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Composition for treating sicca syndromes and patterns/syndromes of yin deficiency and preparation method and application of composition

A technology for Sjögren's syndrome, yin deficiency and blood stasis, applied in drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve dry mouth symptoms with no obvious curative effect, no good treatment methods, liver and kidney function damage and other issues, to achieve the effect of unique formula, reducing economic burden and improving symptoms of patients

Inactive Publication Date: 2019-03-29
JIANGSU PROVINCIAL HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Sjögren's syndrome is a disease with advantages and characteristics in the treatment of traditional Chinese medicine. Because there is no good treatment method, Western medicine mainly uses hormones and immunosuppressants, or stimulates glandular secretion with anetisone, but the effect on dry mouth symptoms is not obvious , and long-term use may cause side effects such as osteoporosis, induction or aggravation of infection, metabolic disorder, liver and kidney function damage

Method used

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  • Composition for treating sicca syndromes and patterns/syndromes of yin deficiency and preparation method and application of composition
  • Composition for treating sicca syndromes and patterns/syndromes of yin deficiency and preparation method and application of composition
  • Composition for treating sicca syndromes and patterns/syndromes of yin deficiency and preparation method and application of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Party:

[0028] 5 parts of wolfberry, 3 parts of chrysanthemum, 3 parts of cassia seed, 6 parts of Ophiopogon japonicus, 6 parts of Passepartout, 5 parts of white peony, 5 parts of dendrobium, 3 parts of dark plum, 3 parts of hawthorn, 3 parts of turmeric, 2 parts of licorice.

[0029] Preparation:

[0030] Raw material processing: put chrysanthemum in a container, spray it with 75% edible ethanol, and seal it for 1 hour; put medlar, cassia seed, Ophiopogon japonicus, Passepartout, white peony root, dendrobium, black plum, burnt hawthorn, turmeric, and licorice in a pulsating vacuum In the pressure steam sterilizing cabinet, feed steam, keep at 105°C for 40 minutes, and dry the processed raw materials at 60-70°C.

[0031] (1) Extraction: add Ophiopogon japonicus, Passepartout, black plum, Jiaohawha, and turmeric to 6 times the amount of water (equivalent to the weight of the decoction pieces), soak for 60 minutes, fry for 2 times, each time for 1 hour, and filter.

[...

Embodiment 2

[0038] Party:

[0039] 15 parts of wolfberry, 15 parts of chrysanthemum, 9 parts of cassia seed, 15 parts of Ophiopogon japonicus, 20 parts of Passepartout, 20 parts of white peony, 20 parts of dendrobium, 15 parts of black plum, 15 parts of hawthorn, 15 parts of turmeric, 10 parts of licorice.

[0040] Preparation:

[0041] Raw material processing: put chrysanthemum in a container, spray it with 75% edible ethanol, and seal it for 1 hour; put medlar, cassia seed, Ophiopogon japonicus, Passepartout, white peony root, dendrobium, black plum, burnt hawthorn, turmeric, and licorice in a pulsating vacuum In the pressure steam sterilizing cabinet, feed steam, keep at 105°C for 40 minutes, and dry the processed raw materials at 60-70°C.

[0042] (1) Extraction: add Ophiopogon japonicus, Passepartout, black plum, Jiaohawha, and turmeric to 6 times the amount of water (equivalent to the weight of the decoction pieces), soak for 30 minutes, fry for 3 times, each time for 1 hour, and f...

Embodiment 3

[0049] Party:

[0050] 10 parts of medlar, 10 parts of chrysanthemum, 6 parts of cassia seed, 10 parts of Ophiopogon japonicus, 6 parts of black plum, 15 parts of Passepartout, 10 parts of white peony, 9 parts of dendrobium, 6 parts of licorice, 10 parts of turmeric, and 9 parts of hawthorn.

[0051] Preparation:

[0052]Raw material processing: put chrysanthemum in a container, spray it with 75% edible ethanol, and seal it for 1 hour; put medlar, cassia seed, Ophiopogon japonicus, Passepartout, white peony root, dendrobium, black plum, burnt hawthorn, turmeric, and licorice in a pulsating vacuum In the pressure steam sterilizing cabinet, feed steam, keep at 105°C for 40 minutes, and dry the processed raw materials at 60-70°C.

[0053] (1) Extraction: add Ophiopogon japonicus, Passepartout, black plum, Jiaohawha, and turmeric to 6 times the amount of water (equivalent to the weight of the decoction pieces), soak for 30 minutes, fry for 3 times, each time for 1 hour, and filte...

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Abstract

The invention discloses a composition for treating sicca syndromes and pattern / syndromes of yin deficiency and a preparation method and application of the composition. The composition comprises the following raw materials in parts by weight: 5-15 parts of lycium barbarum, 3-15 parts of chrysanthemum flos, 3-9 parts of cassia seeds, 6-15 parts of radix ophiopogonis, 6-20 parts of beautiful sweetgumfruits, 5-20 parts of white peony roots, 5-20 parts of dendrobe, 3-15 parts of smoked plums, 3-15 parts of hawthorns, 3-15 parts of turmeric and 2-10 parts of licorice roots. The composition is unique in formula, is composed of multiple traditional Chinese medicines for nourishing yin, generating body fluids and activating blood, has the functions of generating body fluids and moistening drynessas well as promoting blood circulation and removing meridian obstruction, is reasonable in dosage form and is convenient to take after being made into a tea preparation, and medicines can directly acton tongues, oral mucosae and parotid gland ends to alleviate symptoms, and have long-lasting actions after being absorbed; in addition, the composition disclosed by the invention is made of common traditional Chinese medicines and is low in price, so that patients have low economic burden, and good social benefits and economic benefits can be achieved.

Description

technical field [0001] The invention belongs to the technical field of drugs for treating Sjögren's syndrome and yin deficiency and blood stasis syndrome, and specifically relates to a composition for treating Sjogren's syndrome and yin deficiency and blood stasis syndrome, a preparation method and application thereof. Background technique [0002] Primary sjogren's syndrome (SS) is a systemic autoimmune disease that can involve exocrine glands, lungs, kidneys, joint muscles, nerves and other tissues and organs. The parotid gland is the most common damaged target organ of SS, manifested as dry oropharynx, enlarged and hard parotid gland. Sjogren's syndrome is a disease with advantages and characteristics in the treatment of traditional Chinese medicine. Because there is no good treatment method, Western medicine mainly uses hormones and immunosuppressants, or stimulates glandular secretion with anetthio, but the effect on dry mouth symptoms is not obvious , and long-term us...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P31/14A61P37/02
CPCA61K36/815A61K36/185A61K36/287A61K36/482A61K36/484A61K36/65A61K36/71A61K36/734A61K36/736A61K36/8968A61K36/8984A61K36/9066A61K2236/331A61K2236/51A61P31/14A61P37/02A61K2300/00
Inventor 陈剑梅钱先郭峰刘志辉史潇璐
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM
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