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35results about How to "Reduce drug use" patented technology
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Feed additive for preventing fatty liver of largemouth bass
InactiveCN104664170ARepair damaged liver cellsReduce drug useFood processingAnimal feeding stuffCarthamusHerb
The invention provides a feed additive for preventing a fatty liver of largemouth bass. The feed additive is prepared from the following raw materials in parts by weight: 15-22 parts of astragalus membranaceus, 13-20 parts of salviae miltiorrhizae, 4-8 parts of pericarpium citri reticulatae, 4-8 parts of fingered citron, 4-8 parts of citron, 7-12 parts of hawthorn, 3-6 parts of radix glycyrrhizae preparata, 5-8 parts of flos carthami, 4-6 parts of christina loosestrife herb, 4-6 parts of rheum officinale, 4-6 parts of herba artemisiae scopariae, 2-4 parts of curcuma aromatic, 4-8 parts of vitamin C, 3-5 parts of vitamin E, 3-6 parts of methionine and 1-3 parts of choline. The feed additive provided by the invention is capable of effectively preventing a fatty liver disease of the largemouth bass, so that frequent fatty liver phenomenon in a fish body when an artificial compound feed is used instead of fresh-frozen products in largemouth bass culture is solved; and an effective solving way is provided for healthy sustainable farming of the largemouth bass.
Owner:GUANGDONG HAID GROUP
Beverage capable of lowering and preventing high blood sugar
The beverage capable of lowering blood sugar and preventing hyperglycemia contains birch down extract, kudzu vine root isoflavone, ginsenoside and other natural functional medicine-food components. The beverage can regulate and lower blood sugar, promote the recovery of diabetics, lower the medicine dosage of diabetics and prevent hyperglycemia.
Owner:武斌
Acne treating compound Chinese medicine prepn
InactiveCN101019948AAntibacterial and antipruriticInhibition of keratinizationDermatological disorderMolluscs material medical ingredientsMentholSide effect
The acne treating compound Chinese medicine preparation is prepared with ginseng, pearl powder, honeysuckle, dahurian angelica root, almond and other eight kinds of Chinese medicinal materials. The preparation process includes washing the medicine materials, crushing, decocting, filtering, centrifuging to obtain supernatant, concentrating, adding pearl powder, menthol, far infrared nanometer ceramic powder, etc, high temperature sterilizing, adding glycerin and ethanol. It has functions of resisting bacteria, relieving itch, reducing oil secretion, etc. and thus obvious acne treating effect and no side effect.
Owner:许炎军
Gastrodia elata forage for chickens and preparation method thereof
InactiveCN103493995AEnhance physical fitnessReduce drug useAnimal feeding stuffHorticultureRice flour
The invention discloses gastrodia elata forage for chickens and a preparation method thereof. The gastrodia elata forage is prepared from 480-500 weight parts of corn, 180-200 weight parts of soybean meal, 30-40 weight parts of pumpkin, 20-30 weight parts of rice bran, 20-30 weight parts of wheat bran, 10-15 weight parts of black sesame powder, 10-15 weight parts of black glutinous rice flour, 15-20 weight parts of black corn powder, 10-15 weight parts of black peanut powder, 50-70 weight parts of silkworm chrysalis powder, 25-30 weight parts of alfalfa, 5-10 weight parts of ginkgo leaf, 5-10 weight parts of gastrodia elata, 2-4 weight parts of ginseng, 8-11 weight parts of soybean paste and 4-5 weight parts of a phagostimulant. Through use of the Chinese herbal medicines such as gastrodia elata, the gastrodia elata forage improves chicken physique and reduces medicine use amounts. Through use of black sesame, palatability is improved, forage intake of chickens is improved and growth is accelerated. Through use of the gastrodia elata forage, a laying peak period of laying hens is effectively prolonged.
Owner:安徽省瑞森生物科技有限责任公司
Method for ecologically breeding pelteobagrus fulvidraco
InactiveCN106577403AImprove fish immunityReduce drug useClimate change adaptationAgricultural fishingSparid FishWater environment
The invention discloses a method for ecologically breeding pelteobagrus fulvidraco. The method comprises the following steps: constructing an ecological floating bed, culturing in a planting barrel, stocking pelteobagrus fulvidraco fingerling, arranging the ecological floating bed, dynamically adjusting the floating bed, performing breeding management and the like. According to the method, arrangement and adjustment of the ecological floating bed are beneficial to maintaining the water temperature of a pond in a reasonable range and keeping the pond water to be clear, and an appropriate breeding water environment is produced to bred pelteobagrus fulvidraco. The pelteobagrus fulvidraco ingesting below the planted herba houttuyniae and the like is beneficial to improving the its immunity, and usage of medicines can be reduced. Besides fish catch, water spinach, herba houttuyniae and other economic crops can be harvested.
Owner:FRESHWATER FISHERIES RES CENT OF CHINESE ACAD OF FISHERY SCI
Method for extracting effective compositions from composition of fructus ligustri lucidi and radix astragali through supercritical extraction process and products thereof
InactiveCN104083447ANo residueReduce drug useOrganic active ingredientsImmunological disordersTreatment effectEvaporation
The invention discloses a method for extracting effective compositions from a composition of fructus ligustri lucidi and radix astragali through a supercritical extraction process and products thereof. The method comprises: crushing radix astragali and fructus ligustri lucidi and performing low-temperature drying, performing first extraction on radix astragali and fructus ligustri lucidi respectively or on a mixture of radix astragali and fructus ligustri lucidi by using supercritical carbon dioxide as an extracting agent, performing reduced-pressure evaporation and vacuum drying on the extracting liquid, so as to obtain a polyose-composition extracting product; performing secondary supercritical extraction on the first extraction residue, so as to obtain a flavonoid-composition extracting product; performing third supercritical extraction on the second extraction residue, so as to obtain a saponin-composition extracting product; and performing forth supercritical extraction on the thrid extraction residue, so as to obtain a terpene-composition extracting product The extraction method is capable of improving the extraction rate and the purity of the effective compositions in the composition of fructus ligustri lucidi and radix astragali, thereby reducing the dose of an astragalus membranaceus-ligustrum healthy-qi-reinforcing preparation and enabling the astragalus membranaceus-ligustrum healthy-qi-reinforcing preparation to have relatively good treatment effect.
Owner:GUIZHOU XINBANG PHARMACEUTICAL CO LTD
High-efficiency scanning spraying method of whole plants of Allium fistulosum
The invention discloses a high-efficiency scanning and spraying method of whole plants of Allium fistulosum. The scanning spraying method is achieved through combination of a conventional power sprayer with a medicine switch, a spray main switch, a split-flow tee, double handles, double spray rods, double spray heads and other special spraying components, the spraying positions of the left-and-right two sets of spray heads can be changed, and the directions of nozzle holes of the spray heads can also be changed through rotation; and during spraying operation, the relative positions of the left-and-right two sets of spray heads are kept static, and are consistent with the advance direction of an operator, the advance trajectory of the spray heads is a straight line during the scanning spraying operation, and the static scanning spraying width is larger than the width of crop targets, so that efficient and precise scanning spraying is performed on three different agronomic-trait crops which include Allium fistulosum crops, tiled-type crops and low-cluster-type canopy plants. When the method is compared with commonly-used knapsack manual sprayers or knapsack electric sprayers, the work efficiency can be increased by 3 times or above, water can be saved by 60%, chemicals can be saved by 65%, and the control effect of pests and diseases can be improved by 8-33%; and moreover, the novel scanning spraying mode for the three types of crops which include Allium fistulosum is developed, and the level of the spraying technology and spraying devices of the three types of crops can be improved.
Owner:福州市农业科学研究所 +1
Drug balloon catheter and surface treatment method of drug balloon
PendingCN114259606AHigh saturationIncrease the transmission areaBalloon catheterMedical devicesMicrospherePharmaceutical drug
The invention discloses a medicine balloon catheter and a surface treatment method of a medicine balloon. The medicine balloon catheter comprises a catheter base, a catheter body, a balloon body, a pressure opening, a medicine coating and a protective coating. Comprising the following steps: S1, firstly preparing microspheres, weighing a certain amount of a carrier and a medicine, and dissolving in a solvent a to obtain a solution A; s2, preparing PVA or cellulose or a mixture aqueous solution thereof with the concentration of 2%-15% to obtain a solution B; the balloon has the advantages that the saturation degree and the conveying area of the drug coating on the balloon are effectively improved, the drug can be coated on the blood vessel wall through single expansion, the operation difficulty is effectively reduced, the operation time is shortened, meanwhile, the bioavailability is higher, the lasting tissue drug treatment concentration can be kept, and the application prospect is wide. And moreover, the loss of the medicine coating in the conveying process can be effectively prevented, and finally the purposes of improving the medicine utilization rate, reducing the medicine dosage and reducing the side effect of the medicine on the human body as much as possible are achieved.
Owner:珠海市立通生物科技有限公司
Application of composition of ginsenoside C-K and lamotrigine in preparation of anti-epilepsy medicines
InactiveCN105963311ALower doseGood effectNervous disorderHeterocyclic compound active ingredientsAntiepileptic drugLamotrigine
The invention relates to novel medicines and application, and particularly provides application of a composition of ginsenoside C-K and lamotrigine in preparation of anti-epilepsy medicines. Animal experiments prove that the composition of ginsenoside C-K and lamotrigine can be used for remarkably prolonging the incubation period of epilepsy, reducing the attack strength of epilepsy, shortening the duration of epilepsy and reducing the weight loss after attack, and indicate that the composition of ginsenoside C-K and lamotrigine can be used for relieving or controlling attack of epilepsy and inhibiting occurrence and development of epilepsy, and adverse medicine response caused by lamotrigine can be alleviated by reducing the dosage of lamotrigine.
Owner:欧阳冬生 +1
Component-compatible traditional Chinese medicine for preventing and treating Alzheimer disease
InactiveCN108514582AReduce toxic effectsReduce drug useNervous disorderPlant ingredientsLigusticum chuanxiongGinsenoside
The invention discloses a component-compatible traditional Chinese medicine for preventing and treating an Alzheimer disease. Raw material for extracts of traditional Chinese medicine effective components contains the following ingredients: ginseng or total saponins of panax ginseng; coptis chinensis or total alkaloids from coptis chinensis; and ligusticum wallichii or ligusticum wallichii alcoholextract. Compared with the original traditional Chinese medicine formula (Prepared polygonum multiflorum, ginseng, acorus gramineus, coptis chinensis and ligusticum wallichii), indexes of new compatibility of traditional Chinese medicine components in an animal behavior aspect and pathology change are better than those of compatibility of the original formula, and the new compatibility of the traditional Chinese medicine components has the same effects with the original formula in the aspect of controlling inflammation level; meanwhile, toxic effect and dosage of the original formula are reduced, the effective ingredients including ginsenoside, berberine and ligustrazine of the component-compatible traditional Chinese medicine are also clear and can achieve pharmacological effects by virtue of a blood brain barrier, the traditional Chinese medicine component compatibility accords with traditional Chinese medicine theory, the material basis for efficacy is clear, and characteristics ofthe modern traditional Chinese medicinal preparation are reflected, and therefore, the component-compatible traditional Chinese medicine disclosed by the invention is an ideal medicine for preventingand treating the Alzheimer disease.
Owner:XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI
Dry powder inhalant with lung cancer-resistant activity
ActiveCN106420677AReduce drug useIncrease concentrationOrganic active ingredientsPowder deliveryReproductive systemLung cancer
The invention discloses a dry powder inhalant with lung cancer-resistant activity. The dry powder inhalant with the lung cancer-resistant activity comprises yuanhuacine and a lactose carrier, wherein the lactose carrier is prepared from rough lactose with the diameter being more than 110 microns and fine lactose with the diameter being 4 to 11 microns. According to the dry powder inhalant with the lung cancer-resistant activity, the yuanhuacine and the inhalable lactose are innovatively mixed to prepare the dry powder inhalant for treating lung cancer, the medicine is directly given to a target part locally and accurately, the concentration of the medicine at the target point is increased, the toxic and side effects of other tissues are reduced and the curative effect is improved. An optimal prescription process is screened out by using a new-generation medicinal impactor to simulate a pulmonary administration method, so that more medicines are settled in the lung, an in-situ administration effect is achieved, and the lung tissue targeting aim is fulfilled. The dry powder inhalant with the lung cancer-resistant activity can obviously increase the concentration of the medicines in the lung tissue, improve the curative effect of treating the lung cancer, reduce the distribution of the medicines in the heart, liver, spleen, kidney, brain and reproductive system and reduce the toxicity on other tissues.
Owner:NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
Flos lonicerae-herba artemisiae-fructus gardeniae extract and preparation method and application thereof
InactiveCN112451574AImprove pharmacological activityReduce drug useAntiviralsPlant ingredientsGardenia gummiferaChemistry
The invention belongs to the technical field of medicine, and particularly relates to a flos lonicerae-herba artemisiae-fructus gardeniae extract, a preparation method thereof and application of the flos lonicerae-herba artemisiae-fructus gardeniae extract to preparation of anti-Coxsackievirus A6 medicines. Antiviral experiment results show that the petroleum ether part, the ethyl acetate part andthe n-butyl alcohol part of the flos lonicerae-herba artemisiae-fructus gardeniae alcohol extract have high anti-CV-A6 activity; Fractions H and J of the petroleum ether part of the flos lonicerae-herba artemisiae-fructus gardeniae alcohol extract have high anti-CV-A6 activity; the fraction E of the ethyl acetate part of the flos lonicerae-herba artemisiae-fructus gardeniae alcohol extract has good anti-CV-A6 activity. and 30% alcohol and 60% alcohol elution products of the n-butyl alcohol part of the flos lonicerae-herba artemisiae-fructus gardeniae alcohol extract have high anti-Coxsackievirus A6 activity.
Owner:SHANDONG FIRST MEDICAL UNIV & SHANDONG ACADEMY OF MEDICAL SCI
Noise collecting system device for sewage plant blower
ActiveCN103821725AReduce energy lossReduce drug useRotary/oscillating piston pump componentsLiquid fuel engine componentsCollection systemHigh energy
The invention discloses a noise collecting system device for a sewage plant blower. The noise collecting system device is composed of three parts, namely a sound collecting zone, a sound guiding zone and a sound dividing zone, wherein the sound collecting zone comprises a reflecting shield, a sound collecting shield, a shrinking section, a sound binding section which is used during noise binding of a plurality of blowers, and the like; the sound guiding zone is composed of a straight line sound guiding pipe and an elbow; the sound dividing zone comprises a sound dividing shield, a sound dividing pipe, a sound dividing hole and the like; moreover, a noise reduction layer is arranged outside the whole collecting system. The noise collecting system device can fully collect and guide the blower noise, can reduce noise energy loss as much as possible, can facilitate full utilization of high energy of noise, and has a wide development space and market prospect.
Owner:SOUTHWEAT UNIV OF SCI & TECH
Medicine composition for treating chronic nephritis and preparation method thereof
ActiveCN102813700AHigh drug loadingReduce drug useUrinary disorderCapsule deliveryDrugPatent medicine
The invention provides a medicine composition for treating chronic nephritis. The medicine composition is a pellet prepared from the following raw materials and accessory in parts by weight: Chinese medicine herb raw materials: 4,166 parts of lespedeza virgata, 750 parts of radix scutellariae, 1,000 parts of folium pyrrosiae and 1,000 parts of radix astragali; and accessory: 39-98 parts of filler, wherein the filler is one of starch, soluble starch and dextrin or the mixture of more than two thereof. The invention also provides a preparation method of the medicine composition. In the invention, according to the physicochemical characteristics of the raw material extract of 'Shenyansiwei tablets', the raw materials are prepared into pellets and then encapsulated, thus relatively large drug loading capacity is ensured, and the problem that the medicine can not be prepared into hard capsules on the premise of reducing the dose of the patent medicine of the original dosage form is solved; and meanwhile, in the preparation process of pellets, by observing the pill forming method, the type of adhesive and wetting agent and the drying method, the dosage of the accessory and the drying time are further reduced, the production cost is effectively saved, and industrial production is possible.
Owner:韩兵
Health-care feed improving compactness of grass carp scales in breeding period and a preparation method thereof
InactiveCN106173520AReduce morbidityReduce drug useFood processingClimate change adaptationCorn starchSOYBEAN SEED OIL
The invention relates to a health-care feed for improving the compactness of grass carp in breeding period and preparation method thereof, and belongs to the technical field of fish feed production. The feed comprises the following raw materials: 5-25 parts of soybean meal, 8-30 parts of rapeseed meal, 3-10 parts of fermented rapeseed meal, 5-15 parts of cottonseed meal, 3-10 parts of domestic DDGS, 3-10 parts of imported DDGS, 5-15 parts of rice bran, 5-15 parts of flour, 5-12 parts of corn starch, 2-5 parts of soybean oil, 1-3 parts of potassium dihydrogen phosphate, 1-2.5 parts of bentonite, 0.05-0.3 part of lysine hydrochloride at 98.5%, 0.05-0.1 part of choline chloride, 0.3-0.8 part of vitamin premix, 0.5-1.5 parts of mineral premixes, 0.01-0.05 part of an antioxidant and 0.1-0.15 part of a mildew preventive. The products can enable the immune function of the grass carps to be the best, improve the disease resistance of the grass carps, avoid the looseness and falling of the grass carp scales when the grass carps are centrally caught in the market, at the same time does not improve the feed costs, and thus can enhance the comprehensive culture benefits of farmers.
Owner:昆明通威饲料有限公司
Green Chinese onion multi-line scanning and spraying component
The invention discloses a green Chinese onion multi-line scanning and spraying component. A power sprayer is matched with a special spraying component, scanning and spraying are implemented by multi-group stereoscopic clamp spraying of the left side and the right side of a green Chinese onion line, the positions of two groups (or more than two groups) of spray nozzles are kept still during spraying operation and consistent with the advancing direction of an operator, and the advancing track of the spray nozzles for scanning and spraying operation is overlapped with the center line of the straight or curved green Chinese onion line. Spray rods can adopt thickened and lengthened structures, the number of vertical rods, vertical rod tees, left spray nozzles and right spray nozzles can be matched with that of green Chinese onion lines needing simultaneous scanning, the total length of the spray rods reaches 20-30 meters, and the spray rods are fixed to the back of a suspended drag sprayingmachine in a suspended manner. According to the scanning and spraying component, water and pesticides are saved, pesticide droplet spraying uniformity and target hitting rate are improved, environmental pollution and waste caused by the pesticides are reduced, and the component can be applied to hilly farmlands in southern hilly regions and can also be applied to northern flat plain farmlands.
Owner:福州枫蕊生态科技有限公司
Mixed culture method for fishes and macrobrachium nipponense
InactiveCN107711609ANo breeding pollutionReduce drug useFood processingClimate change adaptationDrugDisease
The invention provides a mixed culture method for fishes and macrobrachium nipponense. The method comprises the following steps: firstly disinfecting a macrobrachium nipponense pond, cultivating macrobrachium nipponense larvae through mating of male and female macrobrachium nipponense, throwing the macrobrachium nipponense larvae from the middle ten days of the July to the middle ten days of the August, throwing fry from the September to the October, and performing feeding and culture. According to the invention, the method takes full advantage of idle production resources, does not need to increase professional equipment, has no culture pollution, employs industrialized management personnel and normative culture technical standards, applies a biological agent to control water quality, reduces the use amount of drugs, makes the macrobrachium nipponense meet pollution-free and healthy requirements, and improves product quality value. In addition, the high-quality macrobrachium nipponense larvae obtained after hybridization can exert heterosis, and has obvious improvement in aspects such as improvement of a growth speed and disease and stress resistant ability and delaying of sexualmaturity than macrobrachium nipponense larvae obtained by cultivation of traditional local macrobrachium nipponense parents.
Owner:柯桂林
Method for establishing zebrafish senile dementia model and application
ActiveCN108935231AReduce drug useAlzheimer's disease symptomsClimate change adaptationAccessory food factorsD-GlucoseSenile dementia
The invention particularly relates to a method for establishing a zebrafish senile dementia model and application. A glucose culture solution and an okada acid culture solution are included,the glucose culture solution and the okada acid culture solution are alternately used for culturing zebrafishes, and a single culture time of the glucose culture solution orthe okada acid culture solution is 22-26 hours. The method disclosedis the first methodwhich alternately cultures the zebrafishes with a specific concentration of the glucose culture solution and the okada acid culture solution, zebrafish senile dementia-like symptoms can be quickly and effectively caused, thereby greatly reducing the dosage of okada acid, and experimental resources are saved.
Owner:BIOLOGY INST OF SHANDONG ACAD OF SCI
Bactericidal composition containing picoxystrobin and metrafenone
InactiveCN107980779AReduce drug useReduce manufacturing costBiocideFungicidesTriticella flavaSuspending Agents
The invention relates to a bactericidal composition containing picoxystrobin and metrafenone. A weight ratio of active ingredients, namely picoxystrobin and metrafenone, is preferably (1-40):(40-1), further perferably (1-20):(20-1); and the bactericidal composition comprises 1-85% by mass of the active ingredients and the balance of auxiliary ingredients allowed to be used and accepted in pesticides. A dosage form of the bactericidal composition is a water dispersible granule, wettable powder, a suspending agent, aqueous emulsion, microemulsion and the like, and the bactericidal composition ismainly used for preventing and controlling wheat scab and wheat powdery mildew.
Owner:QINGDAO AUDIS BIO TECH CO LTD
Botrychium ternatum micro-powder decoction pieces, Botrychium ternatum composition and preparation method of Botrychium ternatum composition
InactiveCN106619749AImprove the dissolution rate of total flavonoidsGood antipyretic effectPowder deliveryAntipyreticAlcoholBioavailability
The invention provides Botrychium ternatum micro-powder decoction pieces. The Botrychium ternatum micro-powder decoction pieces comprise Botrychium ternatum root micro-powder with the particle size being 65-170 meshes. The invention further provides a Botrychium ternatum composition. The Botrychium ternatum composition comprises the Botrychium ternatum root micro-powder with the particle size being 65-170 meshes and Botrychium ternatum stem and leaf extract, wherein the Botrychium ternatum stem and leaf extract is the water extract of Botrychium ternatum stems and leaves or the alcohol extract of the Botrychium ternatum stems and leaves. The Botrychium ternatum micro-powder decoction pieces and the Botrychium ternatum composition have the advantages that the dissolution rate of the effective component total flavonoids in the Botrychium ternatum micro-powder decoction pieces and the Botrychium ternatum composition is evidently increased as compared with that traditional decoction pieces, the problem that the main components especially flavonoid substances in Botrychium ternatum are hard to transfer is solved, and the bioavailability of the decoction pieces is increased; experiments show that the cough relieving, asthma relieving and fever abating effects of the Botrychium ternatum micro-powder decoction pieces and the Botrychium ternatum composition are evidently increased as compared with those of traditional Botrychium ternatum decoction pieces, and medicine taking quantity of patients is reduced.
Owner:黄萍
Method for preparing catalpol and derivative thereof based on radix rehmanniae praeparata and application
PendingCN112194691AReduce drug useIncrease tyrosinase activitySugar derivativesAntipyreticRehmanniae RadixPerylene derivatives
The invention discloses a method for preparing catalpol and a derivative thereof based on radix rehmanniae praeparata and application, and belongs to the technical field of medicines. According to themethod, the catalpol derivative is prepared by reacting a caffeic imide compound with the catalpol in anhydrous acetonitrile, wherein the caffeic imide compound is obtained by reacting caffeic acid with amino acids; and the amino acids include serine and threonine. The catalpol derivative obtained by the method has a blood sugar reducing effect, and the dosage of the catalpol derivative is smallwhile the same blood sugar reducing effect is achieved; moreover, the catalpol derivative has no toxicity to cells, and does not influence cell proliferation; moreover, the catalpol derivative has theeffect of improving the activity of tyrosinase, so that the activity of the tyrosinase at least reaches 140%; and the catalpol derivative also has a good analgesic effect, and the minimum mechanicalretraction threshold value reaches 35g.
Owner:河北仁心药业有限公司
Method for effectively extracting genomic DNA (deoxyribonucleic acid) of melaleuca alternifolia
InactiveCN108410857AImprove securityReduce drug useMicrobiological testing/measurementDNA preparationChemistryGenomic DNA
The invention provides a method for effectively extracting genomic DNA (deoxyribonucleic acid) of melaleuca alternifolia, which comprises the following steps: (1) grinding a sample into powder by liquid nitrogen, transferring the powder to a centrifuge tube, adding a DNA extraction buffer which is conventionally preheated, uniformly mixing and carrying out water bath at 65 DEG C for 30 minutes; (2) taking out the centrifuge tube and cooling to room temperature, adding a mixed solution of chloroform and isoamyl alcohol, uniformly mixing and performing centrifugal separation; (3) taking supernate, adding chloroform, uniformly mixing and performing centrifugal separation; (4) taking supernate, adding absolute ethyl alcohol which is conventionally precooled, uniformly mixing, standing for 30 minutes at -20 DEG C, then performing centrifugal separation, and discarding the supernate; (5) washing sedimentation with ethyl alcohol of which the volume concentration is 75%, drying at room temperature and adding a DNA dissolution buffer, and storing at -20 DEG C for standby use. The method provided by the invention is capable of effectively and rapidly extracting the genomic DNA of the melaleuca alternifolia which is high in purity and suitable for PCR detection, and the use of toxic chemicals in the extracting process is reduced.
Owner:GUANGXI FORESTRY RES INST
Acne treating compound Chinese medicine preparation
InactiveCN100574778CAntibacterial and antipruriticInhibition of keratinizationDermatological disorderMolluscs material medical ingredientsMentholSide effect
The acne treating compound Chinese medicine preparation is prepared with ginseng, pearl powder, honeysuckle, dahurian angelica root, almond and other eight kinds of Chinese medicinal materials. The preparation process includes washing the medicine materials, crushing, decocting, filtering, centrifuging to obtain supernatant, concentrating, adding pearl powder, menthol, far infrared nanometer ceramic powder, etc, high temperature sterilizing, adding glycerin and ethanol. It has functions of resisting bacteria, relieving itch, reducing oil secretion, etc. and thus obvious acne treating effect and no side effect.
Owner:许炎军
Automatic pesticide spraying control method and device for fruit tree pest control
ActiveCN113678811AImprove the efficiency of drug controlReduce drug useInsect catchers and killersPesticideAgricultural engineering
The invention discloses an automatic pesticide spraying control method and device for fruit tree pest control, and relates to the technical field of pest control. According to the technical scheme, the method is characterized by comprising the steps as follows: recognizing the insect pest category according to image information, and carrying out the statistics of the distribution probability; screening insect pests exceeding a set value as a first preparation category according to the distribution probability; collecting soil physical and chemical property information, and determining a priority value of the insect pest category according to a matching degree between the suitable growth range and the soil physical and chemical property information; screening out the insect pest category with the priority value exceeding an early warning value as a second preparation category; if the insect pest category only belongs to the first preparation category, carrying out upward rotary spraying of pesticide on the target object; if the insect pest category only belongs to the second preparation category, carrying out downward rotary spraying of the pesticide on the target object; and if the insect pest category belongs to the first preparation category and the second preparation category at the same time, carrying out upward and downward rotary spraying of pesticide on the target object. According to the invention, the source of insect pest categories can be visually reflected, so that the pesticide spraying device is flexibly controlled to carry out adaptive pesticide control.
Owner:POMOLOGY RES INST GUANGDONG ACADEMY OF AGRI SCI
Method for extracting saponins component from Yixinshu composition by supercritical fluid extraction method
InactiveCN109223966AHigh extraction rateReduce drug useCardiovascular disorderPlant ingredientsSupercritical fluid extractionChemistry
The invention relates to a method for extracting a saponins component from Yixinshu composition by a supercritical fluid extraction method and a product thereof, and specifically relates to pulverizing ginseng, radix Ophiopogonis, fructus Schisandrae Chinensis, radix astragali, radix Salviae Miltiorrhizae, rhizoma Ligustici Chuanxiong and fructus crataegi to 0.3-2.0 mm in prescription amount, drying at low temperature, extracting separately or mixing. The saponins in Yixinshu preparation were extracted with supercritical carbon dioxide as extractant, which provided saponins effective ingredients for the development of new preparation.
Owner:GUIZHOU XINBANG PHARMACEUTICAL CO LTD
Feed additive produced from waste liquid and dregs in pharmaceutical factory and preparation method of feed additive
ActiveCN103404709BPromote healthy developmentImprove immunityAnimal feeding stuffBiotechnologyDrug factories
The invention discloses a method for producing a feed additive from waste liquid and dregs in a pharmaceutical factory. The method comprises the following steps of inoculating an enterococcus faecalis seed solution with viable count of 2.5*10<10>-3.5*10<10> / ml on waste dregs mixed with waste liquid in the pharmaceutical factory, and carrying out solid fermentation under an aseptic condition, wherein the fermentation temperature is 37-39 DEG C, and the fermentation time is 40h-48h, 0.1ml-0.3ml of waste liquid, 0.1ml-0.3ml of enterococcus faecalis seed solution and 0.006g-0.015g of calcium carbonate are added to each gram of waste dregs, the waste liquid is generated in a lactasin fermentation process, and the waste dregs are Chinese medicine waste dregs generated during the production of Xiaoshuan enteric capsules. The feed additive provided by the invention can be taken as a substitute of antibiotic to be applied to breeding industry, can be used for improving the immunity of beasts and birds and reducing the morbidity to lower medicine consumption so as to achieve the effect of reducing the breeding cost, and is capable of promoting the healthy development of breeding industry.
Owner:吾方(新密市)医疗科技有限公司
Construction and applications of anti-influenza-virus or anti-inflammatory drug screening model based on in vitro culture of human lung particles
InactiveCN108690826AGood uniformityReduce drug useMicrobiological testing/measurementArtificial cell constructsAnti-inflammatoryFactor ii
The invention belongs to the technical field of medicine, and specifically discloses construction and applications of an anti-influenza-virus or anti-inflammatory drug screening model based on in vitro culture of human lung particles. According to the invention, lung tissue is cut into small particles with a size of 0.05-0.2 mm<3>, the small particles are uniformly sub-packaged in the form of a suspension, and the sub-packaged small particles are infected with influenza virus after in vitro culture is performed for a certain time; the experiment results prove that influenza virus can replicateefficiently in pig lung particle tissue and human lung particle tissue, and initiate the up-regulation of a series of inflammatory factors, and the known anti-influenza-virus drugs and the known anti-inflammatory drugs can inhibit influenza virus and inflammatory factors in the constructed lung particle tissue models and have dose effects; the construction method has characteristics of simple andrapid operation, time saving and labor saving, and the constructed model can substantially retain the tissue activity and reduce the waste of tissue, and is close to the physiological conditions of animals; and after the method is optimized, the anti-influenza virus or anti-inflammatory drug screening model can achieve the micro, rapid and uniform effect, and can accurately evaluate drugs.
Owner:WUHAN INST OF VIROLOGY CHINESE ACADEMY OF SCI
Application of tunicamycin in preparing tumour cell reversing drug
InactiveCN101530420BReduce drug useThe effect is accurateOrganic active ingredientsAntineoplastic agentsAntigenDifferentiation therapy
The invention relates to the technical field of medication. The tumour is always cured by operation, irradiation and chemical medication, and the induction differentiation therapy of malignant tumour becomes the research hotpot and frontier field of cancer biology and tumor therapeutics at present. The invention aims at providing a now application of tunicamycin which is the application in preparing a tumour cell reversing drug. The concentration of low-dosage tunicamycin adopted by the invention is 0.1-0.5mug / ml. After a myeloma cell line is treated, myeloma cell strain is differentiated in state, which is shown as cells are transited into mature plasma cell state; cell differentiation antigen CD49e is raised; and excreted immune globulin light chains are also increased. The invention has the advantages of low drug dosage of the tunicamycin, exact effect, less influence on normal cell and benefit for improving the living state of tumour patients.
Owner:SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
Wheat field herbicide composition
The present invention discloses wheat field herbicide composition with synergistic effect. The wheat field herbicide composition is a ternary composition comprising fenoxaprop-P-ethyl, tribenuion-methyl, fluoroglycoen-ethyl and filling; or a binary composition comprising fenoxaprop-P-ethyl, tribenuion-methyl or fluoroglycoen-ethyl, and filling. It may be prepared into oil suspension, wettable powder, water dispersed pellet, oil emulsion, water emulsion, dry suspension or tablet. It is used mainly for wheat field with seedlings to preventing and killing gramineous weeds and broad-leaved weeds and has acting time covering the whole wheat growth period.
Owner:SHANGHAI TAIHE INT TRADE CO LTD
A kind of insecticidal composition and its production method
ActiveCN107821431BStable and not easy to decomposeLong duration of actionBiocideAnimal repellantsPaichongdingOrganic solvent
Owner:江苏克胜集团股份有限公司
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