457 results about "Dimethacrylate ester" patented technology

The present invention provides interpenetrating polymer network hydrogels that have high oxygen permeability, strength, water content, and resistance to protein adsorption. The hydrogels include two interpenetrating polymer networks. The first polymer network is based on a hydrophilic telechelic macromonomer. The second polymer network is based on a hydrophilic monomer. The hydrophilic monomer is polymerized and cross-linked to form the second polymer network in the presence of the first polymer network. The telechelic macromonomer preferably has a molecular weight of between about 575 Da and about 20,000 Da. Mixtures of molecular weights may also be used. In a preferred embodiment, the hydrophilic telechelic macromonomer is PEG-diacrylate or PEG-dimethacrylate and the hydrophilic monomer is an acrylic-based monomer. The material is designed to serve as a contact lens.

The invention discloses a preparation method for a porous monolithic column immobilized enzyme micro-reactor. The porous monolithic column immobilized enzyme micro-reactor is prepared according to the preparation method as follows: firstly, a poly (GMA-co-EDMA) monolithic column is prepared; and then the poly (GMA-co-EDMA) monolithic column is modified by cysteamine and gold nanoparticles so as to obtain a porous polymer monolithic column, wherein, the gold nanoparticles are immobilized on the surface of the porous polymer monolithic column. Enzyme is immobilized to the hole surfaces of the porous monolithic column modified by the gold nanoparticles by utilizing the action of Au-NH2 bond, and then the porous monolithic column immobilized enzyme micro-reactor can be obtained. The preparation method has the advantages as follows: the preparation method is simple; enzyme immobilization reaction conditions are moderate; the permeability of the enzyme micro-reactor is good; large immobilized enzyme quantity can be achieved; the activity, the service life and the stability of enzyme are high in comparison with free solution enzymolysis, and enzyme can be used repeatedly.

The present invention belongs to the technical field of bioengineering, and relates to a method for purifying sulfanilamide by using a molecularly imprinted polymer of a sulfanilamide drug. The method comprises the following steps: (1) mixing and dissolving template molecules of a sulfanilamide drug mixture, a functional monomer of methacrylic acid and a cross-linking agent of ethylene glycol dimethacrylate in a pore forming agent (a ratio of methanol to acetonitrile is 2:3); adding an initiator, and sealing; (2) crushing the synthesized polymer, removing fine particles, removing the template molecules through extraction; (3) drying the template molecule-removed polymer overnight at a temperature of 60 DEG C to obtain the molecularly imprinted polymer of the sulfanilamide; (4) filling the molecularly imprinted polymer into a solid phase extraction column tube; (5) activating the solid phase extraction column, adding an animal tissue extraction solution or a water sample, wherein the animal tissue extraction solution is dissolved in 40% methanol; then leaching the solid phase extraction column to elute and purify the sulfanilamide. The method provided by the present invention has advantages of high selectivity, high specificity and adverse environment resistance, and has broad application potential.

The invention relates to a preparation method of a triazine phytocide molecular imprinting solid phase extracting material. The method comprises the following steps of: 1. dissolving butyltripolycyanamide, alpha-methacrylic acid, glycol di(methacrylic acid)ester and azodiisobutyronitrile into trichloromethane and uniformly mixing to obtain a suspending phase I; 2. dissolving polyvinyl alcohol 1788 into water to obtain a suspending phase II; and 3. stirring and reacting the suspending phase I with the suspending phase II and drying in vacuum to obtain the triazine phytocide molecular imprinting solid phase extracting material. In the invention, by adopting a substituted molecular template, the imprinting effect is ensured and the problem of template seepage is solved; the optimized use condition is more convenient for solid phase extraction and ensures favorable impurity removing function and favorable repeatability; the matrix effect is remarkably weakened; and the triazine phytocide molecular imprinting solid phase extracting material is better than the traditional main stream solid phase extracting product, not only can ensure the detecting accuracy but also can improve the detecting sensitivity and effectively protect a chromatographic column.

The present invention provides materials that have high glucose and oxygen permeability, strength, water content, and resistance to protein adsorption. The materials include an interpenetrating polymer network (IPN) hydrogel that is coated with biomolecules. The IPN hydrogels include two interpenetrating polymer networks. The first polymer network is based on a hydrophilic telechelic macromonomer. The second polymer network is based on a hydrophilic monomer. The hydrophilic monomer is polymerized and cross-linked to form the second polymer network in the presence of the first polymer network. In a preferred embodiment, the hydrophilic telechelic macromonomer is PEG-diacrylate or PEG-dimethacrylate and the hydrophilic monomer is an acrylic-based monomer. Any biomolecules may be linked to the IPN hydrogels, but are preferably biomolecules that support the growth of cornea-derived cells. The material is designed to serve as a corneal prosthesis.

The invention provides a dibutyl phthalate molecularly imprinted polymer (DBP-MIP) solid phase extraction column and a preparation method and application method thereof, belonging to the technical field of analytical chemistry. The DBP-MIP is prepared by dissolving a template molecule DBP, a functional monomer methacrylic acid and a crosslinking agent ethylene glycol dimethacrylate into a porogen chloroform or acetonitrile, adding an initiator azobisisobutyronitrile, filling nitrogen to remove oxygen, carrying out initiated polymerization at 55-75 DEG C, and grinding, sieving and washing a polymer after completing reaction. The preparation method is characterized by weighing a certain amount of polymer and filling the polymer into a polypropylene column to prepare the solid phase extraction column. The prepared MIP solid phase extraction column can highly selectively separate and enrich DBP in samples such as environment, food, chemical products and the like and effectively remove matrix interference, and has great application values and market prospects.

The invention discloses a melamine molecular imprinted solid phase extraction cartridge and a preparation method and application thereof. The melamine molecular imprinted solid phase extraction cartridge is characterized in that a glass cartridge provided with a quartz sand sieve plate on the internal bottom is filled with melamine molecular imprinted polymer particles. Melamine, methacrylic acid, ethylene glycol dimethacrylate are mixed and dispersed in the aqueous solution of methanol or ethanol to prepare the melamine molecular imprinted polymer particles which are filled in the glass cartridge and obtain the melamine molecular imprinted solid phase extraction cartridge. The invention achieves the high-efficiency separation, enrichment and purification of melamine in the milk products, compared with the related techniques, such as prior solvent extraction, C18 solid phase extraction and ion exchange solid phase extraction, the melamine molecular imprinted solid phase extraction cartridge has high enrichment and purification efficiency and low cost, can be repeatedly used and is expected to be the necessary means for the residue pre-treatment of melamine in the milk products.