The invention provides a
prussian blue nano particle with high photo-thermal performance and of a
manganese-doped hollow structure and a preparation method of the
prussian blue nano particle, belongs to the field of nanometer material preparation and
biomedicine and aims to solve the problems that existing the photo-thermal performance and
biosecurity of an existing
manganese-doped
prussian blue nano particle are in need of improvement, the synthesis process is complex, and the cost is high. The preparation method includes the steps that surface protectant and
potassium ferricyanide are added to an acid solution,
manganese salt is added, and a heating reaction is conducted; 2,
vacuum drying is conducted after washing is conducted; 3, the acid solution, the surface protectant and a manganese-doped
solid prussian blue nano cubic sample are mixed, and the heating reaction is conducted after dispersing is conducted; washing is conducted, a blue porous Mn-HPB nano cubic material is obtained, and
vacuum drying is completed. The prussian blue nano particle with high photo-thermal performance and of the manganese-doped hollow structure is simple in preparation process and high in
controllability, the obtained nano material is uniform in particle
diameter and good in dispersing property, and long-term and stable existence is achieved; excellent
biosecurity is achieved; a higher photo-
thermal effect and photo-thermal conversion efficiency are achieved, and the prussian blue nano particle and the preparation method are used for photo-
thermal treatment of tumors.