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35results about How to "Efficient split" patented technology

Parametric modeling design method for fabricated building

The invention provides a parametric modeling design method for a fabricated building, which comprises the following steps of: extracting parameters: splitting each component from a CAD structure construction drawing of the building, representing each different component with different parameters, and extracting parameter information of each component; inputting parameters: storing the parameter information of each component into a database, and inputting the parameter information into UG software to form a three-dimensional model of each component; assembling collision: correspondingly assembling three-dimensional models of a plurality of adjacent components in UG software, and carrying out collision detection and collision adjustment on the components; wherein the three-dimensional modelof the qualified standard component is converted into a two-dimensional drawing; a plurality of standard components are used for jointly forming the fabricated building. By using the method disclosedby the invention, the structure construction drawing of the house can be efficiently split into a plurality of standard components, the two-dimensional drawing of each standard component can be accurately given out in detail, and the material list for production and manufacturing can be accurately calculated as soon as possible.
Owner:中民筑友房屋科技集团有限公司

Device for combination of light of different wavelengths

The present invention relates to a method for combining or for splitting the beam paths of substantially nonpolarized light of at least three different wavelength intervals. The splitting or the combining of the beam path of light of those wavelength intervals located between the other wavelength intervals takes place when the beam paths of the light of the two other wavelength intervals are already or still combined. The present invention also relates to an illumination unit comprising a white light source and utilizing this method by means of interference filters for splitting the white light into red, blue and green light beams. The invention also relates to an illumination unit comprising a red, green and blue light source and utilizing these methods by means of interference filters for the combination of the beam paths of the light sources.
Owner:OERLIKON SURFACE SOLUTIONS AG PFAFFIKON

Water Purifying Apparatus

Provided is a water purifying apparatus capable of efficiently producing purified water from raw water. The water purifying apparatus comprises: a casing (11) having a circulation path; a splitter device (15) disposed within the casing (11) and adapted to split raw water into droplets and create a carrier airflow (A1) capable of circulating along the circulation path and carrying water vapor evaporated from the droplets (D1); and a condenser (19) disposed within the casing (11) at a position downstream of the splitter device (15) in a direction of the carrier airflow and adapted to condense the water vapor to create purified water. The splitter device (15) comprises a rotary shaft (15a) extending in an up-down direction of the casing (11), and a blade (152A to 152Q) radially attached to the rotary shaft (15a) and having irregularities (152p, 152q, 152r, 152s, 152t).
Owner:CIP SOFTWARE

Triazole singly-bonded fully-substituted cyclodextrin silica gel chiral fixed phase and preparation method thereof

The invention discloses a click reaction based preparation method and use of a triazole singly-bonded fully-substituted cyclodextrin silica gel chiral fixed phase. In the method, the triazole singly-bonded fully-substituted cyclodextrin silica gel chiral fixed phase with high chemical stability is prepared by the selective azidation of the position 6 of cyclodextrin and full substitution and alkynylation of silica gel, by using a newly developed catalyst and by a click reaction, and the structural design of cyclodextrin is enriched. The triazole singly-bonded fully-substituted cyclodextrin silica gel chiral fixed phase demonstrates high chiral resolution capacity for amino acid and acidic and neutral racemate medicines and is expected to be used in field of medicine chiral resolution of various chromatographic techniques as a chiral fixed phase.
Owner:NANJING XINLUOMEI NEW MATERIALS

Chiral triptycene polyimide film, preparation method thereof and application of chiral trisphene polyimide film in chiral molecular separation

The invention belongs to the technical field of polymer film separation, and discloses preparation and application of two chiral triptycene polyimide films. The preparation comprises the steps of (1)carrying out polymerization reaction on a dianhydride monomer compound and optical pure 2,6-diaminotriptycene to obtain two chiral triptycene polyimide; (2) preparing a chiral film by a solvent evaporation method; and (3) separating racemation micromolecules by the chiral film through a racemation film experiment. The preparation has the advantages of low material cost, simple film making method,outstanding chiral separation effect and the like, and has large application prospect in the aspect of chiral resolution and the like.
Owner:HUAZHONG UNIV OF SCI & TECH

2-nitro-benzoyl-imino-acenaphthylene derivative compound and use thereof

The invention relates to a dinitrobenzene formacyl imdo group acenaphthene derivatization compound that has the structure of general expression (I). And R1 represents hydrogen, C1-C3 is alkyl, R2 is alkylidene group, alkenyl, and R3 expresses one-hydrogen or two-hydrogen. After taking acylation reaction of arene, alpha-H replacing reaction of ketone, and reduction amination of ketone carbonyl, and acylation reaction of amine acyl halide, the product would be gained. The invention also relates to the single antipode of the compound, including chiral reagent or chiral additive. It could be used as chiral reagent in film method and chiral stationary phase or chiral mobile phase.
Owner:SICHUAN UNIV

Application of chiral aminophenol ligand to asymmetric synthesis of efavirenz

The invention relates to an application of a chiral aminophenol ligand to asymmetric synthesis of efavirenz. A chiral aminophenol ligand compound is used for inducing asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-1,3-benzoxazine-2-ketone (Efavirenz). The ligand is cheap, easily available, safe and recoverable, is used in asymmetric synthesis of efavirenz, and has the advantages of high yield, good enantioselectivity, simplicity and convenience in operation, capability of realizing industrialized production and good product quality.
Owner:SHANGHAI INST OF ORGANIC CHEMISTRY - CHINESE ACAD OF SCI

Catalyst for splitting racemic epoxyalkane and application thereof

The invention relates to a catalyst for splitting racemic epoxyalkane. The catalyst is composed of nitrogen-containing organic alkali or quaternary ammonium salt, and Cr (Salen) [(R,R) / (S,S)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino chromium (III) chloride], the mole ratio of the organic alkali or quaternary ammonium salt to the Cr (Salen) is 0.1-10; in the process of carrying out asymmetric ring-opening splitting of the racemic epoxyalkane, the splitting conversion rate of the catalyst to epoxyalkane can be greater than 49%, and the ee value of a split product 1-azido-2-trialkyl siloxane can be over 90%. The catalyst mainly solves the problem that previous catalytic racemic epoxyalkane is low in asymmetric ring-opening reaction activity, large in application amount of the catalyst and low in enantioselectivity, realizes the efficient splitting of racemic epoxyalkane, and can obtain high-purity chiral epoxyalkane and trialkyl siloxane.
Owner:DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI

Method for separating ofloxacin enantiomer

The invention discloses a method for separating an ofloxacin enantiomer. The method for separating the ofloxacin enantiomer comprises the steps: (1) dissolving an ofloxacin sample to obtain an ofloxacin solution; and (2) separating the ofloxacin enantiomer in the ofloxacin solution by using a simulated moving bed chromatography system, wherein chromatographic conditions are that the chromatographic column is a Chiralcel OD-H chiral column; the fixed phase is silica gel, the surface of which is coated with cellulose-tri[3, 5-xylyl carbamate]; and the mobile phase is a mixed solution containing ethanol, n-hexane and phosphoric acid. The method for separating the ofloxacin enantiomer has the advantages of simple process and stable and reliable product and can be used for industrial mass production.
Owner:WATERSTONE PHARMA WUHAN

Preparation method of (S)-5-bromo-1, 2, 3, 4-tetrahydro-N-Boc-isoquinoline-1-carboxylic acid

ActiveCN112724084AThe synthetic route is reasonable and effectiveRaw materials are easy to getOrganic chemistry methodsQuinolineFormic acid
The invention discloses a preparation method for synthesizing (S)-5-bromo-1, 2, 3, 4-tetrahydro-N-Boc-isoquinoline-1-carboxylic acid, and belongs to the technical field of medical intermediates. The method comprises the following steps: reacting o-bromophenylethylamine serving as a raw material with benzyl chloroformate in an alkaline environment to obtain benzyl o-bromophenylethylamine formate; then carrying out cyclization reaction with glyoxylic acid under the catalysis of acid; then carrying out palladium-carbon catalytic hydrogenation to remove protection, so as to obtain 5-bromo-1, 2, 3, 4-tetrahydroisoquinoline-1-carboxylic acid; finally, obtaining the (S)-5-bromo-1, 2, 3, 4-tetrahydro-N-Boc-isoquinoline-1-carboxylic acid through induced resolution and Boc protection. The method is simple, convenient and stable in process operation, high in yield, environmentally friendly, cheap and easily available in raw materials and beneficial to industrial production.
Owner:CHEMVON BIOTECH CO LTD

Double-substituted 6-alkyl imidazolium-6-ammonium-beta-cyclodextrin with double positive electricity centers and preparation method thereof

The invention discloses double-substituted 6-alkyl imidazolium-6-ammonium-beta-cyclodextrin with double positive electricity centers and a preparation method thereof. The structural formula of double-substituted 6-imidazolidinylnio-6-ammonium-beta-cyclodextrin is as shown in the specification. The preparation method comprises the following steps: adding imidazole in 4-methyl-benzene sulfonyl chloride and then reacting with beta-cyclodextrin so as to obtain 6-p-methyl-benzene-sulfonyl-beta-cyclodextrin (Ts-CD) the 6-hydroxyl of which is substituted; reacting Ts-CD with sodium azide so as to obtain 6-azido-beta-cyclodextrin, namely, N3-CD; reacting N3-CD with 2,4,6-trimethyl benzene sulfonyl chloride so as to obtain 6-azido-6-(2,4,6-trimethyl benzene sulfonyl)-beta-cyclodextrin, namely, N3-Mess-CD; reacting N3-Mess-CD with alkyl imidazole so as to obtain double-substituted 6-azido-6-alkyl imidazolium-beta-cyclodextrin, and reducing azido to amino with triphenylphosphine so as to obtain double-substituted 6-amino-6-alkyl imidazolium-beta-cyclodextrin; and carrying out amino hydrochlorination and ion exchange so as to obtain double-substituted 6-alkyl imidazolium-6-ammonium-beta-cyclodextrin with the double positive electricity centers. The obtained cyclodextrin has good water solubility and effective chiral resolution capacity.
Owner:NANJING UNIV OF SCI & TECH

Flag mushroom cup nozzle assembly and method

An alignable conformal, cup-shaped flag-mushroom fluidic nozzle assembly is engineered to generate a flat fan or sheet oscillating spray of viscous fluid product 316. The nozzle assembly includes a cylindrical flag mushroom fluidic cup member 180 having a substantially closed distal end wall with a centrally located snout defined therein. The flag mushroom cup assembly effectively splits the operating features of the fluidic circuit between a lower or proximal portion formed in the housing's sealing post member and an upper, or distal portion formed in cup member 180 which, in cooperation with the sealing post's distal surface, defines an interaction chamber 192 fed by impinging jets each comprising a continuous distribution of streamlines that impinge at selected angles to define arcs providing a lesser degree of impingement at a centered axial plane within the exit orifice 194 and a greater degree of impingement at the edges of exit orifice 194.
Owner:DLHBOWLES INC

Malate dehydrogenase mutant gene and construction method and application thereof

The invention discloses a malate dehydrogenase mutant gene and a construction method and application thereof, and belongs to the technical field of biological genetic engineering. The malate dehydrogenase mutant gene is characterized in that streptomyces coelicolor malate dehydrogenase is taken as a template, a gene sequence capable of expressing the malate dehydrogenase is constructed through genetic engineering measures such as primer design, stepwise PCR (polymerase chain reaction), fusion PCR, transformed bacteria resistance screening and nucleotide sequencing, and the constructed malate dehydrogenase is transferred into DE3 strains of escherichia coli to be expressed; the activity of the expressed malate dehydrogenase is two times or above that of malate dehydrogenase under wild-typesample expression, and more efficient resolution and purification enzymes are provided for production of D-malic acid.
Owner:ANHUI NORMAL UNIV

Polymer fiber spinning component disassembly system and disassembly method

The invention belongs to the technical field of melt spinning. A dismantling system for polymer fiber spinning components, which is used to realize the dismantling of spinning components, specifically including a heat preservation trolley, a press, a force wrench, an ejector, a holder, an inner core decomposition device and a separation knife, The heat preservation trolley is used for storage and heat preservation of the spinning assembly; the press is used to apply pressure to the deflector of the spinning assembly, and the pressure head of the press fits the deflector accordingly; the force wrench includes the working end and the force application arm, the working end is matched with the lock nut; the ejector device is used to separate the inner core of the assembly in the spinning assembly from the ejection housing; the clamper is used for clamping and transferring of the spinning assembly; the inner core disassembly device is used for The aluminum ring on the sand box is extruded and deformed; the separating knife is used for component separation and cleaning of residual materials. Also disclosed is a method for dismantling polymer fiber spinning components. The structural design is reasonable, which can greatly improve the disassembly efficiency, and burn the disassembled parts, which improves the cleaning efficiency, reduces the difficulty of operation, and makes each process proceed in an orderly manner.
Owner:SHEN MA INDUSTRY CO LTD

Double-substituted 6-alkyl imidazolium-6-ammonium-beta-cyclodextrin with double positive electricity centers and preparation method thereof

The invention discloses double-substituted 6-alkyl imidazolium-6-ammonium-beta-cyclodextrin with double positive electricity centers and a preparation method thereof. The structural formula of double-substituted 6-imidazolidinylnio-6-ammonium-beta-cyclodextrin is as shown in the specification. The preparation method comprises the following steps: adding imidazole in 4-methyl-benzene sulfonyl chloride and then reacting with beta-cyclodextrin so as to obtain 6-p-methyl-benzene-sulfonyl-beta-cyclodextrin (Ts-CD) the 6-hydroxyl of which is substituted; reacting Ts-CD with sodium azide so as to obtain 6-azido-beta-cyclodextrin, namely, N3-CD; reacting N3-CD with 2,4,6-trimethyl benzene sulfonyl chloride so as to obtain 6-azido-6-(2,4,6-trimethyl benzene sulfonyl)-beta-cyclodextrin, namely, N3-Mess-CD; reacting N3-Mess-CD with alkyl imidazole so as to obtain double-substituted 6-azido-6-alkyl imidazolium-beta-cyclodextrin, and reducing azido to amino with triphenylphosphine so as to obtain double-substituted 6-amino-6-alkyl imidazolium-beta-cyclodextrin; and carrying out amino hydrochlorination and ion exchange so as to obtain double-substituted 6-alkyl imidazolium-6-ammonium-beta-cyclodextrin with the double positive electricity centers. The obtained cyclodextrin has good water solubility and effective chiral resolution capacity.
Owner:NANJING UNIV OF SCI & TECH

Resolution method for racemate of trandolapril intermediate

InactiveCN110452950ASplit method securityThe splitting method is environmentally friendlyFermentationPichia pastorisRoom temperature
The invention discloses a resolution method for a racemate of a trandolapril intermediate. The trandolapril intermediate is shown by a structural formula I and subjected to a catalytic reaction undera weak alkaline environment by utilizing pichia pastoris lipase. It is found through research that the pichia pastoris lipase can resolve the racemate of the trandolapril intermediate under a room-temperature condition and an alkaline condition to obtain the intermediate suitable for producing trandolapril, and the resolution method is safe, environmentally friendly and free of toxins and pollution.
Owner:JIANGSU YONGDA PHARMA

Accurate matching and efficient splitting experimental device for early strength of activated fly ash-doped cement test piece

InactiveCN112881136AEarly Strength Precise Proportion PreciseLow early strengthPreparing sample for investigationMicro nanoPipe
The invention discloses an accurate matching and efficient splitting experimental device for early strength of an activated fly ash-doped cement test piece. The matching precision of the fly ash and the micro-nano material is an important factor influencing the early strength of a micro-nano material activated fly ash-doped cement test piece, and weighing for manufacturing a standard test piece is carried out manually and gradually; due to multiple sensitive factors of the early strength, the standard test piece is mostly taken out from a matching cylindrical pipe and is disassembled from the bottom or the top end by means of external force, and the test result is influenced, so that the accurate matching and efficient splitting experimental device for early strength of the test piece is needed. Different components such as micro-nano materials, coal ash and water are distributed to the middle-layer vibration platform through 4-6 sets of precise metering filling pipes arranged on the upper-layer platform, are uniformly stirred through a stirring system and then are lowered to the lower-layer early strength matching cylindrical pipe on the basis of full vibration of the vibration platform; by means of layered stirring and compaction of an intelligent stirring system and full vibration of a lower-layer vibration platform, after 6-8 hours, the early strength matching cylindrical pipe is placed in a strength testing device to be laterally split, and then accurate early strength matching and efficient splitting can be completed.
Owner:ANHUI UNIV OF SCI & TECH

Low-code delivery method based on software development

The invention relates to a low-code delivery method based on software development, which comprises the following steps: obtaining functional modules of software to be delivered, each functional module comprising at least two functional units, the two functional units being used for aggregating into one functional module, functional units contained in the functional modules are polymerized from other functional modules on the basis of original functions; the storage module is provided with a first storage unit and a second storage unit, the first storage unit is used for storing a first-layer logic relation, and the second storage unit is used for storing a second-layer logic relation; detecting the storage data volume in the first storage unit and the second storage unit; and adjusting the aggregation condition of the functional unit or the functional module during delivery according to the data volume stored in the first storage unit and the second storage unit. According to the method, the functional units and functional module division of the to-be-delivered software are reasonably adjusted, so that the delivery code quantity is greatly reduced during delivery, the delivery efficiency is improved, and the delivery time limit and the delivery period are shortened.
Owner:北京大唐神州科技有限公司

Chiral triptycene polyimide film and its preparation method and application of chiral molecular separation

The invention belongs to the technical field of polymer film separation, and discloses preparation and application of two chiral triptycene polyimide films. The preparation comprises the steps of (1)carrying out polymerization reaction on a dianhydride monomer compound and optical pure 2,6-diaminotriptycene to obtain two chiral triptycene polyimide; (2) preparing a chiral film by a solvent evaporation method; and (3) separating racemation micromolecules by the chiral film through a racemation film experiment. The preparation has the advantages of low material cost, simple film making method,outstanding chiral separation effect and the like, and has large application prospect in the aspect of chiral resolution and the like.
Owner:HUAZHONG UNIV OF SCI & TECH

Method for separating ofloxacin enantiomers

The invention discloses a method for separating an ofloxacin enantiomer. The method for separating the ofloxacin enantiomer comprises the steps: (1) dissolving an ofloxacin sample to obtain an ofloxacin solution; and (2) separating the ofloxacin enantiomer in the ofloxacin solution by using a simulated moving bed chromatography system, wherein chromatographic conditions are that the chromatographic column is a Chiralcel OD-H chiral column; the fixed phase is silica gel, the surface of which is coated with cellulose-tri[3, 5-xylyl carbamate]; and the mobile phase is a mixed solution containing ethanol, n-hexane and phosphoric acid. The method for separating the ofloxacin enantiomer has the advantages of simple process and stable and reliable product and can be used for industrial mass production.
Owner:WATERSTONE PHARMA WUHAN

Shaft pulling device used for pulling airplane anti-icing valve guide shaft and shaft pulling method

The invention discloses a shaft pulling device used for pulling an airplane anti-icing valve guide shaft. The shaft pulling device comprises a taper pipe barrel (3), a lock nozzle (1), a lock nozzle square-head nut (6), a positioning base (2), two long wrench handles (5), two short wrench handles (5), two L-shaped fastening and positioning blocks (7) and a rotating nut (4). The two L-shaped fastening and positioning blocks (7) are oppositely and symmetrically fixed to the two ends of a waist plate of the positioning base (2) through bases via connecting pieces; the lock nozzle (1) penetrates in the taper pipe barrel (3); the lock nozzle square-head nut (6) is screwed on an outer thread at one end of the lock nozzle (1); and the above parts penetrate a middle large through hole of the waist plate of the positioning base (2) together after being assembled. The positioning base (2) is fixed to a valve shell provided with the airplane anti-icing valve guide shaft.
Owner:GUANGZHOU AIRCRAFT MAINTENANCE ENG
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