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43results about How to "Effective split" patented technology

Method and device for splitting homologous chromosomes of polyploid genome and application thereof

The invention provides a method and a device for splitting homologous chromosomes of a polyploid genome and application thereof. The splitting method comprises the following steps: calculating the interaction strength between genome contigs and the interaction strength in the contigs according to a comparison file obtained by comparing HiC data with a polyploid genome sequence; breaking the overlapping groups with connection errors according to the interaction strength in each overlapping group; performing mutual comparison by utilizing the interrupted overlapping groups to obtain the similarity among the overlapping groups; and clustering all the contigs according to the interaction strength among the contigs and the similarity among the contigs to realize the splitting of the homologouschromosomes of the polyploid genome. The method is used for identifying an overlapping group which is wrongly connected by using interaction strength in the overlapping group, breaking at a wrong place, clustering is carried out by identifying the similarity between the overlapping groups and utilizing the interaction strength and the similarity between the overlapping groups, so that the homologous chromosomes can be effectively split.
Owner:天津诺禾致源生物信息科技有限公司

Official account management method and device, computer equipment and storage medium

The embodiment of the invention discloses an official account management method and device, computer equipment and a storage medium. The method includes the following steps: dividing an official account management platform system into a plurality of micro-service modules according to preset rules; if user login information of a user is received, determining whether the user login information matches the preset user login information; if yes, receiving an interface access request of the user; analyzing the interface access request to obtain corresponding user mark information and access requestinformation; if the obtained user mark information matches the service mark information associated with one of the micro-service modules, determining one of the micro-service modules as a target micro-service module, and sending the access request information to the target micro-service module to ensure that the target micro-service module generates corresponding feedback information; and obtaining the feedback information and returning the feedback information to an official account client. According to the scheme of the invention, by setting a micro-service architecture, the efficiency of official account management and the use experience of the user can be improved.
Owner:CHINA PING AN PROPERTY INSURANCE CO LTD

Grinding wheel automatic dismounting machine containing Teflon sheet and dismounting technology thereof

The invention relates to the field of dismounting of a group of grinding wheels, and especially relates to a grinding wheel automatic dismounting machine containing Teflon sheets. The grinding wheel automatic dismounting machine comprises a stepping conveyor belt, an automatic removing mechanism and a two-stage separation mechanism, the automatic removing mechanism comprises a friction part and aremoving part, the friction part comprises several friction rods, and a charging end of the friction rod close to the stepping conveyor belt, the removing part comprises several removing thin plates,and a middle position of the removing thin plate close to the stepping conveyor belt, a first cylinder is arranged besides the removing thin plate, several positioning tools arranged at intervals along a conveying direction are arranged at a conveying plane of the stepping conveyor belt, a placing groove with an upward opening is arranged at the positioning tool, the positioning tool is in a cuboid structure, first semicircle grooves are respectively arranged at two sides of a width direction of the positioning tool, a third inclined surface is arranged at top of two sides of the placing groove, the Teflon sheet in an entire tool can be automatically and effectively dismounted, so that the integral efficiency is increased, and the technology is simple and reliable.
Owner:金华市国泰砂轮研磨有限公司

Packaging bag unpacking device capable of binding materials

InactiveCN102700785ASolve the unpacking problemEffective splitArticle unpackingReciprocating motionEngineering
The invention relates to a packaging bag unpacking device capable of binding materials. The packaging bag unpacking device mainly comprises a hopper feeding device, a cutting feeding device, a fork, a push rod feeding device and a rack, wherein a hopper is divided into two parts which are in bilateral symmetry and can respectively reciprocate to the two sides; a cutting motor is positioned below the hopper; a packaging bag is cut by a driving tool; the fork can be inserted into the packaging bag, so that a binding band and a material bag are stirred up; and a push rod is used for pushing the unloaded binding band and the material bag out of the hopper. With the adoption of the packaging bag unpacking device, the packaging bag is automatically unpacked, and the materials can be automatically separated from the binding band and the material bag, so that the labor intensity is reduced, and the production efficiency is improved; and in addition, the packaging bag unpacking device can alsobe used for unpacking the packaging bag of powdery materials or granular materials and the like that are not bound.
Owner:BEIJING UNIV OF TECH

Lily bulb core-breaking and segment-splitting equipment

The invention relates to lily bulb processing equipment, in particular to lily bulb core-breaking and segment-splitting equipment. The equipment comprises a bracket, a conveying device, a segment-splitting device, a lifting device and a power device, wherein cutters rotate through motors; the lifting mechanism enables the cutters to move up and down; positioning bowls are arranged on a conveying belt; lily bulbs are placed in each positioning bowl; the inner wall of each positioning bowl is made of food grade soft materials such as food grade silicone, food grade polypropylene and the like; the lower end face of each cutter is a sharp cutting edge; and spiral cutting edges are arranged on the outer wall of each cutter. The equipment utilizes the structural characteristics of the core of the lily bulb and the critical part of the connected scales to perform core breaking and segment splitting, and positioning bowls with different specifications can be matched with cutters with differentspecifications to form different lily bulb core-breaking and segment-splitting devices. The equipment is simple in structure, low in manufacturing and using cost, high in mechanization degree, high in segment-splitting efficiency and small in mechanical damage to the lily bulbs, can effectively split lily bulb segments under one action, and provides a good basis for improving the mechanization and effective processing of the lily bulb industry.
Owner:兰州理工大学技术工程学院

Garbage bag breaking system

InactiveCN104401558AEffective splitConducive to sorting and recyclingBags openingUnpacking by cuttingEngineeringMechanical engineering
The invention discloses a garbage bag breaking system, which comprises a bag breaking tube, a cutting cutter and a motor and is characterized in that the inside of the bag breaking tube is in a tubular shape and is provided with a feeding opening and a discharging opening, a rotating shaft is arranged in the bag breaking tube, the cutting cutter is arranged on the rotating shaft, the motor is connected with the rotating shaft and drives the rotating shaft to rotate, so that the cutting cutter is driven to rotate in the bag breaking tube to cut a garbage bag, the cutting cutter comprises a main cutter and a sub cutter, the main cutter is arranged on the rotating shaft, and the outer end of the main cutter is hinged to the sub cutter. The garbage bag breaking system has the advantages that the rotating cutting cutter is used for cutting the garbage bag entering the bag breaking tube, the cutting cutter has a retreating and avoiding function, and can avoid heavy objects, large objects or substances different to break, the collision generated on the cutting cutter is avoided, the impact on the motor due to cutting cutter stagnation is avoided, the damage to the cutting cutter and the motor is reduced, the service life is prolonged, and the maintenance and overhaul cost is reduced.
Owner:四川洪春福环保设备有限公司

Preparation method of levamlodipine besylate

The invention belongs to the technical field of medicine synthesis, and provides a production method of levamlodipine besylate, which comprises the following steps: using (R, S)-amlodipine besylate asa raw material to react with a resolving agent, and directly reacting with benzenesulfonic acid salt conversion to obtain the levamlodipine besylate, wherein the yield and purity are very good, the used reaction solvent is economic and environment-friendly, and the resolving agent can be further recycled. The method is simple and convenient to operate and does not need special equipment, so thatthe method has a better industrial application prospect.
Owner:LUNAN PHARMA GROUP CORPORATION

HPLC (High Performance Liquid Chromatography) method for dismounting cinacalcet hydrochloride enantiomer

The invention discloses a separation and analysis determination method of a cinacalcet hydrochloride enantiomer. Cellulose-tri(4-methylbenzoate) coated silica gel is selected to be used as a chiral stationary phase; a certain proportion of n-hexane-absolute ethyl alcohol-ethanol amine mixed solvents are used as a flowing phase for separating and analyzing the cinacalcet hydrochloride enantiomer.
Owner:JIANGSU CONSORT MEDICAL TECH CO LTD +1

Virtual land coordinate mapping method and management method based on plane coordinate system

The present invention discloses a virtual land coordinate mapping and management methods based on a plane coordinate system. The technical scheme comprises: taking a point (max_X, min_X) on the x-axisof the plane coordinate system, and taking a point (max_X, min_Y) on the y-axis; and enabling the points to form a rectangular large virtual land with adjacent side lengths of max_X+|min_X|and max_Y+|min_Y|. According to a method of mapping coordinate points in a large virtual land block with the land coordinates in a small virtual land block, in the technical scheme of the present invention, through mutual transformation of plane coordinates and mutual mapping of point-to-plane, point-to-point, and plane-to-point, an infinite number of virtual lands can be produced, a virtual land with an infinite size can be spliced, and the virtual lands can be managed orderly; and the method is simple in algorithm and easy to implement, the search scope can be greatly reduced, query efficiency and management efficiency can be improved, separate rendering can be performed, and the system operation pressure can be reduced.
Owner:重庆强阳科技有限公司

Sowing device

The invention provides a sowing device. The sowing device comprises a seed storage box used for containing seeds, wherein the seed storage box is divided into a seed containing area and a seed sweeping area; the bottom of the seed containing box is provided with a plurality of separation strips at intervals along the length direction; a rotating shaft is mounted in the seed sweeping area; a firstbelt for transporting seeds is arranged between a driving wheel and a driven wheel; the first belt capable of driving the rotating shaft to rotate is further mounted on the driven wheel; the outer surface of the first belt is connected with the separation strips, and the outer surface of the first belt is provided with a plurality of grooves for transporting rice seeds at intervals along the length direction of the first belt; the spacing distances between every two adjacent rows of grooves are equal; and the output end of the first belt is further provided with a seed outlet pipe for conveying the seeds to the field. The scheme can effectively improve the efficiency and precision of rice sowing; and the problem that when the existing machinery performs sowing, sowing is not uniform is avoided; and in addition, the operation is simple and convenient, time and labor are saved, and the seeding requirements of tillage machinery of various types of fields can be met.
Owner:田显才

Microfluidic liquid film chiral separation method

The invention discloses a microfluidic liquid film chiral separation method and relates to a separation method for splitting amino acid racemate. The method comprises the following steps: preparing a microfluidic channel on a PDMS polymerization material, wherein a chiral selective agent and racemate are in a water phase on one side, an organic phase liquid film containing transmitting molecules is in the middle and deionized water on the other side serves as absorbing liquid; splitting the racemate by adjusting the conditions such as the performance and the concentration of the chiral selective agent and the flow quantity of each microfluidic stream. The method is simple in operation and low in energy consumption, the racemate can be split effectively, chiral separation is realized, the use amount of samples and reagents is small, and the cost is reduced.
Owner:CHANGZHOU UNIV

(3S,4R)-4-(fluorophenyl)-3-hydroxymethyl-1-methyl piperidine and split method of antipodism thereof

The present invention discloses a (3S, 4R)-4-(fluorophenyl)-3-hydroxymethyl-1-methyl piperidine and the high-efficiency liquid-phase method for disassembling enantiomers; the chiral column of cellulose category is used to change the n-hexane containing organic alkaline, an organic modifier, into the flow phase; the flow rate of the flow phase is 0.8mL / min. The present invention has good degree of separation.
Owner:BEIJING D VENTUREPHARM TECH DEV

Method used for resolution of equol enantiomers, and measuring of content of equol enantiomers in bean products

The invention discloses a method used for resolution of equol enantiomers, and measuring of the content of equol enantiomers in bean products. The method comprises following steps: 1, bean products to be measured are subjected to pretreatment, wherein methanol extraction and adding of internal standards are adopted; 2, after pretreatment, high performance liquid chromatography-tandem mass spectrometry is adopted to separate and measure equol enantiomers in the bean products to be measured, wherein high performance liquid chromatography conditions are determined as following, a polysaccharide derivative reversely-coated chiral chromatographic column is taken as a chromatographic column, a mobile phase is composed of an A phase and a B phase, the A phase is an ammonium acetate aqueous solution, and the B phase is methyl alcohol. According to the method, high performance liquid chromatography-tandem mass spectrometry is adopted to separate equol enantiomers, optimal analysis conditions are determined via optimization of liquid chromatography parameters, extraction process is simplified, influences of matrix effects are avoided via adding of the internal standards, and the method is capable of avoiding false positive results effectively, and realizing rapid measuring of S-equol in bean products.
Owner:SHANDONG ANALYSIS & TEST CENT

Special needle for implantable drug delivery apparatus

PendingCN110613501AIncrease the force acting surfaceReduce shrinkage elasticitySurgical needlesCatheterSurgeryDrug delivery
The invention relates to a special needle for an implantable drug delivery apparatus. The special needle comprises a needle tube, a needle handle fixed to the needle tube, and an epitaxial tube communicating with the needle tube, wherein the needle tube is fixed to the needle handle, the needle tube communicates with one end of the epitaxial tube, the needle handle is fixed at a joint between theneedle tube and the epitaxial tube, the needle tube comprises a horizontal fixing section and a vertical working section, the fixing section and the working section are connected to form the L-shapedneedle tube, the fixing section of the needle tube is fixed to the needle handle and communicates with the epitaxial tube, the lower end of the working section of the needle tube is smoothly connectedwith an inwardly-bent puncture section through an arc-shaped transition section, the free end of the puncture section is cut through an oblique section to form a puncture tip and a liquid outlet holewith an opening at the side surface, and the oblique section on the puncture needle tip is parallel to the working section of the needle tube, so that a rear cutting edge of the oblique section slides into a puncture port approximately in parallel, the rear cutting edge does not have a cutting effect around the puncture port, cuttings of a punctured matter are avoided to enter the needle tube, and thereby the cuttings are avoided to enter a relevant fluid and then enter the human body.
Owner:郑州迪奥医学技术有限公司

Plane coordinate system-based block chain data management method for virtual parcel

InactiveCN108509809APromote recoveryReduce data concurrency increase problemFinanceDigital data protectionTransaction dataData management
The invention discloses a plane coordinate system-based block chain data management method for a virtual parcel. The block chain data management method comprises virtual parcel division and virtual parcel trading. Through plane coordinate system-based virtual parcel division and block chain data management, trading data management of the virtual parcel gets rid of a "centralization" characteristic; all nodes have effective accurate data and reach a consensus; and even if a central server is subjected to crushing blow such as attack, tampering and the like, the trading data can be quickly retrieved. Moreover, the problem of concurrent increment of various data caused by connection between each node and the server is greatly reduced.
Owner:重庆强阳科技有限公司
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