The invention relates to application of chickpea sprout extracts in medicines for preventing deficiency of
estrogen. The chickpea sprout extracts are chickpea sprout isoflavone extracts, are used as
estrogen receptor regulator, and are used for preparing medicines and health care products which are used for preventing or treating
climacteric syndrome and
osteoporosis. Tests show that the chickpea sprout isoflavone extracts can directly act onto the
uterus of a patient, can remarkably increase estradiol level in
blood serum, have regulating and controlling effects to a
hypothalamus-hypophysis- neuroendocrine
system, remarkably increase thighbone density and relative
bone volume of an SD (
Sprague Dawley) rat without the
ovary, increase the thickness of bone trabecula, reduce separating degree of the bone trabecula, decrease the quantity of
osteoclast, can alleviate bone loss of the thighbone of the rat due to the fact that the
ovary of the rat is removed, increase
bearing capacity of the thighbone, play an important role in regulating internal
secretion conditions of middle-aged and elderly women after
menopause, improving
menopause symptoms such as
hot flash, palpitate,
skin dryness and the like and reducing possibility of
osteoporosis, and lay a foundation in industrial development of functional factors of chickpeas.