Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

288results about How to "Reduced pH" patented technology

Manufacturing process for the production of peptides grown in insect cell lines

The present invention provides a manufacturing method for the production of peptides that are grown in insect cell lines. The peptides are grown in insect cell cultures that are infected with baculovirus particles in a culture supplemented with a lipid mixture. The peptides are then isolated from the insect cell culture using a method that employs a tangential flow filtration cascade. The isolated peptides are glycopeptides having an insect specific glycosylation pattern. The glycopeptides may then be conjugated to a modifying group via linkage through a glycosyl linking group interposed between and covalently attached to the peptide and the modifying group. The conjugates are formed from glycosylated peptides by the action of a glycosyltransferase.
Owner:NOVO NORDISK AS

Degradable therapeutic delivery device

A biodegradable biodelivery device is disclosed. The biodelivery device is formed from a polymer comprising the reaction product of a polyol and a polyacid. When exposed to water, the polymer degrades through hydrolysis. Of particular advantage, the polymer can be formed so as to be elastic and flexible. In one embodiment, the polymer is formed into a vaginal insert. As the polymer degrades, the polymer releases acid to a vaginal environment for decreasing the pH of the environment.
Owner:KIMBERLY-CLARK WORLDWIDE INC

Process for removal and recovery of nutrients from digested manure or other organic wastes

A process for removal and recovery of nutrients and recycling of water from digested manure or other organic wastes. A first step involves separating waste from an anaerobic digester into digested liquids, digested solids, and biogas. A second step involves precipitating solids from the digested liquids. A third step involves stripping ammonia from the digested liquids. A fourth step involves injecting an exhaust stream of carbon dioxide drawn from the co-generator into the digested liquids to reduce the pH and raise the temperature of the digested liquid. A fifth step involves recycling the digested liquids back to the anaerobic digester for use in diluting in coming solid wastes. A sixth step involves passing the excess ammonia stripped from the digested liquid through the digested solids to recover nitrogen through aborption with the resultant digested solids being usable as a biofertilizer with a high nitrogen content. A seventh step involves capturing the biogas for use in a co-generation system.
Owner:HIGHMARK RENEWABLES RES PARTNERSHIP

Rapid Acting and Long Acting Insulin Combination Formulations

A combined rapid acting-long acting insulin formulation has been developed wherein the pH of the rapid acting insulin is decreased so that the long acting glargine remains soluble when they are mixed together. In the preferred embodiment, this injectable basal bolus insulin is administered before breakfast, provides adequate bolus insulin levels to cover the meal, does not produce hypoglycemia after the meal and provides adequate basal insulin for 24 hours. Lunch and dinner can be covered by two bolus injections of a fast acting, or a rapid acting or a very rapid acting insulin. As a result, a patient using intensive insulin therapy should only inject three, rather than four, times a day. Experiments have been performed to demonstrate the importance of the addition of specific acids to hexameric insulin to enhance speed and amount of absorption and preserve bioactivity following dissociation into the monomeric form by addition of a chelator such as EDTA. As shown by the examples, the preferred acids are aspartic, glutamic and citric acid. These are added in addition to a chelator, preferably ethylenediaminetetraacetic acid (EDTA). The results show that the citric acid formulation was more effective at dropping the blood glucose rapidly than the identical rapid acting formulation prepared with HCl in swine. Charge masking by the polyacid appears to be responsible for rapid insulin absorption. EDTA was not effective when used with adipic acid, oxalic acid or HCl at hastening the absorption of insulin. These results confirm the results seen in clinical subjects and patients with diabetes treated with the rapid acting insulin in combination with citric acid and EDTA.
Owner:ELI LILLY & CO

Method and Apparatus for Decontamination of Fluid with One or More High Purity Electrodes

The invention relates to methods and apparatuses for the decontamination of fluid, particularly the removal of heavy metals and / or arsenic and / or their compounds from water, by means of electrocoagulation followed by adsorption, wherein the water to be purified subjected to electrodes of different polarities. The invention can include means for control of the pH of the fluid. The invention can also include control systems that allow self-cleaning of electrodes, self-cleaning of filters, and automatic monitoring of maintenance conditions.
Owner:KLOSE GISELHER +1

Warming and nonirritating lubricant compositions and method of comparing irritation

This invention relates to substantially anhydrous warming, non-toxic and nonirritating lubricating compositions containing polyhydric alcohols and an insulating agent as well as gel and jelly compositions related thereto. The invention also relates to methods of using such compositions for lubrication, administration of active ingredients and for preventing or treating dysmenorrhea.
Owner:RECKITT BENCKISER HEALTH LTD +1
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products