48 results about "Parotid gland" patented technology

This invention relates to improved uses of botulinum neurotoxins in the treatment of sialorrhea or diseases or conditions relating to increased saliva production. In particular are botulinum neurotoxins disclosed which are administered into parotid and submandibular glands in a dose ratio between 1.45 to 1 and 1.7 to 1.

The invention discloses a transgenic vector of salivary gland tissue specific expression foreign protein and a construction method thereof; the expression vector is constructed by inserting a recombinant fusion gene constructed by glucanase gene, xylanase gene, and phytase gene into a parotid gland-specific transgenic vector; the vector is introduced into pig genome, and transgenic pigs is produced by a somatic cell nucleus transplant technique. The transgenic vector of the invention has hydrolytic action on glucanase in barley raw materials, xylanase in wheat and corn, and phytase in vegetable feed; the pig salivary gland is used as a reactor to realize secretion for the whole life; the addition of the enzyme preparations into feed is replaced permanently, which gives better play to the enzymes; the expression vector of the invention has a piggyback transposon, which greatly increases the transgenosis efficiency, changes the transgenic integration model of common plasmid serial recombination into single locus single copy integration, and thus better simulates the internal environment of biological genes.

The invention discloses a salivary gland tissue specific transgenic carrier and a construction method thereof. The salivary gland tissue specific transgenic carrier is obtained by emerging an upstream regulation region sequence of a mice parotid gland protein promoter and a visual screened neo-EGFP combined double-label to a piggyBac transposon system and a Lox-Cre enzyme system; the transgenic carrier can make protein express in a particular tissue to achieve a high-efficient large-section emerging efficiency. The carrier also has a green luminescence label which is convenient for screening and a neomycin resistance gene which is convenient for eukaryotic cell screening, and makes the screening of transgenic cells and identification of transgenic animals be simpler, more direct, and more accurate. The transgenic carrier provided by the invention is a salivary gland specific expression high-efficient integration universal carrier, and is capable of being applied to fields of transgenic animals such as transgenic mice and pig, and the like. The invention clones the upstream regulation region of FVB mice for the first time, the cloning method is simple and high efficient, and the difficulty in construction of a large section carrier is effectively overcome.

The externally applied Chinese herbal medicine for treating mammary cancer and lumph cancer is prepared with 11 kinds of Chinese medicinal materials, including frankincense, myrrh, dragon's blood, catecu, angelica, etc. The externally applied Chinese herbal medicine may be used to treat mammary cancer, lumph cancer, carcinoma of parotid gland and other malignant tumors in epithelial tissue, and has fast acting, high curative rate, no pain and no toxic side effect.

The Chinese medicine plaster for external application for curing pharyngitis, tonsillitis, laryngitis and parotitis is made up by using 18 Chinese medicinal materials of ledebouriella root, lonicera flower, forsythia fruit, dried / fresh rehmannia root, scrophularia root, ophiopogon tuber and others through a certain preparation process. Said medicine plaster possesses the functions of expelling wind, clearing heat, removing toxic substances, relieving sore-throat, reflenishing yin essence and moisturizing the viscera, reducing phlegm and resolving masses, and is non-toxic, and has no any side effects. On every plaster carrier 0.1-0.6g of the medicine powder is applied to obtain the invented product.

The invention discloses paste for treating epidemic mumps and a method for preparing the paste. The paste comprises cactus squeezed liquid, aloe squeezed liquid, honeysuckle extract liquid, peppermint extract liquid, cortex dictamni extract liquid, wild chrysanthemum extract liquid, scutellaria baicalensis extract liquid, aloe oil, borage oil, calendula oil, glycerin, ethylparaben, water-soluble Ve (vitamin E), omnipotence emulsifiers G57, ice crystal forming agents AVC and distilled water. Compared with the prior art, the paste and the method have the advantages that the paste is mild in medicine property and high in safety, excellent epidemic mumps treatment effects can be realized by active substances in natural medicines, and obvious effects of diminishing inflammation and swelling, clearing heat, removing toxicity, promoting blood circulation to remove blood stasis and dredging parotid gland meridians can be realized by the paste; the paste is locally applied and is safe in use, free of side effects, high in osmosis and durable in efficacy, obvious treatment effects for improving the mumps can be realized if the paste is used for a long time, symptoms and root causes can be treated, and accordingly patients can be kept away from the mumps; excellent prevention effects can be realized by the paste.