99 results about "Alkalinizing agent" patented technology

The present invention is related to an oral dosage form comprising an effective amount of an alkalizing agent and an azithromycin multiparticulate wherein said multiparticulate comprises azithromycin, a glyceride which comprises glyceryl monobehenate, glyceryl dibehenate, glyceryl tribehenate, or a mixture thereof and a poloxamer. Typically, the oral dosage form includes any suitable oral dosing means such as a powder for oral suspension, a unit dose packet or sachet, a tablet or a capsule.

A composition useful for the oxidation dyeing of human keratinous fibers and in particular hair containing, in a cosmetically acceptable medium based on water and at a basic pH, at least one oxidation dye and an alkalinizing agent containing at least one alkali metal, alkaline-earth metal or ammonium metasilicate and at least one alkanolamine, and the dyeing method using this composition.

A composition and method are described for sanitizing or otherwise treating a material such as a non-living surface, living tissue, soil or atmosphere which may be contaminated by a toxin, chemical warfare agent, insect, prion, microorganism or other infectious agent. The composition generally includes an aqueous composition mixture that includes: (a) lower alkanol; (b) an alkalinating agent, and (c) a fatty acid salt and / or ester. The components are present in an effective amount to sanitize (or treat) a material (or modifying a chemical contained thereon) to which the composition is applied. Also described are methods of making the composition.

An oral dosage form comprising azithromycin and an effective amount of an alkalizing agent. Preferably, said oral dosage form comprises an effective amount of an alkalizing agent and an azithromycin multiparticulate wherein said multiparticulate comprises azithromycin, a mixture of glyceryl monobehenate, glyceryl dibehenate and glyceryl tribehenate, and a poloxamer. Typically, the oral dosage form includes any suitable oral dosing means such as a powder for oral suspension, a unit dose packet or sachet, a tablet or a capsule. Additionally disclosed is an oral suspension comprising azithromycin, an effective amount of an alkalizing agent and a vehicle. Preferably, the azithromycin is in multiparticulate form wherein said multiparticulate comprises azithromycin, a mixture of glyceryl monobehenate, glyceryl dibehenate and glyceryl tribehenate, and a poloxamer. Also disclosed is a method for reducing gastrointestinal side effects, associated with administering azithromycin to a mammal, comprising contiguously administering azithromycin and an effective amount of alkalizing agent to said mammal wherein the frequency of gastrointestinal side effects is lower than that experienced by administering an equal dose of azithromycin without said alkalizing agent. Further disclosed is a method of treating a bacterial or protozoal infection in a mammal in need thereof comprising contiguously administering to said mammal a single dose of an oral dosage form wherein said oral dosage form comprises azithromycin and an effective amount of an alkalizing agent. Additionally disclosed are azithromycin multiparticulates comprising azithromycin, a surfactant; and a pharmaceutically acceptable carrier.

The invention discloses a preparation method of a medicament solid preparation. The method comprises the following steps of: dissolving active ingredients of a water-insoluble and / or water-poorly-soluble acid medicament into an alkaline solution containing a basifier to obtain a medicament-containing alkaline liquid; and uniformly mixing auxiliary materials with the medicament-containing alkaline liquid, and performing wet process pelletizing. The invention further discloses a medicament solid preparation prepared with the method. Due to the adoption of the preparation method disclosed by the invention, the defects of severe pollution, large loss and severe potential safety hazard caused by mechanical smashing treatment are overcome, and the effects of reducing the particle sizes of the active ingredients of the water-insoluble and / or water-poorly-soluble acid medicament in a pelletizing process is achieved. The method is easy and convenient to operate, is practicable, has high safety coefficient, and is easily applied to industrial production. The solid preparation prepared with the method has excellent dissolving characteristic, stability and content uniformity.

The present invention relates to a system to highlight the hair. The system comprises a device (10) and a composition (50). Device (10) comprises a first portion movably joined to a second portion. Composition (50) comprises a percentage of hydrogen peroxide and a percentage of an alkalizer by weight of said composition (50). The weight percentages of hydrogen peroxide and of an alkalizer are defined by equation (I): X+1.5Y≧15 (I) wherein X is the percentage by weight of hydrogen peroxide by weight of the composition (50) and wherein Y is the percentage by weight of an alkalizer by weight of the composition (50). Said composition (50) comprises at least 2% of hydrogen peroxide by weight of said composition (50) and said alkalizer is an inorganic salt selected from the group consisting of sodium silicate, sodium metasilicate, potassium hydrogen carbonate, ammonium carbonate, ammonium hydrogen carbonate and sodium hydrogen carbonate and mixtures thereof. Said composition (50) allows to perform highlighting when applied with the device (10) as described herein.

The present application concerns an aqueous metalworking composition comprising in a concentrate or after dilution of a concentrate with water in a diluent: 0.002 to 40 % by weight of component (a) which is a lubricity agent comprising at least one water-insoluble compound (a) having at least one hydrophobic aliphatic chain and at least one polar group and having a water solubility at 20 DEG C of less than 0.1 g / liter; 0.002 to 40 % by weight of component (b)comprising at least one water-soluble corrosion inhibiting compound(b) having a water-solubility at 20 DEG C of more than 0.1g / liter; 0.002 to 45 % by weight of at least one emulsifying and dispersing agent(c)which contains at least one emulsifying and / or dispersing compound (c) which is water-soluble, water-miscible or water-dispersable and which is selected from the group consisting of non-ionic, anionic and zwitterionic surfactants; 0.002to 30 % by weight of an alkalinity agent (d) containing at least one alkaline water-soluble compound (d) selected from the group consisting of hydroxides and carbonates; and 0.004 to 99 % by weight of a transport component(e)containing predominantly water. Further on, the present application concerns a method of use of such aqueous metalworking composition as a coolant, as a lubricant, etc., and concerns further on a method to prepare an aqueous metalworking composition and a metalworking process.

Dry, enteric, film-coating compositions and aqueous dispersions containing the same are disclosed. When applied to orally-ingestible substrates such as oral solid dosage forms, the film coatings are capable of preventing the substrates from disintegrating in media with pH values from about 1 to about 4.5 or higher values. One preferred film-coating composition contains a micronized intermediate comprised of an acrylic resin and talc. Advantageously and surprisingly, the preferred film-coating composition does not contain an alkalizing agent.

A biopolymer thinning process is provided comprising the steps of (a) mixing a biopolymer substrate with a thinning agent and an alkalizing agent; and (b) drying the mixture of step (a), wherein the thinning agent consists of one or more hypochlorites; and step (a) is carried out at a neutral to alkaline pH and does not involve any artificial heating.