The invention discloses a water vapor-sensitive color change ink, which is prepared from a water-sensitive salt, a pH indicator, a binder and a solvent. The invention also discloses a humidity-sensitive anti-counterfeit label, comprising an indicating layer, a base layer, a stripping layer and a first adhesive layer which can be attached to a product, wherein the indicating layer is formed on the base layer, the adhesive layer is arranged on the first adhesive layer, and the stripping layer is arranged on the first adhesive layer; the indicating layer is formed by ink printing, and the ink is prepared from the water-sensitive salt, the pH indicator, the binder and the solvent. The invention can not only solve the problem that the humidity indicating ink is not friendly to a human body, but also can solve the problem that the humidity indicating ink is hard to print, and can not only solve the problem that anti-counterfeiting color change ink can only be screen-printed, but also can solve the problem that the anti-counterfeiting color change ink depends on liquid water.