30results about How to "Inhibition of self-aggregation" patented technology

The present invention relates to a molybdenum sulfide / graphene-graphene nano-belts aerogel composite material preparation method, which comprises: dispersing oxidized graphene in deionized water, and carrying out an ultrasonic treatment to obtain an oxidized graphene dispersing liquid; adding an oxidized graphene nano-belt dispersing liquid into the oxidized graphene dispersing liquid in a dropwise manner, stirring to obtain a mixed liquid, freezing with liquid nitrogen to obtain a solid, and carrying out freeze-drying to obtain the precursor of a graphene-graphene nano-belt gel; adding ammonium thiomolybdate to a solvent, and carrying out an ultrasonic treatment to obtain an ammonium thiomolybdate solution; and adding the precursor of the graphene-graphene nano-belt gel to the solution, standing, and carrying out a solvothermal reaction to obtain the molybdenum sulfide / graphene-graphene nano-belts aerogel composite material. According to the present invention, the method has characteristics of simple operation, easy control, low cost, no pollution, and easy large-scale production; and the prepared porous carbon nanometer aerogel has advantages of large specific surface area, stable chemical property, good conductivity, adjustable pore size, and the like.

The invention discloses positively charged water-soluble arm type dendritic ligand silicon phthalocyanine complexes as well as preparation methods and an application thereof. The complexes comprise di-(3,5-di(1',3'-methylpyridine propoxy)butanyloxy) axially substituted silicon phthalocyanine and di-(3,5-di(1',4'-isoquinoline butanyloxy)butanyloxy) axially substituted silicon phthalocyanine, wherein di-(3,5-di(1',3'-methylpyridine propoxy)butanyloxy) axially substituted silicon phthalocyanine is prepared from 3,5-di(1',3'-methylpyridine propoxy) phenyl methanol and silicon(IV) phthalocyanine dichloride or from 3,5-di-bromopropoxy) phenyl methanol and excessive methylpyridine and silicon(IV) phthalocyanine dichloride; di-(3,5-di(1',4'-isoquinoline butanyloxy)butanyloxy) axially substituted silicon phthalocyanine is prepared from 3,5-di(1',4'-quinoline butoxy) phenyl methanol and silicon(IV) phthalocyanine dichloride, or from 3,5-di(bromobutoxy) phenyl methanol and excessive isoquinoline and silicon(IV) phthalocyanine dichloride. The application of the complexes as a photosensitizer in photodynamic therapy is disclosed, especially the application to photoinactivation of MDRAB (multidrug-resistant acinetobacter baumannii).

The invention discloses a preparation method of molten-drop-resisting polyamide fiber or fabric. Under a normal temperature air condition, the fiber or fabric is radiated by virtue of electronic beams, then the fiber or fabric is placed into a monomer aqueous solution containing carboxyl groups to be under pre-reaction, and the fiber or fabric is enabled to be self-cross linked; then the fiber or fabric is padded in a polymerization inhibitor and a compound aqueous solution consisting of two monomers containing reactive double bonds, and the electronic beam radiation grafting is carried out after twice impregnation and twice rolling; after the grafting reaction is completed, the fiber or fabric can be boiled by virtue of treatment liquid so as to remove a grafted homopolymer to obtain the molten-drop-resisting polyamide fiber or fabric. The preparation method is simple and easy to operate and capable of implementing the industrialized production, and during a burning process of the prepared molten-drop-resisting polyamide fiber or fabric, a carbonized supporting layer can be rapidly formed on the surface of the fiber or fabric, so that the formation of molten drops is effectively inhibited, and the secondary harm caused by a high-temperature flame dropping object is avoided, and the situation threatening the human life can be prevented.

The invention relates to a serum albumin with a metal chelating function as well as a preparation method and an application in inhibition for the aggregation of beta-amyloid proteins. The serum albumin with the metal chelating function is obtained through modifying 1,4-butanediol diglycidyl ether on an amino group on the surface of a serum albumin at first, and then modifying a metal chelating agent iminodiacetic acid on an epoxy group of 1,4-butanediol diglycidyl ether, and the average modification number of iminodiacetic acid on each serum albumin ranges from 2 to 40. According to the serum albumin with the metal chelating function, which is disclosed by the invention, the chelating capacity of the serum albumin for metal ions is improved, and then the self-aggregation of the beta-amyloid proteins and an aggregation process of the beta-amyloid proteins under the induction of the metal ions are inhibited, and the cytotoxicity of beta-amyloid protein aggregates is reduced. The serum albumin with the metal chelating function is used for a medicine for treating the diseases related to beta-amyloid protein aggregation. The medicine is used for treating and slowing down Alzheimer disease and other diseases.

The invention discloses environment-friendly and flame-retardant water-soluble high-imino melamine resin and a production method thereof. The production method comprises steps as follows: low methylolmelamine is produced continuously by use of high-concentration formaldehyde; low methylol melamine is subjected to methoxylation, the pH value is controlled through acetic acid and ammonium acetate;acetylacetone is added to eliminate surplus formaldehyde; dealcoholization and dehydration treatment is performed, and the high-imino melamine resin is obtained. The high-imino melamine resin producedwith the method has excellent formaldehyde content, anti-static property or auto-agglutination property and is very suitable for being used as a coating, an insulating packaging material and the like, and zero discharge of wastewater can be realized in the whole production process.

The invention provides butylated amino resin produced by utilizing low-hydroxymethyl melamine. The amino resin is prepared by the following steps: continuously producing the low-hydroxymethyl melamineby utilizing high-concentration formaldehyde; butylating the low-hydroxymethyl melamine and controlling the pH (Potential of Hydrogen) value through acetic acid and ammonium acetate; adding acetylacetone to eliminate surplus formaldehyde; carrying out dealcholization and dehydration treatment. The amino resin produced by the invention has very excellent performance in the aspects of formaldehydecontent, antistatic performance or self-polymerization performance and the like, and has moderate polarity, high yield, moderate cost, good paint film leveling performance, high fullness and good flexibility and is suitable for OEM paint; in a whole production process, zero emission of wastewater can be realized.

The invention discloses silicon phthalocyanine substituted by a trianilino fluoro aryl benzyl ether dendritic ligand and a preparing method and application thereof. Firstly, 4'-(diphenylamino)-[1,1'-biphenyl]-4-carboxylic acid is synthesized from 4-bromotriphenylamine and phenylboronic acid, and is then subjected to condensation with hexafluorobisphenol A or bisphenol A respectively to prepare 4-(diphenylamino)-1-biphenylcarboxylic acid-1-carbobenzoxy-1,1,1,3,3,3-hexafluoropropyl phenol and 4-(diphenylamino)-1-biphenylcarboxylic acid-1-carbobenzoxy propyl phenol; and finally, the 4-(diphenylamino)-1-biphenylcarboxylic acid-1-carbobenzoxy-1,1,1,3,3,3-hexafluoropropyl phenol and the 4-(diphenylamino)-1-biphenylcarboxylic acid-1-carbobenzoxy propyl phenol react separately with silicon phthalocyanine dichloride to synthesize bis-(4-(diphenylamino)-1-biphenylcarboxylic acid-1-carbobenzoxy-4-(1,1,1,3,3,3-hexafluoropropyl-4-phenoxy) axially substituted silicon phthalocyanine and bis-(4-(diphenylamino)-1-biphenylcarboxylic acid-1-carbobenzoxypropylphenoxy) axially substituted silicon phthalocyanine. The products can be used as fluorescence imaging agents and photodynamic therapy photosensitizers.

The invention provides application of an alpha-pyrone derivative namely 6-(3-hydroxypentyl-1-alkenyl)-2H-pyran-2-ketone to treatment of psoriasis and a pharmaceutical composition comprising the same compound and further provides a chemical preparation method of 6-(3-hydroxypentyl-1-alkenyl)-2H-pyran-2-ketone. The preparation method is simple in operation, high in product yield and low in cost, large-scale production can be realized, and problems of step complexity, low product yield and difficulty in mass preparation in application of an existing biological preparation method are solved.

The invention discloses a preparation method of a special material for a polyethylene regenerated manufacturing plastic pipe by chain extending and mixing through a one-step method, which solves the problems of high regeneration cost, complicated technology and poor property in the existing polyethylene regenerated manufacturing plastic pipe. The preparation method adopts the technical scheme that oil pot recycling resin, barrel recycling resin, thin film recycling resin, slat floating polyethylene recycling resin, a comonomer, an active dispersant, an initiator, glycidyl methacrylate, a regulator and an antioxidant are used as raw materials, and are subjected to chain extension and modification through the one-step method. The preparation method has the advantages that the technology is simple, the cost is low, the property requirement is met, and the recycling of low-quality recycling material is promoted.

The invention discloses a fluoro aryl benzyl ether dendritic (phthalocyanino) silicon complex as well as a preparation method and applications thereof. The preparation method comprises the following steps: firstly, synthetizing dichloro (phthalocyanino) silicon; then, in the presence of potassium carbonate, reacting p(nitro or cyano, ester, benzophenone) benzyl bromide with 2,2-bi(4-hydroxyphenyl) hexafluoropropane so as to synthetize 2-(4-hydroxyphenyl)-2'-(4-(4-nitro or cyano or ester or benzophenone-benzyloxy); finally, respectively carrying out reflux reaction on dichloro(phthalocyanino) silicon and 2-(4-hydroxyphenyl)-2'-(4-(4-nitro or cyano or ester or benzophenone-benzyloxy) hexafluoropropane in methylbenzene so as to synthetize di-(2-(4-phenoxy)-2'-(4-(4-nitro or cyano or ester or benzophenone-benzyloxy)hexafluoropropane) for axially replacing a silicon (IV) phthalocyanine complex. In such a way, a fluoro dendritic ligand modified phthalocyanine complex becomes a photosensitizer with good photodynamic therapy potential.

The invention discloses a method for preparing pseudoionone. The method uses phosphate as a catalyst to prepare pseudo-ionone by a liquid-liquid two-phase method, can inhibit the self-polymerization of citral, improve catalytic selectivity, has high catalyst activity, can be recycled, and is environmentally friendly.

The invention provides a preparation method of sulfur-doped molybdenum selenide / graphene-graphene nanoribbon aerogel. The method is characterized by comprising the following steps of (1) carrying out freeze drying and burning on a mixed dispersion liquid of a graphene oxide and a graphene oxide nanoribbon to obtain graphene-graphene nanoribbon hybrid aerogel; (2) dispersing selenium powder into hydrazine hydrate, mixing the obtained selenium powder dispersion liquid with a sodium molybdate water solution to obtain a mixed liquid, immersing the graphene-graphene nanoribbon hybrid aerogel obtained in the step 1 into the mixed liquid, adding an N,N-dimethyl formamide solvent and obtaining a molybdenum selenide / graphene-graphene nanoribbon aerogel composite material through solvothermal reaction; and (3) burning the molybdenum selenide / graphene-graphene nanoribbon aerogel composite material obtained in the step (2) and powdered sulfur to obtain the sulfur-doped molybdenum selenide / graphene-graphene nanoribbon aerogel. The prepared sulfur-doped molybdenum selenide / graphene-graphene nanoribbon aerogel composite material has the advantages of being stable in structure, large in specific surface area, good in electrical conductivity, adjustable in aperture and the like.

A method for preparing an iron-nickel battery negative electrode material, belonging to the technical field of battery negative electrode material production, performing a gas-solid reaction with a suspension obtained by mixing carbon nanotubes, graphene, nanometer iron tetroxide, calcium hydroxide and water , when the pH value of the suspension drops to 7, the filter cake is obtained by filtration, and then the filter cake is mixed with an aqueous solution of hydroxyethyl cellulose to obtain a composite nanomaterial slurry, which is coated on a copper grid and dried in vacuum and then rolled and slicing to prepare the negative plate of the iron-nickel battery. In the present invention, through the gas-solid reaction of carbon dioxide and calcium hydroxide, the submicron calcium carbonate supports graphene, carbon nanotubes, and ferric oxide nanocomposites, thereby preparing a high gram capacity, low resistance and good cycle stability. Iron-nickel battery anode material.