The invention relates to a copper-zirconium-based amorphous alloy, which is mainly composed of copper and zirconium, and whose composition is expressed by the following formula: (Cu1-xZrx)aAlbMc, wherein, 0.40≤x≤ 0.60, 80≤a≤100, 0≤b≤14, 0≤c≤20, and a+b+c=100; metal element M is Y, La, Ce, Pr, Nd, Gd, Tb, Dy, Ho , Er, Ti, Ag, Ga, Hf, Ta, Nb, Ni, Co, or Fe. The preparation of the alloy is to mix the above-mentioned components Cu, Zr, Al and M according to the required atomic ratio in an electric arc furnace with an argon atmosphere adsorbed by titanium, and then melt and cool to obtain a master alloy ingot; then use conventional The metal mold casting method is to remelt the master alloy ingot in the air and cast it in a water-cooled metal mold to obtain the alloy. The alloy has high glass-forming ability, strong ability to inhibit crystallization, and can be made into larger sizes at very low cooling rates.