The invention discloses an anti-inflammatory and pain-relieving ointment and a production process thereof. It is made from rhubarb, nuxychnium extract, frankincense, myrrh, borneol, and xuanming powder. Make compound rhubarb extract from frankincense, myrrh and rhubarb; put the medical carrier jelly base and auxiliary materials into the batching tank, heat until melted, or cut rubber into thin slices, soak in gasoline, and wait for the rubber to swell completely Finally, put it into the glue barrel and stir evenly, then add zinc oxide, vaseline, and lanolin and stir evenly to make a matrix; add compound rhubarb extract, nuxe chamomile extract, xuanming powder crushed into fine powder and borneol Matrix, filter, coat, cut, cover membrane. All medicines of the whole prescription of the present invention are used in combination to promote blood circulation and remove blood stasis, promote qi and dissipate stagnation, clear heat and detoxify, reduce swelling and relieve pain, and can treat acute and closed soft tissue injuries, cervical spondylosis, psoas muscle and vertebral aponeurosis caused by bruises. Diseases have significant curative effect. For local external use, the medicine has strong penetrating power, anti-inflammatory and analgesic effect quickly, and it can take effect within a few hours, and has the effects of moisturizing the skin and treating both the symptoms and the root causes.