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46results about How to "Increase potential value" patented technology

Trajectory controlled indoor four-rotor unmanned aerial vehicle formation demonstration verification platform and method

The invention relates to the fields of unmanned aerial vehicles, embedded technologies and Wi-Fi wireless data transmission and aims to break through the poor capacity of responding to communication time and packet loss of a traditional demonstration verification platform, perform formation trajectory planning in real time according to the flight state of unmanned aerial vehicles and improve the formed flight demonstration effect of four-rotor unmanned aerial vehicles. Therefore, the adopted technical scheme is that a trajectory controlled indoor four-rotor unmanned aerial vehicle formation demonstration verification platform consists of an unmanned aerial vehicle side, a ground-based computer side and an indoor action capture system, combines with a distributed formation structure, obtains coming unmanned aerial vehicle flight trajectories and flight states through a wireless network, gives consideration to dynamical models of four-rotor unmanned aerial vehicles in an actual flight environment, designs a four-rotor unmanned aerial vehicle real-time trajectory planning method based on a differential flatness theory, cooperates with the indoor action capture system to achieve formedflight demonstration verification of multiple indoor four-rotor unmanned aerial vehicles. The platform is mainly applied to unmanned aerial vehicle control demonstration occasions.
Owner:TIANJIN UNIV

Amphoteric-cellulose-based composite material and application thereof

The invention discloses an amphoteric-cellulose-based composite material and application thereof. Quaternary ammonium-sulfonic acid cellulose serves as a carrier, grapheme oxide and chitosan are loaded in a blending manner, binding force among the three is utilized, and a quaternary ammonium-sulfonic acid cellulose / grapheme oxide / chitosan composite porous material is obtained through freeze drying. The quaternary ammonium-sulfonic acid cellulose / grapheme oxide / chitosan composite porous material comprises, by weight, 5-8 parts of quaternary ammonium-sulfonic acid cellulose, 0.5-3 parts of grapheme oxide and 0.5-3 parts of chitosan, is safe, non-poisonous and good in biocompatibility and degradability, has an orderly three-dimensional porous structure, good mechanical strength and efficient adsorption capability, can be used for water absorption and oil removal and processing of heavy metal ion waste water and organic waste water, and hopefully serves as a filtering material such as an air purification material and a medical adsorption material for use.
Owner:SUZHOU UNIV

Magnetic nanoparticle and immunomagnetic nanoparticle with cell-like structure as well as preparation method and application thereof

The invention discloses a magnetic nanoparticle and an immunomagnetic nanoparticle with a cell-like structure as well as a preparation method and application thereof. The magnetic nanoparticle with the cell-like structure uses a superparamagnetic Fe3O4 nanoparticle as a core and is wrapped with a white cell membrane on the surface, so that the magnetic nanoparticle has excellent magnetic responseperformance, furthermore, the white cell membrane wrapping on the surface of the magnetic nanoparticle is homologous with white cells, thereby effectively weakening non-specific adsorption to the white cell; an antibody is modified onto the white cell membrane wrapping on the surface of the magnetic nanoparticle through mediating of lipid molecules-polyethylene glycol-biotin molecules and avidin,so as to obtain the immunomagnetic nanoparticle with the cell-like structure. CTCs cells can be enriched and separated with high efficiency and high purity.
Owner:SICHUAN UNIV

Arrangements for awarding future prizes in an electronic game system

A method includes receiving a number of game play requests in a current game from one or more player stations. For some of the game play requests in the current game, a result in the current game is displayed at the respective player station from which the respective game play request was received. However, a respective future result is awarded for some game play requests. These future results may or may not have any present value, but are in any case associated with a play in a game to be conducted at some designated time in the future and thus represents at least some potential value. These future results are communicated to a respective receiving player at the player's respective player station to advise the receiving player that they have won a chance to participate in a future game.
Owner:MULTIMEDIA GAMES

Waste tire cracking device and method based on combination of dividing wall heat exchange and microwave heating

InactiveCN111471476AReduce the temperatureSolve the problem of large thermal resistanceProductsReagentsElectric machineSpiral blade
The invention discloses a waste tire cracking device and method based on combination of dividing wall heat exchange and microwave heating. The main body of the cracking device is a horizontal cylindrical shell (12); a spiral conveying device (3) is arranged on the left side of the shell; the right half section of the spiral conveying device is positioned in the shell; a feeding opening (2) is arranged in the upper part of the left side of the spiral conveying device; the spiral conveying device is driven by a first speed regulating motor (1.1); a pyrolytic carbon black collecting box (11) is arranged at the lower end of the right side of the shell, an electric heating device (6) is installed on the front section outside the shell, a microwave heating device (9) of a microwave heating section is installed on the rear section outside the shell, four supporting frames (4) are arranged on the lower portion of the shell to support the whole device, and spiral blades (13) are arranged in theshell and penetrate through the shell from left to right. The spiral structure is used for conveying materials, so that the material adaptability of the reactor is improved; and the waste tire particles are slightly carbonized in the continuous temperature rising process of front-section electric heating, so that the wave absorbing property of the waste tire particles is greatly improved.
Owner:SOUTHEAST UNIV

Formula of antiseptic and preservative agent composition containing ferulic acid butyl ester and application thereof

The present invention discloses a formula of an antiseptic and preservative agent composition containing ferulic acid butyl ester. The formula comprises 1-2 parts of ferulic acid butyl ester, 1-2 parts of silver carp fish scale collagen peptides, 1-2 parts of EDTA disodium, 0.5-1 part of a jasmine extract and 4-5 parts of pullulan. The present invention also discloses an application of the antiseptic and preservative agent composition formula in food processing, especially the application of the antisepsis and preservation of salmons. The formula effectively solves the problems that the salmons are easy to be spoiled and off-odor, change color and lose water. Besides, the processed salmons are fresh and bright in color, clear in texture, flexible in muscles and firm in flesh in relativelylong time. The developed solid preservative is more convenient to apply and transport. The produced salmons are long in storage period and relatively high in safety, and meet the market demands.
Owner:ZHEJIANG GONGSHANG UNIVERSITY

A kind of ion concentration polarization chip based on graphene porous membrane and preparation method thereof

The invention provides an ion concentration polarization chip based on a graphene porous membrane and a preparation method of the ion concentration polarization chip and relates to ion concentration polarization chips. The ion concentration polarization chip comprises a glass base, PDMS substrates, a buffer solution water inlet / outlet and a graphene-based porous membrane in a first PDMS substrate, wherein the first PDMS substrate is provided with a Y-shaped groove, and a second PDMS substrate is provided with an I-shaped groove. The preparation method comprises the following steps: preparing graphene-based precursor slurry; producing a chip; and smearing a notch of a Y channel with the graphene-based precursor slurry, and curing, so as to obtain the ion concentration polarization chip. The preparation method has the beneficial effects that the process is simple, and the chip is low in cost and easy to prepare; graphene materials are weakly acidic and have low damage to devices; and the conductivity of the graphene materials is conveniently regulated and controlled, surface functional groups and electric charges are easily regulated and controlled, and the graphene materials can be composited with a large number of materials so as to prepare composite films and devices. Compared with a NaFion-base chip, a relatively stable and relatively large-range exhaustion region can be formed by the graphene-based chip.
Owner:XIAMEN UNIV

Tyre static unbalance improvement method based on vector calculation

The invention relates to a tyre static unbalance improvement method based on vector calculation. The method comprises the following steps: S1) carrying out forming process; S2) carrying out vulcanization, detection and screening; S3) measuring and calculating the position of each joint with respect to a static imbalance heavy point, the static imbalance heavy point being in a 180-degree angle with a static imbalance light point; S4) obtaining influence of each joint on static unbalance according to vector analysis; and S5) based on the calculation result above, reasonably arranging the joints according to the parallelogram law. For the problem of inherent static unbalance of each tyre itself, the method carries out analysis on the detection result through a vector calculation method, and carries out accurate calculation on three unavoidable key factors (1# cord joint, PA joint and tyre surface joint) affecting the static unbalance in the manufacturing process, so that an ideal improvement scheme can be obtained directly; in the implementation process, effects of short time, high efficiency and easy operation are achieved; and the obtained adjustment scheme is supported by accurate technical support.
Owner:山东省三利轮胎制造有限公司

Attapulgite strengthened and toughened sanitary ceramic green body and preparing method thereof

The invention discloses an attapulgite strengthened and toughened sanitary ceramic green body and a preparing method thereof. The sanitary ceramic green body is prepared from a green body material andattapulgite mineral nanofibers, wherein the attapulgite mineral nanofibers account for 1-4% of the mass of the green body material. The green body material is prepared from 1-6% of knar clay, 8-16% of Qinyang clay, 9-16% of kaolin, 9-16% of ball clay, 9-16% of Zhangcun clay, 9-16% of porcelain stone, 4-11% of porcelain clay, 4-11% of clay, 14-21% of feldspar, 1-6% of talcum and 1-6% of waste porcelain powder. The developed strengthened and toughened sanitary ceramic green body containing the natural nanofibers has the advantages of being simple in process, low in cost, capable of bringing small environmental loads and the like.
Owner:HEBEI UNIV OF TECH +1

Preservative fresh keeping agent formula rich in hexalactone ferulate and application

The invention discloses a preservative fresh keeping agent formula rich in hexalactone ferulate. The preservative fresh keeping agent formula comprises 1-2 parts of hexalactone ferulate, 1-2 parts ofsilver crap scale collagen peptide, 0.5-1 part of a jasmine flower extract, and 4-5 parts of pullulan polysaccharide. The invention further discloses an application of the preservative fresh keeping agent composition formula to medicinal plant raw materials and food processing, particularly an application of the preservative fresh keeping of fresh dendrobium candidum strips. According to the formula and the application thereof, the problems that the fresh dendrobium candidum strips are rotten, change color, dehydrate and the like during storage are effectively solved, the efficacy of the treated fresh dendrobium candidum strips can be maintained for a long time, and the herbal medicine taste of the fresh dendrobium candidum strips can also be effectively reduced. The developed solid freshkeeping agent is convenient to apply and transport, the produced fresh dendrobium candidum strips can be stored for a long time, the nutrient value and the safety are high, and the preservative freshkeeping agent formula meets market requirements.
Owner:ZHEJIANG GONGSHANG UNIVERSITY

Super-capacitor based on activated carbon/sodium copper chlorophyllin composite electrode and preparation method of super-capacitor

The invention relates to a super-capacitor based on activated carbon / sodium copper chlorophyllin composite electrodes. The super-capacitor comprises an electrolyte, the upper side of the electrode isprovided with a current collector and an electrode from top to bottom, the lower side of the electrode is provided with an electrode and a current collector from top to bottom, and the electrodes arethe activated carbon / sodium copper chlorophyllin composite electrode. According to the super-capacitor, activated carbon is a frequently-used super-capacitor electrode material, the activated carbon and sodium copper chlorophyllin are rich in source, low in cost, green and environmentally friendly, the sodium copper chlorophyllin can serve as an electrode material of super-capacitor to be used andserves as conductive agents in the composite electrodes, and the sodium copper chlorophyllin can replace relatively high-cost conductive agents for other activated carbon electrodes when the performances of the super-capacitor are kept, so that the manufacturing cost of the super-capacitor based on activated carbon is reduced.
Owner:FUJIAN AGRI & FORESTRY UNIV

Method for recovering whey protein or protein in MPC through complex enzyme polymerization coupling ultrafiltration

The invention relates to an effective method for simultaneously improving the recovery rate of whey protein or protein in MPC, improving the membrane flux and reducing the lactose retention rate through complex enzyme polymerization coupling ultrafiltration. Concretely, laccase and transglutaminase are sequentially added; complex enzyme polymerization and ultrafiltration are effectively combined; a two-section type pretreatment mode is creatively used before complex enzyme polymerization; the mode that the enzyme is not deactivated after the laccase action is also combined, so that the purity and the recovery rate of the whey protein or the protein in the MPC is greatly improved; the membrane flux is improved; the lactose retention rate is reduced. Compared with the prior art, the method has the advantages that the recovery rate of the whey protein or the protein in the MPC is improved by 20 percent; the membrane flux is improved by 30 percent to 40 percent; the lactose retention rate is reduced by 10 percent; the method capable of simultaneously solving a plurality of problems is obtained. The invention also provides a high-quality product of the whey protein or the protein in the MPC; the condition that the product sensitization is obviously reduced is accidentally found; the effect is realized through the result of the complementary and synergic action of all work procedures and parameters; the operability of the method is high; only once filtering is performed; the industrialization is facilitated.
Owner:OCEAN UNIV OF CHINA

Method and device for cavitation-erosion accumulation processing

The invention discloses a method and a device for cavitation-erosion accumulation processing, and relates to the technical field of material decrease manufacturing processing. According to the method and the device, which are disclosed by the invention, a cavitation effect is generated by virtue of a high-pressure water jet to carry out exfoliation erosion processing on a workpiece, and a needed shape is formed through accumulation. The device disclosed by the invention comprises a jet generation system, a high-pressure submerging system, a water pool (1), a high-pressure hose (13) and a filter (2). According to the method and the device, which are disclosed by the invention, a bubble cluster of the high-pressure water jet is collapsed due to a stagnation pressure generated by the stagnation of the workpiece while moving to the surface of the workpiece, about 5000+ / -200K of heat points are generated for material melting and weakening, thus a fatigue threshold value of a material is reduced; and fatigue fracture of the material is caused and circular block-shaped exfoliation erosion is formed under the composite action of high-frequency high-pressure shock waves, thus material decrease manufacturing is realized. The device disclosed by the invention is simple in structure, easy to maintain, low in cost and less in environmental influence. The method and the device, which are disclosed by the invention, are capable of processing various difficult-to-form materials and micro parts.
Owner:JIANGSU UNIV

Method for preparation and transformation of wheat endosperm cell protoplast

The invention discloses a method for preparation and transformation of a wheat endosperm cell protoplast. The invention provides a method for preparing the wheat endosperm cell protoplast, comprisingthe following steps of: taking fresh wheat grains 8-11 days after flowering, splitting along abdominal seams to obtain endosperm tissues, soaking and washing in a buffer solution 1, then putting in abuffer solution 2 for enzymolysis, and carrying out ice bath standing time gradient sedimentation to obtain a purified wheat endosperm cell protoplast. The invention provides an efficient, economicaland rapid protoplast preparation and transformation method for wheat endosperm cells containing a large number of stored starch particles. According to the method, the endosperm cell protoplast can berapidly and effectively separated; the method can be used for subcellular localization, transcription factor activity analysis, protein interaction identification and enzyme activity analysis of wheat endosperm expression factors, creates conditions for in-vivo molecular biological research of the factors, and effectively avoids experimental deviation caused by error expression of endosperm specific expression genes in other cells.
Owner:CAPITAL NORMAL UNIVERSITY

A charging method for mobile communication service

The invention relates to a charging method of the mobile communication service, which comprises the following steps: firstly, a mobile communication system provides a Dutch treatment charging mode selection function for a mobile communication user, when the user applies for the Dutch treatment charging mode, the system prompts the user to provide the relative user data and stores the relative user data provided by the user; secondly, the mobile communication system provides a Dutch treatment communication interface at a mobile communication terminal, when the user inputs the number of the other terminal from the Dutch treatment communication interface of one terminal, the system judges whether the Dutch treatment charging mode is applied for the number according to the stored user data; thirdly, to the number for which the Dutch treatment charging mode is applied, if the user confirms that the number is used for the communication, the system calculates the relative communication cost from the count of a terminal number.
Owner:ZTE CORP

Acrylic resin containing amphipathic lateral chain, and preparation and use thereof

InactiveCN101412779BGood antifouling activityExcellent marine antifouling activityAntifouling/underwater paintsPaints with biocidesMethacrylateAcrylic resin
The invention relates to acrylic resin containing amphiphilic lateral chains, a preparation method thereof and application of the acrylic resin containing the amphiphilic lateral chains. The general structural formula of the acrylic resin containing the amphiphilic lateral chains is as shown in a figure 1. The preparation method comprises the following steps: (1) dichloromethane, tetraethylene glycol and triethylamine are added, acryloyl chloride is slowly dripped into the mixture under the protection of nitrogen, and the mixture is subjected to temperature rise and stirring; (2) ester obtained in the step (1) is dissolved in anhydrous dichloromethane, dipped with acyl fluoride containing perfluor polyether chains, and stirred at a temperature of 80 DEG C below zero and 25 DEG C; and (3) 100 to 150 millimeters of tetrahydrofuran and 800 to 900 milligrams of initiator are added, and the mixture is subjected to temperature rise to between 60 and 80 DEG C, added with 15 to 20 grams of methacrylic ester, 12 to 15 grams of glycidyl methacrylate and 15 to 25 grams of acrylic acid derivatives under the protection of the nitrogen, stirred, subjected to temperature rise to between 65 and 80 DEG C, maintained at a constant temperature for 48 to 72 hours to obtain the acrylic resin containing the amphiphilic lateral chains. The resin not only can be taken as a film former of marine antifouling coating but also has nontoxic and eco-friendly performance.
Owner:DONGHUA UNIV

Method and device for controlling milling deformation of large sized structural member

The invention discloses a method and a device for controlling milling deformation of a large sized structural member, belonging to the part processing deformation control in the field of mechanical engineering. The control method is characterized by comprising the following steps of: simultaneously spraying cooling liquid on the rear part of a milling cutter when the cooling liquid is sprayed on the front part of the milling cutter, and rolling by using a deformation controller. The invention can be used for effectively releasing stress deformation generated in the milling process of the large sized structural member so as to achieve the purpose of controlling the processing deformation of the large sized structural member.
Owner:NANJING UNIV OF AERONAUTICS & ASTRONAUTICS

Slag modification reducer and preparation method thereof, and method for Fe recovery with slag waste heat

The invention discloses a slag modification reducer. The slag modification reducer is shaped like spherical particles with a particle diameter of 10-30 mm and comprises 100 parts by weight of a fusionagent, 5-24 parts by weight of a reduction agent, 8-18 parts by weight of a binder and 0-10 parts by weight of a fluxing agent. The invention also discloses a method for Fe recovery with slag waste heat. The method comprises the following steps: (a) during a course when slag is discharged from a smelting furnace and poured into a heat-preservation container, the slag modification reducer is addedinto a slag flow, and a modified reduction reaction takes place; and (b) after the slag completes the reaction with the modification reducer, solid slag in the heat-preservation container is crushed,and metal Fe particles and / or Fe ore concentrate powder are obtained through magnetic separation. The method aims at the fact that the slag contains a lot of waste heat and residual Fe resources, directly conducts high-temperature waste heat modification of the slag, adjusts chemical components and a smelting temperature of the slag, reduces reduction potential energy of Fe oxides and then uses amiddle-low temperature roasting temperature and a grinding-separation technology to realize efficiency recovery of Fe in the slag.
Owner:CHINA ENFI ENGINEERING CORPORATION

Mobile telephone tracking and anti-theft service system

The invention relates to a tracking and anti-theft service system used in mobile phone, which comprises an HLR, a VLR, a mobile base station, a short message center and a receiving terminal of customer mobile phone information and mobile phone position information; the HLR, the VLR, the mobile base station and the short message center belong to a mobile communication system; the HLR is adopted to set and manage marker bit of tracking and anti-theft service for customer mobile phone and activate the tracking and anti-theft service according to user request to sent the activation information of customer mobile phone to the VLR; the VLR is used for sending the activation information from the HLR to customer mobile phone through the mobile base station and sending the position information returned from customer mobile phone to a designated position information receiving terminal; the customer mobile phone is adopted to receive service activation information transmitted from a mobile base station, by which the position information of the mobile phone is sent back to the VLR; the mobile base station is for transmitting information between the customer mobile phone and the VLR; the position information receiving terminal is used to receive customer position information from the VLR.
Owner:ZTE CORP

Method for establishing life cycle evaluation database

The invention provides a method for establishing a life cycle evaluation database, and belongs to the field of life cycle evaluation databases. The method comprises the steps of formatting the unit process list initial data according to a life cycle evaluation database data standard to obtain unit process list data corresponding to an enterprise production and consumption process; encoding the unit process list data corresponding to the enterprise production and consumption process by using an industry classification standard to obtain source data of industry-level life cycle evaluation database construction corresponding to multiple industries; obtaining average unit process list data corresponding to the enterprise production and consumption process in the industry by utilizing the source data; and associating the identification directory with the average unit process list data corresponding to the enterprise production and consumption process in the industry to obtain a life cycle evaluation database. By automatically optimizing the life cycle evaluation database, the effectiveness of environmental impact evaluation and the potential value of the life cycle evaluation database are improved.
Owner:ZHEJIANG UNIV

Dry space wet space separated facial mask, and preparation method and applications thereof

The invention relates to a dry space wet space separated facial mask, and a preparation method and applications thereof. The dry space wet space separated facial mask comprises a dry facial mask containing polypeptide liposome. According to the preparation method, polypeptide liposome freeze-dried powder is prepared into a suspension liquid, the suspension liquid is sprayed onto blank facial maskpaper, and drying is carried out so as to obtain a finished product. The dry space wet space separated facial mask is convenient to carry, contains no antiseptic, and is relatively high in practical value and potential value.
Owner:DONGHUA UNIV

Method for realizing multifunctional speed measurement of rotating mechanism based on logic controller

The invention relates to the field of output rotating shaft angular velocity measurement of a to-be-measured object. The invention discloses a method for realizing multifunctional speed measurement of a rotating mechanism based on a logic controller. A coded disc is prepared according to the diameter of an output rotating shaft of a to-be-measured object; a proximity switch is installed on the to-be-measured object, a transmitting head and a receiving head of the proximity switch are aligned with the through hole circle of the coded disc, and the proximity switch is connected with a PLC; and the PLC receives signals of the proximity switch to form pulses, the total pulse number A is obtained in a time period T, the angular velocity [omega] of the output rotating shaft of the object to be measured is equal to 2[pi]*A / (T*N), N is the number of the through holes, and [pi] is the circumference ratio. Various defects existing in a complex industrial field environment when a traditional integrated pulse speed measuring device is used are overcome.
Owner:SHANXI TAIGANG STAINLESS STEEL CO LTD

Metal material obtained by method for regulating and controlling crystal face orientation of metal coating and application of metal material

The invention relates to a metal material obtained by a method for regulating and controlling the crystal face orientation of a metal coating and application of the metal material. Firstly, a metal substrate which is simple, cheap and easy to obtain and has specific crystal orientation is screened out, then the metal substrate serves as a reducing agent, a thin metal coating is plated through a chemical soaking method, and the crystal face orientation of the metal coating can be controlled through the crystal orientation of the substrate; the method can be used to prepare a highly preferred, even fully preferred metal coating. Finally, the plating layer with the specific crystal orientation is successfully used for improving the deposition-stripping reversibility of a metal negative electrode and the activity of an electrode catalytic interface.
Owner:CENT SOUTH UNIV

A method for reclaiming protein in whey protein or MPC by compound enzyme polymerization coupling ultrafiltration

The invention relates to an effective method for simultaneously improving the recovery rate of whey protein or protein in MPC, improving the membrane flux and reducing the lactose retention rate through complex enzyme polymerization coupling ultrafiltration. Concretely, laccase and transglutaminase are sequentially added; complex enzyme polymerization and ultrafiltration are effectively combined; a two-section type pretreatment mode is creatively used before complex enzyme polymerization; the mode that the enzyme is not deactivated after the laccase action is also combined, so that the purity and the recovery rate of the whey protein or the protein in the MPC is greatly improved; the membrane flux is improved; the lactose retention rate is reduced. Compared with the prior art, the method has the advantages that the recovery rate of the whey protein or the protein in the MPC is improved by 20 percent; the membrane flux is improved by 30 percent to 40 percent; the lactose retention rate is reduced by 10 percent; the method capable of simultaneously solving a plurality of problems is obtained. The invention also provides a high-quality product of the whey protein or the protein in the MPC; the condition that the product sensitization is obviously reduced is accidentally found; the effect is realized through the result of the complementary and synergic action of all work procedures and parameters; the operability of the method is high; only once filtering is performed; the industrialization is facilitated.
Owner:OCEAN UNIV OF CHINA

A charging method for mobile communication service

The invention relates to a charging method of the mobile communication service, which comprises the following steps: firstly, a mobile communication system provides a Dutch treatment charging mode selection function for a mobile communication user, when the user applies for the Dutch treatment charging mode, the system prompts the user to provide the relative user data and stores the relative user data provided by the user; secondly, the mobile communication system provides a Dutch treatment communication interface at a mobile communication terminal, when the user inputs the number of the other terminal from the Dutch treatment communication interface of one terminal, the system judges whether the Dutch treatment charging mode is applied for the number according to the stored user data; thirdly, to the number for which the Dutch treatment charging mode is applied, if the user confirms that the number is used for the communication, the system calculates the relative communication cost from the count of a terminal number.
Owner:ZTE CORP

Preparation method of cellulose-based insoluble or slightly soluble drug sustained-release microspheres

The invention discloses a preparation method of cellulose base water-insoluble or slightly-soluble drug slow release microspheres. The preparation method comprises steps of performing oxidization withsodium periodates to obtain dialdehyde cellulose, and performing ageing on the dialdehyde cellulose at a certain temperature so as to obtain a nanocellulose solution; and performing reductamination with arginine or arginine salt so that dialdehyde cellulose DAC becomes cellulose base hollow nanometer microspheres with positive charges on the surface, then using the cellulose base hollow nanometermicrospheres as a nucleator, forming cellulose base mineralized microspheres, and finally, by a solvent evaporation method, enabling medicines which are soluble in ethanol but insoluble or slightly soluble in water to be packed in the microspheres, so as to prepare the drug slow release microspheres.
Owner:XIAMEN UNIV

A Practical Method for the Synthesis of Novel Bioactive Molecules Using N-Methoxyamides as Nitrogen Sources

The invention discloses a practical method for synthesizing novel biologically active molecules using N-methoxyamide as a nitrogen source. In a glass reaction tube, aryl-substituted nitrogen heterocyclic compounds, dichloro(pentamethylcyclopentadiene) Alkenyl) iridium (III) dimer, silver hexafluoroantimonate, and N-methoxybenzamide, using 1,2-dichloroethane as a solvent, reacting at 120-140°C to obtain use N‑methoxyamides as nitrogen sources for the synthesis of novel bioactive molecules. There are various types of products obtained by the method of the present invention, which can be directly applied to the synthesis and modification of drug molecules and can be used in other further reactions; meanwhile, the synthetic route is safe and easy, the cost is low, and the reaction operation and post-treatment process are simple , Good selectivity, methanol is the only by-product, in line with the concept of green chemistry.
Owner:SUZHOU UNIV

Mild cognitive function impairment diagnostic marker, kit and application thereof

The invention relates to a marker for auxiliary diagnosis of peripheral blood in a profenodic stage of Alzheimer's disease, namely mild cognitive impairment (MCI), the marker is plasma CircRNA (Ribonucleic Acid), and the plasma CircRNA comprises circ-0004738, circ-0001490, circ-0003362, circ-0008289 and circ-0074719. The marker for auxiliary diagnosis of the peripheral blood in the profenodic stage of the Alzheimer's disease is a marker for auxiliary diagnosis of the peripheral blood in the profenodic stage of the Alzheimer's disease, and the marker for auxiliary diagnosis of the peripheral blood in the profenodic stage of the Alzheimer's disease is a marker for auxiliary diagnosis of the peripheral blood in the profenodic stage of the Alzheimer's disease. The invention also relates to application of the marker and a corresponding kit. The peripheral plasma CircRNA biomarker has the beneficial effects that the peripheral plasma CircRNA biomarker with relatively high diagnostic value on the Alzheimer's disease prophase, namely mild cognitive impairment is found, the MCI peripheral blood non-coding RNA diagnostic marker spectrum is enriched, and the early diagnosis and early intervention of MCI are facilitated.
Owner:SHANGHAI MENTAL HEALTH CENT (SHANGHAI PSYCHOLOGICAL COUNSELLING TRAINING CENT)

A kind of enzyme-free superoxide anion electrochemical sensor and its preparation method and application

The invention provides a production method of an enzyme-free superoxide anion electrochemical sensor. The production method comprises the following steps: functionalizing multi-walled carbon nano-tubes with L-cysteine to obtain Cys-MWCNTs, and depositing silver nano-particles on the surface of a Cys-MWCNTs modified electrode through an electrochemical technology to obtain the enzyme-free superoxide anion electrochemical sensor. The invention also provides the enzyme-free superoxide anion electrochemical sensor produced through the method, and an application of the enzyme-free superoxide anion electrochemical sensor. The catalysis effect of the silver nano-particles on active oxygen is used to substitute SOD enzyme for the first time in order to detect superoxide anions. The method has the advantages of simplicity, easiness in operation, difficult inactivation and realization of long-term preservation and use. The modified electrode is successfully applied to detection of the superoxide anions released by living cells (PC12). The modified electrode constructed in the invention has the characteristics of very good electrochemical response to O<2>.<->, wide linear range, high sensitivity, short response time, good stability and good repeatability.
Owner:菏泽智慧新材料科技有限公司
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