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315 results about "Caprylates" patented technology

Derivatives of caprylic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a carboxy terminated eight carbon aliphatic structure.

Chromatographic method for high yield purification and viral inactivation of antibodies

An improved process for the purification of antibodies from human plasma or other sources is disclosed. The process involves suspension of the antibodies at pH 3.8 to 4.5 followed by addition of caprylic acid and a pH shift to pH 5.0 to 5.2. A precipitate of contaminating proteins, lipids and caprylate forms and is removed, while the majority of the antibodies remain in solution. Sodium caprylate is again added to a final concentration of not less than about 15 mM. This solution is incubated for 1 hour at 25° C. to effect viral inactivation. A precipitate (mainly caprylate) is removed and the clear solution is diluted with purified water to reduce ionic strength. Anion exchange chromatography using two different resins is utilized to obtain an exceptionally pure IgG with subclass distribution similar to the starting distribution. The method maximizes yield and produces a gamma globulin with greater than 99% purity. The resin columns used to obtain a high yield of IgG retain IgM and IgA. IgA and IgM may be eluted from these resins in high yield and purity.
Owner:BAYER HEALTHCARE LLC

Watersoluble fluor resin non-stick paint and manufacture method thereof

InactiveCN101245209AHigh hardnessGood temperature distribution areaSpecial surfacesEmulsion paintsWater basedPerfluorooctanoic acid
The invention relates to a waterborne fluororesin nonstick coating, which is formed by 40 to 70 portions of modified polyte-trafluoroethylene (PTFE) water base resin, 10 to 30 portions of high temperature resistance pigment, 1 to 5 portions of fluororesin additive, 1 to 5 portions of surfactant and 20 to 40 portions of antiwear filler. The waterborne fluororesin nonstick coating uses synthesis propylene acid water base resin for modifying trafluoroethylene PTFE water base resin, adopts acrylic acid fat second polymerization method and does not use an addition agent, the entire fluorine caprylate compound which is harmful to human body in the modification process; the modified resin forms mosaic and perforating network structure, has good temperature dispersing region, solves the problem of the adhesiveness of the coating and the base material and the problems of baking and cracking, thus improving the hardness of nonstick coating. The NU aqueous fluorine resin of the invention does not stick to coating, can be coated on the surfaces of a microwave oven, an electric cooker, a nonstick pan and an electromagnetic pan, etc. to play the roles of protecting the surfaces from being stuck with food, and causing food and aluminum and other metals to be isolated.
Owner:TIANJIN COLOROAD COATING & CHEM

Double-layer essence with repair and anti-aging functions, method for preparing double-layer essence and application thereof

The invention belongs to the technical field of cosmetics, and particularly discloses double-layer essence with repair and anti-aging functions. The double-layer essence comprises, by weight, 1.0%-2.0% of PEG-40 (polyethylene glycol-40) hydrogenated castor oil, 5%-19% of methyl trimethicone, 4%-6% of dicaprylyl carbonate, 0.5%-1.5% of cetyl dimethicone, 0.5%-1.5% of helianthus annuus seed oil, 3%-9% of glycerin, 0.1%-0.15% of sodium hyaluronate, 0.5%-1.5% of myrothamnus flabellifolia leaf/stem extract, 1%-3% of polypeptides with palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, 0.5%-1.5% of lactobacillus ferment lysate, 1%-3% of glycosphingolipid, 0.8%-1% of mixtures of glycerol caprylate, p-hydroxy phenyl ethyl ketone and glyceryl laurate and the balance water. The double-layer essence has the advantages that the double-layer essence which is a novel ultralow-viscosity double-layer system is unique in structure and convenient to use; formulas and structures of the double-layer essence are optimized, and accordingly the double-layer essence is free of potential irritation and allergy sources such as perfume and preservatives, is in mild and non-irritant formulas and has the excellent repair and anti-aging functions.
Owner:GUANGDONG MARUBI BIOLOGICAL TECH CO LTD

Anticorrosive component-free composition having antibiosis effect, and preparation method and application thereof

ActiveCN107432834AHas activity against Gram bacteriaSynergistic sterilizationAntibacterial agentsCosmetic preparationsCaprylyl GlycolCAPRYLHYDROXAMIC ACID
The invention discloses an anticorrosive component-free composition having an antibiosis effect. The composition comprises, by weight, 20-45% of p-hydroxyacetophenone, 3-10% of glycerol caprylate, 6-15% of caprylhydroxamic acid, 21-40% of propylene glycol, 0.5-1.5% of caprylyl glycol and 5-15% of ethylhexylglycerin, and the sum of the weight percentages of all above components is 100%. The anticorrosive component-free composition having the antibiosis effect has the advantages of no irritation, non-allergy, protruding antibiosis effect, harmlessness to human bodies, and no toxic or side effects, and can be safely applied to cosmetics. The invention also discloses a preparation method of the anticorrosive component-free composition having the antibiosis effect. The preparation method of the composition has the advantages of few steps, simple flow, and safety in operation. The invention further discloses an essence and a preparation method thereof. The essence has the advantages of good antibiosis effect, wide antibiosis range, no toxicity, harm or irritation, and high use safety, and the preparation method of the essence has the advantages of few steps, simple flow, and safety in operation.
Owner:广州市皓雨化妆品有限公司

Multiple-plant-extract lip pomade and preparation method thereof

The invention discloses multiple-plant-extract lip pomade and a preparation method thereof. The multiple-plant-extract lip pomade contains the following raw materials in parts by weight: 19 parts of olive squalane, 14 parts of diisostearyl alcohol malate, 5 parts of dimeric pentaerythritol tri-polyhydroxyl stearate, 5 parts of jojoba esters, 5 parts of tridecanol trimellitate, 5 parts of caprylate / decanoate triglyceride, 5 parts of meadowfoam seed oil, 5 parts of adansonia digitata tree seed oil, 5 parts of phytosterol oleate, 5 parts of C10-30 acid cholesterol / lanosterol mixed ester, 4 partsof polyethylene, 3 parts of candelilla wax, 3 parts of hydrogenated castor oil dimeric linoleate, 3 parts of polyglycerol-2-tri-isostearate, 2.5 parts of beeswax, 2.5 parts of earth wax, 4 parts of humectant, 2 parts of emollient, 2 parts of prunus avium seed oil, 0.5 part of tocopherol and 0.5 part of antioxidant. The multiple-plant-extract lip pomade has very good repairing, moisture preservingand cheilogramma dispelling actions and can be used for durably nourishing and relaxing skin and keeping lip skin healthy.
Owner:广州尚姿化妆品有限公司

Repairing eye cream with anti-blue-light effect and preparation method thereof

The invention provides a repairing eye cream with an anti-blue-light effect and a preparation method thereof. The repairing eye cream with the anti-blue-light effect is prepared from the following functional components of glycerol, butanediol, EDTA disodium, avocado butter, cetostearyl alcohol, isopropyl myristate, bis-PEG-18 methyl ether dimethyl silane, neopentyl glycol dicaprylate, DC9040 silicon elastomers, a MONTANOV68 emulsifier, a thickening agent SEPINOVEMT10, an emulsifying agent SIMULSOL165 and deionized water, wherein the functional components comprise xanthophyll, a bifidus yeast fermentation product spore lysate, acetyl hexapeptide-8, acetyl tetrapeptide-5, palmitoyl pentapeptide-4, a cocoa seed extract, nicotinamide, a centella asiatica extract, borneol, zinc carbonate hydroxide, amber powder, pearl powder, borax, tocopheryl acetate, glucosyl hesperidin, allantoin and fullerene. The repairing eye cream with the anti-blue-light effect not only has the effect of resisting blue light invasion, but also has the repairing effect, and is high in application prospect.
Owner:WUHAN MAYINGLONG MASSIVE HEALTH CO LTD

Dendritic grafted polycaprolactone

The invention discloses an arborescent graft polycaprolactone, and also discloses an arborescent graft polycaprolactone-polyethylene glycol copolymer and application of the copolymer as a drug carrier. In the invention, a novel arborescent graft polycaprolactone-polyethylene glycol copolymer is prepared by preparing a new epsilon-caprolactone derivative (4-benzyloxy-ethoxy-epsilon-caprolactone; BECL) from 1,4-cyclohexanediol used as a raw material, then carrying out ring-opening copolymerization on the BECL and epsilon-caprolactone in the presence of stannous iso-caprylate used as a catalyst, carrying out palladium-carbon catalytic hydrogenation to remove benzyl protecting groups to obtain the arborescent graft polycaprolactone with multiple hydroxyl groups, and finally grafting and introducing hydrophilic polyethylene glycol chain segments to the hydroxyl groups with phosgene as a chain extender. In an aqueous medium, the hydrophobic arborescent graft polycaprolactone shrinks to forma core, and the hydrophilic polyethylene glycol chain segments stretch at the periphery, thus forming a unimolecular micelle. As a drug carrier, the micelle has the advantages of large drug carrying capacity and good stability.
Owner:WUHAN UNIV

Preparation method of (R)-(+)-lipoic acid

The invention discloses a preparation method of (R)-(+)-lipoic acid and belongs to the field of organic and medicinal chemistry. The preparation method comprises the following steps: (S)-ethyl 6,8-dichloro caprylate and sulfur are fed into a reaction container equipped with a stirring device, the mixture is heated, an aqueous sodium sulphide solution is added dropwise for a cyclization reaction, heat is preserved, then extraction and concentration are performed, and a cyclization liquid is obtained; the cyclization liquid is fed into the reaction container, an alkaline solution is added, a hydrolysis reaction is performed, and a hydrolysate is obtained through cooling; an organic solvent is added to the hydrolysate, pH is regulated with acid, extraction is performed, an organic layer obtained through extraction is washed to be neutral, then an organic solvent is removed through pressure reduction, a primary product is obtained, a mixed solvent is added to the primary product, the mixture is heated and dissolved, a filter aid is added, stirring and adsorption are performed, filtering is performed, a faint yellow liquid is obtained and cooled, crystals are precipitated, and a finished product is obtained. The steps are reduced, and the preparation efficiency is high; raw material consumption is reduced, the optical rotation of (R)-(+)-lipoic acid reaches 117-118 degrees, the ee value is 99.0%-99.5%, the content is higher than 99%, and waste emission is reduced.
Owner:SUZHOU FUSHILAI PHARMA CO LTD
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