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Feed additive produced from waste liquid and dregs in pharmaceutical factory and preparation method of feed additive

A feed additive and traditional Chinese medicine waste residue technology, applied in animal feed, animal feed, application, etc., can solve problems such as unstable effects, drug residues, allergic reactions, etc., and achieve the effects of improving immunity, reducing emissions, and avoiding negative effects

Active Publication Date: 2014-11-05
吾方(新密市)医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(2) The problem of drug residues in livestock and poultry products; the human body often ingests low doses of antibiotic residues, which will gradually accumulate in the body and cause lesions in various organs, leading to allergic reactions, immunosuppression, teratogenicity, carcinogenicity, mutagenicity, etc.
Feed antibiotics substitutes that have been used in the breeding industry can be summarized into the following categories: (1) Probiotics are also called live bacterial preparations or microecological preparations (mainly Lactobacillus, Bifidobacterium, Bacillus, Yeast etc.), is a green feed additive with no toxic side effects and no residues. It has the effects of increasing weight gain and feed conversion rate, enhancing the immune function of the body, preventing and curing diseases, reducing mortality, and improving production efficiency. There are many studies, but the effect is not stable

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] (1) Preparation of medium:

[0021] Peptone 3.7%, glucose 4%, salt 0.5%, liver paste 0.5% kg, drinking water 90.3%. Heat the above-mentioned medium components (except glucose) in quantitative purified water to dissolve them, add glucose, then adjust the pH to 6.5, and distribute them in 50ml test tubes with 1% calcium carbonate, 1000ml triangular flasks, and 15000ml round In the bottom flask, put 25ml into each test tube, 450ml into each Erlenmeyer flask, and 9000ml into each round bottom flask, sterilize at 121°C for 30 minutes, and let it cool for later use.

[0022] (2) Preparation of liquid culture medium

[0023] Enterococcus faecalis strains (No. 140623, Latin scientific name: E. faecalis ) was inoculated in the above-mentioned test tube medium, cultured with shaking at 37°C for 24 hours, then inoculated into the culture medium of the Erlenmeyer flask with an inoculation amount of 2%, cultured with shaking at 39°C for 24 hours, and finally inoculated into the c...

Embodiment 2

[0026] (1) Preparation of medium:

[0027] Peptone 3%, glucose 3%, salt 0.5%, liver paste 0.5% kg, drinking water 92%. Heat the above-mentioned medium components (except glucose) in quantitative purified water to dissolve them, add glucose, then adjust the pH to 6.5, and distribute them in 50ml test tubes with 1% calcium carbonate, 1000ml triangular flasks, and 15000ml round In the bottom flask, put 25ml into each test tube, 450ml into each Erlenmeyer flask, and 9000ml into each round bottom flask, sterilize at 121°C for 30 minutes, and let it cool for later use.

[0028] (2) Preparation of liquid culture medium

[0029] Enterococcus faecalis strains (No. 140623, Latin scientific name: E. faecalis ) was inoculated in the above-mentioned test tube medium, cultured with shaking at 39°C for 20 hours, then inoculated into the medium of the Erlenmeyer flask with an inoculation amount of 5%, cultured with shaking at 39°C for 24 hours, and finally inoculated into the medium of the...

Embodiment 3

[0032] (1) Preparation of medium:

[0033] Peptone 4%, glucose 4%, salt 1%, liver paste 1% kg, drinking water 89%. Heat the above-mentioned medium components (except glucose) in quantitative purified water to dissolve them, add glucose, then adjust the pH to 6.5, and distribute them in 50ml test tubes with 1% calcium carbonate, 1000ml triangular flasks, and 15000ml round In the bottom flask, put 25ml into each test tube, 450ml into each Erlenmeyer flask, and 9000ml into each round bottom flask, sterilize at 121°C for 30 minutes, and let it cool for later use.

[0034] (2) Preparation of liquid culture medium

[0035] Enterococcus faecalis strains (No. 140623, Latin scientific name: E. faecalis ) was inoculated in the above-mentioned test tube medium, cultured with shaking at 38°C for 23 hours, then inoculated into the culture medium of the Erlenmeyer flask with an inoculation amount of 4%, cultured with shaking at 38°C for 22 hours, and finally inoculated into the culture m...

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Abstract

The invention discloses a method for producing a feed additive from waste liquid and dregs in a pharmaceutical factory. The method comprises the following steps of inoculating an enterococcus faecalis seed solution with viable count of 2.5*10<10>-3.5*10<10> / ml on waste dregs mixed with waste liquid in the pharmaceutical factory, and carrying out solid fermentation under an aseptic condition, wherein the fermentation temperature is 37-39 DEG C, and the fermentation time is 40h-48h, 0.1ml-0.3ml of waste liquid, 0.1ml-0.3ml of enterococcus faecalis seed solution and 0.006g-0.015g of calcium carbonate are added to each gram of waste dregs, the waste liquid is generated in a lactasin fermentation process, and the waste dregs are Chinese medicine waste dregs generated during the production of Xiaoshuan enteric capsules. The feed additive provided by the invention can be taken as a substitute of antibiotic to be applied to breeding industry, can be used for improving the immunity of beasts and birds and reducing the morbidity to lower medicine consumption so as to achieve the effect of reducing the breeding cost, and is capable of promoting the healthy development of breeding industry.

Description

technical field [0001] The invention belongs to the technical field of feed additive production, and in particular relates to a feed additive produced by using waste liquid and residue from a pharmaceutical factory and a preparation method thereof. Background technique [0002] CCTV’s exposure of “18 kinds of antibiotics” in KFC’s “instant chicken” incident left ordinary people dumbfounded. In the eyes of ordinary people, antibiotics are used for curing diseases and are harmful to human body, but in fact, adding antibiotics to feed is very common. matter. [0003] The use of antibiotics in farming can be traced back to the 1940s. In 1946, scholars such as Moore reported that adding antibiotics to feed could significantly increase the daily weight gain of broilers. Until today, antibiotics are still the most effective and stable growth-promoting additives, and feed antibiotics have made an indelible contribution to the rapid development of modern livestock and poultry indust...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23K1/16A23K1/00A23K1/14
Inventor 赵占武张少少赵一品赵晓棠邹吉祥
Owner 吾方(新密市)医疗科技有限公司
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