512results about How to "Suitable for the needs of large-scale industrial production" patented technology

The invention provides a pneumococcal polysaccharide and protein conjugated vaccine and a preparation method thereof. The pneumococcus polysaccharide protein conjugated vaccine comprises one or more streptococcus pneumoniae capsular polysaccharide and protein coupled immune conjugates, and at least one of the immune conjugates is formed by coupling a single streptococcus pneumoniae capsular polysaccharide with two or more proteins. Compared with the existing pneumococcal conjugated vaccine, the pneumococcal polysaccharide and protein conjugated vaccine has stronger immunogenicity, and can cause immune response in a wider crowd; meanwhile, the two carrier proteins are covalently coupled through the polysaccharide, the protective protein antigen epitope induces higher immune response compared with the mixed injection of the two proteins, and through mutual synergy, the immunogenicity of the carrier protein is further improved and the immune response of the body to the polysaccharide is improved; the preparation method is simple, and meets the requirement of large-scale industrial production.

The invention provides formula powder for phenylketonuria children and a preparation method thereof. The formula powder comprises solid glucose syrup, amino acid, fatty acid, nucleotide, fish oil, dietary fiber, composite vitamins, composite mineral substances and an emulsifier, and is prepared by using a wet-method preparation process of materials. According to the formula powder, special free amino acid is adopted, a proper amount of free L-tyrosine is screened and optimized, and phenylalanine is removed, so that the physiological needs of sick children are met, and at the same time hypersensitivity of phenylketonuria infants is effectively prevented; in the formula, the components have the mutual synergistic effect, the powder is approximate to breast milk in absorption, taste and the like, children can absorb sufficient nutrition after taking the powder, and meanwhile anaphylaxis such as diarrhea can be effectively reduced; and the formula powder is simple in preparation method and applicable to requirements of large-scale industrial production.

This invention relates to a production technique of perilla-derived rosmarinic acid which is accessible for large-scale industrial production. Perilla leaves serving as raw materials are dipped in acidic water and the mixture undergoes filtration with the extracted liquid adsorbed and desorbed in macroporous adsorption resin; the desorbed liquid is vacuum distilled to obtain romarinic acid with a purity of 10%; the 10%-purity rosmarinic acid product is extracted with petroleum ether and the organic phase is vacuum distilled to obtain rosmarinic acid with a purity of 50%; the 50%-purity rosmarinic acid product is gradient eluted with ethanol solutions of different concentrations in adsorption resin and the 95% eluent is vacuum-condensed and crystallized to produce a rosmarinic acid product with a purity of 95%. This invention has the advantages of simple production technique, easy operation, low cost, variable product types, security and reliability and therefore it is applicable in producing food additives, medical intermediates and cosmetics.

The invention discloses traditional Chinese medicine granules for controlling red-skin diseases of grass carps and a preparation method of the traditional Chinese medicine granules. The traditional Chinese medicine granules are composed of radix gentianae, radix scutellariae, cortex phellodendri, rheum officinale, sophora flavescens, herba houttuyniae, kalmegh and radix glycyrrhizae. The traditional Chinese medicine granules comprise the following components, by weight, 2-4 parts of radix gentianae, 2-4 parts of radix scutellariae, 2-4 parts of cortex phellodendri, 1-2 parts of rheum officinale, 1-2 parts of sophora flavescens, 1-2 parts of herba houttuyniae, 1-2 parts of kalmegh and 1-2 parts of radix glycyrrhizae. The traditional Chinese medicine granules are prepared by conducting decoction and then adding cane sugar and starch. The traditional Chinese medicine materials are reasonably combined in the traditional Chinese medicine granules for controlling the red-skin diseases of the grass carps, therefore, the antisepsis and anti-inflammation efficacy and the efficacy of strengthening immunity are very remarkable, a drug for effectively treating the red-skin diseases of the grass carps is provided for fish culture, the traditional Chinese medicine granules have the advantages of being rapid in effectiveness, definite in curative effect and free of medicine residues and any toxic and side effect, and the preparation method is simple and capable of meeting the requirements for large-scale industrial production.

The invention provides a fishing Chinese medicinal composition with antibacterial and antibiotic functions and a preparation method thereof. The Chinese medicinal composition mainly comprises the following components in parts by weight: 8.1-18.1 parts of astragalus, 15-25 parts of large-head atractylodes rhizome, 8.5-18.5 parts of rhubarb, 1.5-11.5 parts of officinal magnolia bark, 28.5-38.5 parts of isatis root and 8.3-18.3 parts of liquoric root. In the fishing Chinese medicinal composition with the antibacterial and antibiotic functions, traditional Chinese medicines are combined reasonably, so that the Chinese medicinal composition has the effects of clearing heat, removing toxicity, resisting bacteria and diminishing inflammation, can be used for effectively improving the disease-resisting capabilities of fish and shrimp individuals, suppressing inflammations and greatly enhancing the immune functions of fishes and shrimps, is nontoxic and mild, has no residue in fish and shrimp bodies, does not cause medicament tolerance, and can be effectively degraded by organisms; and the preparation method is simple, has low cost, and is suitable for the requirement of large-scale industrial production.

The invention relates to a fish collagen peptide plant solid beverage as well as a preparation method and application thereof. Efficacy ingredients of the fish collagen peptide plant solid beverage consist of the following components in parts by weight of 50-300 parts of fish collagen peptide, 50-250 parts of a plant extract and 5-50 parts of a fruit and vegetable fermented product. Through adoption of the fish collagen peptide plant solid beverage disclosed by the invention, the problem that common collagen oral liquid cannot comprehensively protect skin, beautify the features and remove freckles is solved. As a healthy solid beverage capable of beautifying the features, the fish collagen peptide plant solid beverage has the advantages that small-molecule fish collagen peptide in the fishcollagen peptide plant solid beverage can be well absorbed and utilized by human bodies, and combination ingredients of the fish collagen peptide plant solid beverage contain various natural functioningredients, so that the skin health status of the human bodies can be improved and strengthened from various respects, skin ageing is avoided, and the fish collagen peptide plant solid beverage alsohas other health-care functions on the human bodies; and the preparation method is simple, and large-scale industrial production requirements are met.

The invention relates to a biofertilizer used for aquiculture pond and a preparation method thereof. The biofertilizer comprises the following components in parts by weigh: 100-200 parts of sodium humate, 100-200 parts of urea, 100-200 parts of calcium superphosphate, 100-200 parts of Bacillus subtilis and 200-600 parts of clinoptilolite powder; and the biofertilizer is prepared by mixing the above components. The biofertilizer can quickly act, adjust the water quality, and improve the substrate by reasonable formula; in addition to direct utilization by the aquatic organisms, the biofertilizer can combine with the hazardous materials in the water body substrate to detoxicate, and improve the metabolism of the algae at the same time, and increase the dissolved oxygen of the water body; and the preparation method is simple and is suitable for the requirement of large-scale industrial production.

The invention relates to a method for preparing organic montmorillonite by modifying with a fatty amine solution process. The method is characterized by comprising the following steps of: preparing montmorillonite suspending liquid; acidizing fatty amine; carrying out intercalation modifying on montmorillonite: selecting amine salt solution and montmorillonite suspending liquid after the fatty amine is acidized according to the proportion of fatty amine to montmorillonite being (0.1-0.6):1, and adding the amine salt solution after the fatty amine is acidized into the montmorillonite suspending liquid for intercalation reaction at the reaction temperature being 60-100 EDG C for 2-12 hours under stirring to enable the amine salt generated after the fatty amine is acidized to be intercalated between montmorillonite layers; and purifying the organic montmorillonite to obtain the organic montmorillonite. The method provided by the invention is low in raw material cost, good in intercalation effect, low in production cost and suitable for industrial production of enterprises; and the prepared organic montmorillonite can be widely applied to high polymer material such as rubber and plastic.

The invention provides nutritive formula powder suitable for increasing muscles of old people and a preparation method of the nutritive formula powder. The nutritive formula powder comprises the efficacy components of nonfat dry milk powder, protein powder, calcium beta-hydroxy-beta-methyl-butyrate, sunflower oil powder, glucose syrup powder, fine white granulated sugar / cane sugar, fructo-oligosaccharide, galactooligosaccharide, a grape seed extract, a cucumber seed extract, a vitamin premix, a trace element premix, and a mineral premix. The nutritive formula powder is obtained in a mixing manner, particularly the calcium beta-hydroxy-beta-methyl-butyrate is added, and the components are in synergism, so that nutrient requirements of the old people can be met, concentration of amino acidsnecessary for blood is increased, the synthesis of muscle protein is stimulated, the net synthesis level of the protein of the old people is increased, the nutrient requirements of crowds with sarcopenia are met, and the nutritive formula powder can treat or prevent sarcopenia.