163 results about "Diazole" patented technology

Disclosed is an electroluminescent device comprising a light-emitting layer including a light emitting material that contains an organometallic complex comprising (1) a metal selected from the group consisting of Ir, Rh, Os, Pt, and Pd and (2) a diazole group ligand wherein the ligand has a fused aromatic ring group including a nitrogen of the diazole as a bridgehead nitrogen. The device provides useful light emission.

The invention provides a combination comprising (or consisting essentially of) an ancillary compound and a compound of the formula (I): or salts, tautomers, solvates and N-oxides thereof; wherein: R1 is 2,6-dichlorophenyl; R2a and R2b are both hydrogen; and R3 is a group: formula (A) where R4 is C1-4 alkyl. The combinations have activity as inhibitors of CDK kinases and inhibit the proliferation of cancer cells.

A method of improving the yield and vigor of an agronomic plant involves treating plants such as soybeans and corn and / or their propagation material with a composition that includes an active agent, such as a diazole fungicide, a triazole fungicide, or a strobilurin-type fungicide, which has the capacity to improve the yield and / or the vigor of the plant in the absence of pest pressure by fungal plant pathogens. Formulations that contain a diazole fungicide, a triazole fungicide, or a strobilurin-type fungicide, and plants and plant propagation material, such as seeds, which have been treated by the novel method are also described.

Highly efficient ZnS:Mn phosphors can be obtained by using triazole or diazole compounds during homogeneous precipitation in aqueous medium. Coated layers containing such phosphors can be incorporated in Thin Film Inorganic Light Emitting Diodes.

Novel thiadiazole compounds are provided, which are effective as proton pumps inhibitors, useful in treating peptic ulcers by inhibition of the proton pump enzyme H+ / K+-ATPase. The compounds are 3-substituted 1,2,4-thiadiazolo [4,5- alpha ]benzimidazole and 3-substituted imidazo[1,2-d]-1,2,4-thiadiazoles corresponding to the general formula: where X and Z either represent an optionally substituted benzene ring fused to the diazole nucleus, or represent a variety of independent chemical groupings (hydrogen, lower alkyl, halo, etc.) and Y is selected from a wide range, e.g. heterocyclics and carbonyl groups.

Disclosed is an electroluminescent device comprising a light-emitting layer including a light emitting material that contains an organometallic complex comprising (1) a metal selected from the group consisting of Ir, Rh, Os, Pt, and Pd and (2) a diazole group ligand wherein the ligand has a fused aromatic ring group including a nitrogen of the diazole as a bridgehead nitrogen. The device provides useful light emission.

Highly efficient ZnS:Mn phosphors can be obtained by using triazole or diazole compounds during homogeneous precipitation in aqueous medium. Coated layers containing such phosphors can be incorporated in Thin Film Inorganic Light Emitting Diodes.

In order to provide an electro luminescent element with high heat endurance and low crystallinity using functional molecules having functions of hole transporting, luminescence, and electron transporting, an electro luminescent element according to the present invention comprises one or more organic compound layers 14 between a first electrode 12 and a second electrode 16, wherein at least one of the organic compound layers 14 is a condensed ring compound derivative represented by the following chemical formula,in which A1 and A2 represent substituents, B1 through B6 represent directly connected or di functional substituents, and R1 and R2 represent functional units having each of the functions of hole transporting, luminescence, and electron transporting, such as triphenylamine, coumarin, and oxadiazole derivative.

Acridine containing cisplatin compounds have been disclosed that show greater efficacy against cancer than other cisplatin compounds. Methods of delivery of those more effective cisplatin compounds to the nucleus in cancer cells is disclosed using one or more amino acids, one or more sugars, one or more polymeric ethers, C1-6alkylene-phenyl-NH—C(O)—R15, folic acid, αvβ3 integrin RGD binding peptide, tamoxifen, endoxifen, epidermal growth factor receptor, antibody conjugates, kinase inhibitors, diazoles, triazoles, oxazoles, erlotinib, and / or mixtures thereof; wherein R15 is a peptide.

Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.

The invention provides triazolothiadiazole containing derivatives, a synthesizing method thereof and application thereof. The invention relates to 1,2-diazole containing heterocyclic compounds, which have the following chemical structural general formula. The invention discloses a chemical structure and a synthesizing method of the compounds, a using method and application of the triazolothiadiazole containing derivatives for resisting TMV viruses, a using method and application in inhibiting the growth of plant pathogenic fungi, and application of the combination of the compounds, the conventional commercial anti-virus medicaments and bactericides, herbicide and insecticide in preventing and controlling diseases, pests, weeds and virus diseases of the agriculture, forestry and gardening.

The invention belongs to the field of organic photoelectric materials, and discloses a regular polymer containing monofluorine-substituted benzo-hetero[1,3]diazole, a preparation method of the regular polymer and application of the regular polymer in the field of organic photoelectric technologies. The structural formula of the polymer is shown as the first formula (please see the formula in the description), wherein x, y and z are separately independent and represent integers ranging from 0 to 5, n represents a positive integer ranging from 3 to 100,000, X1, X2 and X3 are separately independent and are selected from O or S or Se or Te or N-R or R-C-R or R-Si-R or R-Ge-R or R-Sn-R, R represents straight chains or branch chains or circular alkyl chains of C1-C30, R1, R2, R3 and R4 are separately independent and are selected from hydrogen, an alkyl group with 1-30 carbon atoms and an alkoxy group with 1-30 carbon atoms, an alkenyl group, an aryl group, a carboxyl group, a carbonyl group, an amino group, a cyano group, a nitryl group, an ester group, halogen and a halogenated alkyl group, and Ar is selected from a non-substituted or substituted electron-deficient conjugate unit group, an electron-rich conjugate group and a conjugate unit group formed by the units. The polymer can be applied to organic solar cell devices.

The invention provides a method for preparing and synthesizing a derivative containing s-triazolothiadiazole and an application thereof. The invention relates to a heterocyclic compound containing 1,2-diazole, and the compound has the following chemical structural formula: the invention discloses the chemical structure and the synthesis method of the compound, a use method and an application of the s-triazolothiadiazole derivative in resisting TMV virus and a use method and an application in inducing the tobacco anti-TMV virus; the invention also discloses a use method and an application the compound in killing insects and inhibiting the growths of plant pathogenic fungi and simultaneously discloses a combined application of the compound and the prior merchandizing antiviral agents, germicides, herbicides and pesticides in preventing viruses and inserts in agriculture, forestry and gardening.

The invention relates to the technical field of medicines, in particular discloses a levorotatory fluoroquinolone C3 diazole methyl sulfide quaternary ammonium salt, and further discloses a preparation method and application of the levorotatory fluoroquinolone C3 diazole methyl sulfide quaternary ammonium salt in the pharmaceutical field simultaneously. The chemical structural formula of the levorotatory fluoroquinolone C3 diazole methyl sulfide quaternary ammonium salt is represented by a general formula I: the general formula I is described in the specification. The levorotatory fluoroquinolone C3 diazole methyl sulfide quaternary ammonium salt provided by the invention has stronger in-vitro cytotoxicity effect on experimental leukemia cancer cell strains and stronger anti-tumor activity, and can be mixedly prepared into anti-tumor medicines with human body acceptable acidic salts or pharmaceutical carriers.

The invention discloses a low-torque arc-proof composite fabric and a preparation method thereof. The composite fabric sequentially comprises a flame-retardant heat-insulating layer, a flame-retardantadhesive connecting layer and an antibacterial heat-resistant layer from outside to inside, wherein the flame-retardant heat-insulating layer mainly comprises, by weight, the following components: 10-50 parts of blue essence flame-retardant adhesive, 20-40 parts of vinylon, 10-30 parts of aramid fiber 1313, 5-15 parts of aramid fiber1414, 10-30 parts of polyimide and 1-3 parts of conductive fiber, the antibacterial heat-resistant layer is mainly formed by blending 20-60 parts of silicon-nitrogen flame-retardant adhesive, 20-40 parts of vinylon, 10-30 parts of polyaryloxy diazole fiber, 10-30parts of aramid fiber1313 and 1-3 parts of conductive fiber, the yarn twist degree of the antibacterial heat-resistant layer is 60-65 twist / 10 cm. The low-torque arc-proof composite fabric obtained bycompounding a plurality layers of structures has good arc-proof and anti-explosion performances to the outside and good soft comfort and air permeability to the inside under the condition of being light and thin.

A pigment grade corrosion inhibitor and a method of forming the inhibitor is disclosed. The inhibitor is comprised of a host species comprised of an inorganic compound having a layered structure and a guest species comprised an anionic species of a weak acid. The host species is preferably a double hydroxide having a structure of: [M(II)1-xM(III)x(OH−)2] [An−x / n.y H2O], where M(II) is a divalent metal cationic species, M(III) is a trivalent metal cationic species, and An− is an anionic species, preferably with the species present in a range of: 0.2≦M(III) / (M(II)+M(III))≦0.4. The guest species include: ortho-phosphoric, pyrophosphoric, tripoly-phosphoric, polyphosphoric acid; mono- and di-alkyl or aryl-esters of ortho-phosphoric and pyrophosphoric acid; metaphosphoric, trimeta-phosphoric, poly-metaphosphoric acid; phosphorous (phosphonic) acid; derivatives of phosphonic acid; alkyl and aryl esters of thio-phosphoric and dithio-phosphoric acid; molybdic, phospho-molybdic, silico-molybdic acid; boric acid; cyanamidic acid; nitrous acid; derivatives of thio- and dithiocarbonic acid, including o-alkyl esters; derivatives of dithiocarbamic acid, including N-alkyl dithiocarbamates; pyrrolidinecarbodithioic acid; thio-organic compounds functionalized with at least one —SH group of acidic character, including: 2,5-dimercapto-1,3,4-thiadiazole (DMTD), 2,4-dimercapto-s-triazolo-[4,3-b]-1,3-4 thiadiazole, trithiocyanuric acid (TMT), and dithiocyanuric acid, various N—,S— and N,N—, S,S— and N,S-substituted derivatives of the above DMTD and TMT compounds; various S-substituted derivatives of trithiocyanuric acid; dimer and polymer derivatives of the above DMTD and TMT compounds, including 5,5′ dithio-bis (1,3,4 thiadiazole-2(3H)-thione or (DMTD)2, and (DMTD)n, polymers of DMTD and (TMT)2, dimers and polymers of TMT; various combinations of all the above; soluble salts of DMTD and TMT; poly-ammonium salt of DMTD or (DMTD)n and TMT formed with polyamines; mercapto-benzothiazole, mercapto-benzoxazole, mercapto-benzimidazole, and combinations, thereof; di- and poly-mercapto compounds, including: di-mercapto derivatives of thiophene, pyrrole, furane, diazoles, and thiadiazoles; di- and tri-mercapto derivatives of pyridine, diazines, triazines, benzimidazole, and benzothiazole, including dimercaptopyridine, 2, 4-dithiohydantoine, and 2,4,-dimercapto-6-amino-5-triazine; and carboxylic and di-carboxylic acids, including ascorbic, salicylic acid, phthalic acid, nitro-phthalic acid, succinic acid, and derivatives of succinic acid, including 1-(benzothiazol-2-ylthio)succinic acid.

A method for preparing red benzimidazolone organic dyestuff includes applying diazotization process to carry out diazotization for substituted aromatic amine and aminobenzenesulfonic acid separately for obtaining relevant diazoles solutions, mixing the two diazols, using mixed diazols to couple with coupling composition for obtaining coupled material in mixed crystal form and producing final dyestuff product through pigmenting.

Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.

A lithium ion polymer electrolyte membrane and its preparation method and application relate to that field of solid electrolyte. The preparation method of the lithium ion polymer electrolyte membraneof the embodiment of the invention is that the sulfonated poly (phosphodiazole) stock solution is solidified to obtain the sulfonated poly (phosphodiazole) film, and the sulfonated poly (phosphodiazole) film is reacted with lithium salt to obtain the poly (phosphodiazole) sulfonate lithium electrolyte membrane; and the sulfonated poly (phosphodiazole) film is solidified to obtain the sulfonated poly (phosphodiazole) film; or preparing lithium poly (1, 2-diazole sulfonate) solution by sulfonated poly (1, 2-diazole sulfonate) stock solution and lithium salt, and coagulating to form membrane to obtain poly (1, 2-diazole sulfonate) lithium electrolyte membrane. The method is simple and easy to operate. The poly (phthalazinesulfonic acid) lithium electrolyte membrane of the embodiment of the invention has high room temperature ionic conductivity, good electrochemical stability, flame retardancy and excellent heat resistance; a lithium ion polymer electrolyte membrane accord to an embodimentof that present invention is used as a solid-state electrolyte membrane of a solid-state lithium battery.

The invention belongs to the field of polymer semiconductor materials, and discloses a polymer semiconductor containing a bipyridine diazole derivative receptor and a preparation method and application thereof. A structure of the polymer semiconductor is shown in a formula (I), and the preparation method comprises the following steps: (1) reacting 2-tributyltin-4-alkylthiophene with a dibromobenzimidazole derivative to prepare an intermediate a; (2) reacting the compound a with a bis-butyltin b to obtain a compound c; (3) performing a reaction on the compound c and N-bromosuccinimide to obtainM1; and (4) performing a palladium-catalyzed coupling reaction on the M1 and (E)-bis1,2-(tri-n-butyltin)ethylene to obtain the final product. According to the invention, the synthetic route is simpleand high-efficiency, the raw materials are easy to obtain, the costs are low, the universality is high and the repeatability is good, and a field effect transistor prepared by using the polymer semiconductor as an active layer obtains outstanding bipolar transmission characteristics, and has wide market prospects.

The invention discloses a metal-organic coordination polymer with the organophosphorus hydrolase activity and a preparation method and application thereof. The structural unit of the polymer is [Zn(L1)0.5(L2)0.5].3DMF, wherein L1 represents 1,3-bis[di(2-diazole)-hydroxymethyl]phenyl, L2 represents 3,3',5,5'-biphenyl tetracarboxylic acid ions containing four carboxyls with no proton, DMF represents N,N-dimethyl formamide, and two DMF solvent molecules are out of order. The polymer belongs to a monoclinic system and a C2 / c space group. The polymer is synthesized under the low temperature through a solvothermal method, substrate organophosphorus can be effectively hydrolyzed, when pH is equal to 9.0, the ethyl paraoxon hydrolysis activity of the 0.1 mg / mL polymer is about 28 times the hydrolysis activity with no polymer, the Vmax of ethyl paraoxon hydrolysis reaction catalysis is 0.75 micro-mol / L.min, and the Km is 2.5 mmol / L. The polymer has the potential application value for constructing biometric sensors for degrading organophosphorus poison and detecting organophosphorus.

The invention discloses a fluorescent probe based on 2-styryl indole salt type derivative long-wave emission for distinguishable detection on Cys / Hcy and application of the florescent probe. The structural formula of the fluorescent probe L is shown in the specification. The fluorescent probe L is prepared from a 2-styryl indole salt as a substrate together with 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole and triethylamine through gentle and simple reaction and has long-wave emission. The fluorescent probe L is simple in synthesis step, long in long-wave emission, short in response time, only capable of recognizing Cys / Hcy in a water-containing medium, capable of implementing distinguishable detection on Cys / Hcy, good in sensitivity and applicable to detection for purposes of non-disease diagnosis and non-disease treatment in cells.

The invention discloses 2, 5-di (rhodamine B-9'-(2''-benzoyl) radical)-1, 3, 4-diazole fluorescent stain compound I and a preparation method and application thereof. The compound I has excellent dissolubility in water, emits strong fluorescent light and can be applied to being biological stain, namely cell stain, and water solution of the compound I cannot suddenly extinct in fluorescence spectrum in a range of the pH (potential of hydrogen) value from 2 to 10. The compound I can be prepared from rhodamine B and phosphorus oxychloride directly or can be prepared through intermediate compound IIN and N'-double-rhodamine B hydrazine. The invention further discloses the application of the structural formula I serving as biological stain, namely cell stain.

The invention discloses a lipid droplet targeting fluorescent probe and a synthesis method and application thereof. The synthetic method comprises the following steps of enabling a triphenylamine phenylboronic acid compound and 4-chloro-7-nitrobenzo-2-oxa-1, 3-diazole to react for 10-50 h in an organic solvent at the temperature of 60-120 DEG C under the protection of inert gas and the action of acatalyst and alkali, cooling the reaction product to the room temperature, adding dichloromethane, filtering, decompressing to remove the solvent, separating and purifying the product, and drying theproduct. The fluorescent probe provided by the invention has no fluorescence in an aqueous solution, basically has no fluorescence in an organic solvent, has very strong fluorescence in grease, and can specifically target lipid droplets in cells.

The invention discloses perylene tetracarboxylic carboxylic ester group polymer acceptor materials and application thereof to a solar battery. The materials include a structure as refined in formula 1, in the formula 1, M is diazosulfide, dithienyl diazosulfide, selenole, dithienyl selenole, diselenium thiophene selenole, thiophene, dithiophene, terthienyl, benzene, selenophen, diselenide thiophene, terselenide thiophene, thiophene thiophthene, benzo dithiophene, benzo ditellurium thiophene, benzo ditellurium thiophene, or one of derivatives made on the basis of the compounds. R is a linear chain with more than four carbon atoms, a branched chain or an alkyl chain containing different heteroatoms. N is a natural number of 1-1000. By introducing comonomer M on the perylene ring skeletons 1, 7 positions, the level structure of polymer materials can be adjusted, and at the same time, optical property is improved, and use ratio of the materials to light is enhanced. By introducing R, dissolubility of the polymer materials can be adjusted, and utilization of a solution processing technology with low cost is facilitated. The materials can be applied to the field of organic optoelectronics.

The invention discloses a thiadiazole-containing oxadiazole compound shown in a formula (I), a preparation method of the compound and application of the compound to control of barnyard grass and rape. The compound is a novel compound with herbicidal activity, and provides a foundation for research and development of novel pesticides.

Laevo isomer and dextroisomer of alpha-substituted 2-methyl-5-nitrodazole-1-ethanol derivative, its production, medicinal composition containing the derivative or its solvent or accepted salt and use for preparing anti-anaerobe medicine are disclosed.

The invention discloses an environment-friendly plastic adhesive and a preparation method thereof. The adhesive comprises the following components in parts by weight: 5-8 parts of rosin-based hyperbranched epoxy resin, 3-5 parts of epoxidized SBS, 4-7 parts of filler, 12-20 parts of allyl furoate / N-vinyl caprolactam / N-trihydroxymethyl methacrylamide / N-(4-cyano-3-trifluoromethylphenyl)methacrylamide / trifluoroethyl methacrylate copolymer, 3-5 parts of isocyanate group ionized modified 2,5-bis(diethylamino)phenyl-1,3,4-diazole, 0-0.3 part of dibutyltin dilaurate and 70-80 parts of a mixed solvent. The invention also provides a preparation method of the environment-friendly plastic adhesive. The environment-friendly plastic adhesive provided by the invention is high in bonding strength, good in environmental protection property, durability and aging resistance, fast in curing, high in reliability and good in weather resistance and moisture resistance.

The invention provides a preparation method and application of a pH fluorescence probe. A novel fluorescence probe CM-BHNBD is designed, and is from NBD(4-nitrobenzene-2-oxalic acid-13-diazole); the fluorophore intracellular mitochondria / membrane acidification monitoring can be realized; when the method is applied to pH detection in a biological sample, the advantages of good response performance, high data accuracy, good reproducibility, high precision and the like are realized; the implementation feasibility is high.