364results about How to "Strong growth inhibitory effect" patented technology

The invention relates to a method for preparing a biologic herbicide-containing fertilizer from biogas slurry by using biogas slurry as a main raw material. The method is characterized by comprising the following steps of: screening biogas slurry with a sieve of 120 meshes, and adding a compound microorganism bactericide prepared from antagonistic bacilli to prepare the biologic herbicide-containing fertilizer. In the biologic herbicide-containing fertilizer, the number of antagonistic bacilli reaches 5-6*10<7> CFU / ml. The antagonistic bacilli comprise geobacilli, bacillus amyloliquefaciens and bacillus subtilis.

The invention discloses a bacillus amyloliquefacien and a preparation method and application thereof. According to the bacillus amyloliquefacien and the preparation method and the application thereof, the culture collection number of the bacillus amyloliquefaciens H6 is CCTCC No: M2013249; the bacillus amyloliquefaciens has obvious growth inhibition effect for gram-positive bacteria and gram-negative bacteria, strong degradation ability for starch, albumen, and cellulose, strong environment tolerance, and excellent effect for preventing diarrhea and promoting growing, and can not produce adverse effect with large doses of feeding; and the rear condition is simple, the cost is low, and the development and application prospect is excellent.

The invention discloses an anthraquinone compound having the formula shown in the following formula (I) or formula (II). The anthraquinone compound with a novel structure is a natural product obtainedby fermenting and purifying rice by actinomycetes, has obvious anti-tumor activity, especially has significant proliferation inhibition for human prostate cancer cell line PC3 cells and human colon cancer cell line SW620 cells, and can be used for developing anti-tumor drugs. (The formulas are shown in the description.).

treating method for hair growth inhibition, which comprises administering (A) the extract of a plant of the family Juniperus or a malt. In addition, the present invention relates to a dermatologic composition for external use, which comprises (B) an elastase inhibitor or neutral endopeptidase inhibitor, and the above-described component (A) and / or (C) at least one proteolytic enzyme selected from the group consisting of papain, trypsin, chymotrypsin, pepsin, bromelain, ficin and pancreatin.

The invention provides an ursolic acid derivative, which is N-[3beta-acetoxy-ursa-12- alkene-28-acyl]-aminoethylenediamine-folic acid. A natural product ursolic acid is structurally transformed to obtain N-[3beta-acetoxy-ursa-12- alkene-28-acyl]-aminoethylenediamine-folic acid (I), N-[3beta-acetoxy-ursa-12-alkene-28-acyl]-aminoethylenediamine (III) and N-[3beta-acetoxy-ursa-12- alkene-28-acyl]-aminoethylenediamine (IV). The in vitro cell proliferation inhibition test shows that the proliferation inhibition effect of the compounds I, III and IV on tested tumor cell lines HepG2, of BGC823, A-375, Hela and the like is superior to that of the ursolic acid, and the toxic effect of the compounds I, III and IV on human embryonic lung fibroblasts (HELF) is lower than that of the ursolic acid. The in vitro anti-tumor effect of the compound III is the best, and the compound I has certain targeting.

The invention belongs to the battery material field, in particular to a nanometer Zn @ C negative electrode material for a secondary zinc-based battery and a preparation method thereof. C in the negative electrode material is a nano carbon material, the thickness of the negative electrode material is 50-100 [mu]m and a Zn grain size is 20-80 nm; the preparation method comprises the following steps: adding nano-carbon material into nano-zinc plating solution for electroplating, then washing with water and drying to obtain the nano-Zn @ C negative electrode material; DC, high frequency forward pulse current or high frequency bi-directional pulse current can be used for electroplating; The nanometer zinc plating solution comprises zinc sulfate, boric acid and grain refiner, the pH value is 1to 3, and the solvent is water. The negative electrode material prepared by the invention has good adhesion, no zinc shedding after 20 times of 90 DEG bending tests, strong dendritic growth inhibitionability, excellent specific capacity, cycle life, coulomb efficiency and magnification performance, and is proved to be good in effect by magnification test and suitable for large-scale industrial production.

The invention relates to flavones separated and purified from shepherd's purse. The method comprises the following steps: ethanol ultrasonic extraction, solvent extraction, silica gel column chromatography eluting separation, resin column adsorption, silica gel column chromatography eluting separation, vacuum concentration, vacuum drying and the like. The name of the separated flavones is 2-(3,4-dimethoxyphenyl)-5-(hydroxymethyl-7-O-beta-D-glucosyl-4H-chromene-4-one. The raw material, which is the medicinal and edible shepherd's purse, has abundant sources and is cheap and accessible. The prepared 5-hydroxymethyl new flavones have novel structure, have obvious effect of inhibiting tumor cell proliferation, and can be used as a cell proliferation inhibitor or antitumor agent for antitumor research. The flavones have favorable development and utilization values, and lay foundation for research and development of clinical drugs for preventing and treating tumors in future.

The invention relates to Cu-Eu exotic-metal-substituted arsenotungstate which has a chemical formula as follows: Na2K3.5Eu0.5[Eu(H2O)7][As2W19Cu2O67(H2O)3].22H2O. A compound is prepared by reacting EuCl3, CuCl2.2H2O, NaCl and an arsenotungstate precursor-K14[As2W19O67(H2O)] in an aqueous solution. A preparation method is simple, easy to operate and relatively low in cost. Tests discover that the compound has a remarkable inhibition effect on the growth of human hepatocarcinoma cells HepG2 and human colonic cancer cells HCT-116 and can be used for preparing drugs for resisting cancers, especially liver cancers and colonic cancers, and research results provide an experimental basis for application of the compound to an aspect of drug activity.

The invention discloses a production method for sophorolipid with a hair growing effect. According to the production method, reprocessed oils extracted from animals or plants serve as raw materials, and a hydrolysis method of the raw material oils, a fermentation method of sophorolipid and an extraction and separation method are included. The sophorolipid has better hair growing and hair losing resisting effects when applied to cosmetic production, and is natural and nontoxic, capable of promoting cell proliferation and enhancing cell metabolism and beneficial to hair growth.

The invention relates to an alpha, beta-unsaturated ketone compound containing a 1,2,4-oxadiazoles heterocycle, the structure of which is as shown in general formula 5, wherein R1 is hydrogen, methyl or chlorine; R2 is methyl, chlorine or bromine; R3 is methyl or ethyl; R4 is para-trifluoromethyl, ortho-methyl or para-nitro; and R5 is hydrogen or methyl. The invention also provides a preparation method of the compound and application thereof. The half-growth inhibitory concentration of the compound on HL-60 cells is less than or equal to 2.0 mu M, and the activity is obviously improved, thus the compound can be used for preparing antileukemie medicaments.