31results about How to "Synthesis Yield Increased" patented technology

The invention relates to a trichlorosilane synthesis process and equipment. The invention aims at disclosing an improved trichlorosilane synthesis method and equipment, which have the advantages of high yield and low cost and providing the method and equipment for continuously recycling byproducts, such as chlorosilane and silicon tetrachloride produced in the trichlorosilane synthesis process. The method comprises the following steps of: respectively separating chlorosilane and silicon tetrachloride from synthetic product materials by using a rectified separation method, gasifying the chlorosilane and the silicon tetrachloride and then introducing into a synthesis reactor, and enabling the chlorosilane content and the silicon tetrachloride content to reach a dynamic balance in the operation process. Therefore, according to the invention, the synthesis output of the trichlorosilane is improved, consumption of raw materials, hydrogen, chlorine gas and the like is reduced, and thus the production cost is reduced.

The invention provides a method for synthesizing glutathione through fermentation, belonging to the field of production of glutathione. According to the method for synthesizing glutathione through fermentation, parameters such as concentration of a seed bacteria liquid, inoculum size and pH of a fermentation medium are optimized, the growth activity and fermentation activity of the yeast are maintained, the output of the glutathione is improved; and in fermentation, cysteine is added into the fermentation medium, the adding time and adding volume are optimized, so that the inhibition concentration of the glutathione can be improved, and the yield of the synthesized glutathione is further improved.

A single crystal CVD diamond material is disclosed, the material comprising a total nitrogen concentration of at least 3 ppm as measured by secondary ion mass spectrometry (SIMS); and a low optical birefringence such that in a sample of the single crystal CVD diamond material having an area of at least 1.3 mm * 1.3 mm, and measured using a pixel size of area in a range 1 * 1 [mu]m2 to 20 * 20 [mu]m2, a maximum value of deltan[average] does not exceed 1.5 * 10<-4>, where deltan[average] is an average value of a difference between refractive index for light polarised parallel to slow and fast axes averaged over the sample thickness. A method of making the material is also disclosed.

The invention relates to a squalene engineering strain, a squalene synthetic plasmid, a cell membrane space expansion plasmid and preparation methods. By constructing an engineering strain of a squalene synthetic pathway, developing a microbial cell factory and constructing a squalene synthetic unit of a gene related to membrane area expansion, the biosynthesis and industrial production process ofsqualene is promoted. According to the squalene engineering strain, the squalene synthetic plasmid and the preparation methods thereof, a green synthetic method for synthesizing the squalene in escherichia coli can reduce dependence on natural resources and overdevelopment. Moreover, the method is relatively low in cost, can realize large-scale squalene production, and has huge economic benefits.

The invention discloses a synthesis method and application of Schwieterman stone, and belongs to the technical field of water treatment. The synthesis method of the Schwieterman stone comprises the following steps: (1) adding FeSO4.7H2O to an aqueous solution with a pH value of 2-7, performing even stirring, then adding H2O2, and then performing vibration treatment so as to form a precipitate; and(2) performing filtration and collection on the precipitate, performing washing with an acidic solution, and then conducting washing with deionized water, and performing vacuum freeze drying so as toobtain the solid catalyst Schwieterman stone. The yield of the Schwieterman stone prepared by using the method is high. When the prepared Schwieterman stone is used as a heterogeneous Fenton reactioniron-based material for Fenton-like oxidation reaction treatment on tetracycline, tetracycline in water can be removed effectively and efficiently, no secondary pollution to the environment is caused, the operation is simple, and the cost is low; and therefore a good application prospect is achieved in degradation of tetracycline pollutants in water.

The invention discloses a method for synthesizing valtrate by utilizing ceratobasidium sp.AG-A. The method comprises the following steps of (1) inoculating a solid culture medium with ceratobasidium sp.AG-A mycelia for inverse culture, and after mycelium germination, selecting contamination free fresh mycelia in the periphery and inoculating a fresh solid culture medium with the fresh mycelia for continuous inverse culture to obtain mature mycelia, wherein the used ceratobasidium sp.AG-A is a collected strain in the China general microbiological culture collection center (CGMCC) and has a collection number of CGMCC No.9817; (2) inoculating a seed culture medium with the mature mycelia obtained in the step (1), and performing shaking culture to obtain a seed solution; and (3) inoculating a fermentation culture medium with the seed solution obtained in the step (2) for performing fermentation culture, adding citronellal to the fermentation culture medium in batches in the fermentation culture process, and then continuing to perform shaking fermentation culture to obtain a valtrate-containing culture solution. According to the method, the yield of synthesizing the valtrate by the ceratobasidium sp.AG-A can be effectively increased.

The invention discloses an 18F-labelled quinazolines irreversible EGFR (epidermal growth factor receptor) positive electron tracer agent, as well as a preparation method and application thereof. The 18F-labelled quinazolines irreversible EGFR positive electron tracer agent has a chemical structure represented by the formula II. The synthesized 18F-labelled small-molecular irreversible EGFR positive electron tracer agent has a clinical value for diagnosing and monitoring a treating effect and particularly plays an important role in pushing individual-based treatment. Furthermore, the invention further provides a one-step method for synthesizing the 18F-labelled small-molecular irreversible EGFR positive electron tracer agent. The method has the characteristics of multiple purposes, high yield, high efficiency, short synthesis time, low cost and the like and can meet a requirement on large-scale production.

The invention provides a method for synthesizing 5-hydroxy beta-indolyl alanine by taking beta-indolyl alanine as a substrate and application of the 5-hydroxy beta-indolyl alanine. The 5-hydroxyl beta-indolyl alanine high-producing strain provided by the invention is used for a method for synthesizing 5-hydroxyl beta-indolyl alanine by a biological method by taking beta-indolyl alanine as a substrate, and the synthesis yield of the 5-hydroxyl beta-indolyl alanine is high. Through construction of a BH4 regeneration system and excavation of a new BH4 regeneration enzyme, the regeneration capacity of an engineering strain BH4 is enhanced, and especially the yield of biosynthesized 5-hydroxyl beta-indolyl alanine is remarkably increased under the simultaneous action of a double BH4 regeneration system.

The invention relates to a method for synthesizing diamonds, in particular to a method for synthesizing diamonds by electroplating at normal pressure. In the method, transition group metals and transition group metal alloys are added with carbons and put in a pot for melting, and under the normal pressure, the temperature of between 1000 and 1600 DEG C, the voltage of between 2 and 36V and the electric current of between 300A and 1800A, the mixture in the pot undergoes the electroplating for 1 to 800 minutes, and after powering-off, the cathode is taken out and undergoes electrolytic partially or acid alkali treatment to remove impurities, and finally diamonds are obtained. The method of the invention can accurate control such technical parameters of synthesis as temperature, voltage and current, etc. with low equipment investment, little energy consumption and simple process, greatly improve the quality of diamonds and resolve the problems of expensive equipment, unstable quality, low conversion rate, hard collection and high synthesis cost existing in the synthesis of diamonds made by prior static pressure methods, explosion methods, gas phase deposition synthesis methods, etc. In the invention, surface of electroplating liquid are covered by graphite powders or the pot is protected by vacuum or inert gases, so the diamonds with higher grade or jewel grade can be obtained.

The invention discloses an 18F-labeled quinazoline type EGFR (epidermal growth factor receptor) positron tracer, as well as a preparation method and an application thereof and belongs to the field of chemical synthesis. The 18F-labeled quinazoline type EGFR positron tracer disclosed by the invention has a chemical structure as shown in a formula II. The synthesized 18F-labeled small molecular EGFR type positron tracer has clinical value of diagnosis and monitoring of treatment curative effect and particularly plays an important role in promoting personalized treatment. In addition, the invention further provides the method for full-automatic synthesis of the 18F-labeled quinazoline type EGFR positron tracer by one step, the method has the characteristics of multiple purposes, large yield, high efficiency, short synthesis time, low cost and the like, and the requirements of large-scale production can be further met.

The invention relates to a cyclodextrin glucosyltransferase with improved product specificity and a preparation method, belonging to the fields of genetic engineering and enzyme engineering. The present invention provides three cyclodextrin glucosyltransferase mutants L174P, L174Y and L174D with high genistein glycosylation efficiency. Compared with wild type cyclodextrin glucosyltransferase, they use maltodextrin as sugar When using the base donor to produce glycosylated genistein, the synthesis yield of long-chain glycosylated genistein increased by 0.7, 1.2 and 1.8 times, respectively, which is more conducive to the industrial production of glycosylated genistein.

The invention provides streptomyces toxytricini for high yield of lipstatin, wherein the streptomyces toxytricini can high-efficiency utilize grease, and has a performance of high yield of lipstatin. On the other hand, the invention further provides an optimized streptomyces toxytricini fermentation medium.

The invention discloses an 18F labeled quinazoline class EGFR (Epidermal Growth Factor Receptor) positron tracer agent and a preparation method and application thereof and belongs to the field of chemical synthesis. The 18F labeled quinazoline class EGFR positron tracer agent has a chemical structure as shown in a formula II. The synthesized 18F labeled micro-molecular EGFR class positron tracer agent has the clinic values of diagnosis and therapeutic effect monitoring and particularly plays an important role in promoting personalized treatment. Besides, the invention further provides a one-step method, namely a method for fully-automatically synthesizing the 18F labeled quinazoline class EGFR positron tracer agent. The method has the characteristics of multiple purposes, high yield, high efficiency, short synthesis time, low cost and the like and can meet the requirements of large-scale production. The formula II is shown below.

The invention relates to a trichlorosilane synthesis process and equipment. The invention aims at disclosing an improved trichlorosilane synthesis method and equipment, which have the advantages of high yield and low cost and providing the method and equipment for continuously recycling byproducts, such as chlorosilane and silicon tetrachloride produced in the trichlorosilane synthesis process. The method comprises the following steps of: respectively separating chlorosilane and silicon tetrachloride from synthetic product materials by using a rectified separation method, gasifying the chlorosilane and the silicon tetrachloride and then introducing into a synthesis reactor, and enabling the chlorosilane content and the silicon tetrachloride content to reach a dynamic balance in the operation process. Therefore, according to the invention, the synthesis output of the trichlorosilane is improved, consumption of raw materials, hydrogen, chlorine gas and the like is reduced, and thus the production cost is reduced.

The invention relates to a recycling method of naturally volatile ammonia gas. The method comprises the following steps that in a finished product ammonium hydroxide storage process, part of the ammonia gas diffuses into the air from ammonium hydroxide, pressure of the ammonia-containing air above ammonium hydroxide tanks builds up to generate positive pressure, and under the action of differential pressure, the ammonia-containing air flows in a direction of an atmospheric spraying absorption tower and enters the spraying absorption tower from the tower bottom of the spraying absorption tower;the ammonia-containing air goes up from an inlet of the tower bottom, and meanwhile, soft water is sprayed from the tower top to make the ammonia-containing air and the soft water subjected to countercurrent contact; in a countercurrent contact process, ammonia gas in the ammonia-containing air is completely dissolved in water and falls to the tower bottom along with liquid, so that purified airgoes up continuously to the tower top for emptying; after absorbing the ammonia gas, the soft water on the tower bottom is fed back to the tower top again through a circulating pump, and added again for purifying ammonia-containing air. According to the recycling method of the naturally volatile ammonia gas, the ammonia gas which diffuses above the finished product ammonium hydroxide tanks is effectively collected to form dilute waste ammonium hydroxide liquid, in-organization diffusion is prevented, and the dilute waste ammonium hydroxide liquid is used for carbonizing the soft water of a system, so that resources are reasonably used.