194results about How to "Active ingredients are clear" patented technology

An extract of mulberry twigs is dislcosed, which can be used to prepare the food or the medicine to cure hyperuricemia and gout diseases. The said extract is prepared from mulberry twigs through extracting in solvent (aqueous solution of alcohol, chloroform, acetone, etc) at 10-100 deg.C more than one time, mergint the liquid extracts, recovering solvent, regulating pH value to 7.5-9.5, centrifugal separation to obtain supernatant, regulating pH value to 4-6, deposition, water washing wand drying. Several other approaches for purifying it are also disclosed.

The invention relates to a total sesquiterpene lactone extract containing rich parthenolide and the preparation method and application thereof. Particularly, the invention relates to a method of extracting sesquiterpene lactone containing rich parithenolide from yulan magnolia leaves and / or flower; yulan magnolia leaves and / or flower are taken as raw materials, crushed, extracted by polarity organic solvent and non-polarity organic solvent so as to get yulan magnolia total lactone; the yulan magnolia total lactone is processed with columnchromatography, and then the invention extract is obtained by collecting necessary components. The invention has definite effective components, the content of which is high, and is suitable for industrialized production. The invention has the anti-tumor virus function. The invention can be prepared into various pharmaceutical preparations with anti-tumor function.

The invention relates to a preparation method of effective fractions of shining wintersweet leaf, a preparation method and a use of a preparation thereof, in particular to an application of the effective fractions of the shining wintersweet leaf and the preparation thereof in drugs used for preventing and treating respiratory system diseases as well as in anti-cold drugs, antimicrobial drugs, anti-inflammation drugs, antiviral drugs, antifungal drugs, etc. In the invention, the volatile effective fractions and non-volatile effective fractions are added to the crude drug of the shining wintersweet medicinal material with a weight ratio of the actual extraction amount of the shining wintersweet to the effective fractions being 1.0-2.6:0.5-3.5, thus the effective fractions of the shining wintersweet leaf are obtained. A preparation of the effective fractions of the shining wintersweet can be made into granules, soft capsules, capsules, drop pills, tablets, compound capsules, dispersible tablets, etc. In the invention, the preparation of the shining wintersweet is deeply developed, which ensures that the preparation is rich in active ingredients, has definite effective ingredients, obvious pharmacological action and significant improvement of drug action. Besides, the preparation has stable performance and controllable quality, is safe and reliable, has less dosage, and is favorable for transportation and storage of the medicine as well as for patients to take.

The invention relates to a double coptis for injection as a veterinary herbal medicine compound preparation and a preparation technique as well as an application thereof. The compound preparation is made from the following parts of medicines by weight: 1250 portions to 3750 portions of honeysuckle, 1250 portions to 3750 portions of scutellaria and 2500 portions to 7500 portions of forsythia. Sustained release accessories contain 200 portions of hydroxypropyl methylcellulose and 100 portions of sodium carboxymethylcellulose. The containing of sustained release accessories can reduce injection times for large animals and the stress response of large animals. The veterinary herbal injection preparation has the functions of antiviral, antibacterial, anti-inflammatory and antipyretic analgesic effects, as well as improving immunity and the like, and can be applied to epidemic diarrhea, transmissible gastroenteritis, swine paratyphoid, septicemia caused by various diseases, cough, dyspnea, skin cyanosis, arthrocele, lameness, swine reproduction and respiratory disturbance syndrome and cow mastitis caused by streptococcosis, haemophilus parasuis infection, contagious pleuropneumonia, swine lung plague in veterinarian clinical practice.

The invention discloses a drug compound for preventing and curing diabetes mellitus, which at least comprises two components including Timosaponin B-II and berberine. Preventing and curing effect can be improved by adding one or a plurality of components from mangiferin, Timosaponin A-III and Timosaponin B-III. The drug compound can also be compounded by anemarrhena extractive and golden cypress extractive, or can be directly extracted from anemarrhena and golden cypress. The drug compound has the advantages of obvious blood sugar reduction effect, and high effective component content, easy quality control. The preparation process of the drug compound is easy for industrialization, and can be applied as drugs to prevent and cure diabetes mellitus.

The invention aims to develop medicinal composition fat emulsion injection containing eucalyptol, limonene and alpha-pinene and a preparation method. The preparation comprises the following components in percentage by weight: 0.0128 to 0.0320 percent of eucalyptol, 0.0084 to 0.0210 percent of limonene, 0.0028 to 0.0070 percent of alpha-pinene, 10 to 30 percent of soybean oil for injection, 1.0 to 1.5 percent of yolk lecithin for injection or 0.8 to 1.5 percent of soybean phospholipids for injection, 2.0 to 2.5 percent of glycerol for injection, and water for injection added to 100 milliliters. The preparation method has the characteristics of strong controllability of production quality, and definite treatment effect of a product. The invention fills up the blank of the medicinal composition fat emulsion injection preparation containing the eucalyptol, the limonene and the alpha-pinene.

The invention discloses a prepared traditional Chinese medicinal preparation having anticancer reactivity, which is an extraction containing saponin prepared from Marsdenia tenacissima, a traditional Chinese medicinal Asclepiadaceae plant through refining. The invention also discloses the process for preparing the traditional Chinese medicinal preparation having anticancer reactivity and its use.

A Chinese patent medicine for treating rheumatoid arthritis, relieving inflammation and relaxing pain is prepared from oriental bittersweet stem through extracting and separating.

The invention provides application of a panaxadiol saponins fraction in preparing a medicine for preventing dermatitis and scar and a health-care cosmetic. The panaxadiol saponins fraction comprises the following main constituents: ginsenoside Rb1, ginsenoside Rb2, ginsenoside Rb3, ginsenoside Rc and ginsenoside Rd. The medicine or the cosmetic is prepared from active constituents in the single panaxadiol saponins fraction or / and other medicines together and a pharmaceutically acceptable or cosmetic acceptable carrier. The medicine or the cosmetic is prepared by utilizing raw materials: ginseng rhizome medicinal materials, American ginseng rhizome medicinal materials, ginseng stem leaf medicinal materials, American ginseng leaf medicinal materials and total extractives or total saponins of the ginseng rhizome medicinal materials, the American ginseng rhizome medicinal materials, the ginseng stem leaf medicinal materials and American ginseng leaf medicinal materials through a chromatographic separation and purification method combining macroporous resin column chromatography and octadecylsilane chemically bonded silica column chromatography. The scar can be prevented from forming while the tissue regeneration and repair are promoted by the medicine or the cosmetic. Compared with glucocorticoids, cellular immunity is integrally regulated, the drug action is stable after the medicine is suspended, and the drug action advantage is obvious. The medicine or the health-care cosmetic is highly safe. The structural formula of panaxadiol saponins is shown in the specification.

The effective Chinese medicine part composition has the functions of benefiting vital energy, nourishing Yin, etc. The effective Chinese medicine part composition features that it includes total ginsenoside, total ophiopogonin, volatile schisandra oil and total schisandra lignin.

The invention relates to a composition containing 50 to 99 parts by weight of arctiin with the purity of more than 90 percent or 1 to 50 parts by weight of arctigenin and a preparation method thereof, and the functions of the composition are the treatment and the prevention of diabetic retinopathy. In the invention, by extracting the arctiin and the arctigenin, the pharmacological, toxicological and clinical trial results show that the composition of arctiin or arctigenin of the invention has the advantages of strong treatment effect and small toxicity and side effects in the treatment of the diabetic retinopathy.

The invention belongs to the technical field of natural herbal medicines and particularly relates to an extract of a plant in blumea as well as a preparation method and application thereof. The extract contains 10-99wt% of total caffeoylquinic acid. The preparation method of the extract comprises the following steps: (S1) pulverizing the plant in blumea wholly or partially, and extracting with an organic solvent, water or the solution of the organic solvent in water to obtain a crude extract; and (S2) extracting the crude extract with n-butanol or purifying with a macroporous adsorption resin column to obtain the extract of the plant in blumea. The extract provided by the invention has a good antiviral effect, can be used for preparing medicines for preventing and treating virus infection and health care products, is definite in effective components, low in toxicity and strong in pharmacologic action and has good application prospect. In addition, the preparation process of the extract is simple and is suitable for large-scale production.

The invention relates to a Chinese herbal medicine compound preparation for treating skin and mucous membrane disease. The Chinese herbal medicine compound preparation is prepared from the following raw materials: cortex moutan, polygonum chinense, radix salviae miltiorrhizae, herba lycopi, common dayflower herb, rhizoma smilacis glabrae, ramulus cinnamomi, caulis dendrobii officinalis, gorgon fruit and cortex cinnamomi; the ingredient of the Chinese herbal medicine compound preparation comprises a cortex moutan extract, a polygonum chinense extract, a radix salviae miltiorrhizae extract, a herba lycopi extract, a common dayflower herb extract, a rhizoma smilacis glabrae extract, a ramulus cinnamomi extract, a caulis dendrobii officinalis extract, a gorgon fruit extract and a cortex cinnamomi extract; and the effective ingredient of the cortex moutan extract is paeonol, the effective ingredient of the polygonum chinense extract is quercitrin, the effective ingredient of the radix salviae miltiorrhizae extract is tanshinone IIA, the effective ingredient of herba lycopi is ursolic acid, the effective ingredient of common dayflower herb is commelinin, the effective ingredient of rhizoma smilacis glabrae is astilbin, the effective ingredient of ramulus cinnamomi is cinnamaldehyde, the effective ingredient of caulis dendrobii officinalis is erianin, the effective ingredient of gorgon fruit is cyclo(profilum), and the effective ingredient of cortex cinnamomi is cinnamaldehyde.

The invention relates to a Chinese traditional medicine active extract, a preparation method thereof and an application thereof, particularly relates to an effective part extracted from a Chinese traditional medicine Qinglongyi, its preparation method and its application. The Qinglongyi active extract is prepared by the following steps of ethanol diacolation, reflux, ultrasonic extraction, CO2 supercritical extraction, ethanol precipitation, elution, interception, reflux, concentration, dryness and the like. According to the invention, the anticancer activity of the Qinglongyi effective part is taken as an index for screening the effective part of Qinglongyi, efficacy tests are carried out by using the extract with different contents, the result proves that an effective component in the Qinglongyi active extract for treating cancer is total naphthoquinone; the efficacy test result proves that an effective component for anti-inflammatory analgesic effect is total flavonoid, total tannin and polar micromolecules; a substrate for improving immune function is polysaccharide.

The medicinal composition of effective parts of paeonol, its preparation method and application, is characterized in that the medicinal composition contains 10-40% of paeonol and 10-50% of paeonol total glycosides in terms of weight percentage; wherein, paeonol The total amount of phenol and total paeonol glycosides is not less than 50%. The preparation method is to soak paeonol medicinal material powder or decoction pieces in water, heat and distill, and place the distillate under cooling to precipitate and crystallize paeonol; Solution extraction, the extract and the filtrate are put on a macroporous adsorption resin column, firstly eluted with water, then with alcohol, and the alcohol eluate is collected; the alcohol is recovered under reduced pressure, concentrated and dried to obtain paeonol total glycosides; paeonol and The total glycosides of paeonol are mixed to prepare the composition of effective parts of paeonol. The effective part composition of paeonol cortex of the invention can be used to prepare medicines for preventing and treating fat metabolism diseases and cardiovascular and cerebrovascular diseases.

The invention relates to the novel use of pharmaceutical preparations in the field of pharmacy, more specifically the use of barrenwort flavones and barrenwort glycosides monomers as active components in preparing medicament for preventing and treating suppression. Pharmaceutical test shows that, the barrenwort flavones and barrenwort glycosides monomer can appreciably shorten rat's tail suspension time and forced swimming standby time, reverse the decrease of mouse sucrose consumption caused by CMS, suppress animal brain monoamines oxidation enzyme an and B, thus achieving the purpose of suppression resistance.

The invention relates to the technical field of traditional Chinese medicines, and particularly discloses a medicinal composition for treating hypertension and an application thereof. The medicinal composition comprises the following components by weight: 80-200g of red-rooted salvia root extract, 50-120g of tall gastrodia tuber extract, 40-200g of eucommia ulmoides leaf extract, 100-500g of natural dispersing agent and 10-50g of natural suspending agent. Through synergistic effect among various Chinese medicinal extracts, the medicinal value of each extract is increased, the dose of each Chinese medicinal extract for achieving the same medicinal effect is reduced, and the defects of a large number of taking forms, large dosage, slow response, gastrointestinal tract discomfort and the like in the conventional oral antihypertensive Chinese medicinal composition are overcome. Meanwhile, a special production process is adopted, and pure natural extracts such as the dispersing agent are taken as medicinal adjuvants, so that the mouthfeel of the medicine is improved. Compared with other products of the same type, the medicinal composition has the advantages of no bitterness and convenience in taking, and the compliance of patients is improved.

An antiiflammatory, antirheumatic and antalgic ointment contains the extract of Chinese monkshood rhizome, matrix, percutaneous absorption promoter, and antiseptic. Its advantages are high curative effect and low by-effect.

The invention discloses a human anti-rabies virus neutralizing antibody as well as the preparation method and the application thereof. The heavy chain variable region and the light chain variable region of the antibody respectively have an amino acid sequence represented by sequence 2 and sequence 4 in a sequence list, and the heavy chain variable region and the light chain variable region of a modified body of the antibody irrespectively have an amino acid sequence represented by sequence 8 and sequence 10 in the sequence list. The antibody is prepared according to the following steps: firstly, preparing a CDR region, a variable region, IgG section or the whole genes of the antibody by molecular biology or other methods; expressing in prokaryotic cells such as Escherichia coli, eukaryotic cells such as yeast, insect cells, plant cells or mammal cells such as CHO; and purifying to obtain the antibody. The antibody has the advantages of high specific neutralization activity, high affinity and no toxic and side effects, suits prevention and emergency treatment of rabies as well as detection of rabies virus, and has excellent application prospect.

The invention discloses new application of an extract of Chinese angelica and szechuan lovage rhizome composition to the preparation of a medicament for promoting ovary granular cell proliferation. Intensive study is performed on a large quantity of ancient and modern prescriptions and traditional Chinese medicine application data, traditional Chinese medicine resources are fully utilized according to a traditional Chinese medicine theory and the pathogenesis of ovarian functional disturbance and insufficient growth of ovary granular cells and a large number of pharmacological tests are performed based on the current researches of Chinese angelica and szechuan lovage rhizome, so that new application of the Chinese angelica and szechuan lovage rhizome to the treatment of ovarian functional disturbance and the promotion of ovary granular cell proliferation; moreover, the weight ratio of the Chinese angelica and szechuan lovage rhizome composition with the highest activity is screened through a large quantity of experiments. When clinically taken as a medicament for treating ovarian functional disturbance and promoting ovary granular cell proliferation, the extract has the advantages of good curative effect, definite active ingredient, small side effect, convenience of taking and the like.

A Chinese medicine for treating diabetes features that its main component is the red peonyí»s glycoside extracted from red peony root. Its preparing process and the forms of its product are also disclosed.

The medicine composition for treating cardiac and cerebral vascular diseases has ligustilide and volatile grassleaved sweetflag rhizome oil in the weight ratio of 1 to 0.5-20 as effective medicinal components and contains also borneol and musk and pharmaceutically acceptable supplementary material. Test proves the synergistic effect between ligustilide and volatile grassleaved sweetflag rhizome oil as well as of borneol and musk in resisting cerebral ischemia reperfusion injury and resisting anoxia.

The invention discloses semen hoveniae extracts with a liver protection function and an extraction and separation method and application thereof. The extracts comprise, by mass, 10-99% of total flavone C-glycoside, wherein the main flavone C-glycoside comprises six kinds of flavone C-glycoside including vitexin 2''-O-beta-D-glucopyranoside, spinosin, poloretin-3', 5'-di-C-beta-D-glucopyranoside, 6'' '-acetyl spinosin, 6'' '-p- hydroxyl-cinnamoyl-spinosin and 6'' '- sinapoyl-spinosin. The total flavone C-glycoside is extracted from semen hoveniae and used for preventing and treating acute and chronic hepatitis and alcoholic liver disease; compositions at effective parts are accurate; toxicity is small; the pharmacological action is high, and a good medicine prospect is achieved. The extracts and acceptable agents on pharmacy are adopted to be prepared into various dosage forms through a conventional method, like tablets, pills, capsules and granules. The dosage is 200-800 mg / each person / day.

An application of the phenylpropylethylene curcumin or the composition of curcumin, demethoxy curcumin and bidemethoxy curcumin in the medicine or health-care food for treating depression is disclosed.

A Chinese medicine for treating cardiovascular and cerebrovascular diseases and ischemic apoplex is prepared from red peony root, capejasmine fruit and astragalus root. The prescription and preparing process of its injection and its other clinical forms are also disclosed.

The invention discloses composite anti-fatigue beverage containing plant extracts. The beverage disclosed by the invention consists of salidroside, rhodiola rosavin, astragalus saponin, hawthorn flavone, caffeine, taurine, inositol, nicotinamide, lysine, vitamins, citric acid, cane sugar, juice and water according to a reasonable ratio. The anti-fatigue beverage disclosed by the invention has the effects of resisting fatigue and improving the immunity.

A composition for preventing and treating hyperuricemia and gout contains at least two of the volatile oil of cinammon twigs, the total flavone of biota tops and total alkaloid of Chuan-xiong rhizome. Its advantages are stable curative effect and high safety.

A medicnie for treating rhinitis and nasosinusitis is prepared from houttuynia, polysorbide, sodium hydrogen sulfite, antiseptic, sodium chloride, purified water and pH regulator through distilling houttuynia to extract its active components, proportionally mixing them with others, filtering, and steam sterilizing.