The invention discloses an engine fuel cleaning and saving agent and a usage method thereof, belonging to the technical field of fuel additives. The engine fuel cleaning and saving agent is characterized in that the components in percentage by mass are as follows: 3.6%-12% of oil hydrotropy cleaning agent, 0.5%-5% of surface active agent, 19.4%-45% of petroleum ether solvent, 10%-25% of megilp, 4%-12% of low boiling point solvent, 3%-13% of pulverization accelerant, 11%-20% of oxygenate and 1%-13.5% of antidetonant; the oil hydrotropy cleaning agent is a mixture of oleic acid and mixed amine of which the mass ratio is (4-8):(3-6), and the mixed amine is a mixture of two or more compounds selected from ethanediamine, triethylamine, ethanol amine, triethanolamine or cyclohexylamine at any ratio. The fuel cleaning and saving agent is applicable to fuel used on various engine vehicles, is convenient to use and less in use amount, and can exert effect immediately after being added, and the power of an engine can be improved rapidly. The oil saving rate is high, the engine noise is remarkably reduced, and discharge of black smoke and harmful gas is reduced.