The invention discloses a synthesis method and application of Schwieterman stone, and belongs to the technical field of water treatment. The synthesis method of the Schwieterman stone comprises the following steps: (1) adding FeSO4.7H2O to an aqueous solution with a pH value of 2-7, performing even stirring, then adding H2O2, and then performing vibration treatment so as to form a precipitate; and(2) performing filtration and collection on the precipitate, performing washing with an acidic solution, and then conducting washing with deionized water, and performing vacuum freeze drying so as toobtain the solid catalyst Schwieterman stone. The yield of the Schwieterman stone prepared by using the method is high. When the prepared Schwieterman stone is used as a heterogeneous Fenton reactioniron-based material for Fenton-like oxidation reaction treatment on tetracycline, tetracycline in water can be removed effectively and efficiently, no secondary pollution to the environment is caused, the operation is simple, and the cost is low; and therefore a good application prospect is achieved in degradation of tetracycline pollutants in water.