3.0h, peel off the film, wash with distilled water to neutral, and constant temperature 40℃ and humidity 50% drying, etc. By operation, a transparent ethyl chitosan film was obtained, with a thickness of 1.92 μm, a breaking strength of 192 MPa, a breaking elongation of 3.85%, and an initial modulus of 4.65 GPa.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Thicknessaaaaaaaaaa
Breaking strengthaaaaaaaaaa
Initial modulusaaaaaaaaaa
Login to view more

Abstract

The invention discloses a preparation method of an ethyl chitosan film. The preparation method comprises fully dissolving self-made ethyl chitosan in a glycine hydrochloride aqueous solution with a concentration of 1-5% to obtain an ethyl chitosan stock solution with a concentration of 1-5wt%, and orderly carrying out extruding filtration, standing deaeration, spin-coating on a glass plate, drying at a constant temperature of 40 DEG C at constant humidity of 50%, immersion in anhydrous ethanol for 1-5h, film uncovering, film washing until pH of 7 and drying at a constant temperature of 40 DEG C at constant humidity of 50%. The film has thickness of 1.5-2 microns, breaking strength greater than or equal to 180MPa, breaking elongation greater than 3.7% and initial modulus greater than 4.5GPa. The film can be used as an anticoagulation material, a bone repair material and wound dressing.

Description

Technical field [0001] The invention belongs to the technical field of film material preparation, and specifically relates to a preparation method of ethyl chitosan film. The method not only expands the types of chitosan film, but also overcomes the solvent in the current preparation process of chitosan film. Disadvantages such as volatile, serious pollution, and large amount of waste treatment. Specifically, the high-molecular-weight homemade ethyl chitosan is used as the raw material, and the aqueous solution of glycine hydrochloride is used as the solvent to prepare a film-making solution with a suitable concentration; a homogenizer is used for spin coating, and then the film is soaked and removed at a constant temperature. Constant humidity drying and other steps, finally obtain the ethyl chitosan film. Background technique [0002] Chitin is a high-molecular biomass resource, which is widely present in marine organisms such as shrimps, crabs and other arthropods, mollusks a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C08J5/18C08L5/08A61L27/20A61L27/60A61L15/28A61L26/00A61K47/36
CPCA61K47/36A61L15/28A61L26/0023A61L27/20A61L27/60C08J5/18A61L2430/02C08J2305/08C08L5/08
Inventor 于世涛李露刘仕伟刘福胜解从霞曹兴
Owner QINGDAO UNIV OF SCI & TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap