The invention discloses a starch-novolac epoxy resin blended fully-degradable zip lock bag and a preparation method thereof. The starch-novolac epoxy resin blended fully-degradable zip lock bag is prepared from, by weight, 50-60 parts of novolac epoxy resin, 8-15 parts of calcium carbonate, 1-4 parts of nanometer titania, 10-20 parts of benzoin ethyl ether, 7-9 parts of nano-montmorillonite, 1.2-1.4 parts of tetrabutyl titanate, 12-14 parts of ramie sticks, 60-65 parts of corn starch, 2-3 parts of gelatin, 1-2 parts of magnesium stearate, 13-15 parts of acetyl tributyl citrate, 1-1.5 parts of 2,6-ditert-butyl-4-methylphenol, 4-6 parts of 3-hydroxybenzoic acid, 1-2 parts of laurinol sulfate and 4-6 parts of plant saponin. The product is produced according to a safe formula, and can be used for manufacturing food packaging bags and the like; during use, the product is high in strength, resistant to water and oil and durable, large-scale industrial production can be achieved, grasping is easy, popularization is convenient, the waste product can be automatically degraded under the effects of rich oxygen and microorganisms, carbon dioxide and water are finally generated, and the starch-novolac epoxy resin blended fully-degradable zip lock bag is ecological and environmentally friendly.