55 results about "Antibiotic products" patented technology

The invention discloses a making method of antibiotic product of surface through physical gas-phase sediment technique, which comprises the following steps: plating antibiotic target or evaporating material on the base surface to form antibiotic coater through physical gas-phase sediment technique; allocating the antibiotic target or evaporated material with one or more component of Ti, Zn, Ca, Si, Mg, Zr, Cd, As, Sb, Se, Ce, Re, Cu, Ag, Pb, Hg, Co, Ni, Al, Fe and their oxide, sulfate, nitride and carbonate; aerating O2, N2, NH3, CH4, C2H6 or H2S as reacting gas.

The invention discloses a fermentation type botanical weaned piglet feed additive. The feed additive is obtained through mixing a component A, a component B and a component C, wherein the component A is prepared through crushing and fermenting Moringa tree leaf, Eucommia ulmoides, Radix Astragali, Radix Codonopsis, Manyprickle Acathopanax Root, honeysuckle flower, licorice root and Herba Taraxaci; the component B is prepared through crushing and mixing purslane, hawthorn fruit and pine needle powder; and the component C is prepared through mixing an Origanum vulgare extract and aloe polysaccharides. The feed additive prevents diarrhea, effectively improves the immunities of piglets, avoids the use of antibiotic products, can completely substitute antibiotic medicines, solves a stress problem of weaned piglets, effectively improves the immune functions of the piglets, reduces the disease incidences and the mortality, and guarantees the gastrointestinal tract health of the weaned piglets, so the production performance and the culturing benefit of the weaned piglets are improved.

The invention discloses a pig feed additive which belongs to the field of feed and relates to a feed additive. The pig feed additive comprises the following components in parts by weight: 10-25 parts of yeast extract, 10-18 parts of high-temperature resistance lactic acid bacteria, 5-10 parts of soybean peptide, 8-18 parts of ganoderma fruiting body, 5-15 parts of bran, 10-22 parts of cordyceps mycelia, 1-3 parts of fructose-oligosaccharide, 1-4 parts of raffinose, 1-3 parts of cellulase, 1-2 parts of protease, 1-3 parts of mixed amino acids and 0.5-2 parts of amino acid chelated copper. After being compounded, the pig feed additive has the advantages of having very good anti-diarrhea effect, effectively enhancing the immunity of piglets, reducing the application amount of antibiotic products and improving the growth quality of the piglets; and through application of the pig feed additive, the phenomena that the piglets have long hair in a nursing stage, and the growth and development of the pigments are hindered after the nursing stage are avoided.

The invention relates to a high-efficiency monatomic silver nanowire antibiotic material which is characterized in that the monatomic silver nanowire of the antibiotic material extends from the orifice of a framework-doped manganese dioxide molecular sieve into a hole. The manganese dioxide molecular sieve is characterized by being of a hollandite type crystal structure; and the hole contains the monatomic silver nanowire or / and A ions (A=K<+>, Na<+> or H<+>). The chemical general formula can be expressed as Agm(A)n[MxMn8-x]O16 (M=Mn<2+> / <3+>, Zn<2+> and Ti<4+>; A=K<+>, Na<+> or H<+>; m<=3; n<=2; and x<=2), [MxMn8-x]O16 represents the framework composition of the manganese dioxide molecular sieve, and Agm(A)n represents the hole composition of the manganese dioxide molecular sieve. By mainly using the sterilization mechanism of catalytic activated oxygen, silver of the monatomic silver nanowire antibiotic material is not consumed in the sterilization process. Based on the synergetic effect of the quantized monatomic silver nanowire and the hollandite type manganese dioxide molecular sieve, the antibiotic material has extremely high oxygen activation performance, thereby leading to long-acting, high-efficiency and stable broad-spectrum antibiotic capability and having no adverse side effect on a human body. Thus, the antibiotic material can be widely used for preparing various antibiotic products such as paint, plastic, rubber, textile and the like.

The invention discloses compound feed for piglets, belongs to the field of livestock breeding and particularly relates to a compound feed in a piglet stage. The compound feed for piglets comprises the following ingredients in parts by weight: 18 to 22 parts of hulled corn, 12 to 15 parts of puffed corn, 8 to 12 parts of whey powder, 4 to 5 parts of fish meal, 2 to 3 parts of glucose, 2 to 3 partsof blood plasma powder, 0.012 to 0.015 parts of phytase, 0.4 to 0.5 parts of monocalcium phosphate, 0.03 to 0.05 parts of choline chloride, 0.2 to 0.4 parts of lysine and the like. The feed has the advantages that a good anti-diarrhea effect can be reached, meanwhile, the piglet immunity is effectively improved, the use of antibiotics products is reduced, the piglet growth quality is improved, and the basis is laid for the realization of the piglet reproduction potential; meanwhile, phenomena of virtual growth of the piglets in the nursing stage and growth development blockage after the nursing stage are avoided; and the environment pollution is reduced.

The invention provides an antibiotic fiber. The antibiotic fiber comprises, by weight, 20-30% of chitosan, 3-5% of a dispersant, 5-10% of a fusogen, 2-5% of a grafting modifier, and the balance PET. The invention also provides a preparation method of the antibiotic fiber, and a pillow core and a quilt core containing the antibiotic fiber as a filling material. Present antibiotic products have safety performance problems and defects which are not adapted to industrial production, so the antibiotic fiber of the invention which can highly effectively inhibit more than twenty harmful bacteria of escherichia coli, staphylococcus aureus, Candida albicans and the like with an average bacteriostasis rate of equal to or more than 98%, and can not generate side effects to beneficial flora in human bodies has the effect of ecological bacteriostasis, and is adapted to industrial production.

The invention relates to a house-fly pupa natural antibiotic peptide product as well as a preparation method and application thereof; house-fly pupas, the raw material of the antibiotic peptide product, are extracted overnight by acid and hot-processed to collect supernatant; and after going through siever filtration and ultrafiltration precessing, the supernatant is treated with spray dring to obtain the antibiotic peptide product. The preparation technique of the antibiotic peptide product is simple and quick, the yield of the antibiotic peptide reaches 1.2 percent and the recovery rate of the antibacterial activity is over 80 percent. The prepared house-fly antibiotic product consists of peptides which have the molecular weight less than 20kDa and are mainly micromolecular peptides with the molecular weight less than 14.4 kDa. The antibiotic peptide product has broad-spectrum antibiotic activity and no hemolytic activity to blood erythrocytes of mice and is characterized by high temperature resistance, acid and alkali resistance and good stability. The byproducts of the technique can serve as feeding insect protein powder. The prepared antibiotic peptide product can be widely applied to the fields such as the antisepsis and storage of foods, fruits and vegetables, feed additives, cosmetic and the like.

This invention relates to a method for manufacturing surface anti-bacterium product by a physical gas phase deposition technology including utilizing the physical gas phase deposition technology to plate an anti-bacterium target material on a matrix surface to form a film, characterizing in drilling small air holes on said anti-bacterium target and penetrating reaction gas by windpipes, in which, said target is made of As, Se, Hg, Ag, Cu, Zn, CE, Ca, Co, Ni, Al, Fe, S and their oxides, which drills holes on the target surface to prevent the target from poisoning to realize multi-arc plating and magnetic controlled sputtering plating.

The mildew-proof antibiotic polyurethane sponge is prepared with polyol 46.59-78.85 wt%, toluene diisocyanate 19.33-39.2 wt%, water 0.95-3.16 wt%, silicone oil 0.63-1.5 wt%, tin caprylate 0.08-0.19 wt%, amine catalyst 0.06-0.12 wt%, 2, 4, 4'-trichloro-2'-hydroxy-diphenyl-ether 0.01-5 wt%, 2-thiazolyl-4-benzimidazole 0.01-5 wt%. With mildew-proof antibiotic chemicals added, the mildew-proof antibiotic polyurethane sponge may be used in making different kinds of healthful mildew-proof antibiotic products.

The invention provides a pig feed additive for effectively improving intestinal health and enhancing immunity and belongs to the field of feed additives. The additive consists of saccharicterpenin, a snakegourd fruit extract, a compound amino acid chelate, a compound enzyme preparation, turmeric root-tuber, trogopterus dung, catechu powder, grassleaf sweelflag rhizome, frankincense powder, milkvetch root, white paeony root, Chinese lizardtail rhiaomeor herb, sorbic acid, stachyose, magnesium stearate and a carrier, wherein the carrier comprises corncob powder and zeolite powder. By adopting the additive provided by the invention, the intestinal health of pigs can be improved, the immunity of the pigs can be effectively improved, the consumption of antibiotic products can be reduced, a foundation for achieving the productive potential of piglets can be laid, the reduction of breeding risks can be facilitated, and the breeding benefits can be enhanced.

The present invention provides hemostatic and antibacterial products, including solution, dressing and bandage. The hemostatic and antibacterial products contains setose thistle herb extract in 1-30.61 wt%, zephiran chloride in 0.1-0.5 wt%, and optional local anesthetic in 1-2 wt% and / or surfactant in 0.1-0.5 wt%. The production process of the hemostatic and antibacterial products is also provided.

This invention relates to a moisturizing skin ointment composition consisting of polymyxin B Sulfate, bacitracin zinc, neomycin (the combination of which totals 1 ounce), hydrocortisone acetate (1 ounce) and white petrolatum (13 ounces). When combined and water evaporated, an external ointment that penetrates the skin and alleviates dry skin conditions, itching and minor scrapes and scratches is created. The properties of the antibiotic products help to promote healing of minor scrapes and scratches as well as preventing the spread of dry skin conditions. The properties of the hydrocortisone aids in the alleviation of itching associated with dry skin. Because this ointment penetrates the dermis almost immediately, the moisturizing properties of petrolatum allows the full benefit of the antibiotic products and hydrocortison to remain on / in the skin through several washings thereby alleviating the need to reapply several times a day.

The invention discloses a multifunctional plant composition which is characterized by comprising senecio plants, verbenaceae plants, solanum plants and serissa plants. Aiming at the limit of chemically synthesized antibiotic products, the invention provides a skin and mucosa antibiotic composition prepared from natural active matters, and the composition can effectively prevent and cure pathological changes of the skin and the mucosa of the human body, which is caused by bacteria or fungi. The invention has the advantages of environmental protection, no irritation, long-time and large-area use, strong antibiotic and antipruritic capacity, quick response, simple preparation process, low cost, and the like.

The invention belongs to the related technical field of veterinary drug antibiotic products, and particularly relates to a high-water-solubility tylvalosin premix. An tartaric acid tylvalosin bulk drug, anhydrous DL-tartaric acid, caramel pigment (food grade) and maltodextrin are added for supplement; and uniformly mixing and sub-packaging to obtain the 20% tartaric acid tylvalosin premix. The water solubility of the tartaric acid tylvalosin premix is obviously improved, and meanwhile, the long-term storage stability can be ensured. The water solubility of the prepared tylvalosin premix is increased from 7000 to 8000 ppm to more than 20000 ppm on the basis of pure tartaric acid tylvalosin. In the accelerated test for long-term storage stability, the tylvalosin premix is sealed with a transparent plastic bag and stored in a constant temperature and humidity chamber (40 DEG C, relative humidity of 75%) for 6 months, and the tylvalosin premix is not caked and discolored and is detected to be qualified according to the national standard.

The invention belongs to the field of medicines, and discloses novel application of a nauclea officinalis extract, in particular application of the nauclea officinalis extract to preparation of a propionibacterium acne inhibitor. Experiments show that the nauclea officinalis extract has propionibacterium acne inhibiting activity and can inhibit growth of propionibacterium acnes, so that the nauclea officinalis extract can be applied to preparation of the propionibacterium acne inhibitor and preparation of medicines for treating the acnes and cosmetics for improving the acnes and has a relatively high application value and a relatively high development prospect; in addition, the nauclea officinalis extract uses a natural material, so that the side effects caused by the conventional antibiotic products to a human body can be avoided.

The invention discloses a preparation method of laying hen granular powder with added plant essential oil, and belongs to the technical field of feed and preparation methods thereof. Plant essential oil compounds including thymol, carvacrol, eucalyptus oil, cinnamyl aldehyde and citral are designed and added on the basis of feeding laying hens with granular powder. The laying hen granular powder is free of drug resistance and high in safety, can effectively replace antibiotic products, and conforms to the development direction of current healthy breeding. Meanwhile, by performing low-temperature coating treatment on the plant essential oil, the volatilization loss in the packaging, storage, transportation and use processes is reduced, the adsorption of feed raw materials to the plant essential oil is avoided, and the stability of the use effect of the plant essential oil is enhanced. By adding the plant essential oil to influence the egg laying performance of the laying hens, the digestive absorption of the laying hens is improved, the egg laying rate of the laying hens is increased, and the egg laying efficiency of the laying hens is improved.

The invention discloses a river crab culture water treatment method. The treatment method comprises the following steps: cleaning a pond; fertilizing water and hanging ecological restoration bags; preventing and treating filamentous algae such as moss and the like; controlling blue-green algae outbreak; solving the problem of water quality index abnormity; and treating stress reaction and poisoning phenomena in low-pressure muggy weather and treating dark green water and red black water in the later period of culture. The river crab culture water treatment method has the beneficial effects that the treatment method is suitable for river crab breeding, physical, chemical, microorganism and biological new material products free of secondary pollution are used in the breeding process, secondary pollution is avoided, the problems of moss and blue-green algae outbreak and the like are effectively controlled, pesticide and antibiotic products are not needed in the breeding process, the breeding is easy, the quality of river crabs is good, and breeding benefits are high.

The invention provides bacillus velezensis and application thereof. The preservation number of the bacillus velezensis is CCTCC NO: M20211139, the bacillus velezensis is submitted and preserved in the China Center for Type Culture Collection on September 6, 2021, and the bacillus velezensis is classified and named as Ea 73 (Bacillus velezensis Ea 73). The bacillus velezensis is separated from Eupatorium adenophorum endophyte, has strong antibacterial activity and is stable in heredity. The bacillus velezensis is further added into a fermentation culture medium, the fermentation culture medium takes yeast extract powder as a carbon source, peptone as a nitrogen source and NaCl as inorganic salt, fermentation is performed at 27-28 DEG C for 48-52 hours, and the bacteriostatic activity of the fermented strain on staphylococcus aureus is further enhanced. Therefore, the strain and the enhanced strain are expected to be developed into natural antibiotic products.

The invention discloses a pig feed additive which belongs to the field of feed and relates to a feed additive. The pig feed additive comprises the following components in parts by weight: 10-25 parts of yeast extract, 10-18 parts of high-temperature resistance lactic acid bacteria, 5-10 parts of soybean peptide, 8-18 parts of ganoderma fruiting body, 5-15 parts of bran, 10-22 parts of cordyceps mycelia, 1-3 parts of fructose-oligosaccharide, 1-4 parts of raffinose, 1-3 parts of cellulase, 1-2 parts of protease, 1-3 parts of mixed amino acids and 0.5-2 parts of amino acid chelated copper. After being compounded, the pig feed additive has the advantages of having very good anti-diarrhea effect, effectively enhancing the immunity of piglets, reducing the application amount of antibiotic products and improving the growth quality of the piglets; and through application of the pig feed additive, the phenomena that the piglets have long hair in a nursing stage, and the growth and development of the pigments are hindered after the nursing stage are avoided.

The invention belongs to the field of animal husbandry, and particularly relates to a padding, feed, drinking water strains and bioisolation combined no-antibiotics ultivation method. The no-antibiotics cultivation method is characterized by comprising: (1) adding padding bacteria in the padding so as to manufacture a fermenting bed; (2) adding feed bacteria in the feed; (3) adding drinking water bacterium suspension in daily drinking water; and (4) planting greening trees and Chinese herbal medicine with a sterilizing effect to replace an isolating strip between each two adjacent colony houses. The no-antibiotics cultivation method remarkably improves a raising environment, increases cultivation income, reduces raising cost and cultivation risks, and provides a forceful guarantee for obtaining high-quality no-antibiotics products.

The invention discloses a feed for weaned piglets, and belongs to the technical field of feeds. The feed for weaned piglets is prepared from the following raw materials in parts by weight: 25-40 partsof corn, 15-20 parts of puffed corn kernels, 15-20 parts of soybean meal, 2-5 parts of whey powder, 0.04-0.05 part of a vitamin premix, 1-3 parts of a trace element premix, and 0.5-1.5 parts of fermented compound traditional Chinese medicine ingredients. The feed for weaned piglets disclosed by the invention is scientifically compounded so as to be suitable for gastrointestinal digestion characteristics of weaned piglets, and thus, the feed for weaned piglets is capable of reducing incidence of diarrhea, enhancing immunity of piglets, reducing usage of antibiotics in feeds and promoting growth of piglets.

The invention discloses feed additive compound essential oil for preventing diarrhea of pigeons. The essential oil is prepared from raw materials in parts by weight as follows: 5-50 parts of artemisia apiacea oil, 2-20 parts of sophora alopecuroides oil, 5-50 parts of thymol and 2000 parts of humic acid. The invention further provides a preparation method and an application of the essential oil. The essential oil as well as the preparation method and the application thereof has benefits as follows: according to the situation that users of pigeon farms using antibiotics during pigeon breeding are reduced day by day and under conditions that the antibiotics solve multiple disease problems for the pigeon farms in the past but problems of drug resistance to antibiotic products, drug residues and the like appear at the same time, scientific composition is provided according to the traditional Chinese medicine formula rule, the stable new preparation is prepared after essential oil is adsorbed by the humic acid, the essential oil has reasonable composition and is safe and effective, the raw materials are easy to obtain, the preparation technology is simple and easy to operate, and the production cost is low.

The invention discloses feed for pigs of 30-60kg. The feed comprises the following components in parts by weight: 600-700 parts of corn, 150-200 parts of soybean meal, 10-15 parts of cottonseed meal, 50-50 parts of DDGS (distillers dried grains with soluble) feed, 5-10 parts of grease, 8-12 parts of mountain flour, 8-10 parts of mineral elements, 4-6 parts of amino acid, 5-8 parts of vitamins and 0.3-0.5 part of an enzyme preparation. The mineral elements and the amino acid are combined, no hormone or antibiotic product is used, pigs in the fattening period can grow naturally, healthily and rapidly, the produced feed is in a half-cooked state and like paste, the weight of the pigs can be rapidly increased, the pig hair can be bright, and mineral elements essential for human bodies can be indirectly provided for human beings from the produced meat.

The invention belongs to the field of biochemistry, and in particular relates to a method for producing feed additives for piglets by using kelp leftover silage, which includes fermentation treatment, cultivating strains, preparing nutrient solution, inoculation and fermentation, etc., to make fermented kelp leftovers Fermented products. The additive of the present invention can increase the number of various probiotics and the activity of hydrolytic enzymes in livestock and poultry feed additives by adding kelp leftovers and compound microbial agents for scientific compounding and scientific fermentation, and increase nutrients such as total protein and total fat. The content of ingredients can improve the immunity of livestock and poultry animals, especially piglets, and the utilization rate of feed, and reduce the use of antibiotic products.

The invention provides a glycoside molecular derivative as well as a preparation method and application thereof, and belongs to the technical field of aminoglycoside antibiotics. The invention provides an etimicin derivative, and the etimicin derivative is a compound represented by the following formula and a pharmaceutically acceptable salt or prodrug thereof, wherein R1 represents a hydrogen atom, an ethyl group or an acetyl group, R2 represents a hydrogen atom, an ethyl group or an acetyl group, R3 represents a hydrogen atom, an ethyl group or an acetyl group, R4 represents a hydrogen atom,an ethyl group or an acetyl group, and R5 represents a hydrogen atom, an ethyl group or an acetyl group; wherein at least one of R1, R2, R3 is an ethyl group or an acetyl group; when R1 is an ethyl group, at least one of R2 and R3 is an ethyl group or an acetyl group; when R1 is an acetyl group, R2 and R3 can be hydrogen at the same time. The derivative can be used as a new aminoglycoside antibiotics product with low toxicity and resistance to drug-resistant bacteria, has good resistance to drug-resistant bacteria, and has a significant effect on resisting drug-resistant bacteria. The formulais shown in the description.

The invention provides a glycoside molecular derivative as well as a preparation method and application thereof, and belongs to the technical field of aminoglycoside antibiotics. The invention provides an etimicin derivative, and the etimicin derivative is a compound represented by the following formula and a pharmaceutically acceptable salt or prodrug thereof, wherein R1 represents a hydrogen atom, an ethyl group or an acetyl group, R2 represents a hydrogen atom, an ethyl group or an acetyl group, R3 represents a hydrogen atom, an ethyl group or an acetyl group, R4 represents a hydrogen atom,an ethyl group or an acetyl group, and R5 represents a hydrogen atom, an ethyl group or an acetyl group; wherein at least one of R1, R2, R3 is an ethyl group or an acetyl group; when R1 is an ethyl group, at least one of R2 and R3 is an ethyl group or an acetyl group; when R1 is an acetyl group, R2 and R3 can be hydrogen at the same time. The derivative can be used as a new aminoglycoside antibiotics product with low toxicity and resistance to drug-resistant bacteria, has good resistance to drug-resistant bacteria, and has a significant effect on resisting drug-resistant bacteria. The formulais shown in the description.

The invention relates to the technical field of relevant antibiotic products, and particularly provides a novel valnemulin premix product as well as a preparation technology and application thereof. The novel valnemulin premix product comprises valnemulin hydrochloride and many other auxiliary materials such as an anti-caking agent, an adsorbent, an adhesive and a diluent according to a certain ratio. The preparation technology of the novel valnemulin premix product comprises the following steps: 1), preparing materials; 2), crushing and sieving; 3), uniformly mixing; 4), pulping; 5), drying and granulating. The novel valnemulin premix product and pig feed are mixed or feeding, the weight of the novel valnemulin premix product is 0.2% that of the pig feed, and a mixture is continuously fedfor 7 days. The novel valnemulin premix product provided by the invention not only has high drug availability, good animal compliance and a significant therapeutic effect on sick pigs, but also is prepared by the simple preparation technology, is convenient to produce and use and small in side effects, and especially has a relatively good therapeutic effect of preventing and treating cough asthma, swine dysentery and hyperpyrexia syndromes of the sick pigs.

The invention discloses a penicillin antibiotic appearance evaluation method which is as follows: determining appearance standards of a certain penicillin antibiotic by use of spectrophotometric method, and comparing the determined appearance standards with the absorbance of other batches of solutions of the penicillin antibiotic to evaluate wether the appearance of the penicillin antibiotic product of the to-be tested batch is qualified. A penicillin antibiotic appearance naked eye observation method is replaced by the penicillin antibiotic appearance evaluation method, the appearance standard is quantifiable, easy to control, objective and accurate, and does not change with time, place, personnel changes. The penicillin antibiotic appearance evaluation method has the advantages of low cost, high precision and high efficiency in the popularization and application in industrial production.

The invention provides feed for laying hens and a preparation method thereof. The feed is prepared from the following components in parts by weight: 600-700 parts of corns, 110-150 parts of soybean meal, 40-50 parts of rapeseed meal, 50-60 parts of DDGS feed, 20-30 parts of corn protein powder, 5-10 parts of grease, 10-15 parts of mountain flour, 8-10 parts of mineral elements, 1-2 parts of amino acids, 5-8 parts of vitamins, 1-2 parts of microelements and 0.3-0.5 part of an enzyme preparation. According to the feed provided by the invention, the mineral elements and the amino acids are combined, and any hormone and any antibiotic product are not added; natural and healthy rapid growth of the laying hens is guaranteed, nutrients of the produced feed are balanced, and chicken feathers have bright color and luster; and produced chicken meat can indirectly supply needed mineral elements to human beings, and the laying amount is improved.