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The present invention provides a nano-micellar preparation containing vinca alkaloids antitumor agent for intravenous injection, which cincludes a therapeutically effective amount of vinca alkaloids antitumor agent (vinblastine, vincristine, vindesine and vinorelbine), a phosphatide derivatized with polyethylene glycol, together with pharmaceutically acceptable adjuvants. The preparation is prepared by encapsulating the medicament with a nano-micelle to obtain the nano-micellar preparation containing vinca alkaloids antitumor agent for injection. The vinca alkaloids antitumor agent and the phosphatide derivatized with polyethylene glycol form a nano-micelle with a highly uniform particle size. In the micelle, the hydrophobic core of encapsulated medicament is surrounded by polyethylene glycol molecules to form a hydrophilic protective layer, so that the medicament is prevented from contacting with the enzymes and other protein molecules in blood and being recognized and phagocytozed by reticuloendothelial system in body, and the circulation time in vivo of the micelle is prolonged.

The invention discloses a high-precision data recording time service instrument. A GPS time-service plate receives the second pulse information of precision and absolute time information through an antenna; the information is then transmitted to a recording control plate and corrects an internal clock in the control plate; strict synchronisation between the control plate and the absolute time is kept; the recording control plate is respectively connected with the equipments to be recorded and a user data collecting computer through communication cables; the user data is received and the commands emitted by a computer is collected in accordance with a communication protocol; the state of the GPS receiver and GPS time and position information are fed back to the user data collecting computer; the communication rate and data frame format of the equipment to be recorded are arranged; the communication with the equipment to be recorded is established; the time-service instrument is convenient to be carried, can work in all areas with GPS satellite signals, is used for providing asynchronous series testing interfaces for the time-service precision requirement of 1 multiplied by 10<-4> seconds; furthermore, the communication rate is 38400bps. The invention is used for testing the true-value equipments which has fixed testing frame length and 38400bps of signalling rate and recording the output data of the equipment to be tested.

A material comprising a novolac resin having a C6-C30 aromatic hydrocarbon group substituted with a sulfo group or an amine salt thereof is useful in forming a photoresist undercoat. The undercoat-forming material has an extinction coefficient sufficient to provide an antireflective effect at a thickness of at least 200 nm, and a high etching resistance as demonstrated by slow etching rates with CF4 / CHF3 gas for substrate processing.

The ionizer includes a nozzle having a discharge electrode for inducing corona discharge by application of high voltage to eject ions, an emission port for emitting supplied gas together with the ejected ions, and a gas channel for guiding supplied gas to the emission port. Herein, a velocity of flow of the gas immediately after emission from the emission port exceeds a velocity of sound, and a gas pressure at the emission port is not less than an atmospheric pressure. The gas channel has a throat part for narrowing the gas channel such that a channel area gradually decreases, and a ratio of the atmospheric pressure to a gas pressure at a position where the channel area does not vary, the position being located forward of the throat part, is not more than 0.528.