141results about How to "Reduce biodegradation" patented technology

The present invention features dendritic cell nodes that can be used to vaccinate subjects against pathogens and to modulate a subject's immune system to treat or prevent various diseases and conditions.

A demineralized bone putty composition comprises: (1) demineralized bone matrix (DBM); and (2) a lipid fraction selected from the group consisting of lecithin and a mixture of lecithin and triglycerides containing unsaturated fatty acids. The putty composition is moldable, biocompatible, slowly resorbable, and soluble in tissue fluids, and non-extrudable. The composition delivers a biologically active product to animals and humans that will enhance bone formation at sites where bone is lost, deficient, or present in suboptimal amounts. The composition can further comprise calcium, an antioxidant such as Vitamin E or Vitamin C, or a hydrophilic polymer such as methylcellulose or hydroxypropyl methylcellulose.

The present invention relates to a device consisting of cross-linked nanofibrillary fibrin supported on and rooted to a microporous nonwoven fabric consisting of a biocompatible synthetic polymer material. An active ingredient is advantageously dispersed in the fibrin layer. The fibrin layer does not have a haemostatic function, but is suitable for retaining the active ingredient and releasing it with controlled kinetics. The device forming the object of the invention, preferably in the form of patches, is useful for in vitro cell cultures or for treating tissues damaged by wounds or necrosis, such as cardiac walls bearing the sequelae of infarction, or a tissue damaged by a diabetic ulcer. The patch according to the invention can be manufactured by inducing the polymerisation of the fibrin, under suitable conditions, directly on the support layer, which is suitably impregnated with thrombin (at least in a superficial portion of its thickness), and which has been conveniently prepared by means of a spray phase-inversion technique.

A curable starch composition comprising a mixture of a starch and a curing agent having a functional group complementally reactive with at least one hydroxyl group contained in a starch molecule; and a modified starch having at least one substituent selected from the group consisting of a hydrocarbon group, acid group, blocked isocyanate group, isocyanate group, oxidative polymerizable group, radical polymerizable unsaturated group and amide group in a starch molecule.

One embodiment of the invention is demineralized bone putty composition comprises: (1) demineralized bone matrix (DBM); and (2) a lipid fraction selected from the group consisting of lecithin and a mixture of lecithin and triglycerides containing unsaturated fatty acids. The putty composition is moldable, biocompatible, slowly resorbable, insoluble in tissue fluids, and non-extrudable. The composition delivers a biologically active product to animals and humans that will enhance bone formation at sites where bone is lost, deficient, or present in suboptimal amounts. The composition can further comprise calcium, an antioxidant such as Vitamin E or Vitamin C, or a hydrophilic polymer such as methylcellulose, a methylcellulose derivative, carboxymethyl cellulose, or hydroxypropyl methylcellulose. A second embodiment of the invention is a demineralized bone paste composition comprising: (1) about 15% to about 75% of an emulsion carrier, such as an aqueous phase; and (2) a bone-material-containing phase comprising: (a) demineralized bone matrix (DBM); and (b) an emulsifier component that is compatible with lipids. This bone paste composition is moldable, biocompatible, slowly resorbable, miscible with bone graft materials, soluble or partially soluble in tissue fluids, and extrudable.

The invention relates to hyperbranched polyamino acid. The chemical composition is as follows: in the formula of (Lys-)a-(-Arg-)b-(-His-)c-(-X)d, Lys, Arg and His are respectively lysine, arginine and histidine, X is one of or a plurality of any amino acids except for the amino acids above, wherein a is not less than 0.2 and not more than 0.95, b is not less than 0 and not more than 0.8, c is not less than 0 and not more than 0.8, d is not less than 0 and not more than 0.3, and the sum of a, b, c and d is 1. The preparation method is as follows: uniformly mixing lysine or lysine salt with other amino acids or the amino acid salts contained in the hyperbranched polyamino acid to react for 2-64h at the temperature of 130-180 DEG C and then obtain yellow solid, and finally purifying the coarse product with a precipitation method to obtain the hyperbranched polyamino acid. The hyperbranched polyamino acid obtained in the invention can be used as nonviral gene carrier for the transduction of huamn or animal cell gene, and the hyperbranched polyamino acid nonviral gene carrier provided by the invention is reasonable in design, simple in preparation method, high in transfection efficiency, low cytotoxicity and favorable transduction efficiency in the presence of blood serum.

Methods of retarding the setting of a cement composition comprise including one or more secondary amines substituted with a carboxyl group or salts thereof (e.g., 3-hydroxy N,N′-iminodisuccinic acid) in the cement composition. The inclusion of such materials in cement compositions may be highly beneficial. In wellbores having BHCT's of less than or equal to about 250° F., the use of the secondary amine as the set retarder ensures that the thickening time of the cement composition is sufficient to allow the cement composition to be pumped to its desired downhole location. Further, the secondary amine may be used in combination with conventional set retarders to enhance the ability of those retarders to increase the thickening time of the cement composition at higher BHCT's, e.g., from about 250° F. to about 525° F.

A tree shelter includes a biodegradable fibrous mat coated with a degradable resin and adapted to be formed into a roll which can enclose at least the lower part of a plant. The mat is preferably non-woven and its structure is preferably impregnated with a second degradable resin which degrades at a different, preferably faster, rate to that of the first degradable resin under the same environmental conditions. Such a shelter has the advantage that once the first resin has substantially degraded over a predetermined time period to expose the mat to the weather, the second degradable resin commences a faster degradation to cause the mat to decompose rapidly into a loose fibrous state and ultimately form a beneficial mulch around the stem or trunk at the base of the plant.

A chewing gum composition includes at least one biodegradable gum base polymer, at least one sweetener and at least one flavor, the composition having low tack effected by a plurality of side chains attached to the backbone of at least one gum base polymer.

This invention relates to a biodegradable implant including magnesium, wherein the magnesium contains, as impurities, (i) manganese (Mn); and (ii) one selected from the group consisting of iron (Fe), nickel (Ni) and mixtures of iron (Fe) and nickel (Ni), wherein the impurities satisfy the following condition: 0< / (i)≦5, and an amount of the impurities is 1 part by weight or less but exceeding 0 parts by weight based on 100 parts by weight of the magnesium, and to a method of manufacturing the same.

Provided are: a biodegradable plastics composition which controls a biodegradation rate with a synergistic controlling effect on three components, adjusts a hydrolysis rate, and shows significantly improved weatherability; a molded article of the composition; and a method of controlling the biodegradation rate of a biodegradable plastics. The biodegradable plastics composition includes: a biodegradable plastics; and a carbodiimide compound, an ultraviolet ray absorbent, and an antioxidant to be blended as essential ingredients into the biodegradable plastics, and the molded article of the composition is also provided.

The invention relates to a method for processing phenol-containing waste water by anaerobic-aerobic coupling biofluidized bed, firstly making the waste water enter in a regulating pondage and then enter in a biofluidized bed containing macroporous suspended carriers for aeration and degrading the waste water by the anaerobic-aerobic coupling biotreatment; then draining the degraded waste water out of the biofluidized bed, placing still, draining upper-layer standard-reaching water, discharging a small part of the lower-layer water with deposited mud and returning the large part to the biofluidized bed for continuing taking part in the waste water processing process. And it implements coupling of anaerobic and aerobic biodegradations.

Cement compositions may comprise one or more secondary amines substituted with a carboxyl group or salts thereof (e.g., 3-hydroxy N,N′-iminodisuccinic acid) for retarding the setting of such compositions. The inclusion of such materials in cement compositions may be highly beneficial. In wellbores having BHCT's of less than or equal to about 250° F., the use of the secondary amine as the set retarder ensures that the thickening time of the cement composition is sufficient to allow the cement composition to be pumped to its desired downhole location. Further, the secondary amine may be used in combination with conventional set retarders to enhance the ability of those retarders to increase the thickening time of the cement composition at higher BHCT's, e.g., from about 250° F. to about 525° F.

The invention discloses a double controlled release film agent of implanted antineoplastic agent mitomycin and a manufacturing method; the invention relates to a medicinal controlled release film agent. The invention provides a double controlled release film agent of implanted antineoplastic agent mitomycin, which relates to a medicinal controlled release film agent with high enveloping ratio, long continuous release duration, small incidence of burst release, few toxic and side effects, high medicine concentration on tumor lesions and low recrudescence probability of tumor, and a manufacturing method. The film agent includes mitomycin, polymer, lecithin, chitosan and collagen. The mitomycin and the lecithin are dissolved, lyophilized in order to obtain a colloidal mixture; the polymer is dissolved in organic solvent in order to obtain a polymer solution; the polymer solution is then added in the colloidal mixture in order to obtain a reverse micelle; the reverse micelle is further added to a polyvinyl alcohol solution, and an O / W latex is obtained by emulsification; the latex is lyophilized in order to obtain carrier micro-spheres; the collagen is dissolved in the acid solution in order to obtain a collagen solution; the chitosan is dissolved in the acid solution in order to obtain a chitosan solution; the collagen solution and the chitosan solution are mixed in order to obtain a collagen-chitosan mixture solution; finally the carrier micro-spheres are dispersed in the collagen-chitosan mixture solution which is then poured in a mould and dried.

The invention relates to a medicament for fast preventing the malignant float grasses and the water algae and the application thereof, belonging to the pesticide formulation technical field, which is characterized in that the medicament comprises from 40% to 90% of a plant vinegar fluid, from 5% to 35% of an organic acid, and from 1% to 20% of pesticide addition agent, the plant vinegar fluid is either a bamboo vinegar fluid, a wooden vinegar fluid, and (or) grass vinegar fluid, the organic acid is one of or a mixture of more than one of a formic acid, an acetic acid, a propionic acid, a 2-methyl propionic acid, an ethyl acetic acid, a 4-hydroxy ethyl acetic acid, a pentanoic acid, a benzoic acid, a 2,6-hydroxy benzoic acid, a 3-hydroxy-4-methoxy benzoic acid or a 3-methoxy-4-hydroxy benzoic acid. The medicament has the advantages of fast destroying the chlorophyll, stopping the plant to do the photosynthesis, commonly killing the water algae in a half hour and the float grass in three hours by spraying, having low production cost, strong killing capability, wide adaptable temperature range and pH value range. The active component of the invention has the advantages of being the natural-occurring substance, no corrosion, nonirritant, safe use, and reliability, easy biodegradation, and no secondary pollution.

The invention provides a cabazitaxel albumin nanoparticle preparation and a preparation method thereof. The cabazitaxel albumin nanoparticle preparation comprises cabazitaxel, albumin and pharmaceutically necessary auxiliary materials and can be prepared with a high-pressure homogenization method, a film shearing method, a solvent evaporation method and the like. According to the cabazitaxel albumin nanoparticle preparation and the preparation method thereof, problems of the drug loading capacity and the stability of existing albumin nanoparticles are solved; a low-toxicity organic solvent is adopted, so that highly allergic reactions due to the fact that Tween-80 is adopted in a cabazitaxel injection liquid can be avoided; by the aid of the high permeability and the retention effect of the nanoparticle on tumors, more drugs can be targeted passively to be concentrated in tumor tissue, so that the anti-tumor effect is improved; the preparation method is simple and suitable for industrial mass production.

The invention discloses a preparation method and application of multifunctional chitosan composite sponge and relates to a preparation method and application of multifunctional oil-water separation sponge with effects of sterilization and separation of oil and water. Underwater super-hydrophobic CS-GO can be used to prepare underoil super-hydrophilic water absorption sponge with effects of sterilization and bioadhesion resistance. Chitosan is a bioenvironmental protection material, has good biocompatibility and biodegradability and is easy to recover again without causing any pollution. Chitosan and graphene oxide are compounded to form the composite sponge having a high specific surface area and the composite sponge is an efficient oil-water separation material having antibacterial activity and low toxicity. The preparation method can solve the problem of oil leakage pollution and bioadhesion in the oil-water separation process at present. The chitosan underoil super-hydrophilic sponge prepared by an ice template method has pore sizes of 20 to 300 microns, an adsorption capacity of 50 to 200g / g and separation efficiency of 99.5% or more in a test.

An apparatus for use in a liquid treatment process, and a method of use is described. The apparatus comprises an inlet configured to be connected to a source of liquid to be treated and an outlet for discharging liquid from the apparatus. At least one liquid treatment vessel or conduit is disposed between the inlet and the outlet, and is arranged to expose liquid in the vessel to ultraviolet radiation in an advanced oxidation process reaction. A source of ultraviolet radiation extending along the liquid treatment vessel or conduit, such that an annular flow volume is defined in the vessel or conduit around the source of ultraviolet radiation. A rotary device is disposed in the annular flow volume and a drive mechanism drives rotation of the rotary device. The rotary device is operable to induce cavitation in a liquid present in the annular flow volume.

The invention relates to carbonyl terminated hyperbranched polycarbonate capable of emitting bright fluorescence. Glycerol and diethyl carbonate are used as raw materials; a simple and controllable ester exchange condensation method is used for synthesizing the terminated hyperbranched polycarbonate; then, tert-Butyl acetoacetate is used for termination to obtain the hyperbranched polycarbonate. The synthesized hyperbranched polycarbonate does not contain pi keys such as benzene rings; the addition of fluorescent powder is not needed; the bright blue fluorescence can be given out; the characteristics of simple process, controllable process and low three-waste pollution are realized; in addition, the product stability is high; the toxicity is high; the biodegradability is high; the light intensity is high; the application range is wide.

The invention provides a cleaning liquid for semiconductor devices which is capable of removing deposits on a surface of an object to be cleaned including a photoresist, an antireflective film, an etching residue and an ashing residue at a low temperature in a short period of time with reduced environmental burdens and without causing corrosion of an interlayer dielectric film, a metal, a metal nitride, and an alloy in the object to be cleaned. The cleaning liquid for semiconductor devices according to the invention contains a reducing agent and a surfactant and has a pH of 10 to 14.

The invention identifies a narrow subset of Mycobacterium latency associated antigens and or epitopes that are capable of eliciting an immune response in vivo and in vitro in a mammal. The invention provides methods and compositions for detection and immunization against latent Mycobacterium infections. These compositions comprise those Mycobacterial latency antigens that are actually capable of eliciting an immune response in vivo, in mammals experiencing a latent Mycobacterium infection. More preferably the compositions comprise those antigens that are preferentially recognized by latently infected individuals and which antigens are not, or to a much lesser extent, recognized in individuals having an active Mycobacterium infection or in individuals having Mycobacterium induced symptoms or diseases, such as in patients infected with M. tuberculosis suffering from tuberculosis disease (TB).

Described herein are liquid crystalline elastomer compositions comprising aromatic epoxy units crosslinked with alkylene diacid units having alkylene segments containing at least one methylene unit, and / or aromatic epoxy units crosslinked with polyphenolic units, wherein the aromatic epoxy units and alkylene diacid units and / or polyphenolic units are in a molar ratio that results in the liquid crystalline elastomer composition exhibiting a glass transition temperature (Tg) and a thermal stability of the liquid crystalline phase (Tlc) that make them particularly suitable as shape memory materials and for use in methods of additive manufacturing. Methods for producing these compositions and their use in additive manufacturing processes are also described.

The invention relates to a method for casting a large investment pattern through rapid reversing and 3D printing. The method comprises the following steps that firstly, a reversed object is subjected to three-dimensional scanning through a scanner; secondly, rapid reverse three-dimensional modeling is conducted through software; thirdly, a three-dimensional model is subjected to data treatment through hierarchical processing software; fourthly, model manufacturing data obtained after data treatment are conveyed into a rapid forming machine, and rapid forming of a 3D printing model is conducted; fifthly, the 3D printing model serves as a lost foam casting to conduct investment pattern casting, and an investment pattern casting of the 3D printing model is obtained; and sixthly, the investment pattern casting is machined. Consumables used in a 3D printer are ordinary consumables PLA which are low-energy-consumption ecological environment-friendly materials most commonly used by the 3D printer, biodegradability is achieved, and bad influences on the human body and the environment are avoided. Due to the fact that the consumables PLA are made of corn, are renewable resources and have an extremely low shrinking percentage, it means that the consumables PLA are resistant to deformation even in a very large printing size.

The invention discloses a preparation method of a food-grade full-degradable high-temperature-resistant polylactic acid composite material, and belongs to the field of biodegradable high polymer materials. The composite material comprises, by weight, 100 parts of poly-l-lactic acid (PLLA), 1-10 parts of poly-d-lactic acid (PDLA) and 0.5-1 part of functional additives. Compared with traditional petroleum-based high polymer materials, the composite material has the advantages of being easy to degrade and renewable; compared with common polylactic acid, the composite material has excellent heat resistance. Thus, the polylactic acid composite material can be applied to high-temperature-resistant food packages.

The invention discloses a polylactic acid degradable composite material, comprising the following components in parts by weight: 40-70 parts of polylactic acid, 10-50 parts of filler, 2-10 parts of glycerinum and 0.2-2 parts of antioxygen. In order to reduce the manufacturing costs of the polylactic acid, starch with good biological degradability is added as the filler when in preparation, as the starch is abundant in resource, low in cost and fine in particle, so that the manufacturing costs of the polylactic acid can be reduced; however, the polylactic acid is not ideal enough in mechanical property due to the addition of the starch, in order to overcome the defect, nano-crystalline cellulose is added as an additive, as the nano-crystalline cellulose is strong in mechanical strength, the defect that the composite material is insufficient in mechanical strength due to the addition of the starch is made up, and thereby the composite strength still has high mechanical strength even lots of starch is filled.