68 results about "P-Toluic acid" patented technology

The invention discloses a mesosulfuron-methyl synthetic method. The mesosulfuron-methyl synthetic method is characterized in that mesosulfuron-methyl is prepared from raw materials such as paratoluic acid by adopting the seven steps of chlorosulfonation-ammonolysis, oxidation, dehydration, reduction, alcoholysis, methyl sulfone chloride acylation and condensation. The mesosulfuron-methyl synthetic method provided by the invention has the advantages of being low in cost of the raw materials, easy in availability of the raw materials, simple in operation and mild in conditions, having low requirements on equipment, high yield and strong practicability and being suitable for industrial production.

The invention relates to a selective hydrogenation catalyst of aromatic aldehydes for refining of terephthalic acid. The selective hydrogenation catalyst is mainly used for solving the problems that the hydrogenation of 4-carboxy-benzaldehyde (called as 4-CBA for short) in the prior art mainly generates p-toluic acid (referred to as P-TA), the amount of hydrogen consumption is great and the operation cost is high. The selective hydrogenation catalyst adopts activated carbon as a carrier and is supported with one or more metals of palladium, ruthenium, nickel, zinc and copper, and the like; therefore, the technical proposal can better solve the problems and can be used in the industrial production for hydrogenation refining of the terephthalic acid.

The invention discloses a method and equipment for preparing terephthalic acid by the air oxidation of p-xylene. The method is as follows: in the reaction system in which an oxidation reactor is connected with a crystallization separator in series, p-xylene containing metalloporphyrin catalyst or the mixing catalyst of metalloporphyrin and metal salt, and air, oxygen-diluted air, rich oxygen air or air with carbon dioxide are fed in the oxidation reactor and stay for 70 minutes to 180 minutes in the reactor at the temperature of 140 DEG C to 200 DEG C. The oxidation reaction mixture enters into a crystallizer for crystallization by overflow or pumping. The p-xylene, p-toluic acid and p-methyl benzyl alcohol obtained by separation is pumped into the oxidation reactor to be mixed with the p-xylene containing metalloporphyrin catalyst for secondary oxidation, and the fine terephthalic acid is obtained by purification after crystallization. The invention has the advantages that the p-xylene is directly oxidized into terephthalic acid by air, the energy consumption is low, the production efficiency is high, and the conversion rate of p-xylene and the yield of terephthalic acid can achieve more than 95 percent.

The invention relates to a polyester fiber with a low melting point and a method for preparing the polyester fiber. The polyester fiber with the low melting point is of a skin-core structure, skin layers are made of polyester with a low melting point, and core layers are made of PET (polyethylene terephthalate); the polyester with the low melting point comprises terephthalic acid chain segments, isophthalic acid chain segments, ethylene glycol chain segments, diethylene glycol chain segments and molecular weight regulator end-capping groups; corresponding molecular weight regulators of the molecular weight regulator end-capping groups particularly comprise benzoic acid, p-toluic acid or ethylbenzoic acid, or methyl ester or ethyl ester corresponding to the benzoic acid, the p-toluic acid or the ethylbenzoic acid, or saturated fatty acid or methyl ester or ethyl ester corresponding to the saturated fatty acid; the content of acetaldehyde in the polyester fiber with the low melting point is lower than 0.5 ppm. The method includes steps of polymerizing the polyester with the low melting point and carrying out composite spinning on skin and cores; carrying out back spinning by the aid of drafting-washing processes; carrying out oil-bath drafting by the aid of added sodium sulfite; carrying out crimping, cutting-off and drying to obtain the polyester fiber with the low melting point. The polyester fiber with the low melting point and the method have the advantages that the polyester fiber prepared by the aid of the method has the low melting point and is low in acetaldehyde content.

The invention provides a treatment and reuse method of purified terephthalic acid refining wastewater. In the method, neutralization and solid-liquid separation is adopted as pretreatment before film treatment, and a double-film method technology combining ultrafiltration and two-level reverse osmosis is used to conduct film treatment, therefore, suspended matters in wastewater are efficiently removed, the removal rate of metal ions, such as cobalt, manganese and the like, as well as organic substances, such as 4-carboxybenzaldehyde, benzoic acid, p-toluic acid and the like, which are soluble in water, are above 99 percent, the effluent electric conductivity is less than 5muS/cm, and the water using requirement of a production system refining unit is achieved. Because the efficient pretreatment before film treatment technology is adopted, the process of the film treatment can stably run for a long term with reliable treatment effect and low running cost.

The present invention relates to a process for making terephthalic acid by reacting a starting material and oxygen in the presence of a heterogeneous catalyst and p-xylene as solvent to produce a solution of terephthalic acid (TPA). The starting material is p-xylene, p-toluic acid, 4 carboxybenzaldehyde, or a mixture of any two or more thereof. No solid TPA is formed during the reaction in contrast to previous manufacturing methods that utilize acidic solvents and precipitate TPA as it forms. By avoiding the direct precipitation of TPA during formation, the present methods avoid many shortcomings of the conventional manufacturing methods used to produce TPA. In particular, the present methods do not require additional purification steps to remove reaction byproducts; film grade TPA can be obtained directly from starting material in a one-step process.

Topically applicable cosmetic/dermatological photoprotective compositions contain at least one dibenzoylmethane UV-screening agent, and, as a photostabilizer therefor, at least one arylalkyl benzoate compound of formula (I) or (II) below:

with the proviso that: (i) the subject compositions are characteristically devoid of any octyl methoxycinnamate; and (ii) same are other than a solution of butyl methoxydibenzoylmethane in 2-phenylethyl benzoate, 2-phenylethyl o-toluate, 2-phenylethyl p-toluate or in a 2-phenylethyl o-toluate/2-phenylethyl p-toluate (1/1) mixture.

The present invention relates to the manufacture of alkyl p-toluates from an alkyl p-toluic acid ester and a mono-functional, branched, linear or cyclic medium chain length alkyl alcohol, and their use as a plasticizer in polymers. Additionally, the present invention relates to articles and materials comprising such alkyl p-toluates.

The invention relates to a preparation method of imatinib. The preparation method provided by the invention has simple steps and can be used for preparing imatinib in two steps. The preparation method comprises the following steps: A, reacting p-Toluic acid serving as a raw material with halogenated phthalate esters or acyl chlorides in an organic solvent under catalytic action of alkali at -30 DEG C to 100 DEG C to obtain mixed anhydride; B, condensing the mixed anhydride and N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine under the action of alkali to obtain amide, and then further reacting amide with N-methyl piperazine to obtain imatinib. The method disclosed by the invention has the advantages that the reaction steps are simplified and only two reaction steps are needed; and the raw material is easily available, the operation is simple, the cost is low, the product yield is high and the product quality is good; therefore, the method is suitable for large-scale production.

The invention discloses a method for measuring content of dimethylbenzene oxidation products by using an HPLC external standard method. According to the method, a high performance reversed-phase liquid chromatograph instrument is adopted, a C18 silica gel chromatographic column is taken as a separation column, an ultraviolet visible absorption detector is adopted, methanol and an acid aqueous solution are taken as mobile phases, phthalate, isophthalic acid and terephthalic acid are taken as standard samples, a concentration-peak area standard curve of a target component is drawn by using the external standard method so as to obtain a linear regression equation, and contents of the phthalate, isophthalic acid and terephthalic acid are calculated by using the regression equation. Through adoption of the method, three main products with similar polarity and four byproducts including 3-formylbenzoic acid, benzoic acid, paratoluic acid and p-tolualdehyde can be separated effectively, and the method takes short time in analysis, is easy and feasible, and is convenient and reliable.

The invention discloses a carbon nano-polytetrafluoroethylene valve seal ring filled with ceramic sol. The seal ring is prepared from, by weight, 100 parts of polytetrafluoroethylene, 5-8 parts of carbon nanotubes, 8-10 parts of phenol, 8-10 parts of p-toluic acid, 1-2 parts of bentonite, 1-2 parts of barium strontium titanate, 5-8 parts of diphenyl ether, 1-3 parts of butyl titanate, 20-25 parts of sodium hypochlorite with the concentration of 60%-70%, 20-25 parts of EDTA, 40-50 parts of ammonia water, 80-100 parts of absolute ethyl alcohol, 3-4 parts of deionized water, 10-20 parts of glacial acetic acid, 30-40 parts of ethylene glycol monomethyl ether, 8-10 parts of a dehydrating agent acetic anhydride, 3-4 parts of polyvinyl alcohol, 3-5 parts of barium sulfate, 1-2 parts of molybdenum disulfide, 1-3 parts of a silane coupling agent kh550, 9-10 parts of ammonium chloride, 30-35 parts of urea and 30-35 parts of water. The seal ring is resistant to aging and abrasion and long in service life.

The invention provides non-naturally occurring microbial organisms having a (2-hydroxy-3-methyl-4-oxobutoxy) phosphonate (2H3M40P) pathway, p-toluate pathway, and/or terephthalate pathway. The invention additionally provides methods of using such organisms to produce 2H3M40P, p-toluate or terephthalate. Also provided herein are processes for isolating bio-based aromatic carboxylic acid, in particular, p-toluic acid or terephthalic acid, from a culture medium, wherein the processes involve contacting the culture medium with sufficient carbon dioxide (C02) to lower the pH of the culture medium to produce a precipitate comprised of the aromatic carboxylic acid.