48results about How to "The polymerization process is controllable" patented technology

The invention relates to a multi-responsive polymer nanocarrier with a rapid cell penetrating characteristic. The nanocarrier is formed by self-assembling of a multi-responsive amphipathic triblock copolymer, the nanocarrier adopts an onion structure sequentially comprising an acid-responsive PLLA core, cyanine molecules with a near infrared absorption characteristic, a hydrogen-peroxide-responsive PPI (polyphenyl isocyanide) intermediate layer and a left-handed spiral hydrophilic PPI hydrophilic chain from inside to outside sequentially, wherein the structure of the multi-responsive amphipathic triblock copolymer is shown in the general formula in the specification, R1 is a group with stimulation responsiveness, and R2 is a chiral PEG hydrophilic chain; x ranges from 20 to 50, y ranges from 20 to 50, and z ranges from 30 to 80. The multi-responsive polymer nanocarrier can be used for transporting hydrophobic dye molecules and medicine molecules, can rapidly and efficiently penetrate cell membranes, has multiple stimuli-responsiveness, realizes programmable controlled release of medicines and has a chemical-photothermal collaborative treatment characteristic.

The purpose of the invention to provide a polymeric acid solution thickener. The thickener has excellent resistance to a high temperature and shearing, and can meet high temperature and deep well construction requirements. The ternary copolymeric acidified fracturing thickener obtained in the invention can be used for thickening an acid solution with the hydrochloric acid concentration of 5-28%, the apparent viscosity of the thickener at room temperature is 100 mPa.s or above, the viscosity retention rate at 90 DEG C still reaches 60% or above, the viscosity at 110 DEG C can still reach 30 mPa. s or above, and the thickener has good thickening and temperature resisting performances. Compared with conventional preparation technologies, a technology disclosed in the invention has the advantages of high production efficiency, simplicity, mild production conditions, easiness in control of the polymerization process, great reduction of the production cost, and easiness in industrial promotion; and the above product has the advantages of good solubility, convenience in transportation, and good application prospect.

The invention discloses L-carnitine molecularly imprinted microspheres with a core-shell structure and a preparation method thereof, and relates to the field of intelligent high polymer materials. According to the invention, L-carnitine is taken as a template molecule and methacrylic acid is taken as a functional monomer, and the L-carnitine molecularly imprinted microspheres with the core-shell structure are prepared through reversible addition-fragmentation chain transfer and free radical polymerization in combination with the surface molecular imprinting technology; the preparation method of the L-carnitine molecularly imprinted microspheres with the core-shell structure comprises the following steps of: 1, preparing nano SiO2 microspheres by a Stober method; 2, performing surface activation on the nano SiO2 microspheres; 3, performing surface benzylation on the nano SiO2 microspheres; 4, synthesizing an RAFT (Reversible Addition-Fragmentation Chain Transfer Polymerization) reagent on the surface of the nano SiO2 microspheres; 5, preparing the L-carnitine molecularly imprinted microspheres with the core-shell structure; and 6, eluting the imprinted template molecules. The L-carnitine molecularly imprinted microspheres with the core-shell structure has the advantages of simple process, low cost, convenience in industrial popularization and application, and the like; the obtained imprinted microspheres have good adsorbability and selectivity for L-carnitine molecules, and can be applied to separating out carnitine enantiomers.

The invention discloses a preparation method of a polyester-polycarbonate-polyester multi-block copolymer, belonging to the technical field of polymer materials. In the present invention, the multi-block polymerization is accomplished by the "one-pot method", that is, the Bronsted acid catalyst sequentially catalyzes the ring-opening polymerization of cyclic lactones and cyclic carbonates, and then puts in a preset relative acid excess tertiary amine (R3N: ), wherein the acid in the system forms the conjugate acid R3N+-Hδ+ of the base itself as a hydrogen bond donor, and the excess base acts as a hydrogen bond acceptor, and the bifunctional catalyzes the ring-opening of the lactide that is finally put into Polymerization to finally synthesize polyester‑polycarbonate‑polyester triblock copolymers. The invention has the following advantages: the structure of the catalyst is simple and easy to obtain, the reaction is mild and efficient, the "one-pot method" is easy to operate, the whole polymerization reaction is active, the molecular weight of the polymer is controllable and the molecular weight distribution is narrow.

The invention discloses a restricted access type chiral chromatography MC (monolithic column) as well as a preparation method and an application thereof. The preparation process of the restricted access type chiral chromatography MC comprises steps as follows: (1), a framework of the chromatography MC is prepared with an RATRP (reverse atom transfer radical polymerization) method; (2), beta-CD (beta-cyclodextrin) is modified on the framework of MC to serve as a chiral selector; (3),DATRP (direct atom transfer radical polymerization) is initiated by active sites on the surface of the framework of the MC, and a hydrophilic restricted access layer is grafted. The restricted access type chiral chromatography MC has the advantages that the MC can be applied to direct injection analysis of biological samples, has high stability and is suitable for quick separation analysis of chiral drugs.

The invention relates to a polymer debonding agent for ceramic slurry with good grinding aid effect. The invention adopts an unsaturated monomer containing two carboxyl groups as an anionic monomer, which has better anchoring effect on ceramic clay ions and better degumming effect. Better and more efficient. The molecular structure of the debonding agent of the present invention contains a large number of diethanolamine groups with good grinding effect and good degumming, which can effectively shorten the ball milling time and improve the degumming performance; it is synthesized by water-based free radical polymerization, and is simple to operate and easy to realize. Industrial production.

The invention relates to a new process for producing a polyacrylamide high-efficiency papermaking fiber dispersant. Its technical scheme includes the following production process steps: pure water, sodium carbonate, sodium bicarbonate with a mass of 1%-10% of acrylamide, nonionic surfactant and anionic surfactant are sequentially added into a preparation kettle equipped with acrylamide. , the mass is 0.5%-20% functional monomer of acrylamide, and the mass is 1%-30% functional auxiliary agent of acrylamide, and the prepared liquid is injected into the polymerization kettle, and nitrogen gas is introduced to fully drive out oxygen. , adding an initiator to initiate polymerization; to obtain a gel-like product, the gel is formed into colloidal particles by a granulator, dried in a fluidized bed, and sent to a grinder after drying to be crushed, graded and packaged to obtain a paper-making fiber dispersant. The beneficial effects are as follows: the produced papermaking fiber dispersant has the advantages of good dispersion effect, high molecular weight, good water solubility, non-toxicity and high efficiency, low cost and the like.

The invention discloses a luminous functional composite material, which is a composite material of polystyrene and inorganic nano-oxides, characterized in that: the polystyrene is polystyrene with carboxylic acid functional groups at both ends, The material is selected from nanometer titanium dioxide, composite oxide of nanometer titanium dioxide, copper and chromium, nanometer zinc oxide or nanometer zinc-aluminum composite oxide. The preparation method is to synthesize polystyrene with benzoic acid unit at one end and chlorine atom at the other end by atom transfer radical polymerization; Polystyrene; final modification with inorganic nano-oxides. The polymer / nanoparticle composite material obtained by the present invention has red shift or blue shift relative to the fluorescence emission spectrum of the polymer, and becomes a new way to adjust the emission spectrum; at the same time, the composite material has good solubility and film-forming properties , has potential application value in light-emitting devices.

The invention discloses a preparation method of self-adhesive conductive hydrogel, which belongs to the technical field of biological material preparation. The invention comprises the following steps: firstly, introducing double bonds on biomacromolecules through methacrylic anhydride to obtain double bonded biomacromolecules. Then polydopamine functionalized conductive nanomaterials are prepared, and finally the self-adhesive conductive hydrogel is prepared by photoinitiating free radical polymerization of the double-bonded biomacromolecule and the polydopamine functionalized conductive nanomaterials. The invention learns from the adhesion of imitation mussel materials, introduces adhesive phenolic hydroxyl functional groups, and realizes the regulation and control of hydrogel self-adhesive performance by changing the content of the phenolic hydroxyl functional groups. In addition, the self-adhesive conductive hydrogel prepared by the present invention has good electrical conductivity, mechanical properties and biocompatibility, which broadens the application range of the hydrogel; the preparation method of the present invention is simple and easy, and the polymerization process is controllable , fast polymerization, low energy consumption and other advantages.

The invention relates to a method for synthesizing polyaspartic acid by using maleic anhydride and ammonia gas. The molten maleic anhydride and ammonia gas are subjected to a substitution reaction in a closed reactor. After the substitution reaction is completed, the remaining gas is absorbed; Sodium solution, carry out neutralization reaction to obtain a mixture of sodium maleamate and ammonium maleamate; directly heat up the product in a closed reactor, and carry out polycondensation reaction under stirring. After the polycondensation reaction is completed, evaporate the water to obtain polysuccinate imide solid; add water to another reaction kettle, start stirring, add polysuccinimide solid, slowly add sodium hydroxide solution, heat up for hydrolysis reaction, and obtain polyaspartic acid solution; the present invention simplifies production The weight average molecular weight of the obtained polyaspartic acid is 2000-15000, and the molecular weight distribution index is 1.5-1.65, which can meet the molecular weight requirements of different application fields, and the production process is environmentally friendly.

The invention relates to a multi-responsive polymer nanocarrier with a rapid cell penetrating characteristic. The nanocarrier is formed by self-assembling of a multi-responsive amphipathic triblock copolymer, the nanocarrier adopts an onion structure sequentially comprising an acid-responsive PLLA core, cyanine molecules with a near infrared absorption characteristic, a hydrogen-peroxide-responsive PPI (polyphenyl isocyanide) intermediate layer and a left-handed spiral hydrophilic PPI hydrophilic chain from inside to outside sequentially, wherein the structure of the multi-responsive amphipathic triblock copolymer is shown in the general formula in the specification, R1 is a group with stimulation responsiveness, and R2 is a chiral PEG hydrophilic chain; x ranges from 20 to 50, y ranges from 20 to 50, and z ranges from 30 to 80. The multi-responsive polymer nanocarrier can be used for transporting hydrophobic dye molecules and medicine molecules, can rapidly and efficiently penetrate cell membranes, has multiple stimuli-responsiveness, realizes programmable controlled release of medicines and has a chemical-photothermal collaborative treatment characteristic.

The invention discloses a function prepolymer and a preparation method and application thereof. The function prepolymer is a butyl acrylate polymer and prepared from a monomer, modified matter and an emulsifying agent through emulsion polymerization. A synthetic thickener, liquid disperse dye and the function prepolymer are mixed with water and evenly stirred to obtain printing paste; printing and drying of a polyester fabric are achieved through the obtained printing paste on a rotary screen printing machine or a mobile screen printing machine, then high-temperature processing is carried out on a tentering heat setting machine, and a printed polyester fabric is obtained. According to the technical scheme, the printing process is short, the hand feeling of the fabric is soft, postprocessing is not needed, a large amount of water and energy are saved, almost no wastewater is drained, processing equipment is conventional, and the printing processing technology is environmentally friendly.

The present invention relates to wide molecular weight distributed fluororubber and a preparation method thereof, wherein the glass-transition temperature of the fluororubber is between 20 DEG C and 60 DEG C below zero. The preparation method is characterized in that organic groups are led into chain terminal groups of fluororubber, wherein the weight-average molecular weight is between 10,000 and 9,000,000; Mw / Mn is between 2.50 and 20; the tensile strength is between 13.0 and 20.0 MPa; and the maximum elongation is between 150 and 300 percent. Water is adopted as a medium and organic peroxide is adopted as an initiator, and the chemical coagulation method is utilized for coagulation, washing and dehydration. The crude fluororubber obtained has wide molecular weight distribution, good processability and application performance, high production efficiency, low rejection rate and superior processability, and is difficult to generate rill marks in the process of vulcanization; the processability of subsequent products under the condition of certain strength is maximumly improved; and hermetical and continuous production is realized. The polymer can be formed by means of die stamping, extruding, injection and so on when being processed and applied.